References
- Myron P, Siddiquee S, Azad SA. Fucosylated chondroitin sulfate diversity in sea cucumbers: a review. Carbohydr Polym 2014;112:173–178. doi:https://doi.org/10.1016/j.carbpol.2014.05.091
- Shang F, Gao N, Yin R, Lin L, Xiao C, Zhou L, Li Z, Purcell SW, Wu M, Zhao J. Precise structures of fucosylated glycosaminoglycan and its oligosaccharides as novel intrinsic factor Xase inhibitors. Eur J Med Chem 2018;148:423–435. doi:https://doi.org/10.1016/j.ejmech.2018.02.047
- Pomin VH. Holothurian fucosylated chondroitin sulfate. Mar Drugs 2014;12(1):232–254. doi:https://doi.org/10.3390/md12010232
- Cai Y, Yang W, Li X, Zhou L, Wang Z, Lin L, Chen D, Zhao L, Li Z, Liu S, et al.. Precise structures and anti-intrinsic tenase complex activity of three fucosylated glycosaminoglycans and their fragments. Carbohydr Polym 2019;224:115146. doi:https://doi.org/10.1016/j.carbpol.2019.115146
- Lin L, Zhao L, Gao N, Yin R, Li S, Sun H, Zhou L, Zhao G, Purcell SW, Zhao J. From multi-target anticoagulants to DOACs, and intrinsic coagulation factor inhibitors. Blood Rev 2019;39:100615.
- Sheehan JP, Walke EN. Depolymerized holothurian glycosaminoglycan and heparin inhibit the intrinsic tenase complex by a common antithrombin-independent mechanism. Blood 2006;107(10):3876–3882. doi:https://doi.org/10.1182/blood-2005-07-3043
- Nagase H, Enjyoji K, Minamiguchi K, Kitazato KT, Kitazato K, Saito H, Kato H. Depolymerized holothurian glycosaminoglycan with novel anticoagulant actions: antithrombin III- and heparin cofactor II-independent inhibition of factor X activation by factor IXa-factor VIIIa complex and heparin cofactor II-dependent inhibition of thrombin. Blood 1995;85:1527–1534.
- Xiao C, Zhao L, Gao N, Wu M, Zhao J. Nonasaccharide inhibits intrinsic factor Xase complex by binding to factor IXa and disrupting factor IXa-factor VIIIa interactions. Thromb Haemost 2019;119:705–715. doi:https://doi.org/10.1055/s-0039-1681047
- Fonseca RJ, Oliveira SN, Pomin VH, Mecawi AS, Araujo IG, Mourão PAS. Effects of oversulfated and fucosylated chondroitin sulfates on coagulation. Challenges for the study of anticoagulant polysaccharides. Thromb Haemost 2010;103:994–1004. doi:https://doi.org/10.1160/TH09-10-0734
- Wu M, Wen D, Gao N, Xiao C, Yang L, Xu L, Lian W, Peng W, Jiang J, Zhao J. Anticoagulant and antithrombotic evaluation of native fucosylated chondroitin sulfates and their derivatives as selective inhibitors of intrinsic factor Xase. Eur J Med Chem 2015;92:257–269. doi:https://doi.org/10.1016/j.ejmech.2014.12.054
- Shen D. Shen Di’s disease (Article in Chinese). Chin J Pract Int Med 1989;9:520.
- Li J, Bao C, Chen G, Zhang G, Fan H, J C. Antithrombin activity and platelet aggregation by acid mucopolysaccharides isolated from Stichopus japonicus Selenka [Article in Chinese]. Acta Pharmacol Sin 1985;6:107–110.
- Li J, Lian EC. Aggregation of human platelets by acidic mucopolysaccharide extracted from Stichopus japonicus Selenka. Thromb Haemost 1988;59:435–439. doi:https://doi.org/10.1055/s-0038-1647511
- Li J, Lian EC. Mechanism of rabbit platelet agglutination induced by acidic mucopolysaccharide extracted from Stichopus japonicus Selenka. Thromb Haemost 1988;59:432–434. doi:https://doi.org/10.1055/s-0038-1647510
- Zhang W, Shen D, Wang A, Zhongping L. Effects of Stichopus Japonicus acidic mucopolysaccharide (SJAMP) on platelet cAMP level [article in Chinese]. Chin Hosp Pharm 1991;11:3–5.
