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Original Articles

Clathrin-mediated integrin αIIbβ3 trafficking controls platelet spreading

, , , , , & show all
Pages 610-621 | Received 15 Feb 2017, Accepted 06 Jul 2017, Published online: 29 Sep 2017

References

  • Gironcel D, Racaud-Sultan C, Payrastre B, Haricot M, Borchert G, Kieffer N, Breton M, Chap H. alphaIIb beta 3-integrin mediated adhesion of human platelets to a fibrinogen matrix triggers phospholipase C activation and phosphatidylinositol 3ʹ,4ʹ-biphosphate accumulation. FEBS Lett 1996;389(3):253–256. doi:10.1016/0014-5793(96)00595-9
  • De Franceschi N, Hamidi H, Alanko J, Sahgal P, Ivaska J. Integrin traffic: The update. J Cell Sci 2015;128(5):839–852. doi:10.1242/jcs.161653
  • Margadant C, Monsuur HN, Norman JC, Sonnenberg A. Mechanisms of integrin activation and trafficking. Curr Opin Cell Biol 2011;23(5):607–614. doi:10.1016/j.ceb.2011.08.005
  • Pellinen T, Ivaska J. Integrin traffic. J Cell Sci 2006;119(Pt 18):3723–3731. doi:10.1242/jcs.03216
  • Israeli-Rosenberg S, Chen C, Li R, Deussen DN, Niesman IR, Okada H, Patel HH, Roth DM, Ross RS. Caveolin modulates integrin function and mechanical activation in the cardiomyocyte. Faseb J 2015;29(2):374–384. doi:10.1096/fj.13-243139
  • Kosaka T, Ikeda K. Reversible blockage of membrane retrieval and endocytosis in the garland cell of the temperature-sensitive mutant of Drosophila melanogaster, shibirets1. J Cell Biol 1983;97(2):499–507. doi:10.1083/jcb.97.2.499
  • Ht M, Boucrot E. Molecular mechanism and physiological functions of clathrin-mediated endocytosis. Nat Rev Mol Cell Biol 2011;12(8):517–533. doi:10.1038/nrm3151
  • Dn B, Oakley JD, Sessions RB, Banting G. Tyrphostin A23 inhibits internalization of the transferrin receptor by perturbing the interaction between tyrosine motifs and the medium chain subunit of the AP-2 adaptor complex. J Biol Chem 2003;278(14):12022–12028. doi:10.1074/jbc.M211966200
  • Schmid SL. Clathrin-coated vesicle formation and protein sorting: An integrated process. Annu Rev Biochem 1997;66:511–548. doi:10.1146/annurev.biochem.66.1.511
  • Irannejad R, Tsvetanova NG, Lobingier BT, Von Zastrow M. Effects of endocytosis on receptor-mediated signaling. Curr Opin Cell Biol 2015;35:137–143. doi:10.1016/j.ceb.2015.05.005
  • Puthenveedu MA, Lauffer B, Temkin P, Vistein R, Carlton P, Thorn K, Taunton J, Weiner OD, Parton RG, Von Zastrow M. Sequence-dependent sorting of recycling proteins by actin-stabilized endosomal microdomains. Cell 2010;143(5):761–773. doi:10.1016/j.cell.2010.10.003
  • Huang Y, Joshi S, Xiang B, Kanaho Y, Li Z, Bouchard BA, Moncman CL, Whiteheart SW. Arf6 controls platelet spreading and clot retraction via integrin alphaIIbbeta3 trafficking. Blood 2016;127(11):1459–1467. doi:10.1182/blood-2015-05-648550
  • Ezratty EJ, Bertaux C, Marcantonio EE, Gundersen GG. Clathrin mediates integrin endocytosis for focal adhesion disassembly in migrating cells. J Cell Biol 2009;187(5):733–747. doi:10.1083/jcb.200904054
  • Von Kleist L, Stahlschmidt W, Bulut H, Gromova K, Puchkov D, Robertson MJ, MacGregor KA, Tomilin N, Pechstein A, Chau N, Chircop M, Sakoff J, Von Kries JP, Saenger W, Krausslich HG, Shupliakov O, Robinson PJ, McCluskey A, Haucke V. Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition. Cell 2011;146(3):471–484. doi:10.1016/j.cell.2011.06.025
  • Guo S, Zhang X, Zheng M, Zhang X, Min C, Wang Z, Cheon SH, Oak MH, Nah SY, Kim KM. Selectivity of commonly used inhibitors of clathrin-mediated and caveolae-dependent endocytosis of G protein-coupled receptors. Biochim Biophys Acta 2015;1848(10 Pt A):2101–2110. doi:10.1016/j.bbamem.2015.05.024
