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Ocular Immunology and Inflammation Volume 31, 2023 - Issue 1
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Letters to the Editor

Ripasudil Eyedrops Ameliorated Bullous Keratopathy Complicated with Cytomegalovirus Corneal Endotheliitis: A Case Report

Masaaki Yoshidaa Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, JapanView further author information
, MD,
Shunji Yokokuraa Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, JapanCorrespondence[email protected]
View further author information
, MD, PhD,
Takehiro Hariyaa Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, JapanView further author information
, MD, PhD,
Wataru Kobayashia Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan;b Department of Retinal Disease Control, Tohoku University Graduate School of Medicine, Sendai, JapanView further author information
, MD, PhD,
Kazuki Hashimotoa Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, JapanView further author information
, MD &
Toru Nakazawaa Department of Ophthalmology, Tohoku University Graduate School of Medicine, Sendai, Japan;b Department of Retinal Disease Control, Tohoku University Graduate School of Medicine, Sendai, Japan;c Collaborative Program for Ophthalmic Drug Discovery, Tohoku University Graduate School of Medicine, Sendai, Japan;d Department of Advanced Ophthalmic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan;e Department of Ophthalmic Imaging and Information Analytics, Tohoku University Graduate School of Medicine, Sendai, JapanView further author information
, MD, PhD
Pages 207-210 | Received 02 Jun 2021, Accepted 28 Sep 2021, Published online: 02 Nov 2021

References

  • Tanihara H, Kakuda T, Sano T, et al. Safety and efficacy of Ripasudil in Japanese patients with glaucoma or ocular hypertension: 3-month interim analysis of ROCK-J, a post-marketing surveillance study. Adv Ther. 2019;36(2):333–343. doi:10.1007/s12325-018-0863-1.
  • Okumura N, Okazaki Y, Inoue R, et al. Effect of the rho-associated kinase inhibitor eye drop (Ripasudil) on Corneal endothelial wound healing. Invest Ophthalmol Vis Sci. 2016;57(3):1284–1292. doi:10.1167/iovs.15-18586.
  • Okumura N, Fujii K, Kagami T, et al. Activation of the Rho/Rho kinase signaling pathway is involved in cell death of corneal endothelium. Invest Ophthalmol Vis Sci. 2016;57(15):6843–6851. doi:10.1167/iovs.16-20123.
  • Syed ZA, Rapuano CJ. Rho kinase (ROCK) inhibitors in the management of corneal endothelial disease. Curr Opin Ophthalmol. 2021;32(3):268–274. doi:10.1097/ICU.0000000000000748.
  • Koizumi N, Inatomi T, Suzuki T, et al. Clinical features and management of cytomegalovirus corneal endotheliitis: analysis of 106 cases from the Japan corneal endotheliitis study. Br J Ophthalmol. 2015;99(1):54–58. doi:10.1136/bjophthalmol-2013-304625.
  • Igarashi N, Honjo M, Kaburaki T, Aihara M. Effects of ROCK inhibitors on apoptosis of corneal endothelial cells in CMV-positive posner⇓schlossman syndrome patients. Investig Ophthalmol Vis Sci. 2020;61(10):5. doi:10.1167/iovs.61.10.5.
  • Wong AHY, Kua WN, Young AL, Wan KH. Management of cytomegalovirus corneal endotheliitis. Eye Vis. 2021;8(1):1–13. doi:10.1186/s40662-020-00226-y.
  • Fan N-W, Chung Y-C, Liu Y-C, Liu CJ-L, Kuo Y-S, Lin P-Y. Long-term topical ganciclovir and corticosteroids preserve corneal endothelial function in cytomegalovirus corneal endotheliitis. Cornea. 2016;35(5):596–601. doi:10.1097/ICO.0000000000000791.
  • Maruyama K, Maruyama Y, Sugita S, et al. Characteristics of cases needing advanced treatment for intractable Posner–Schlossman syndrome. BMC Ophthalmol. 2017;17(1):45. doi:10.1186/s12886-017-0438-y.
  • Igarashi N, Honjo M, Yamagishi R, et al. Involvement of autotaxin in the pathophysiology of elevated intraocular pressure in Posner-Schlossman syndrome. Sci Rep. 2020;10(1):1–13. doi:10.1038/s41598-020-63284-1.

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