Characteristics of L-PRP preparations for treating Achilles tendon rupture within the PATH-2 study

References

• Nurden AT. Platelets, inflammation and tissue regeneration. Thromb Haemost 2011;105(Suppl S 06):S13–33. doi:10.1160/THS10-11-0720.
   PubMedGoogle Scholar
• Rachul C, Rasko JEJ, Caulfield T. Implicit hype? Representations of platelet rich plasma in the news media. PLoS One 2017;12:e0182496.
   PubMed Web of Science ®Google Scholar
• Alsousou J, Harrison P. Platelet-rich plasma in regenerative medicine. In: Gresele KN, Lopez P, Page J, editors. Platelets in thrombotic and non-thrombotic disorders. Cham: Springer; 2017.
   Google Scholar
• Alsousou J, Ali A, Willett K, Harrison P. The role of platelet-rich plasma in tissue regeneration. Platelets 2013;24:173–182.
   PubMed Web of Science ®Google Scholar
• Alves R, Grimalt R. A review of platelet-rich plasma: history, biology, mechanism of action, and classification. Skin Appendage Disord 2018;4:18–24.
   PubMed Web of Science ®Google Scholar
• Anitua E, Andia I, Ardanza B, Nurden P, Nurden AT. Autologous platelets as a source of proteins for healing and tissue regeneration. Thromb Haemost 2004;91:4–15.
   PubMed Web of Science ®Google Scholar
• Harrison P; Subcommittee on Platelet, P. The use of platelets in regenerative medicine and proposal for a new classification system: guidance from the SSC of the ISTH. J Thromb Haemost 2018;16:1895–1900.
   PubMed Web of Science ®Google Scholar
• Moreno R, Gaspar Carreno M, Alonso Herreros JM, Romero Garrido JA, Lopez-Sanchez P. [Platelet-rich plasma: updating of extraction devices]. Farm Hosp 2016;40:385–393.
   PubMedGoogle Scholar
• de Melo BAG, Martins Shimojo AA, Marcelino Perez AG, Duarte Lana JFS, Andrade Santana MH. Distribution, recovery and concentration of platelets and leukocytes in L-PRP prepared by centrifugation. Colloids Surf B Biointerfaces 2017;161:288–295.
   PubMed Web of Science ®Google Scholar
• Sharma NK. Platelet-rich fibrin: emerging biomaterial in regeneration. Natl J Maxillofac Surg 2018;105: 1. doi:10.4103/njms.NJMS_40_18.
   Google Scholar
• Dohan Ehrenfest DM, Rasmusson L, Albrektsson T. Classification of platelet concentrates: from pure platelet-rich plasma (P-PRP) to leucocyte- and platelet-rich fibrin (L-PRF). Trends Biotechnol 2009;27: 158–167. doi:10.1016/j.tibtech.2008.11.009.
   PubMed Web of Science ®Google Scholar
• Magalon J, Chateau AL, Bertrand B, Louis ML, Silvestre A, Giraudo L, Veran J, Sabatier F. DEPA classification: a proposal for standardising PRP use and a retrospective application of available devices. BMJ Open Sport Exerc Med 2016;2:e000060.
   PubMedGoogle Scholar
• Chahla J, Cinque ME, Piuzzi NS, Mannava S, Geeslin AG, Murray IR, Dornan GJ, Muschler GF, LaPrade RF. A call for standardization in platelet-rich plasma preparation protocols and composition reporting: a systematic review of the clinical orthopaedic literature. J Bone Joint Surg Am 2017;99:1769–1779.
   PubMed Web of Science ®Google Scholar
• Marques LF, Stessuk T, Camargo IC, Sabeh Junior N, Dos Santos L, Ribeiro-Paes JT. Platelet-rich plasma (PRP): methodological aspects and clinical applications. Platelets 2015;26:101–113.
   PubMed Web of Science ®Google Scholar
• Murray IR, Geeslin AG, Goudie EB, Petrigliano FA, LaPrade RF. Minimum information for studies evaluating biologics in orthopaedics (MIBO): platelet-rich plasma and mesenchymal stem cells. J Bone Joint Surg Am 2017;99:809–819.
   PubMed Web of Science ®Google Scholar
• DeLong JM, Russell RP, Mazzocca AD. Platelet-rich plasma: the PAW classification system. Arthroscopy 2012;28:998–1009.
   PubMed Web of Science ®Google Scholar
• Mautner K, Malanga GA, Smith J, Shiple B, Ibrahim V, Sampson S, Bowen JE. A call for a standard classification system for future biologic research: the rationale for new PRP nomenclature. Pm R 2015;7:S53–9.
   PubMedGoogle Scholar
• Oda H, Sano K, Kunimasa Y, Komi PV, Ishikawa M. Neuromechanical modulation of the achilles tendon during bilateral hopping in patients with unilateral achilles tendon rupture, over 1 year after surgical repair. Sports Med 2017;47:1221–1230.
   PubMed Web of Science ®Google Scholar
• Maffulli N, Longo UG, Maffulli GD, Rabitti C, Khanna A, Denaro V. Marked pathological changes proximal and distal to the site of rupture in acute Achilles tendon ruptures. Knee Surg Sports Traumatol Arthrosc 2011;19:680–687.