  • Gruner S, Prostredna M, Schulte V, Krieg T, Eckes B, Brakebusch C, Nieswandt B. Multiple integrin-ligand interactions synergize in shear-resistant platelet adhesion at sites of arterial injury in vivo. Blood 2003;102(12):4021–4027. doi:10.1182/blood-2003-05-1391
  • Sm S, Ono A, Nesbitt WS, Lim J, Jarman K, Jackson SP. Phosphoinositide 3-kinase p110 beta regulates integrin alpha IIb beta 3 avidity and the cellular transmission of contractile forces. J Biol Chem 2010;285(4):2886–2896. doi:10.1074/jbc.M109.029132
  • Re B, Norman JC, Caswell PT. Integrin trafficking at a glance. J Cell Sci 2012;125(Pt 16):3695–3701. doi:10.1242/jcs.095810
  • Ch Y, Rafiq NB, Cao F, Zhou Y, Krishnasamy A, Biswas KH, Ravasio A, Chen Z, Wang YH, Kawauchi K, Jones GE, Sheetz MP. Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force. Nat Commun 2015;6:8672. doi:10.1038/ncomms9672
  • Yx Z, Zhu MQ, Jiang M, Zuo B, Wu QY, Ruan CG, He Y. An improved flow cytometric immunobead array to detect autoantibodies in plasma from patients with immune thrombocytopenic purpura. Clin Chim Acta 2015;438:396–400. doi:10.1016/j.cca.2014.09.018
  • Liu J, Jackson CW, Gruppo RA, Jennings LK, Gartner TK. The beta3 subunit of the integrin alphaIIbbeta3 regulates alphaIIb-mediated outside-in signaling. Blood 2005;105(11):4345–4352. doi:10.1182/blood-2004-07-2718
  • Weng Z, Li D, Zhang L, Chen J, Ruan C, Chen G, Gartner TK, Liu J. PTEN regulates collagen-induced platelet activation. Blood 2010;116(14):2579–2581. doi:10.1182/blood-2010-03-277236
  • Yin H, Liu J, Li Z, Berndt MC, Lowell CA, Du X. Src family tyrosine kinase Lyn mediates VWF GPIb-IX induced platelet activation via the cGMP signaling pathway. Blood 2008;112(4):1139–1146. doi:10.1182/blood-2008-02-140970
  • Fan X, Shi P, Dai J, Lu Y, Chen X, Liu X, Zhang K, Wu X, Sun Y, Wang K, Zhu L, Zhang CC, Zhang J, Chen GQ, Zheng J, Liu J. Paired immunoglobulin-like receptor B regulates platelet activation. Blood 2014;124(15):2421–2430. doi:10.1182/blood-2014-03-557645
  • Liu J, Fitzgerald ME, Berndt MC, Jackson CW, Gartner TK. Bruton tyrosine kinase is essential for botrocetin/VWF-induced signaling and GPIb-dependent thrombus formation in vivo. Blood 2006;108(8):2596–2603. doi:10.1182/blood-2006-01-011817
  • Mj C, Liu J, Pestina TI, Steward SA, Thomas DW, Coffman TM, Wang D, Jackson CW, Gartner TK. The roles of alpha IIb beta 3-mediated outside-in signal transduction, thromboxane A2, and adenosine diphosphate in collagen-induced platelet aggregation. Blood 2003;101(7):2646–2651. doi:10.1182/blood-2002-05-1363
  • Dejonghe W, Kuenen S, Mylle E, Vasileva M, Keech O, Viotti C, Swerts J, Fendrych M, Ortiz-Morea FA, Mishev K, et al. Mitochondrial uncouplers inhibit clathrin-mediated endocytosis largely through cytoplasmic acidification. Nat Commun 2016;7:11710. doi:10.1038/ncomms11710
  • Unsworth AJ, Kriek N, Bye AP, Naran K, Sage T, Flora GD, Gibbins JM. PPARgamma agonists negatively regulate alphaIIbbeta3 integrin outside-in signaling and platelet function through up-regulation of protein kinase A activity. J Thromb Haemost 2017;15(2):356–369. doi: 10.1111/jth.13578
  • Hf C, Bzeih H, Schirra C, Chitirala P, Halimani M, Cordat E, E K, Rettig J, Pattu V. Endocytosis of Cytotoxic Granules Is Essential for Multiple Killing of Target Cells by T Lymphocytes. J Immunol 2016;197(6):2473–2484. doi:10.4049/jimmunol.1600828
