169
Views
0
CrossRef citations to date
0
Altmetric
Research Articles

S1R agonist modulates rat platelet eicosanoid synthesis and aggregation

ORCID Icon, , ORCID Icon, , , , , ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon show all
Pages 709-718 | Received 09 Feb 2021, Accepted 14 Sep 2021, Published online: 26 Oct 2021

References

  • Zhang K, et al., Sigma-1 receptor plays a negative modulation on N-type calcium channel. Front Pharmacol 2017;8:302. 10.3389/fphar.2017.00302.
  • Penke B, Fulop L, Szucs M, Frecska E. The role of Sigma-1 receptor, an intracellular chaperone in neurodegenerative diseases. Curr Neuropharmacol 2018;16(1):97–116. 10.2174/1570159X15666170529104323.
  • Nguyen L,et al., Role of sigma-1 receptors in neurodegenerative diseases. J Pharmacol Sci 2015;127(1):17–29. 10.1016/j.jphs.2014.12.005.
  • Maurice T, Su T-P. The pharmacology of sigma-1 receptors. Pharmacol Ther 2009;124(2):195–206. 10.1016/j.pharmthera.2009.07.001.
  • Wang J, et al., Anti-inflammatory and analgesic actions of bufotenine through inhibiting lipid metabolism pathway. Biomed Pharmacother 2021;140:111749. 10.1016/j.biopha.2021.111749.
  • Hayashi T, Su T-P. The potential role of sigma-1 receptors in lipid transport and lipid raft reconstitution in the brain: implication for drug abuse. Life Sci 2005;77(14):1612–1624. 10.1016/j.lfs.2005.05.009.
  • Morales-Lázaro SL, González-Ramírez R, Rosenbaum T. Molecular interplay between the Sigma-1 receptor, steroids, and ion channels. Front Pharmacol 2019;10. 419. 10.3389/fphar.2019.00419.
  • Starr JB, Werling LL. σ-receptor regulation of [3H]arachidonic acid release from rat neonatal cerebellar granule cells in culture. J Neurochem 2002;63(4):1311–1318. 10.1046/j.1471-4159.1994.63041311.x.
  • Paes AM de A, Gaspar RS, Fuentes E, Wehinger S, Palomo I, Trostchansky A. Lipid metabolism and signaling in platelet function. Adv Exp Med Biol 2019;1127. 97–115. 10.1007/978-3-030-11488-6_7.
  • Jia J, Cheng J, Wang C, Zhen X. Sigma-1 receptor-modulated neuroinflammation in neurological diseases. Front Cell Neurosci 2018;12. 314. 10.3389/fncel.2018.00314.
  • Rawish E, Nording H, Münte T, Langer HF. Platelets as mediators of neuroinflammation and thrombosis. Front Immunol 2020;11. 548631. 10.3389/fimmu.2020.548631.
  • Su T-P, Su T-C, Nakamura Y, Tsai S-Y. The Sigma-1 receptor as a pluripotent modulator in living systems. Trends Pharmacol Sci 2016;37(4):262–278. 10.1016/j.tips.2016.01.003.
  • Aishwarya R, Abdullah CS, Morshed M, Remex NS, Bhuiyan MS. Sigmar1’s molecular, cellular, and biological functions in regulating cellular pathophysiology. Front Physiol 2021;12. 705575. 10.3389/fphys.2021.705575.
  • Cobos EJ, Entrena JM, Nieto FR, Cendán CM, Del Pozo E. Pharmacology and therapeutic potential of sigma(1) receptor ligands. Curr Neuropharmacol 2008;6(4):344–366. 10.2174/157015908787386113.
  • Schlienger RG, Meier CR. Effect of selective serotonin reuptake inhibitors on platelet activation: can they prevent acute myocardial infarction? Am J Cardiovasc Drugs 2003;3(3):149–162. 10.2165/00129784-200303030-00001.
  • Horstman LL, et al., Role of platelets in neuroinflammation: a wide-angle perspective. J Neuroinflammation 2010;7:10. 10.1186/1742-2094-7-10.
  • Thomas MR, Storey RF. The role of platelets in inflammation. Thromb Haemost 2015;114(3):449–458. 10.1160/TH14-12-1067.
  • Bhuiyan MS, Tagashira H, Fukunaga K. Dehydroepiandrosterone-mediated stimulation of sigma-1 receptor activates Akt-eNOS signaling in the thoracic aorta of ovariectomized rats with abdominal aortic banding. Cardiovascular Therapeutics 2011;29(4):219–230. 10.1111/j.1755-5922.2010.00196.x.
  • Tagashira H, et al., Vascular endothelial σ1-receptor stimulation with SA4503 rescues aortic relaxation via Akt/eNOS signaling in ovariectomized rats with aortic banding. Circ J 2013;77(11):2831–2840. 10.1253/circj.cj-13-0256.