- Guo T, Shen D, Song S, Wei W. Effect of SJAMP on ATP release of platelet. J Tongji Med Univ 1999;19:102–104. doi:https://doi.org/10.1007/BF02886886
- Copeland CE, Six CK. A tale of two anticoagulants: warfarin and heparin. J Surg Educ 2009;66:176–181. doi:https://doi.org/10.1016/j.jsurg.2009.03.035
- Giangiacomo T, Naggi A. Heparin centenary—an ever-young life-saving drug. Int J Cardiol 2016;212:S1–S4. doi:https://doi.org/10.1016/S0167-5273(16)12001-7
- Arepally G. Heparin-induced thrombocytopenia. Blood 2017;129(21):2864–2872. doi:https://doi.org/10.1182/blood-2016-11-709873
- Sobel M, Fish WR, Toma N, Luo S, Bird K, Mori K, Kusumoto S, Blystone SD, Suda Y. Blystone SD and Suda Y. Heparin modulates integrin function in human platelets. J Vasc Surg 2001;33(3):587–594. doi:https://doi.org/10.1067/mva.2001.112696
- Gao C, Boylan B, Fang J, Wilcox DA. Newman DK and Newman PJ. Heparin promotes platelet responsiveness by potentiating alphaIIbbeta3-mediated outside-in signaling. Blood 2011;117:4946–4952. doi:https://doi.org/10.1182/blood-2010-09-307751
- Yagi M, Murray J, Strand K, Blystone S, Interlandi G, Suda Y, Sobel M. Heparin modulates the conformation and signaling of platelet integrin alphaIIbbeta3. Thromb Res 2012;129:743–749. doi:https://doi.org/10.1016/j.thromres.2011.11.054
- Kishimoto TK, Viswanathan K, Ganguly T, Elankumaran S, Smith S, Pelzer K, Lansing JC, Sriranganathan N, Zhao G, Galcheva-Gargova Z, et al.. Contaminated heparin associated with adverse clinical events and activation of the contact system. N Engl J Med 2008;358(23):2457–2467. doi:https://doi.org/10.1056/NEJMoa0803200
- Zhao L, Wu M, Xiao C, Yang L, Zhou L, Gao N, Li Z, Chen J, Chen J, Liu J, et al.. Discovery of an intrinsic tenase complex inhibitor: pure nonasaccharide from fucosylated glycosaminoglycan. Proc Natl Acad Sci U S A 2015;112(27):8284–8289. doi:https://doi.org/10.1073/pnas.1504229112
- Yin R, Zhou L, Gao N, Li Z, Zhao L, Shang F, Wu M, Zhao J. Oligosaccharides from depolymerized fucosylated glycosaminoglycan: structures and minimum size for intrinsic factor Xase complex inhibition. J Biol Chem 2018;293(36):14089–14099. doi:https://doi.org/10.1074/jbc.RA118.003809
- Gao N, Lu F, Xiao C, Yang L, Chen J, Zhou K, Wen D, Li Z, Wu M, Jiang J, et al.. β-Eliminative depolymerization of the fucosylated chondroitin sulfate and anticoagulant activities of resulting fragments. Carbohydr Polym 2015;127:427–437. doi:https://doi.org/10.1016/j.carbpol.2015.04.002
- Lin L, Xu L, Xiao C, Zhou L, Gao N, Wu M, Zhao J. Plasma contact activation by a fucosylated chondroitin sulfate and its structure–activity relationship study. Glycobiology 2018;28(10):754–764. doi:https://doi.org/10.1093/glycob/cwy067
- Lin L, Wu M, Zhao J. The initiation and effects of plasma contact activation: an overview. Int J Hematol 2017;105(3):235–243. doi:https://doi.org/10.1007/s12185-016-2132-x
- Wu M, Huang R, Wen D, Gao N, He J, Li Z, Zhao J. Structure and effect of sulfated fucose branches on anticoagulant activity of the fucosylated chondroitin sulfate from sea cucumber Thelenata ananas. Carbohydr Polym 2012;87(1):862–868. doi:https://doi.org/10.1016/j.carbpol.2011.08.082