   PubMed Web of Science ®Google Scholar
• De Carli A, Lanzetti RM, Ciompi A, Lupariello D, Vadala A, Argento G, Ferretti A, Vulpiani MC, Vetrano M. Can platelet-rich plasma have a role in Achilles tendon surgical repair? Knee Surg Sports Traumatol Arthrosc 2016;24:2231–2237.
   PubMed Web of Science ®Google Scholar
• Alsousou J, Thompson M, Harrison P, Willett K, Franklin S. Effect of platelet-rich plasma on healing tissues in acute ruptured Achilles tendon: a human immunohistochemistry study. Lancet 2015;385(Suppl 1):S19.
   PubMedGoogle Scholar
• Alsousou J, Keene DJ, Hulley PA, Harrison P, Wagland S, Byrne C, Schlussel MM, Dutton SJ, Lamb SE, Willett K. Platelet rich plasma in achilles tendon healing 2 (PATH-2) trial: protocol for a multicentre, participant and assessor-blinded, parallel-group randomised clinical trial comparing platelet-rich plasma (PRP) injection versus placebo injection for Achilles tendon rupture. BMJ Open 2017;7:e018135.
   PubMed Web of Science ®Google Scholar
• Degen RM, Bernard JA, Oliver KS, Dines JS. Commercial separation systems designed for preparation of platelet-rich plasma yield differences in cellular composition. Hss J 2017;13:75–80.
   PubMedGoogle Scholar
• Dovlatova N, Lordkipanidze M, Lowe GC, Dawood B, May J, Heptinstall S, Watson SP, Fox SC, Group UGS. Evaluation of a whole blood remote platelet function test for the diagnosis of mild bleeding disorders. J Thromb Haemost 2014;12:660–665.
   PubMed Web of Science ®Google Scholar
• Briggs C, Longair I, Kumar P, Singh D, Machin SJ. Performance evaluation of the Sysmex haematology XN modular system. J Clin Pathol 2012;65:1024–1030.
   PubMed Web of Science ®Google Scholar
• Harrison P, Wilbourn B, Debili N, Vainchenker W, Breton-Gorius J, Lawrie AS, Masse JM, Savidge GF, Cramer EM. Uptake of plasma fibrinogen into the alpha granules of human megakaryocytes and platelets. J Clin Invest 1989;84:1320–1324.
   PubMed Web of Science ®Google Scholar
• Keene DJ, Alsousou J, Harrison P, Hulley P, Wagland S, Parsons SR, Thompson JY, O’Connor HM, Schlussel MM, Dutton SJ, et al.; group, P.-t. Platelet rich plasma injection for acute Achilles tendon rupture: PATH-2 randomised, placebo controlled, superiority trial. BMJ 2019;367:l6132.
   PubMedGoogle Scholar
• Alsousou J, Keene DJ, Harrison P, Hulley P, Wagland S, Thompson JY, Parsons SR, Byrne C, Schlussel MM, O’Connor HM, et al. In Platelet-rich plasma injection for adults with acute Achilles tendon rupture: the PATH-2 RCT, Southampton (UK). 2019.
   Google Scholar
• Kushida S, Kakudo N, Morimoto N, Hara T, Ogawa T, Mitsui T, Kusumoto K. Platelet and growth factor concentrations in activated platelet-rich plasma: a comparison of seven commercial separation systems. J Artif Organs 2014;17:186–192.
   PubMed Web of Science ®Google Scholar
• Castillo TN, Pouliot MA, Kim HJ, Dragoo JL. Comparison of growth factor and platelet concentration from commercial platelet-rich plasma separation systems. Am J Sports Med 2011;39:266–271.
   PubMed Web of Science ®Google Scholar
• Patel AN, Selzman CH, Kumpati GS, McKellar SH, Bull DA. Evaluation of autologous platelet rich plasma for cardiac surgery: outcome analysis of 2000 patients. J Cardiothorac Surg 2016;11:62.
   PubMed Web of Science ®Google Scholar
• Zhou Y, Zhang J, Wu H, Hogan MV, Wang JH. The differential effects of leukocyte-containing and pure platelet-rich plasma (PRP) on tendon stem/progenitor cells - implications of PRP application for the clinical treatment of tendon injuries. Stem Cell Res Ther 2015;6:173.
   PubMed Web of Science ®Google Scholar
• Everts PA, Malanga GA, Paul RV, Rothenberg JB, Stephens N, Mautner KR. Assessing clinical implications and perspectives of the pathophysiological effects of erythrocytes and plasma free hemoglobin in autologous biologics for use in musculoskeletal regenerative medicine therapies. A Review. Regen Ther 2019;11:56–64.
   PubMed Web of Science ®Google Scholar
• Oudelaar BW, Peerbooms JC, Huis in ‘T Veld R, Vochteloo AJH. Concentrations of blood components in commercial platelet-rich plasma separation systems: a review of the literature. Am J Sports Med 2019;47:479–487.
   PubMed Web of Science ®Google Scholar