White matter changes on ct brain scan are associated with neurobehavioral dysfunction in children with symptomatic HIV disease

References

• Aylward , E. H. , Butz , A. M. , Hutton , N. , Joyner , M. L. and Vogelhut , J. W. 1992 . Cognitive and motor development in infants at risk for human immunodeficiency virus . American Journal of Diseases of Children , 146 : 218 – 222 .
   PubMedGoogle Scholar
• Bayley , N. 1969 . Manual for the Barley Scales of Infant Development , San Antonio, TX : The Psychological Corporation .
   Google Scholar
• Beery , K. E. 1989 . The developmental test of Visual-Motor Integration, VMI, , 3rd ed. rev. , Cleveland, OH : Modern Curriculum Press .
   Google Scholar
• Belman , A. L. , Brouwers , P. and Moss , H. 1992 . “ HIV-1 and the central nervous system ” . In Child and adolescent neurology for psychiatrists , Edited by: Kaufman , D. M. , Solomon , G. E. and Pfeffer , C. R. 238 – 253 . Baltimore : Williams & Wilkins .
   Google Scholar
• Bose , S. , Moss , H. , Brouwers , P. , Pizzo , P. and Lorion , R. 1994 . Psychological adjustment of HIV-infected school age children . Journal of Developmental and Behavioral Pediatrics , 15 : S26 – S33 .
   PubMed Web of Science ®Google Scholar
• Bornstein , R. A. , Chakeres , D. , Brogan , M. , Nasrallah , H. , Fass , R. J. , Para , M. and Whitacre , C. 1992 . Magnetic Resonance Imaging of white matter lesions in HIV infection . Journal of Neuropsychiatry and Clinical Neurosciences , 4 : 174 – 178 .
   Google Scholar
• Brouwers , P. , Belman , A. and Epstein , L. 1994 . “ Organ specific complications: Central nervous system involvement: Manifestations, evaluation, and pathogenesis ” . In Pediatric AIDS: The challenge of HIV Infection in infants, children, and adolescents, , 2nd ed , Edited by: Pizzo , P. A. and Wilfert , C. M. 433 – 455 . Baltimore : Williams & Wilkins .
   Google Scholar
• Brouwers , P. , DeCarli , C. , Tudor-Williams , G. , Civitello , L. , Moss , H. and Pizzo , P. 1994 . Interrelations among patterns of change in neurocognitive, CT brain imaging, and CD4 measures associated with antiretroviral therapy in children with symptomatic HIV infection . Advances in Neuroimmunology , 4 : 223 – 231 .
   PubMedGoogle Scholar
• Brouwers , P. , DeCarli , C. , Civitello , L. , Moss , H. , Wolters , P. and Pizzo , P. 1995 . Correlation between CT-Brain scan abnormalitiies and neuropsychological function in children with symptomatic HIV disease . Archives of Neurology , 52 : 39 – 44 .
   PubMed Web of Science ®Google Scholar
• Brouwers , P. , Heyes , M. , Moss , H. , Wolters , P. , Poplack , D. , Markey , S. and Pizzo , P. 1993 . Quinolinic acid in the cerebrospinal fluid of children with symptomatic HIV-1 Disease: Relationships to clinical status and therapeutic response . The Journal of Infectious Diseases , 168 : 1380 – 1386 .
   Google Scholar
• Brouwers , P. , Moss , H. , Wolters , P. , Eddy , J. , Balis , F. , Poplack , D. and Pizzo , P. A. 1990 . Effect of continuous-infusion Zidovudine therapy on neuropsychologic functioning in children with symptomatic human immuno-deficiency virus infection . Journal of Pediatrics , 117 : 980 – 985 .
   PubMed Web of Science ®Google Scholar
• Brouwers , P. , Moss , H. , Wolters , P. , El-Amin , D. , Tassone , E. and Pizzo , P. 1992 . Neuro-behavioral typology of school-age children with symptomatic HIV disease [Abstract] . Journal of Clinical and Experimental Neuropsychology , 14 : 113
   Google Scholar
• Brouwers , P. , Moss , H. , Wolters , P. and Schmitt , F. 1994 . “ Developmental deficits and behavioral change in pediatric AIDS ” . In Neuropsychology of HIV infection: Current research and new directions , Edited by: Grant , I. and Martin , A. 310 – 338 . New York : Oxford University Press .