- Zhao L, Lai S, Huang R, Wu M, Gao N, Xu L, Qin H, Peng W, Zhao J. Structure and anticoagulant activity of fucosylated glycosaminoglycan degraded by deaminative cleavage. Carbohydr Polym 2013;98(2):1514–1523. doi:https://doi.org/10.1016/j.carbpol.2013.07.063
- Born GVR, Cross M. The aggregation of blood platelets. J Physiol 1963;168(1):178–195. doi:https://doi.org/10.1113/jphysiol.1963.sp007185
- Cho MJ, Liu J, Pestina TI, Steward SA, Jackson CW, Gartner T. AlphaIIbbeta3-mediated outside-in signaling induced by the agonist peptide LSARLAF utilizes ADP and thromboxane A2 receptors to cause alpha-granule secretion by platelets. J Thromb Haemost 2003;1(2):363–373. doi:https://doi.org/10.1046/j.1538-7836.2003.00055.x
- Charo IF, Feinman RD, Detwiler T. Interrelations of platelet aggregation and secretion. J Clin Invest 1977;60(4):866–873. doi:https://doi.org/10.1172/JCI108841
- Coller BS, Gralnick H. Studies on the mechanism of ristocetin-induced platelet agglutination. Effects of structural modification of ristocetin and vancomycin. J Clin Invest 1977;60(2):302–312. doi:https://doi.org/10.1172/JCI108778
- Coller B. Polybrene-induced platelet agglutination and reduction in electrophoretic mobility. Blood 1980;55:276–281. doi:https://doi.org/10.1182/blood.V55.2.276.276
- Payrastre B, Missy K, Trumel C, Bodin S, Plantavid M, Chap H. The integrin αIIbβ3 in human platelet signal transduction. Biochem Pharmacol 2000;60:1069–1074. doi:https://doi.org/10.1016/S0006-2952(00)00417-2
- Jin J, Quinton TM, Zhang J, Rittenhouse SE, Kunapuli S. Adenosine diphosphate (ADP)–induced thromboxane A2 generation in human platelets requires coordinated signaling through integrin αIIbβ3 and ADP receptors. Blood 2002;99:193–198. doi:https://doi.org/10.1182/blood.V99.1.193
- Li Z, Zhang G, Le Breton GC, Gao X, Malik AB, Du X. Two waves of platelet secretion induced by thromboxane A2 receptor and a critical role for phosphoinositide 3-kinases. J Biol Chem 2003;278:30725–30731. doi:https://doi.org/10.1074/jbc.M301838200
- Durrant TN, van dIngeborg H, van den Bosch MT, Hers I. Integrin alphaIIbbeta3 outside-in signaling. Blood 2017;130:1607–1619. doi:https://doi.org/10.1182/blood-2017-03-773614
- Du X, Plow EF, Frelinger AL, O’Toole TE, Loftus JC, Ginsberg MH. Ligands ‘activate” integrin αIIbβ3 (platelet GPllb-llla). Cell 1991;65:409–416. doi:https://doi.org/10.1016/0092-8674(91)90458-B
- Cattaneo M, Gachet C, Cazenave JP, Packham M. Adenosine diphosphate (ADP) does not induce thromboxane A2 generation in human platelets. Blood 2002;99:3868–3869. doi:https://doi.org/10.1182/blood-2002-01-0313
- Manne BK, Getz TM, Hughes CE, Alshehri O, Dangelmaier C, Naik UP, Watson SP, Kunapuli SP. Fucoidan is a novel platelet agonist for the C-type lectin-like receptor 2 (CLEC-2). J Biol Chem 2013;288(11):7717–7726. doi:https://doi.org/10.1074/jbc.M112.424473
- Getz TM, Manne BK, Buitrago L, Mao Y, Kunapuli SP. Dextran sulphate induces fibrinogen receptor activation through a novel Syk-independent PI-3 kinase-mediated tyrosine kinase pathway in platelets. Thromb Haemost 2013;109(06):1131–1140. doi:https://doi.org/10.1160/TH12-09-0645
- Vandenbriele C, Sun Y, Criel M, Cludts K, Van Kerckhoven S, Izzi B, Vanassche T, Verhamme P, Hoylaerts MF. Dextran sulfate triggers platelet aggregation via direct activation of PEAR1. Platelets 2016;27(4):365–372. doi:https://doi.org/10.3109/09537104.2015.1111321