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UTERINE FIBROIDS

Vitamin D and green tea extracts for the treatment of uterine fibroids in late reproductive life: a pilot, prospective, daily-diary based study

ORCID Icon, , , &
Pages 63-67 | Received 22 May 2021, Accepted 07 Oct 2021, Published online: 16 Oct 2021

References

  • Donnez J, Dolmans MM. Uterine fibroid management: from the present to the future. Hum Reprod Update. 2016;22(6):665–686.
  • Wise LA, Laughlin-Tommaso SK. Epidemiology of uterine fibroids: from menarche to menopause. Clin Obstet Gynecol. 2016;59(1):2–24.
  • Borah BJ, Nicholson WK, Bradley L, et al. The impact of uterine leiomyomas: a national survey of affected women. Am J Obstet Gynecol. 2013;209(4):319.e1-319–e20.
  • Sabry M, Halder SK, Allah AS, et al. Serum vitamin D3 level inversely correlates with uterine fibroid volume in different ethnic groups: a cross-sectional observational study. Int. J. Women’s Health. 2013;5:93–100.
  • Paffoni A, Somigliana E, Vigano P, et al. Vitamin D status in women with uterine leiomyomas. J. Clin Endocrinol Metab. 2013;98:1374–1378.
  • Xu F, Li F, Li L, et al. Vitamin D as a risk factor for the presence of asymptomatic uterine fibroids in premenopausal Han Chinese women. Fertil Steril. 2021;S0015-0282(20):32717–32715.
  • Baird DD, Hill MC, Schectman JM, et al. Vitamin D and the risk of uterine fibroids. Epidemiology. 2013;24(3):447–453.
  • Wise LA. Study of environment lifestyle and fibroids (self): advancing the field of fibroid epidemiology. J Women’s Health. 2015;24(11):862–864.
  • Halder SK, Osteen KG, Al-Hendy A. 1,25-dihydroxyvitamin D3 reduces extracellular matrix-associated protein expression in human uterine fibroid cells. Biol. Reprod. 2013;89:150.
  • Brakta S, Diamond JS, Al-Hendy A, et al. Role of vitamin D in uterine fibroid biology. Fertil Steril. 2015;104(3):698–706.
  • Bläuer M, Rovio PH, Ylikomi T, et al. Vitamin D inhibits myometrial and leiomyoma cell proliferation in vitro. Fertil Steril. 2009;91(5):1919–1925.
  • Graham HN. Green tea composition, consumption, and polyphenol chemistry. Prev Med. 1992;21(3):334–350.
  • Imai K, Suga K, Nakachi K. Cancer-preventive effects of drinking green tea among a japanese population. Prev Med. 1997;26(6):769–775.
  • Zhang D, Al-Hendy M, Richard-Davis G, et al. Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice. Am J Obstet Gynecol. 2010;202(3):289.e1-9–289.e9.
  • Ahmed RS, Liu G, Renzetti A, et al. Biological and mechanistic characterization of novel prodrugs of green tea polyphenol epigallocatechin gallate analogs in human leiomyoma cell lines. J Cell Biochem. 2016;117(10):2357–2369.
  • Zhang D, Rajaratnam V, Al-Hendy O, et al. Green tea extract inhibition of human leiomyoma cell proliferation is mediated via catechol-O-methyltransferase. Gynecol Obstet Invest. 2014;78(2):109–118.
  • Munro MG, Critchley HOD, Fraser IS. The two FIGO systems for normal and abnormal uterine bleeding symptoms and classification of causes of abnormal uterine bleeding in the reproductive years: 2018 revisions. Int J Gynaecol Obstet. 2018;143(3):393–408.
  • Soules MR, Sherman S, Parrott E, et al. Stages of reproductive aging workshop (STRAW). J Womens Health Gend Based Med. 2001;10(9):843–848.
  • Fascilla FD, Cramarossa P, Cannone R, et al. Ultrasound diagnosis of uterine myomas. Minerva Ginecol. 2016;68(3):297–312.
