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Original

Ovariectomy exacerbates oxidative stress and cardiopathyinduced by adriamycin

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Pages 74-79 | Received 29 Apr 2005, Accepted 24 Nov 2005, Published online: 26 Aug 2009

References

  • Dimitrova K R, DeGroot K, Myers A K, Kim Y D. Estrogen and homocysteine. Cardiovasc Res 2002; 53: 577–588
  • Zhu W, Everson W V, Smart E J. Estrogen in cardiovascular disease. Curr Opin Lipidol 2004; 15: 589–593
  • Rosano G M, Vitale C, Silvestri A, Fini M. Metabolic and vascular effect of progestins in post-menopausal women. Implications for cardioprotection. Maturitas 2003; 10: S17–S29
  • Collins P. Clinical cardiovascular studies of hormone replacement therapy. Am J Cardiol 2002; 90: 30–34
  • Ganz P. Vasomotor and vascular effects of hormone replacement therapy. Am J Cardiol 2002; 90: 11–16
  • Solerte S B, Fioravanti M, Racchi M, Trabucchi M, Zanetti O, Govoni S. Menopause and estrogen deficiency as a risk factor in dementing illness: hypothesis on the biological basis. Maturitas 1999; 31: 95–101
  • van der Schouw Y T, van der Graaf Y, Steyerberg E W, Eijkemans J C, Banga J D. Age at menopause as a risk factor for cardiovascular mortality. Lancet 1996; 347: 714–718
  • Scorza R, Caronni M, Bazzi S, Nador F, Beretta L, Antonioli R, Origgi L, Ponti A, Marchini M, Vanoli M. Post-menopause is the main risk factor for developing isolated pulmonary hypertension in systemic sclerosis. Ann N Y Acad Sci 2002; 966: 238–246
  • Gohlke-Barwolf C. Coronary artery disease – is menopause a risk factor?. Basic Res Cardiol 2000; 95: I77–I83
  • Sitruk-Ware R, Ibarra de Palacios O. Oestrogen replacement therapy and cardiovascular disease in postmenopausal women. Maturitas 1989; 11: 259–274
  • Bednarek-Tupikowska G, Tupikowski K, Bidzinska B, Bohdanowicz-Pawlak A, Antonowicz-Juchniewicz J, Kosowska B, Milewicz A. Serum lipid peroxides and total antioxidant status in postmenopausal women on hormone replacement therapy. Gynecol Endocrinol 2004; 19: 57–63
  • Montilla P, Túnez I, Muñoz M C, Delgado M J, Salcedo M. Hyperlipidemic nephropathic induced by adriamycin in ovariectomized rats: role of free radicals and effects of 17β estradiol administration. Nephron 2000; 85: 65–70
  • Hernández I, Delgado J L, Díaz J, Quesada T G, Teruel M J, Llanos M C, Carbonell L F. 17β Estradiol prevents oxidative stress and decreases blood pressure in ovariectomized rats. Am J Physiol Regulatory Integr Comp Physiol 2000; 79: R1599–R1605
  • Persky A M, Green P S, Stubley L, Howell C O, Zaulyanov L, Brazeau G A, Simpkins J W. Protective effect of estrogens against oxidative damage to heart and skeletal muscle in vivo and in vitro. Proc Soc Exp Biol Med 2000; 223: 59–66
  • Ha B J. Oxidative stress in ovariectomy menopause and role of chondroitin sulfate. Arch Pharm Res 2004; 27: 867–872
  • Gewirtz D A. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem Pharmacol 1999; 57: 727–741
  • Quiles J L, Huertas J R, Battino M, Mataix J, Ramírez-Tortosa M C. Antioxidant nutrients and adriamycin toxicity. Toxicology 2002; 180: 79–95
  • Singal P K, Pierce G N. Adriamycin stimulates low-affinity Ca2+ binding and lipid peroxidation but depresses myocardial function. Am J Physiol 1986; 250: 419–425
  • Sokolove P M, Kester M B, Haynes J. Interaction of adriamycin aglycones with isolated mitochondria. Effect of selenium deficiency. Biochem Pharmacol 1993; 46: 691–697
  • Singal P K, Li T, Kumar D, Danelisen I, Iliskovic N. Adriamycin-induced heart failure: mechanism and modulation. Mol Cell Biochem 2000; 207: 77–85
  • Singal P K, Iliskovic N. Doxorubicin-induced cardiomyopathy. N Engl J Med 1998; 339: 900–905
  • Siveski-Iliskovic N, Hill M, Chow D A, Singal P K. Probucol protects against adriamycin cardiomyopathy without interfering with its antitumor effect. Circulation 1995; 91: 10–15
  • Poumeau-Delille G. Techniques biologiques en endocrinologie experimentale chez rat. Masson and Cie, ParisFrance 1953
  • Oliver C N, Ahn B W, Moerman E J, Goldstein S, Stadtman E R. Age-related changes in oxidized proteins. J Biol Chem 1987; 262: 5488–5491
  • Flohé L, Gunzler W A. Assays of glutathione peroxidase. Methods Enzymol 1984; 105: 114–121
  • Aebi H. Catalase in vitro. Methods Enzymol 1984; 105: 121–126
  • Sun Y, Oberley L W, Li Y. A simple method for clinical assay of superoxide dismutase. Clin Chem 1988; 34: 479–500
  • Goormaghtigh E, Ruysschaert J M. Anthracycline glycoside–membrane interactions. Biochim Biophys Acta 1984; 779: 271–288
  • Cullinane C, Cutts S M, van Rosmalen A, Phillips D R. Does adriamycin induce interstrand cross-links in DNA?. Nucleic Acids Res 1994; 22: 2296–2303
