100
Views
0
CrossRef citations to date
0
Altmetric
RANK POLYMORPHISM AND HIGH RISK OF LUMBAR SPINE OSTEOPOROSIS

High risk of lumbar spine osteoporosis with the RANK rs3018362 polymorphism

, , , , , & ORCID Icon show all
Pages 981-984 | Received 26 Mar 2019, Accepted 28 Apr 2019, Published online: 24 May 2019

References

  • Kanis JA, on behalf of the World Health Organization Scientific Group. Assessment of osteoporosis at the primary health-care level. Technical Report. World Health Organization Collaborating Centre for Metabolic Bone Diseases. United Kingdom: University of Sheffield; 2007.
  • Clark P, Tamayo JA, Cisneros F, et al. Epidemiology of osteoporosis in Mexico. Present and future directions. Rev Invest Clin. 2013;65:183–191.
  • Alonso N, Ralston SH. Unveiling the mysteries of the genetics of osteoporosis. J Endocrinol Invest. 2014;37:925–934.
  • Wu S, Liu Y, Zhang L, et al. Genome-wide approaches for identifying genetic risk factors for osteoporosis. Genome Med. 2013;5:44.
  • Roshandel D, Holliday KL, Pye SR, et al. Genetic variation in the RANKL/RANK/OPG signaling pathway is associated with bone turnover and bone mineral density in men. J Bone Miner Res. 2010;25:1830–1838.
  • Mohamed RH, Mohamed RH, El-Shahawy EE. Relationship between RANK and RANKL gene polymorphisms with osteoporosis in rheumatoid arthritis patients. Genet Test Mol Biomarkers. 2016;20:249–254.
  • Estrada K, Styrkarsdottir U, Evangelou E, et al. Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet. 2012;44:491–501.
  • Styrkarsdottir U, Halldorsson BV, Gretarsdottir S, et al. Multiple genetic loci for bone mineral density and fractures. N Engl J Med. 2008;358:2355–2365.
  • Styrkarsdottir U, Halldorsson BV, Gretarsdottir S, et al. New sequence variants associated with bone mineral density. Nat Genet. 2009;41:15–17.
  • Shang M, Lin L, Cui H. Association of genetic polymorphisms of RANK, RANKL and OPG with bone mineral density in Chinese peri- and postmenopausal women. Clin Biochem. 2013;46:1493–1501.
  • Casas-Avila L, Ponce de León-Suárez V, Peñaloza-Espinosa RI, et al. The RANKL rs12585014 polymorphism is associated with age at menarche in postmenopausal women with hip fracture. Gynecol Endocrinol. 2018;34:1031–1034.
  • Ho-Pham LT, Nguyen ND, Lai TQ, et al. Contributions of lean mass and fat mass to bone mineral density: a study in postmenopausal women. BMC Musculoskelet Disord. 2010;11:59.
  • Alonso AC, Gonçalves TA, Almeida J, et al. Relationship between bone mineral density and body composition in elderly. Acta Ortop Bras. 2018;26:27–29.
  • Reid IR. Fat and bone. Arch Biochem Biophys. 2010;503:20–27.
  • Chevalley T, Bonjour JP, Ferrari S, et al. Influence of age at menarche on forearm bone microstructure in healthy young women. J Clin Endocrinol Metab. 2008;93:2594–2601.
  • Haugeberg G, Uhlig T, Falch JA, et al. Bone mineral density and frequency of osteoporosis in female patients with rheumatoid arthritis: results from 394 patients in the Oslo County Rheumatoid Arthritis register. Arthritis Rheum. 2000;43:522–530.
  • van Staa TP, Geusens P, Bijlsma JW, et al. Clinical assessment of the long-term risk of fracture in patients with rheumatoid arthritis. Arthritis Rheum. 2006;54:3104–3112.
  • Paternoster L, Ohlsson C, Sayers A, et al. OPG and RANK polymorphisms are both associated with cortical bone mineral density: findings from a metaanalysis of the Avon longitudinal study of parents and children and Gothenburg osteoporosis and obesity determinants cohorts. J Clin Endocrinol Metab. 2010;95:3940–3948.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.