  • Gohari P, Berkowitz RL, Hobbins JC. Prediction of intrauterine growth retardation by determination of total intrauterine volume. Am J Obstet Gynecol. 1977;127(3):255–260.
  • Grandi G, De Fata R, Varliero F, et al. Contemporary prescriptions pattern of different dose levonorgestrel-releasing intrauterine systems in an Italian service for family planning. Gynecol Endocrinol. 2020;36(12):1086–1089.
  • Roshdy E, Rajaratnam V, Maitra S, et al. Treatment of symptomatic uterine fibroids with green tea extract: a pilot randomized controlled clinical study. Int J Womens Health. 2013;5:477–486.
  • Zhang D, Al-Hendy M, Richard-Davis G, et al. Antiproliferative and proapoptotic effects of epigallocatechin gallate on human leiomyoma cells. Fertil Steril. 2010;94(5):1887–1893.
  • Rosen R, Brown C, Heiman J, et al. The female sexual function index (FSFI): a multidimensional self-report instrument for the assessment of female sexual function. J Sex Marital Ther. 2000;26:191–208.
  • Donnez J, Hervais Vivancos B, Kudela M, et al. A randomized, placebo-controlled, dose-ranging trial comparing fulvestrant with goserelin in premenopausal patients with uterine fibroids awaiting hysterectomy. Fertil Steril. 2003;79(6):1380–1389.
  • Friedman AJ, Hoffman DI, Comite F, et al. Treatment of leiomyomata uteri with leuprolide acetate depot: a double-blind, placebo-controlled, multicenter study. The Leuprolide Study Group. Obstet Gynecol. 1991;77:720–725.
  • Donnez J, Tatarchuk TF, Bouchard P, et al. Ulipristal acetate versus placebo for fibroid treatment before surgery. N Engl J Med. 2012;366(5):409–420.
  • Al-Hendy A, Lukes AS, Poindexter AN, 3rd, et al. Treatment of uterine fibroid symptoms with relugolix combination therapy. N Engl J Med. 2021;384(7):630–642.
  • Elhusseini H, Elkafas H, Abdelaziz M, et al. Diet-induced vitamin D deficiency triggers inflammation and DNA damage profile in murine myometrium. Int J Womens Health. 2018; 10:503–514.
  • Toss A, Molinaro E, Sammarini M, et al. Hereditary ovarian cancers: state of the art. Minerva Med. 2019;110(4):301–319.
  • Ali M, Shahin SM, Sabri NA, et al. Hypovitaminosis D exacerbates the DNA damage load in human uterine fibroids, which is ameliorated by vitamin D3 treatment. Acta Pharmacol Sin. 2019;40(7):957–970.
  • Halder SK, Osteen KG, Al-Hendy A. Vitamin D3 inhibits expression and activities of matrix metalloproteinase-2 and -9 in human uterine fibroid cells. Hum Reprod. 2013;28(9):2407–2416.
  • Ciavattini A, Delli Carpini G, Serri M, et al. Hypovitaminosis D and “small burden” uterine fibroids: Opportunity for a vitamin D supplementation. Medicine (Baltimore). 2016;95(52):e5698.
  • Commandeur AE, Styer AK, Teixeira JM. Epidemiological and genetic clues for molecular mechanisms involved in uterine leiomyoma development and growth. Hum Reprod Update. 2015;21(5):593–615.
  • Allgood VE, Cidlowski JA. Vitamin B6 modulates transcriptional activation by multiple members of the steroid hormone receptor superfamily. J Biol Chem. 1992;267(6):3819–3824.
  • Wong JY, Gold EB, Johnson WO, et al. Circulating sex hormones and risk of uterine fibroids: study of women’s health across the nation (SWAN). J Clin Endocrinol Metab. 2016;101(1):123–130.

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