51
Views
2
CrossRef citations to date
0
Altmetric
Original

Effects of intranasal 17β-estradiol and raloxifene on lipid profile and fibrinogen in hypercholesterolemic postmenopausal women: A randomized, placebo-controlled clinical trial

, , &
Pages 676-679 | Received 23 May 2006, Accepted 16 Oct 2006, Published online: 07 Jul 2009

References

  • Woodward M, Rumley A, Tunstall-Pedoe H, Lowe G DO. Associations of blood rheology and interleukin-6 with cardiovascular risk factors and prevalent cardiovascular disease. Br J Haematol 1999; 104: 246–257
  • Stamler J, Daviglus M L, Garside D B, Dyer A R, Greenland P, Neaton J D. Relationship of baseline serum cholesterol levels in three large cohorts of younger men to long-term coronary, cardiovascular, and all-cause mortality and to longevity. J Am Med Assoc 2000; 284: 311–318
  • Darling G M, Johns J A, McCloud P I, Davis S R. Estrogen and progestin compared with simvastatin for hypercholesterolemia in postmenopausal women. N Engl J Med 1997; 337: 595–601
  • Davidson M H, Testolin L M, Maki K C, von Duvillard S, Drennan K B. A comparison of estrogen replacement, pravastatin, and combined treatment for the management of hypercholesterolemia in postmenopausal women. Arch Intern Med 1997; 157: 1186–1192
  • Hulley S, Grady D, Bush T, Furberg C, Herrington D, Riggs B, Vittinghoff E. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. J Am Med Assoc 1998; 280: 605–613
  • Ridker P, Stampfer M J, Rifai N. Novel risk factors for systemic atherosclerosis: a comparison of C-reactive protein, fibrinogen, homocysteine, lipoprotein(a), and standard cholesterol screening as predictors of peripheral artery disease. J Am Med Assoc 2001; 285: 2481–2507
  • Devissaguet J P, Brion N, Lhote O, Deloffre P. Pulsed estrogen therapy: pharmacokinetics of intranasal 17β-estradiol (intranasal oestradiol) in postmenopausal women and comparison with oral and transdermal formulations. Eur J Drug Metab Pharmacokinet 1999; 24: 265–271
  • Kauffman R F, Bryant H U. Selective estrogen receptor modulators. Drugs New Perspect 1995; 8: 531–539
  • Lakoski S G, Herrington D M. Effects of estrogen receptor-active compounds on lipid metabolism. Diabetes Obes Metab 2005; 7: 471–477
  • Walsh B W, Paul S, Wild R A. The effects of hormone replacement therapy and raloxifene on C-reactive protein and homocysteine in healthy postmenopausal women: a randomized, controlled trial. J Clin Endocrinol Metab 2000; 85: 214–218
  • Dias A R, Jr, Melo R N, Gebara O C, D'Amico E A, Nussbacher A, Halbe H W, Pinotti J A. Effects of conjugated equine estrogens or raloxifene on lipid profile, coagulation and fibrinolysis factors in postmenopausal women. Climacteric 2005; 8: 63–70
  • Basurto L, Saucedo R, Zarate A, Martinez C, Gaminio E, Reyes E, Hernandez M. Effect of pulsed estrogen therapy on hemostatic markers in comparison with oral estrogen regimen in postmenopausal women. Gynecol Obstet Invest 2006; 61: 61–64
  • Insull W, Jr, Davidson M H, Kulkarni P M, Siddhanti S, Ciaccia A V, Keech C A. Effects of raloxifene and low-dose simvastatin coadministration on plasma lipids in postmenopausal women with primary hypercholesterolemia. Metabolism 2005; 54: 939–946

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.