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Research Article

NOMAC-E2 compares to LNG combined oral contraceptives in women over forty: real-world PRO-E2 study

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Article: 2166032 | Received 08 Aug 2022, Accepted 03 Jan 2023, Published online: 23 Jan 2023

References

  • Harlow S D, Gass M, Hall JE, et al. Executive summary of the stages of reproductive aging workshop + 10: addressing the unfinished agenda of staging reproductive aging. Menopause. 2012;19(4):1–5.
  • Santoro N. Perimenopause: from research to practice. J Womens Health (Larchmt). 2016;25(4):332–339.
  • Shaaban MM. The perimenopause and contraception. Maturitas. 1996;23(2):181–192.
  • Kailas NA, Sifakis S, Koumantakis E. Contraception during perimenopause. Eur J Contracept Reprod Health Care. 2005;10(1):19–25.
  • Cho MK. Use of combined oral contraceptives in perimenopausal women. Chonnam Med J. 2018;54(3):153–158.
  • Davis A, Godwin A, Lippman J, et al. Triphasic norgestimate-ethinyl estradiol for treating dysfunctional uterine bleeding. Obstet Gynecol. 2000;96(6):913–920.
  • Fraser IS, McCarron G. Randomized trial of 2 hormonal and 2 prostaglandin-inhibiting agents in women with a complaint of menorrhagia. Aust N Z J Obstet Gynaecol. 1991;31(1):66–70.
  • Mendoza N, Soto E, Sánchez-Borrego R. Do women aged over 40 need different counseling on combined hormonal contraception? Maturitas. 2016;87:79–83.
  • Curtis KM, Tepper NK, Jatlaoui TC, et al. U.S. Medical Eligibility Criteria for contraceptive use. 2016 (July 29, 2016).
  • Faculty of Sexual & Reproductive Healthcare. FSRH Guideline Contraception for women aged over 40 years. August 2017. (Amended September 2019).
  • Ruan X, Seeger H, Mueck AO. The pharmacology of nomegestrol acetate. Maturitas. 2012;71(4):345–353.
  • European Medicines Agency. Guideline on good pharmacovigilance practices (GVP) – Module VIII – Post-authorisation safety studies (Rev. 3). 2017.
  • Reed S, Koro C, DiBello J, et al. Unintended pregnancy in users of nomegestrol acetate and 17β-oestradiol (NOMAC-E2) compared with levonorgestrel-containing combined oral contraceptives: final results from the PRO-E2 study. Eur J Contracept Reprod Health Care. 2021;26(6):447–453.
  • Reed S, Koro C, DiBello J, et al. Prospective controlled cohort study on the safety of a monophasic oral contraceptive containing nomegestrol acetate (2.5mg) and 17β-oestradiol (1.5mg) (PRO-E2 study): risk of venous and arterial thromboembolism. Eur J Contracept Reprod Health Care. 2021;26(6):439–446.
  • Arner P, Bernard S, Appelsved L, et al. Adipose lipid turnover and long-term changes in body weight. Nat Med. 2019;25(9):1385–1389.
  • Gebbie A. Contraception in the perimenopause. J Br Menopause Soc. 2003;9(3):123–128.
  • Klipping C, Duijkers I, Trummer D, et al. Suppression of ovarian activity with a drospirenone-containing oral contraceptive in a 24/4 regimen. Contraception. 2008;78(1):16–25.
  • Junge W, Mellinger U, Parke S, et al. Metabolic and haemostatic effects of estradiol valerate/dienogest, a novel oral contraceptive: a randomized, open-label, single-Centre study. Clin Drug Investig. 2011;31(8):573–584.
  • Fruzzetti F, Trémollieres F, Bitzer J. An overview of the development of combined oral contraceptives containing estradiol: focus on estradiol valerate/dienogest. Gynecol Endocrinol. 2012;28(5):400–408.
  • Susser M. What is a cause and how do we know one? A grammar for pragmatic epidemiology. Am J Epidemiol. 1991;133(7):635–648.
  • Read CM. New regimens with combined oral contraceptive pills–moving away from traditional 21/7 cycles. Eur J Contracept Reprod Health Care. 2010;15 Suppl 2: s 32–41.