Advanced search
Publication Cover
Platelets Volume 17, 2006 - Issue 6
Submit an article Journal homepage
47
Views
3
CrossRef citations to date
0
Altmetric
Original article

Do heterotrimeric G proteins redistribute upon G protein-coupled receptor stimulation in platelets?

Bryan N. Kahner Department of Physiology and the Sol Sherry Thrombosis Research Center, Temple University School of Medicine, Philadelphia, PA 19140, USA
,
Todd M. Quinton Department of Physiology and the Sol Sherry Thrombosis Research Center, Temple University School of Medicine, Philadelphia, PA 19140, USA
,
Sarah Langan Department of Physiology and the Sol Sherry Thrombosis Research Center, Temple University School of Medicine, Philadelphia, PA 19140, USA
&
Satya P. Kunapuli PhD Department of Physiology and the Sol Sherry Thrombosis Research Center, Temple University School of Medicine, Philadelphia, PA 19140, USACorrespondence[email protected]
Pages 397-404 | Received 14 Feb 2006, Accepted 20 Jun 2006, Published online: 07 Jul 2009

References

  • Hepler JR, Gilman AG. G proteins. Trends Biochem Sci 1992; 17(10)383–387
  • Neer EJ. Heterotrimeric G proteins: Organizers of transmembrane signals. Cell 1995; 80(2)249–257
  • Offermanns S. The role of heterotrimeric G proteins in platelet activation. Biol Chem 2000; 381(5–6)389–396
  • Coughlin SR. How the protease thrombin talks to cells. Proc Natl Acad Sci USA 1999; 96(20)11023–11027
  • Djellas Y, Antonakis K, Le Breton GC. Shifts in the affinity distribution of one class of seven-transmembrane receptors by activation of a separate class of seven-transmembrane receptors. Biochem Pharmacol 2000; 59(12)1521–1529
  • Savi P, Beauverger P, Labouret C, Delfaud M, Salel V, Kaghad M, Herbert JM. Role of P2Y1 purinoceptor in ADP-induced platelet activation. FEBS Lett 1998; 422(3)291–295
  • Jin J, Daniel JL, Kunapuli SP. Molecular basis for ADP-induced platelet activation. II. The P2Y1 receptor mediates ADP-induced intracellular calcium mobilization and shape change in platelets. J Biol Chem 1998; 273(4)2030–2034
  • Brass LF, Vassallo RR, Jr, Belmonte E, Ahuja M, Cichowski K, Hoxie JA. Structure and function of the human platelet thrombin receptor. Studies using monoclonal antibodies directed against a defined domain within the receptor N terminus. J Biol Chem 1992; 267(20)13795–13798
  • Dorn GW, II. Distinct platelet thromboxane A2/prostaglandin H2 receptor subtypes. A radioligand binding study of human platelets. J Clin Invest 1989; 84(6)1883–1891
  • Halushka PV. Thromboxane A(2) receptors: Where have you gone?. Prostaglandins Other Lipid Mediat 2000; 60(4–6)175–189
  • Nurden P, Savi P, Heilmann E, Bihour C, Herbert JM, Maffrand JP, Nurden A. An inherited bleeding disorder linked to a defective interaction between ADP and its receptor on platelets. Its influence on glycoprotein IIb–IIIa complex function. J Clin Invest 1995; 95(4)1612–1622
  • Quinton TM, Kim S, Derian CK, Jin J, Kunapuli SP. Plasmin-mediated activation of platelets occurs by cleavage of protease-activated receptor 4. J Biol Chem 2004; 279(18)18434–18439
  • Grynkiewicz G, Poenie M, Tsien RY. A new generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol Chem 1985; 260(6)3440–3450
  • Takasaki J, Saito T, Taniguchi M, Kawasaki T, Moritani Y, Hayashi K, Kobori M. A novel Galphaq/11-selective inhibitor. J Biol Chem 2004; 279(46)47438–47445

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.