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Commentary

Platelet integrin activation surfs the calcium waves

ORCID Icon, ORCID Icon, &
Pages 437-439 | Received 06 Apr 2020, Accepted 08 May 2020, Published online: 22 May 2020

References

  • Watson SP, Auger JM, McCarty OJT, Pearce AC. GPVI and integrin αIIbβ3 signaling in platelets. J Thromb Haemost 2005;3(8):1752–1762. doi:10.1111/j.1538-7836.2005.01429.x
  • French DL, Seligsohn U. Platelet Glycoprotein IIb/IIIa receptors and Glanzmann’s thrombasthenia. Arterioscler Thromb Vasc Biol 2000;20(3):607–610. doi:10.1161/01.ATV.20.3.607
  • Lakshmanan HHS, Melrose AR, Sepp A-LI, Mitrugno A, Ngo ATP, Khader A, Thompson R, Sallee D, Pang J, Mangin PH, et al. The basement membrane protein nidogen-1 supports platelet adhesion and activation. Platelets Apr 2020:1–5. doi:10.1080/09537104.2020.1745170. [ Epub ahead of print].
  • Inoue O, Suzuki-Inoue K, McCarty OJT, Moroi M, Ruggeri ZM, Kunicki TJ, Ozaki Y, Watson SP. Laminin stimulates spreading of platelets through integrin α6β1-dependent activation of GPVI. Blood 2006;107(4):1405–1412. doi:10.1182/blood-2005-06-2406
  • Mccarty OJT, Zhao Y, Andrew N, Machesky LM, Staunton D, Frampton J, Watson SP. Evaluation of the role of platelet integrins in fibronectin-dependent spreading and adhesion. J Thromb Haemost 2004;2(10):1823–1833. doi:10.1111/j.1538-7836.2004.00925.x
  • Sun DS, Lo SJ, Tsai WJ, Lin C-H, Yu M-S, Chen Y-F, Chang -H-H. PI3-kinase is essential for ADP-stimulated integrin α IIbβ3-mediated platelet calcium oscillation, implications for P2Y receptor pathways in integrin αIIbβ 3-initiated signaling cross-talks. J Biomed Sci 2005;12(6):937–948. doi:10.1007/s11373-005-9016-z
  • Cosemans JMEM, Munnix ICA, Wetzker R, Heller R, Jackson SP, Heemskerk JWM. Continuous signaling via PI3K isoforms β and γ is required for platelet ADP receptor function in dynamic thrombus stabilization. Blood 2006;108(9):3045–3052. doi:10.1182/blood-2006-03-006338
  • Schoenwaelder SM, Ono A, Sturgeon S, Chan SM, Mangin P, Maxwell MJ, Turnbull S, Mulchandani M, Anderson K, Kauffenstein G, et al. Identification of a unique co-operative phosphoinositide 3-kinase signaling mechanism regulating integrin αIIbβ3 adhesive function in platelets. J Biol Chem 2007;282(39):28648–28658. doi:10.1074/jbc.M704358200
  • Obydennyy SI, Sveshnikova AN, Ataullakhanov FI, Panteleev MA. Dynamics of calcium spiking, mitochondrial collapse and phosphatidylserine exposure in platelet subpopulations during activation. J Thromb Haemost 2016;14(9):1867–1881. doi:10.1111/jth.13395
  • Heemskerk JWM, Hoyland J, Mason WT, Sage SO. Spiking in cytosolic calcium concentration in single fibrinogen-bound fura-2-loaded human platelets. Biochem J 1992;283(2):379–383. doi:10.1042/bj2830379
  • Mazzucato M, Cozzi MR, Battiston M, Jandrot-Perrus M, Mongiat M, Marchese P, Kunicki TJ, Ruggeri ZM, De Marco L. Distinct spatio-temporal Ca2+ signaling elicited by integrin α2β1 and glycoprotein VI under flow. Blood 2009;114(13):2793–2801. doi:10.1182/blood-2008-12-193490
  • Bye AP, Gibbins JM, Mahaut-Smith MP. Ca2+ waves coordinate purinergic receptor-evoked integrin activation and polarization. Sci Signal 2020;13(615). doi:10.1126/scisignal.aav7354
  • Tolhurst G, Vial C, Léon C, Gachet C, Evans RJ, Mahaut-Smith MP. Interplay between P2Y1, P2Y12, and P2X1 receptors in the activation of megakaryocyte cation influx currents by ADP: evidence that the primary megakaryocyte represents a fully functional model of platelet P2 receptor signaling. Blood 2005;106(5):1644–1651. doi:10.1182/blood-2005-02-0725

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