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Case Study

Effect of combined administration of clopidogrel and lysine acetylsalicylate versus clopidogrel and aspirin on platelet aggregation and activated GPIIb/IIIa expression in healthy volunteers

, PhD , M.D., , , , , , , & show all
Pages 105-107 | Received 09 Sep 2005, Published online: 07 Jul 2009

References

  • Antithrombotic Trialists’ Collaboration. Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients. Br Med J 2002; 324: 71–86
  • Steinhubl SR, Berger PB, Mann JT, Fry ETA, DeLago A, Wilmer C, et al. Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention; a randomized controlled trial. J Am Med Assoc 2002; 288: 2411–2420
  • Bretagne JF, Feulli A, Gosselin M, Gastard J. Aspirin and gastroduodenal toxicity. A double blind endoscopic study of the effects of placebo, aspirin and lysine acetylsalicylate in healthy subjects. Gastroenterol Clin Biol 1984; 8: 28–32
  • The CURE Trial Investigators. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndrome without ST elevation. New Engl J Med 2001; 345: 494–502
  • Serebruany VL, Malinin AI, Jerome SD, Lowry DR, Morgan AW, Sane DC, et al. Effects of clopidogrel and aspirin combination versus aspirin alone on platelet aggregation and major receptor expression in patients with heart failure: The plavix use for treatment of congestive heart failure (PLUTO-CHF) trial. Am Heart J 2003; 146: 713–720

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