   Google Scholar
• Budka , H. 1991 . Neuropathology of human immunodeficiency virus infection . Brain Pathology , 1 : 163 – 175 .
   PubMed Web of Science ®Google Scholar
• Butler , K. M. , Husson , R. N. , Balis , F. M. , Brouwers , P. , Eddy , J. , El-Amin , D. , Gress , J. , Hawkins , M. , Jarosinski , P. , Moss , H. , Poplack , D. , Santacroce , S. , Venzon , D. , Wiener , L. , Wolters , P. and Pizzo , P. A. 1991 . Dideoxyinosine (ddI) in symptomatic HIV-infected children: A phase I-II study . New England Journal of Medicine , 324 : 137 – 144 .
   PubMed Web of Science ®Google Scholar
• Chamberlain , M. C. , Nichols , S. L. and Chase , C. H. 1991 . Pediatric AIDS: Comparative cranial MRI and CT scans . Pediatric Neurology , 7 : 357 – 362 .
   PubMed Web of Science ®Google Scholar
• Civitello , L. A. , Brouwers , P. and Pizzo , P. A. 1993 . Neurological and neuropsychological manifestations in 120 children with symptomatic Human Immunodeficiency Virus infection [Abstract] . Annals of Neurology , 34 : 481
   Google Scholar
• DeCarli , C. , Civitello , L. A. , Brouwers , P. and Pizzo , P. A. 1993 . The prevalence of computed axial tomographic abnormalities of the cerebrum in 100 consecutive children symptomatic with the human immunodeficiency virus . Annals of Neurology , 34 : 198 – 205 .
   PubMed Web of Science ®Google Scholar
• Dietrich , R. B. , Bradley , W. G. , Zaragoza , E. J. , Otto , R. J. , Taira , R. K. , Wilson , G. H. and Kangarloo , H. 1988 . MR evaluation of early myelination patterns in normal and developmentally delayed infants . American Journal of Neuroradiology , 9 : 69 – 76 .
   Google Scholar
• Dunn , L. M. and Dunn , L. M. 1981 . Peabody Picture Vocabulary Test-Revised , Circle Pines, MN : American Guidance Service .
   Google Scholar
• Epstein , L. G. , Goudsmit , J. , Paul , D. A. , Morrison , S. H. , Connor , E. M. , Oleske , J. M. and Holland , B. 1987 . Expression of human immunodeficiency virus in cerebrospinal fluid of children with progressive encephalopathy . Annals of Neurology , 2 : 397 – 401 .
   Google Scholar
• Epstein , L. G. , Sharer , L. R. , Oleske , J. M. , Connor , E. M. , Goudsmit , J. , Bagdon , L. , Robert-Guroff , M. and Koenigsberger , M. R. 1986 . Neurologic manifestations of human immunodeficiency virus infection in children . Pediatrics , 78 : 678 – 687 .
   PubMed Web of Science ®Google Scholar
• European Collaborative Study . 1992 . Age-related standards for T lymphocyte subsets based on uninfected children born to human immunodeficinecy virus infected women . Pediatric Infectious Disease Journal , 11 : 1018 – 1026 .
   PubMed Web of Science ®Google Scholar
• Gardner , M. F. 1979 . Expressive One-Word Picture Vocabulary Test , Novato, CA : Academic Therapy Publications .
   Google Scholar
• Ghaziuddin , M. , Tsai , L. , Eilers , L. and Ghaziuddin , N. 1992 . Autism and herpes simplex encephalitis . Journal of Autism and Developmental Disorders , 22 : 107 – 113 .
   PubMedGoogle Scholar
• Gillberg , C. 1991 . Autistic Syndrome with onset at age 31; Herpes encephalitis as a possible model for childhood autism . Developmental Medicine and Child Neurology , 33 : 920 – 924 .
   PubMed Web of Science ®Google Scholar
• Hittelman , J. 1990 . “ Neurodevelopmental aspects of HIV infection ” . In Brain in pediatric AIDS , Edited by: Kozlowski , P. B. , Snider , D. A. , Vietze , P. M. and Wisneiwski , H. M. 64 – 71 . Basel : Karger .