  • Hosszu A, et al., σ1-receptor agonism protects against renal ischemia-reperfusion injury. J Am Soc Nephrol 2017;28(1):152–165. 10.1681/ASN.2015070772.
  • Gao Q-J, Yang B, Chen J, Shi S-B, Yang H-J LX, Liu X. Sigma-1 receptor stimulation with PRE-084 ameliorates myocardial ischemia-reperfusion injury in rats. Chin Med J (Engl) 2018;131(5):539–543. 10.4103/0366-6999.226076.
  • Nardai S, et al., N,N-dimethyltryptamine reduces infarct size and improves functional recovery following transient focal brain ischemia in rats. Exp Neurol 2020;327:113245. 10.1016/j.expneurol.2020.113245.
  • Allahtavakoli M, Jarrott B. Sigma-1 receptor ligand PRE-084 reduced infarct volume, neurological deficits, pro-inflammatory cytokines and enhanced anti-inflammatory cytokines after embolic stroke in rats. Brain Res Bull 2011;85(3–4):219–224. 10.1016/j.brainresbull.2011.03.019.
  • Rosen DA,et al., Modulation of the sigma-1 receptor-IRE1 pathway is beneficial in preclinical models of inflammation and sepsis. Sci Transl Med 2019;11(478):eaau5266. 10.1126/scitranslmed.aau5266.
  • Mezei Z, Kis B, Gecse A, Telegdy G, Abrahám G, Sonkodi S. Platelet eicosanoids and the effect of captopril in blood pressure regulation. Eur J Pharmacol 1997;340(1):67–73. 10.1016/s0014-2999(97)01402-7.
  • Mezei Z, et al., Platelet arachidonate cascade of migraineurs in the interictal phase. Platelets 2000;11(4):222–225. 10.1080/09537100050057666.
  • Jiang G,et al., Expression, subcellular localization, and regulation of sigma receptor in retinal muller cells. Invest Ophthalmol Vis Sci 2006;47(12):5576–5582. 10.1167/iovs.06-0608.
  • Zhang H, et al., Expression of the 78 kD glucose-regulated protein is induced by endoplasmic reticulum stress in the development of hepatopulmonary syndrome. Gene 2014;537(1):115–119. 10.1016/j.gene.2013.11.065.
  • van Zijp HM, et al., Quantification of platelet-surface interactions in real-time using intracellular calcium signaling. Biomed Microdevices 2014;16(2):217–227. 10.1007/s10544-013-9825-1.
  • Abdel-Halim MS, Lundén I, Cseh G, Anggård E. Prostaglandin profiles in nervous tissue and blood vessels of the brain of various animals. Prostaglandins 1980;19(2):249–258. 10.1016/0090-6980(80)90023-4.
  • Cryer B. Management of patients with high gastrointestinal risk on antiplatelet therapy. Gastroenterol Clin North Am 2009;38(2):289–303. 10.1016/j.gtc.2009.03.005.
  • Kis B, et al., Vasoactive substances produced by cultured rat brain endothelial cells. Eur J Pharmacol 1999;368(1):35–42. 10.1016/s0014-2999(99)00024-2.
  • Mezei Z,et al., The effect of kisspeptin on the regulation of vascular tone. Can J Physiol Pharmacol 2015;93(9):787–791. 10.1139/cjpp-2015-0013.
  • Mezei Z, et al., Effects of kisspeptin on diabetic rat platelets. Can J Physiol Pharmacol 2017;95(11):1319–1326. 10.1139/cjpp-2017-0036.
  • Tóth O, Calatzis A, Penz S, Losonczy H, Siess W. Multiple electrode aggregometry: a new device to measure platelet aggregation in whole blood. Thromb Haemost 2006;96(6):781–788. 10.1160/TH06-05-0242.
  • Dugan G, O’Donnell L, Hanbury DB, Cline JM, Caudell DL. Assessment of Multiplate platelet aggregometry using citrate, heparin or hirudin in Rhesus macaques. Platelets 2015;26(8):730–735. 10.3109/09537104.2014.988694.
  • Sweeney JD, Hoernig LA, Michnik A, Fitzpatrick JE. Whole blood aggregometry: influence of sample collection and delay in study performance on test results. Am J Clin Pathol 1989;92(5):676–679. 10.1093/ajcp/92.5.676.
  • Yadav S, Storrie B. The cellular basis of platelet secretion: emerging structure/function relationships. Platelets 2017;28(2):108–118. 10.1080/09537104.2016.1257786.
  • Wysokinski WE,et al., Impact of atrial fibrillation on platelet gene expression. Eur J Haematol 2017;98(6):615–621. 10.1111/ejh.12879.
  • Gremmel T, Frelinger AL, Michelson AD. Platelet Physiology. Semin Thromb Hemost 2016;42(3):191–204. 10.1055/s-0035-1564835.
  • Ghoshal K, Bhattacharyya M. Overview of platelet physiology: its hemostatic and nonhemostatic role in disease pathogenesis. ScientificWorldJournal 2014;2014. 781857. 10.1155/2014/781857.
