36
Views
14
CrossRef citations to date
0
Altmetric
Original Article

A longitudinal evaluation of the effect of two doses of tibolone on bone density and metabolism in early postmenopausal women

, , , , , & show all
Pages 9-16 | Published online: 07 Jul 2009

References

  • World Health Organization. Assessment of Fracture Risk and its Application to Screening for Postmenopausal Osteoporosis. Geneva: WHO Technical Report Series 843.
  • Consensus Development Conference. Diagnosis, prophylaxis and treatment of osteoporosis. Am J Med 1993;94:646–50
  • Gambacciani M, Spinetti A, De Simone L, et al. The relative contributions of menopause and aging to postmenopausal vertebral osteopenia. J Clin Endocrinol Metab 1993;77:1148–51
  • Gambacciani M, Spinetti A, De Simone L, et al. Postmenopausal bone loss of the proximal femur: estimated contributions of menopause and aging. Menopause 1995;2:169–74
  • Gambacciani M, Spinetti A, Taponeco F, et al. Longitudinal evaluation of perimenopausal vertebral bone loss: effects of a low-dose oral contraceptive preparation on bone mineral density and metabolism. Obstet Gynecol 1994;83:392–6
  • Mosekilde L, Beck-Nielsen H, Sorensen OH, et al. Hormonal replacement therapy reduces forearm fracture incidence in recent postmenopausal women — results of the Danish Osteoporosis Prevention Study. Maturitas 2000;36:181–93
  • Torgerson DJ, Bell-Syer SE. Hormone replacement therapy and prevention of nonvertebral fractures: a meta-analysis of randomized trials. J Am Med Assoc 2001;285:2891–7
  • Tax L, Goorissen EM, Kicovic PM. Clinical profile of Org OD 14. Maturitas 1987;1: 3–13
  • Genazzani AR, Benedek-Jaszmann 14, Hart DM, et al. Org OD 14 and the endometrium. Maturitas 1991; 13:243–51
  • Moore RA Livial: a review of clinical studies. Br J Obstet Gynaecol 1999;106:1–21
  • Rymer J, Robinson J, Fogelman I, et al. Livial prevents postmenopausal bone loss — 8 years follow-up. Climacteric 1999;2:313
  • Bjarnason N, Bjarnason K, Haarbo J, et al. Tibolone: prevention of bone loss in late postmenopausal women. J Clin Endocrinol Metab 1996;81:2419–22
  • Berning B, Kuijk C, Kuiper J, et al. Effects of two doses of tibolone on trabecular and cortical bone loss in early postmenopausal women: a two-year randomized, placebo-controlled study. Bone 1996; 19:395–9
  • Greene JG. Constructing a standard climacteric scale. Maturitas 1998;29:25–31
  • Gambacciani M, Ciaponi M, Cappagli B, et al. Effects of low-dose, continuous combined conjugated estrogens and medroxyprogesterone acetate on menopausal symptoms, body weight, bone density and metabolism in postmenopausal women. Am J Obstet Gynecol 2001;185:1180–5
  • Wills M, Odegaard K, Persson U, et al. A cost-effectiveness model of tibolone as treatment for the prevention of osteoporotic fractures in postmeno-pausal women in Sweden. Clin Drug Invest 2001; 21:115–27
  • Sins ES, Miller PD, Barrett-Connor E, et al. Identification and fracture outcomes of undiagnosed low bone mineral density in postmenopausal women: results from the National Osteoporosis Risk Assessment. J Am Med Assoc 2001;286:2815-22, 2865–6
  • Gallagher JC, Baylink DJ, Freeman R, et al. Prevention of bone loss with tibolone in postmeno-pausal women: results of two randomized, double-blind, placebo-controlled, dose-finding studies. J Clin Endocrinol Metab 2001;86:4717–26
  • Melton 14 III, Atkinson EJ, O'Fallon WM, et al. Long-term fracture prediction by bone mineral assessed at different skeletal sites. J Bone Miner Res 1993;8:1227–33
  • Wasnich RD, Miller PD. Antifracture efficacy of antiresorptive agents are related to changes in bone density. J Clin Endocrinol Metab 2000;85:231–6
  • Cauley JA, Zmuda JM, Ensrud KE, et al. Timing of estrogen replacement therapy for optimal osteo-porosis prevention. J Clin Endocrinol Metab 2001; 86:5700–5

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.