Effects of oral continuous 17β-estradiol plus norethisterone acetate replacement therapy on abdominal subcutaneous fat, serum leptin levels and body composition

References

• American Heart Association. Heart disease and stroke statistics – 2003 update. American Heart Association, Dallas, TX 2002
   Google Scholar
• Writing Group for the PEPI Trial. Effects of estrogen or estrogen/progestin regimens on heart disease risk factors in postmenopausal women. The Postmenopausal Estrogen/ Progestin Interventions (PEPI) Trial. J Am Med Assoc 1995; 273: 199–208
   PubMed Web of Science ®Google Scholar
• Gambacciani M, Ciaponi M, Cappagli B, De Simone L, Orlandi R, Genazzani A R. Prospective evaluation of body weight and body fat distribution in early postmenopausal women with and without hormonal replacement therapy. Maturitas 2001; 39: 125–132
   PubMed Web of Science ®Google Scholar
• Guthrie J R, Dennerstein L, Taffe J R, Lehert P, Burger H G. The menopausal transition: a 9-year prospective population-based study. The Melbourne Women's Midlife Health Project. Climacteric 2004; 7: 375–389
   PubMed Web of Science ®Google Scholar
• Rossouw J E, Anderson G L, Prentice R L, LaCroix A Z, Kooperberg C, Stefanick M L, Jackson R D, Beresford S A, Howard B V, Johnson K C. Writing Group for the Women's Health Initiative Investigators. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. J Am Med Assoc 2002; 288: 321–333
   PubMed Web of Science ®Google Scholar
• Norman R J, Flight I H, Rees M C. Oestrogen and progestogen hormone replacement therapy for peri-menopausal and post-menopausal women: weight and body fat distribution. Cochrane Database Syst Rev 2000, 2, CD001018
   PubMedGoogle Scholar
• Samaras K, Hayward C S, Sullivan D, Kelly R P, Campbell L V. Effects of postmenopausal hormone replacement therapy on central abdominal fat, glycemic control, lipid metabolism, and vascular factors in type 2 diabetes: a prospective study. Diabetes Care 1999; 22: 1401–1407
   PubMed Web of Science ®Google Scholar
• Machens K, Schmidt-Gollwitzer K. Issues to debate on the Women's Health Initiative (WHI) study. Hormone replacement therapy: an epidemiological dilemma?. Hum Reprod 2003; 18: 1992–1929
   PubMedGoogle Scholar
• Friedman J M, Halaas J L. Leptin and the regulation of body weight in mammals. Nature 1998; 395: 763–770
   PubMed Web of Science ®Google Scholar
• Minocci A, Savia G, Lucantoni R, Berselli M E, Tagliaferri M, Calo G, Petroni M L, de Medici C, Viberti G C, Liuzzi A. Leptin plasma concentrations are dependent on body fat distribution in obese patients. Int J Obes Relat Metab Disord 2000; 24: 1139–1144
   PubMed Web of Science ®Google Scholar
• Van Harmelen V, Reynisdottir S, Eriksson P, Thorne A, Hoffstedt J, Lonnqvist F, Arner P. Leptin secretion from subcutaneous and visceral adipose tissue in women. Diabetes 1998; 47: 913–917
   PubMed Web of Science ®Google Scholar
• Kohrt W M, Landt M, Birge S J, Jr. Serum leptin levels are reduced in response to exercise training, but not hormone replacement therapy, in older women. J Clin Endocrinol Metab 1996; 81: 3980–3985
   PubMed Web of Science ®Google Scholar
• Rosenbaum M, Nicolson M, Hirsch J, Heymsfield S B, Gallagher D, Chu F, Leibel R L. Effects of gender, body composition, and menopause on plasma concentrations of leptin. J Clin Endocrinol Metab 1996; 81: 3424–3427
   PubMed Web of Science ®Google Scholar
• Shimizu H, Shimomura Y, Nakanishi Y, Futawatari T, Ohtani K, Sato N, Mori M. Estrogen increases in vivo leptin production in rats and human subjects. J Endocrinol 1997; 154: 285–292
   PubMed Web of Science ®Google Scholar
• Yoneda N, Saito S, Kimura M, Yamada M, Iida M, Murakami T, Irahara M, Shima K, Aono T. The influence of ovariectomy on ob gene expression in rats. Horm Metab Res 1998; 30: 263–265
   PubMed Web of Science ®Google Scholar
• Messinis I E, Milingos S, Zikopoulos K, Kollios G, Seferiadis K, Lolis D. Leptin concentrations in the follicular phase of spontaneous cycles and cycles superovulated with follicle stimulating hormone. Hum Reprod 1998; 13: 1152–1156
   PubMed Web of Science ®Google Scholar
• Havel P J, Kasim-Karakas S, Dubuc G R, Mueller W, Phinney S D. Gender differences in plasma leptin concentrations. Nat Med 1996; 2: 949–950
   PubMed Web of Science ®Google Scholar
• Arabi A, Garnero P, Porcher R, Pelissier C, Benhamou C L, Roux C. Changes in body composition during post- menopausal hormone therapy: a 2 year prospective study. Hum Reprod 2003; 18: 1747–1752
   PubMed Web of Science ®Google Scholar
• Kristensen K, Pedersen S B, Vestergaard P, Mosekilde L, Richelsen B. Hormone replacement therapy affects body composition and leptin differently in obese and non-obese postmenopausal women. J Endocrinol 1999; 163: 55–62