  • Hashimoto K, Narita N, Tomitaka S, Iyo M, Minabe Y. regulation of serotonin 5-HT2a receptors in rat brain by subchronic administration of σ receptor ligand NE-100. Life Sci 1997;60(24):2245–2254. 10.4103/0366-6999.226076.
  • Labos C, Dasgupta K, Nedjar H, Turecki G, Rahme E. Risk of bleeding associated with combined use of selective serotonin reuptake inhibitors and antiplatelet therapy following acute myocardial infarction. CMAJ 2011;183(16):1835–1843. 10.1503/cmaj.100912.
  • Tagashira H, Bhuiyan MS, Shioda N, Fukunaga K. Fluvoxamine rescues mitochondrial Ca2+ transport and ATP production through σ1-receptor in hypertrophic cardiomyocytes. Life Sci 2014;95(2):89–100. 10.1016/S0014-2999(97)01402-7.
  • Weng T-Y, Tsai S-YA, Su T-P. Roles of sigma-1 receptors on mitochondrial functions relevant to neurodegenerative diseases. J Biomed Sci 2017;24(1):74. 10.1186/s12929-017-0380-6.
  • Pabba M, et al., NMDA receptors are upregulated and trafficked to the plasma membrane after sigma-1 receptor activation in the rat hippocampus. J Neurosci 2014;34(34):11325–11338. 10.1523/JNEUROSCI.0458-14.2014.
  • Iñiguez MA, Punzón C, Nieto R, Burgueño J, Vela JM, Fresno M. Inhibitory effects of sigma-2 receptor agonists on T lymphocyte activation. Front Pharmacol 2013;4. 23. 10.3389/fphar.2013.00023.
  • Braun A, Vogtle T, Varga-Szabo D, Nieswandt B. STIM and Orai in hemostasis and thrombosis. Front Biosci (Landmark Ed) 2011;16(1):2144–2160. 10.2741/3844.
  • Varga-Szabo D, Braun A, Nieswandt B. Calcium signaling in platelets. J Thromb Haemost 2009;7(7):1057–1066. 10.1111/j.1538-7836.2009.03455.x.
  • Varga-Szabo D, Braun A, Nieswandt B. STIM and Orai in platelet function. Cell Calcium 2011;50(3):270–278. 10.1016/j.ceca.2011.04.002.
  • Ramström S. Arachidonic acid causes lysis of blood cells and ADP-dependent platelet activation responses in platelet function tests. Platelets 2019;30(8):1001–1007. 10.1080/09537104.2018.1557614.
  • Lin Y-H, Brown JA, DiMartino C, Dahms I, Salem Jr. N, Hibbeln JR. Differences in long chain polyunsaturates composition and metabolism in male and female rats. Prostaglandins Leukot Essent Fatty Acids 2016;113. 19–27. 10.1016/j.plefa.2016.08.008.
  • Iyer KS, Dayal S. Modulators of platelet function in aging. Platelets 2020;31(4):474–482. 10.1080/09537104.2019.1665641.
  • Koessler J, et al., Role of purinergic receptor expression and function for reduced responsiveness to adenosine diphosphate in washed human platelets. PLoS One 2016;11(1):e0147370. 10.1371/journal.pone.0147370.
  • Hardy M, et al., Effects of time-interval since blood draw and of anticoagulation on platelet testing (count, indices and impedance aggregometry): a systematic study with blood from healthy volunteers. J Clin Med 2020;9(8):E2515. 10.3390/jcm9082515.
  • Sibbing D, et al., Assessment of ADP-induced platelet aggregation with light transmission aggregometry and multiple electrode platelet aggregometry before and after clopidogrel treatment. Thromb Haemost 2008;99(1):121–126. 10.1160/TH07-07-0478.
  • Hwang DH. Characteristics of the formation of the platelet lipoxygenase product from endogenous arachidonic acid. Lipids 1982;17(12):845–847. 10.1007/BF02534576.
  • Evangelista V, et al., De novo synthesis of cyclooxygenase-1 counteracts the suppression of platelet thromboxane biosynthesis by aspirin. Circ Res 2006;98(5):593–595. 10.1161/01.RES.0000214553.37930.3e.
  • Hu Q, Cho MS, Thiagarajan P, Aung FM, Sood AK, Afshar-Kharghan V. A small amount of cyclooxygenase 2 (COX2) is constitutively expressed in platelets. Platelets 2017;28(1):99–102. 10.1080/09537104.2016.1203406.
  • Broos K, Feys HB, De Meyer SF, Vanhoorelbeke K, Deckmyn H. Platelets at work in primary hemostasis. Blood Rev 2011;25(4):155–167. 10.1016/j.blre.2011.03.002.
  • van der Meijden PEJ, Heemskerk JWM. Platelet biology and functions: new concepts and clinical perspectives. Nat Rev Cardiol 2019;16(3):166–179. 10.1038/s41569-018-0110-0.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.