   Google Scholar
• Ho , D. D. , Rota , T. R. , Schooley , R. T. , Kaplan , J. C. , Allan , J. D. , Groopman , J. E. , Resnick , L. , Flesen-stein , D. , Andrews , C. A. and Hirsch , M. S. 1985 . Isolation of HTLV-III from cerebrospinal fluid and neural tissues of patients with neurologic syndromes related to the acquired nimmunodeficiency syndrome . The New England Journal of Medicine , 313 : 1493 – 1497 .
   PubMed Web of Science ®Google Scholar
• Husson , R. N. , Mueller , B. U. , Farley , M. , Woods , L. , Goldsmith , J. , Kovacs , A. , Ono , J. , Lewis , L. L. , Balis , F. M. , Brouwers , P. , Avramis , V. , Church , J. , Butler , K. M. , Rasheed , S. , Jarosinski , P. , Venzon , D. and Pizzo , P. A. 1994 . Zidovudine and didanosine combination therapy in children with Human Immunodeficiency Virus Infection . Pediatrics , 93 : 316 – 322 .
   PubMed Web of Science ®Google Scholar
• Kauffman , W. M. , Sivit , C. J. , Fitz , C. R. , Rakusan , T. A. , Herzog , K. and Chandra , R. S. 1992 . CT and MR evaluation of intracranial involvement in pediatric HIV infection: A clinical-imaging correlation . American Journal of Neuroradiology , 13 : 949 – 957 .
   PubMed Web of Science ®Google Scholar
• Kinney , H. C. , Brody , B. A. , Kloman , A. S. and Gilles , F. H. 1988 . Sequence of central nervous system myelinatin in human infancy: Patterns of myelination in autopsied infants . Journal of Neuropathology and Experimental Neurology , 47 : 217 – 234 .
   PubMed Web of Science ®Google Scholar
• Loveland , K. A. , Stehbens , J. , Contant , C. , Bordeaux , J. D. , Sirois , P. , Bell , T. E. and Hill , S. 1994 . Hemophilia growth and development study: Baseline neurodevelopmental findings . Journal of Pediatric Psychology , 19 : 223 – 239 .
   PubMed Web of Science ®Google Scholar
• McCarthy , D. 1972 . The McCarthy Scales of Children''s Abilities , New York : Psychological Corporation .
   Google Scholar
• Mintz , M. , Rapaport , R. , Oleske , J. M. , Connor , E. M. , Koenigsberger , M. R. , Denny , T. and Epstein , L. G. 1989 . Elevated serum levels of tumor necrosis factor are associated with progressive encephalopathy in children with acquired immunodeficiency syndrome . American Journal of Disease of Children , 143 : 771 – 774 .
   Google Scholar
• Mizrachi , Y. , Zeira , M. , Shahabuddin , M. , Li , G. , Sinangil , F. and Volsky , D. J. 1991 . Efficient binding, fusion and entry of HIV-1 into CD4-negative neural cells: A mechanism for neuropathogenesis in AIDS . Bulletin d' Institute Pasteur , 89 : 81 – 96 .
   Google Scholar
• Moss , H. A. , Brouwers , P. , Wolters , P. L. , Wiener , L. , Hersh , S. P. and Pizzo , P. A. 1994 . The development of a Q-sort behavior rating procedure for pediatric HIV patients . Journal of Pediatric Psychology , 19 : 27 – 46 .
   PubMed Web of Science ®Google Scholar
• Murray , R. M. , Jones , P. , O'Callaghan , E. , Takei , N. and Sham , P. 1992 . Genes, viruses and neurodevelopmental schizophrenia . Journal of Psychiatric Research , 26 : 225 – 235 .
   PubMed Web of Science ®Google Scholar
• Pizzo , P. , Eddy , J. , Falloon , J. , Balis , F. , Murphy , R. , Moss , H. , Wolters , P. , Brouwers , P. , Jarosinski , P. , Rubin , M. , Broder , S. , Yarchoan , R. , Brunetti , A. , Maha , M. , Nusinoff-Lehrman , S. and Poplack , D. 1988 . Effect of continuous intravenous infusion of zidovudine (AZT) in children with symptomatic HIV infection . New England Journal of Medicine , 319 : 889 – 896 .
   PubMed Web of Science ®Google Scholar
• Pizzo , P. , Butler , K. , Balis , F. , Brouwers , E. , Hawkins , M. , Eddy , J. , Einloth , M. , Falloon , J. , Husson , R. , Jarosinski , P. , Meer , J. , Moss , H. , Poplack , D. , Santacroce , S. , Wiener , L. and Wolters , P. 1990 . Dideoxycytidine alone and in an alternating schedule with zidovudine in children with symptomatic human immunodeficiency virus infection . The Journal of Pediatrics , 117 : 799 – 808 .