   PubMed Web of Science ®Google Scholar
• Laivuori H, Koistinen H A, Karonen S L, Cacciatore B, Ylikorkala O. Comparison between 1 year oral and transdermal oestradiol and sequential norethisterone acetate on circulating concentrations of leptin in postmenopausal women. Hum Reprod 2001; 16: 1632–1635
   PubMedGoogle Scholar
• Walker R J, Lewis-Barned N J, Sutherland W H, Goulding A, Edwards E A, de Jong S A, Gold E, Walker H L. The effects of sequential combined oral 17β-estradiol norethisterone acetate on insulin sensitivity and body composition in healthy postmenopausal women: a randomized single blind placebo-controlled study. Menopause 2001; 8: 27–32
   PubMed Web of Science ®Google Scholar
• Coope J, Marsh J. Can we improve compliance with long-term HRT?. Maturitas 1992; 15: 151–158
   PubMed Web of Science ®Google Scholar
• World Health Organization. Measuring obesity – classification and description of anthropometric data. WHO Regional Office for Europe, Copenhagen 1988, EUR/ICP/NUT 125-0612. V
   Google Scholar
• Pouliot M C, Despres J P, Lemieux S, Moorjani S, Bouchard C, Tremblay A, Nadeau A, Lupien P J. Waist circumference and abdominal sagittal diameter: best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women. Am J Cardiol 1994; 73: 460–468
   PubMed Web of Science ®Google Scholar
• Janssen I, Katzmarzyk P T, Ross R. Waist circumference and not body mass index explains obesity-related health risk. Am J Clin Nutr 2004; 79: 379–384
   PubMed Web of Science ®Google Scholar
• Gruber C J, Wieser F, Gruber I M, Ferlitsch K, Gruber D M, Huber J C. Current concepts in aesthetic endocrinology. Gynecol Endocrinol 2002; 16: 431–441
   PubMed Web of Science ®Google Scholar
• Hardie L, Trayhurn P, Abramovich D, Fowler P. Circulating leptin in women: a longitudinal study in the menstrual cycle and during pregnancy. Clin Endocrinol (Oxf) 1997; 47: 101–106
   PubMed Web of Science ®Google Scholar
• Messinis I E, Kariotis I, Milingos S, Kollios G, Seferiadis K. Treatment of normal women with oestradiol plus progesterone prevents the decrease of leptin concentrations induced by ovariectomy. Hum Reprod 2000; 15: 2383–2387
   PubMed Web of Science ®Google Scholar
• Pedersen S B, Fuglsig S, Sjogren P, Richelsen B. Identification of steroid receptors in human adipose tissue. Eur J Clin Invest 1996; 26: 1051–1056
   PubMed Web of Science ®Google Scholar
• O'Brien S N, Welter B H, Mantzke K A, Price T M. Identification of progesterone receptor in human subcutaneous adipose tissue. J Clin Endocrinol Metab 1998; 83: 509–513
   PubMed Web of Science ®Google Scholar
• Thomas T, Burguera B, Melton L J, 3rd, Atkinson E J, O'Fallon W M, Riggs B L, Khosla S. Relationship of serum leptin levels with body composition and sex steroid and insulin levels in men and women. Metabolism 2000; 49: 1278–1284
   PubMed Web of Science ®Google Scholar
• Wauters M, Mertens I, Considine R, De Leeuw I, Van Gaal L. Are leptin levels dependent on body fat distribution in obese men and women?. Eat Weight Disord 1998; 3: 124–130
   PubMedGoogle Scholar
• Armellini F, Zamboni M, Rigo L, Bergamo-Andreis I A, Robbi R, De Marchi M, Bosello O. Sonography detection of small intra-abdominal fat variations. Int J Obes 1991; 15: 847–852
   PubMed Web of Science ®Google Scholar
• Lapidus L, Bengtsson C, Larsson B, Pennert K, Rybo E, Sjostrom L. Distribution of adipose tissue and risk of cardiovascular disease and death: a 12 year follow up of participants in the population study of women in Gothenburg, Sweden. Br Med J (Clin Res Ed) 1984; 289: 1257–12561
   PubMed Web of Science ®Google Scholar
• Pontiroli A E, Pizzocri P, Giacomelli M, Marchi M, Vedani P, Cucchi E, Orena C, Folli F, Paganelli M, Ferla G. Ultrasound measurement of visceral and subcutaneous fat in morbidly obese patients before and after laparoscopic adjustable gastric banding: comparison with computerized tomography and with anthropometric measurements. Obes Surg 2002; 12: 648–651
   PubMedGoogle Scholar
• Isidori A M, Strollo F, More M, Caprio M, Aversa A, Moretti C, Frajese G, Riondino G, Fabbri A. Leptin and aging: correlation with endocrine changes in male and female healthy adult populations of different body weights. J Clin Endocrinol Metab 2000; 85: 1954–1962
   PubMed Web of Science ®Google Scholar
• Janssen I, Heymsfield S B, Allison D B, Kotler D P, Ross R. Body mass index and waist circumference independently contribute to the prediction of nonabdominal, abdominal subcutaneous, and visceral fat. Am J Clin Nutr 2002; 75: 683–688
   PubMed Web of Science ®Google Scholar