  • Skladanowski A, Konopa J. Interstrand DNA crosslinking induced by anthracyclines in tumour cells. Biochem Pharmacol 1994; 47: 2269–2278
  • Tanaka M, Yoshida S. Expression of stress response and cell proliferation genes in renal cell carcinoma induced by oxidative stress. J Biochem 1980; 87: 911–918
  • Kastan M B, Onyekwere O, Sidransky D, Vogelstein B, Craig R W. Participation of p53 protein in the cellular response to DNA damage. Cancer Res 1991; 51: 6304–6311
  • Olson R D, Mushlin P S. Doxorubicin cardiotoxicity: analysis of prevailing hypotheses. FASEB J 1990; 4: 3076–3086
  • Misiti F, Giardina B, Mordente A, Clementi M E. The secondary alcohol and aglycones metabolites of doxorubicin alter metabolism of human erythrocytes. Braz J Med Biol Res 2003; 36: 1643–1651
  • Clementi M E, Giardina B, Di Stasio E, Mordente A, Misiti F. Doxorubicin-derived metabolites induce release of cytochrome C and inhibition of respiration on cardiac isolated mitochondria. Anticancer Res 2003; 23: 2445–2450
  • Rice-Evans C, Baysal E. Iron-mediated oxidative stress in erythrocytes. Biochem J 1987; 244: 191–196
  • Strehlow K, Rotter S, Wassmann S, Adam O, Grohé C, Laufs K, Böhm M, Nickenig G. Modulation of antioxidant enzyme expression and function by estrogen. Circ Res 2003; 93: 170–177
  • Pajovic S B, Saiciz Z S, Spasic M B, Petrovic V M, Martinovic J V. Effects of progesterone and estradiol benzoate on glutathione dependent antioxidant enzyme activities in the brain of female rats. Gen Physiol Biophys 1999; 18: 35–44
  • Ozgonul M, Oge A, Sezer E D, Bayraktar F, Sozmen E Y. The effects of estrogen and raloxifene treatment on antioxidant enzymes in brain and liver of ovariectomized female rats. Endocr Res 2003; 29: 183–189
  • Simoncini T, Fornari L, Mannella P, Varone G, Caruso A, Liao J K, Genazzani A R. Novel non-transcriptional mechanisms for estrogen receptor signalling in the cardiovascular system. Interaction of estrogen receptor α with phosphatidylinositol 3-OH kinase. Steroids 2002; 67: 935–939
  • Lutosławska G, Tkaczyk J, Panczenko-Kresowska B, Hübner-Woźniaka E, Skierskab E, Gajewski A K. Plasma TBARS, blood GSH concentrations, and erythrocyte antioxidant enzyme activities in regularly menstruating women with ovulatory and anovulatory menstrual cycles. Clin Chim Acta 2003; 331: 159–163
  • Chao T, Alten P V, Walter R J. Steroid sex hormones and macrophages function. Modulation of reactive oxygen intermediates and nitrite release. Am J Reprod Immunol 1994; 32: 43–52
  • Prediger M E, Siqueira I R, Gamaro G D, Silva M S, Netto C A, Dalmaz C. Protective effect of pregnalone against lipoperoxidation and free radicals generation induced in hypothalamus of ovariectomized rats submitted to CO2 exposure. Pharmacol Biochem Behav 2004; 78: 191–197
  • Proteggente A R, England T G, Rehman A, Rice-Evans C A, Halliwell B. Gender differences in steady-state levels of oxidative damage to DNA in healthy individuals. Free Radic Res 2002; 36: 157–162
  • Lacy F, Kailasam M T, O'Connor D T, Schmid-Schonbein G W, Parmer R J. Plasma hydrogen peroxide production in human essential hypertension: role of heredity, gender, and ethnicity. Hypertension 2000; 36: 878–884
  • Aragno M, Paola S, Tamagno E, Brignardello E, Manti R, Danni O, Boccuzzi G. Oxidative derangement in rat synaptosomes induced by hyperglycaemia: restorative effect of dehydroepiandrosterone treatment. Biochem Pharmacol 2000; 60: 389–395
  • Wassmann S, Bäumer A T, Strehlow K, van Eickels M, Grohé C, Ahlbory K, Rösen R, Böhm M, Nickening G. Endothelial dysfunction and oxidative stress during estrogen deficiency in spontaneously hypertensive rats. Circulation 2001; 103: 435–441
  • Zhai P, Eurell T E, Cotthaus R, Jeffery E H, Bahr J M, Gross D R. Effect of estrogen on global myocardial ischemia–reperfusion injury in female rats. Am J Physiol Heart Circ Physiol 2000; 279: H2766–H2775
  • Kauser K, Rubanyi G M. Potential cellular signalling mechanisms mediating upregulation of endothelial nitric oxide production by estrogen. J Vasc Res 1997; 34: 229–236
  • Virdis A, Ghiadoni L, Pinto S, Lombardo M, Petraglia F, Gennazzani A, Buralli S, Tadei S, Salvetti A. Mechanisms responsible for endothelial dysfunction associated with acute estrogen deprivation in normotensive women. Circulation 2000; 101: 2258–2263
  • Wade G N. Gonadal hormones and behavioral regulation of body weight. Physiol Behav 1972; 8: 523–534
  • Wade G N, Zucker Y. Taste preferences of female rats: modification by neonatal hormones, food deprivation and prior experience. Physiol Behav 1969; 4: 935–943
  • Geary N, Asarian L. Cyclic estradiol treatment normalizes body weight and test meal size in ovariectomized rats. Physiol Behav 1999; 67: 141–147

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