   PubMedGoogle Scholar
• Price , D. B. , Inglese , C. M. , Jacobs , J. , Haller , J. O. , Kramer , J. , Hotson , G. C. , Loh , J. P. , Schlusselberg , D. , Menez-Bautista , R. , Rose , A. L. and Fikrig , S. 1988 . Pediatric AIDS: Neuroradiologic and neurodevelopmental findings . Pediatric Radiology , 18 : 445 – 448 .
   Google Scholar
• Rourke , B. P. 1989 . Nonverbal learning disabilities: The syndrome and the model , New York : Guilford Press .
   Google Scholar
• Sharer , L. R. , Epstein , L. G. , Cho , E. S. , Joshi , V. V. , Meyenhofer , M. F. , Rankin , L. F. and Petito , C. K. 1986 . Pathologic features of AIDS encephalopathy in children: Evidence for LAV/HTLV-III infection of the brain . Human Pathology , 17 : 271 – 284 .
   PubMed Web of Science ®Google Scholar
• Sharer , L. R. , Michaels , J. , Murphey-Corb , M. , Hu , F.-S. , Kuebler , D. J. , Martin , L. N. and Baskin , G. B. 1991 . Serial pathogenesis study of SIV brain infection . Journal of Medical Primatology , 20 : 211 – 217 .
   Google Scholar
• Sparrow , S. , Balla , D. and Cicchetti , D. 1984 . Vineland Adaptive Behavior Scales , Circle Pines, MN : American Guidance Service .
   Google Scholar
• Swedo , S. E. , Leonard , H. L. and Kiessling , L. S. 1994 . Speculations on antineuronal antibody-mediated neuropsychiatric disorders of childhood . Pediatrics , 93 : 323 – 326 .
   PubMed Web of Science ®Google Scholar
• Tardieu , M. , Blanche , S. and Brunelle , F. . Cerebral magnetic resonance imaging studies in HIV-1 infected children born to seropositive mothers . Neuroscience of HIV-1 infection. Satellite to VII International Conference on AIDS . Padova. pp. 60 Abstract
   Google Scholar
• Taylor , H. G. 1987 . Childhood sequelae of early neurological disorders: A contemporary perspective . Developmental Neuropsychology , 3 : 153 – 164 .
   Web of Science ®Google Scholar
• van der Knaap , M. S. , Valk , J. , Bakker , C. J. , Schooneveld , M. , Faber , J. A. , Willemse , J. and Gooskens , R. H. 1991 . Myelination as an expression of the functional maturity of the brain . Developmental Medicine & Child Neurology , 33 : 849 – 57 .
   PubMed Web of Science ®Google Scholar
• Waternaux , C. 1991 . “ Statistical considerations for the analysis of neurobehavioral trials ” . In Handbook of clinical trials, The neurobehavioral approach , Edited by: Mohr , E. and Brouwers , P. 81 – 86 . Amsterdam/Lisse : Swets & Zeitlinger .
   Google Scholar
• Wechsler , D. 1974 . Manual for the Wechsler Intelligence Scale for Children , New York : Psychological Corporation .
   Google Scholar
• Whitt , J. K. , Hooper , S. R. , Tennison , M. B. , Robertson , W. T. , Golds , S. H. , Burchinal , M. , Wells , R. , McMillan , C. , Whaley , R. A. , Combest , J. and Hall , C. D. 1993 . Neuropsychologic functioning of human immunodeficiency virus-infected children with hemophilia . Journal of Pediatrics , 122 : 52 – 59 .
   PubMed Web of Science ®Google Scholar
• Wolters , P. L. , Brouwers , P. , Moss , H. and Pizzo , P. 1994 . Adaptive behavior of children with symptomatic HIV infection before and after Zidovudine therapy . Journal of Pediatric Psychology , 19 : 47 – 61 .
   PubMedGoogle Scholar
• Wolters , P. L. , Brouwers , P. , Moss , H. A. and Pizzo , P. A. 1995 . Differential receptive and expressive language functioning of children with symptomatic HIV disease and relation to CT scan brain abnormalities . Pediatrics , 95 : 112 – 119 .
   PubMed Web of Science ®Google Scholar