  • Li Z, Zhang G, Feil R, Han J, Du X. Sequential activation of p38 and ERK pathways by cGMP-dependent protein kinase leading to activation of the platelet integrin alphaIIb beta3. Blood 2006;107(3):965–972. doi:10.1182/blood-2005-03-1308
  • De Franceschi N, Arjonen A, Elkhatib N, Denessiouk K, Wrobel AG, Wilson TA, Pouwels J, Montagnac G, Owen DJ, Ivaska J. Selective integrin endocytosis is driven by interactions between the integrin alpha-chain and AP2. Nat Struct Mol Biol 2016;23(2):172–179. doi:10.1038/nsmb.3161
  • Macia E, Ehrlich M, Massol R, Boucrot E, Brunner C, Kirchhausen T. Dynasore, a cell-permeable inhibitor of dynamin. Dev Cell 2006;10(6):839–850. doi:10.1016/j.devcel.2006.04.002
  • Hj C, Kim GH, Park SH, Hyun JY, Kim NK, Shin I. Probing the effect of an inhibitor of an ATPase domain of Hsc70 on clathrin-mediated endocytosis. Mol Biosyst 2015;11(10):2763–2769. doi:10.1039/C4MB00695J
  • Ma YQ, Qin J, Plow EF. Platelet integrin alpha(IIb)beta(3): Activation mechanisms. J Thromb Haemost 2007;5(7):1345–1352. doi:10.1111/j.1538-7836.2007.02537.x
  • Li Z, Delaney MK, O’Brien KA, Du X. Signaling during platelet adhesion and activation. Arterioscler Thromb Vasc Biol 2010;30(12):2341–2349. doi:10.1161/ATVBAHA.110.207522
  • Gong H, Shen B, Flevaris P, Chow C, Lam SC, Voyno-Yasenetskaya TA, Kozasa T, Du X. G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin “outside-in” signaling. Science 2010;327(5963):340–343. doi:10.1126/science.1174779
  • Ya S, Mazharian A, Mori J. Src family kinases: At the forefront of platelet activation. Blood 2014;124(13):2013–2024. doi:10.1182/blood-2014-01-453134
  • Wonerow P, Pearce AC, Vaux DJ, Watson SP. A critical role for phospholipase Cgamma2 in alphaIIbbeta3-mediated platelet spreading. J Biol Chem 2003;278(39):37520–37529. doi:10.1074/jbc.M305077200
  • Estevez B, Shen B, Du X. Targeting integrin and integrin signaling in treating thrombosis. Arterioscler Thromb Vasc Biol 2015;35(1):24–29. doi:10.1161/ATVBAHA.114.303411
  • Fm B. Diversity of clathrin function: new tricks for an old protein. Annu Rev Cell Dev Biol 2012;28:309–336. doi:10.1146/annurev-cellbio-101011-155716
  • Hishinuma S, Nozawa H, Akatsu C, Shoji M. C-terminal of human histamine H1 receptors regulates their agonist-induced clathrin-mediated internalization and G-protein signaling. J Neurochem 2016. doi:10.1111/jnc.13834
  • Lemmon SK, Traub LM. Getting in touch with the clathrin terminal domain. Traffic 2012;13(4):511–519. doi:10.1111/j.1600-0854.2011.01321.x
  • Ng T, Shima D, Squire A, Bastiaens PI, Gschmeissner S, Humphries MJ, Parker PJ. PKCalpha regulates beta1 integrin-dependent cell motility through association and control of integrin traffic. Embo J 1999;18(14):3909–3923. doi:10.1093/emboj/18.14.3909
  • Korolchuk V, Banting G. Kinases in clathrin-mediated endocytosis. Biochem Soc Trans 2003;31(Pt 4):857–860. doi:10.1042/bst0310857
  • Baurand A, Eckly A, Hechler B, Kauffenstein G, Galzi JL, Cazenave JP, Leon C, Gachet C. Differential regulation and relocalization of the platelet P2Y receptors after activation: a way to avoid loss of hemostatic properties? Mol Pharmacol 2005;67(3):721–733. doi:10.1124/mol.104.004846
  • Sw B, Nooh MM. Barcoding of GPCR trafficking and signaling through the various trafficking roadmaps by compartmentalized signaling networks. Cell Signal 2017;36:42–55. doi:10.1016/j.cellsig.2017.04.015
  • Michaux G, Dyer CE, Nightingale TD, Gallaud E, Nurrish S, Cutler DF. A role for Rab10 in von Willebrand factor release discovered by an AP-1 interactor screen in C. Elegans J Thromb Haemost 2011;9(2):392–401. doi:10.1111/j.1538-7836.2010.04138.x

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