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Editorial

Progesterone and progesterone receptor modulator in uterine leiomyoma growth

Pages 186-187 | Published online: 07 Jul 2009

References

  • Maruo T, Matsuo H, Gao Z, Spitz I M, Johansson E. Effects of progesterone on uterine leiomyoma growth and apoptosis. Steroids 2000; 65: 585–592
  • Maruo T, Laoag-Fernandez J B, Pakarinen P, Spitz I M, Johansson E. Effects of levonorgestrel-releasing intrauterine system on the endometrium and the relevance to the management of menorrhagia caused by uterine myoma and adenomyosis. Cell and molecular biology of endometrium in health and disease, T Maruo, D Barlow, H Mardon, S Kennedy. Soeisha, Osaka 2002; 193–207
  • Maruo T, Laoag-Fernandez J B, Spitz I M, Johansson E. Effects of the levonorgestrel-releasing intrauterine system on proliferation and apoptosis in the endometrium. Hum Reprod 2001; 16: 2103–2108
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  • Gao Z, Matsuo H, Nakago S, Maruo T. Up-regulation by IGF-I of proliferating cell nuclear antigen and Bcl-2 protein expression in human uterine leiomyoma cells. J Clin Endocrinol Metab 2001; 86: 5593–5599
  • Shimomura Y, Matsuo H, Samoto T, Maruo T. Up-regulation by progesterone of proliferating cell number antigen and epidermal growth factor expression in human uterine leiomyoma. J Clin Endocrinol Metab 1998; 83: 2192–2198
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  • Yamada T, Nakago S, Matsuo H, Maruo T. Progesterone down-regulates insulin-like growth factor-I expression in cultured human uterine leiomyoma cells. Hum Reprod 2004; 19: 1–7
  • Maruo T, Ohara N, Wang J, Matsuo H. Sex steroidal regulation of uterine leiomyoma growth and apoptosis. Hum Reprod Update 2004; 10: 207–220
  • Maruo T, Matsuo H, Yamada T, Kurachi O, Gao Z, Nakago S, Yamada T, Chen W, Wang J. Effects of progesterone on growth factor expression in human uterine leiomyoma. Steroids 2003; 68: 817–824
  • Xu Q, Ohara N, Sitruk-Ware R, Johansson E DB, Maruo T. Progesterone receptor modulator CDB-2914 down-regulates proliferative cell nuclear antigen and Bcl-2 protein expression and up-regulates caspase-3 and (adenosine 5′-diphosphate-ribose) polymerase expression in cultured human uterine leiomyoma cells. J Clin Endocrinol Metab 2005; 90: 953–961
  • Xu Q, Ohara N, Maruo T, Liu J, Sasaki H, Morikawa A, Sitruk-Ware R, Johansson E D, Maruo T. Progesterone receptor modulator CDB2914 down-regulates VEGF, adrenomedullin and their receptors and modulates progesterone receptor content in cultured human uterine leiomyoma cells. Hum Reprod 2006; 21: 2408–2416

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