313
Views
17
CrossRef citations to date
0
Altmetric
HIGH CONCENTRATION OF CHEMERIN MAY LEAD TO POOR IVF OUTCOME IN PCOS: A PILOT STUDY

High concentration of chemerin caused by ovarian hyperandrogenism may lead to poor IVF outcome in polycystic ovary syndrome: a pilot study

, , , , , , , , & show all
Pages 1072-1077 | Received 28 Jan 2019, Accepted 19 May 2019, Published online: 03 Jun 2019

References

  • Dimitriadis GK, Kyrou I, Randeva HS. Polycystic ovary syndrome as a proinflammatory state: the role of adipokines. Curr Pharm Des. 2016;22:5535–5546.
  • Shorakae S, Teede H, de Courten B, et al. The emerging role of chronic low-grade inflammation in the pathophysiology of polycystic ovary syndrome. Semin Reprod Med. 2015;33:257–269.
  • Bideci A, Camurdan MO, Yeşilkaya E, et al. Serum ghrelin, leptin and resistin levels in adolescent girls with polycystic ovary syndrome. J Obstet Gynaecol Res. 2008;34:578–584.
  • Carmina E, Orio F, Palomba S, et al. Evidence for altered adipocyte function in polycystic ovary syndrome. Eur J Endocrinol. 2005;152:389–394.
  • Spritzer PM, Lecke SB, Satler F, et al. Adipose tissue dysfunction, adipokines, and low-grade chronic inflammation in polycystic ovary syndrome. Reproduction (Cambridge, England). 2015;149:R219–27.
  • Guzel EC, Celik C, Abali R, et al. Omentin and chemerin and their association with obesity in women with polycystic ovary syndrome. Gynecol Endocrinol. 2014;30:419–422.
  • Huang R, Yue J, Sun Y, et al. Increased serum chemerin concentrations in patients with polycystic ovary syndrome: relationship between insulin resistance and ovarian volume. Clin Chim Acta. 2015;450:366–369.
  • Reverchon M, Cornuau M, Rame C, et al. Chemerin inhibits IGF-1-induced progesterone and estradiol secretion in human granulosa cells. Hum Reprod (Oxford, England). 2012;27:1790–1800.
  • Pigny P, Merlen E, Robert Y, et al. Elevated serum level of anti-mullerian hormone in patients with polycystic ovary syndrome: relationship to the ovarian follicle excess and to the follicular arrest. J Clin Endocrinol Metab. 2003;88:5957–5962.
  • Richards JS, Russell DL, Ochsner S, et al. Novel signaling pathways that control ovarian follicular development, ovulation, and luteinization. Recent Prog Horm Res. 2002;57:195–220.
  • Reverchon M, Bertoldo MJ, Rame C, et al. CHEMERIN (RARRES2) decreases in vitro granulosa cell steroidogenesis and blocks oocyte meiotic progression in bovine species. Biol Reprod. 2014;90:102.
  • Azziz R, Sanchez LA, Knochenhauer ES, et al. Androgen excess in women: experience with over 1000 consecutive patients. J Clin Endocrinol Metab. 2004;89:453–462.
  • Wang L, Zhong Y, Ding Y, et al. Elevated serum chemerin in Chinese women with hyperandrogenic PCOS. Gynecol Endocrinol. 2014;30:746–750.
  • Wang Q, Kim JY, Xue K, et al. Chemerin, a novel regulator of follicular steroidogenesis and its potential involvement in polycystic ovarian syndrome. Endocrinology. 2012;153:5600–5611.
  • Lima PDA, Nivet AL, Wang Q, et al. Polycystic ovary syndrome: possible involvement of androgen-induced, chemerin-mediated ovarian recruitment of monocytes/macrophages. Biol Reprod. 2018; 99:838–852.
  • Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004;81:19–25.
  • Shi Y, Wei D, Liang X, et al. Live birth after fresh embryo transfer vs elective embryo cryopreservation/frozen embryo transfer in women with polycystic ovary syndrome undergoing IVF (FreFro-PCOS): study protocol for a multicenter, prospective, randomized controlled clinical trial. Trials. 2014;15:154.
  • Dang X, Zhu Q, He Y, et al. IL-1beta upregulates StAR and progesterone production through the ERK1/2- and p38-mediated CREB signaling pathways in human granulosa-lutein cells. Endocrinology. 2017;158:3281–3291.
  • Puissant F, Van Rysselberge M, Barlow P, et al. Embryo scoring as a prognostic tool in IVF treatment. Hum Reprod (Oxford, England). 1987;2:705–708.
  • Teede H, Deeks A, Moran L. Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan. BMC Med. 2010;30:8.
  • Chu SH, Lee MK, Ahn KY, et al. Chemerin and adiponectin contribute reciprocally to metabolic syndrome. PloS One. 2012;7:e34710.
  • Meder W, Wendland M, Busmann A, et al. Characterization of human circulating TIG2 as a ligand for the orphan receptor ChemR23. FEBS Lett. 2003;555:495–499.
  • Ehrmann DA. Polycystic ovary syndrome. N Engl J Med. 2005;352:1223–1236.
  • Kim JY, Xue K, Cao M, et al. Chemerin suppresses ovarian follicular development and its potential involvement in follicular arrest in rats treated chronically with dihydrotestosterone. Endocrinology. 2013;154:2912–2923.
  • Barber TM, McCarthy MI, Wass JA, et al. Obesity and polycystic ovary syndrome. Clin Endocrinol. 2006;65:137–145.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.