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Original

Low leptin level in an obese hyperandrogenic woman – potential marker for androgen-secreting tumor

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Pages 112-116 | Received 08 Jun 2006, Accepted 05 Jan 2007, Published online: 07 Jul 2009

References

  • Kaltsas G A, Mukherjee J J, Kola B, Isidori A M, Hanson J A, Dacie J E, Reznek R, Monson P, Grossman A B. Is ovarian and adrenal catheterization and sampling helpful in the investigation of hyperandrogenic women?. Clin Endocrinol (Oxf) 2003; 59: 34–43
  • Loh K C, Lo J C, Zaloudek C J, Fitzgerald P A. Occult virilizing ovarian tumors in postmenopausal women: problems in evaluation with reference to a case. Ann Acad Med Singapore 1988; 27: 712–716
  • Ryan J J, Rezkalla M A, Rizk S N, Peterson K G, Wiebe R H. Testosterone-secreting adrenal adenoma that contained crystalloids of Reinke in an adult female patient. Mayo Clin Proc 1995; 70: 380–383
  • Goodarzi M O, Dawson D W, Li X, Lei Z, Shintaku P, Rao C V, Van Herle A J. Virilization in bilateral macronodular adrenal hyperplasia controlled by luteinizing hormone. J Clin Endocrinol Metab 2003; 88: 73–77
  • Loszio F A, Toth S, Kocsis J, Pavo J, Szecsi M. Testosterone-secreting gonadotropin-responsive adrenal adenoma and its treatment with antiandrogen flutamide. J Endocrinol Invest 2001; 24: 622–627
  • Marcondes J A, Nery M, Mendonca B B, Hayashida S A, Halbe H W, Carvalho F M, Wajchenberg B L. A virilizing Leydig cell tumor of the ovary associated with stromal hyperplasia under gonadotropin control. J Endocrinol Invest 1997; 20: 685–689
  • Bricaire C, Raynaud A, Benotmane A, Clair F, Paniel B, Mowszowicz I, Wright F, Moreau J F, Kuttenn F, Mauvais-Jarvis P. Selective venous catheterization in the evaluation of hyperandrogenism. J Endocrinol Invest 1991; 14: 949–956
  • Regnier C, Bennet A, Malet D, Guez T, Plantavid M, Rochaix P, Monrozies X, Louvet J P, Caron P. Intraoperative testosterone assay for virilizing ovarian tumor topographic assessment: report of a Leydig cell tumor of the ovary in a premenopausal woman with an adrenal incidentaloma. J Clin Endocrinol Metab 2002; 87: 3074–3077
  • Gorgojo J J, Almodovar F, Lopez E, del Cerro J V, Tejerina E, Donnay S. Coincidental diagnosis of an occult hilar steroid cell tumor of the ovary and a cortisol-secreting adrenal adenoma in a 49-year-old woman with severe hyperandrogenism. Fertil Steril 2003; 80: 1504–1507
  • Micic D, Sumarac-Dumanovic M, Macut D J, Kendereski A, Zoric S, Popovic V, Cvijovic G, Dieguey C, Casanueva F F. Growth-hormone response to combined stimulation with GHRH plus GH-releasing peptide-6 in obese patients with polycystic ovary syndrome before and after short-term fasting. J Endocrinol Invest 2003; 26: 333–340
  • Pekic S, Vujovic S, Spremovic-Radjenovic S, Petakov M, Djurovic M, Damjanovic S, Micic D, Dieguez C, Casanueva F F, Popovic V. Loss of gender difference in serum leptin levels and its slow recovery after successful surgery for Leydig cell tumours in two virilized females. Clin Endocrinol (Oxf) 2001; 54: 693–697
  • Sciarra F, Tosti-Croce C, Toscano V. Androgen-secreting adrenal tumors. Minerva Endocrinol 1995; 20: 63–68
  • Outwater E K, Marchetto B, Wagner B J. Virilizing tumors of the ovary: imaging features. Ultrasound Obstet Gynecol 2000; 15: 365–371
  • Wang P H, Chao H T, Liu R S, Cho Y-H, Ng H-T, Yuan C-C. Diagnosis and localization of testosterone-producing ovarian tumors: imaging or biochemical evaluation. Gynecol Oncol 2001; 83: 596–598
  • Stephens J W, Katz J R, McDermott N, MacLean A B, Bouloux P M. An unusual steroid-producing ovarian tumour: case report. Hum Reprod 2002; 17: 1468–1471
  • Cohen I, Cuperman S, Altaras M M, Ben-Nun I, Goldberg E, Beyth Y. Combined ovarian vein catheterization with ovarian stimulation in the diagnosis of androgen overproduction. Acta Obstet Gynecol Scand 1992; 71: 245–248
  • White L C, Buchanan K D, O'Leary T D, Carlan S J, Boothby R. Direct laparoscopic venous sampling to diagnose a small Sertoli–Leydig tumor. Gynecol Oncol 2003; 91: 254–257
  • Micic D, Macut D J, Popovic V, Sumarac-Dumanovic M, Kendereski A, Colic M, Dieguez C, Casanueva F F. Leptin levels and insulin sensitivity in obese and non-obese patients with polycystic ovary syndrome. Gynecol Endocrinol 1997; 11: 315–320
  • Popovic V, Micic D, Petakov M. Testosterone does not affect leptin secretion by adipocytes in vivo and in vitro evidence. Proceedings of the 80th Meeting of the Endocrine Society, New Orleans, LA, 1998, 2/536
  • Macut D J, Micic D, Zoric S, Sumarac M, Kendereski A, Cvijovic G, Casanueva F F, Zubieta J C, Sullivan K M, Smith D C. Decrease of serum leptin levels in adult male with idiopathic hypogonadotrophic hypogonadism (IHH) treated with pulsatile gonadotropin-releasing hormone (GnRH). J Endocrinol Invest 2001; 24: 135–136

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