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Article

Early recognition of sepsis-induced coagulopathy using the C2PAC index: a ratio of soluble type C lectin-like receptor 2 (sCLEC-2) level and platelet count

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Pages 935-944 | Received 28 Apr 2021, Accepted 18 Nov 2021, Published online: 24 Jan 2022

References

  • Vardon-Bounes F, Ruiz S, Gratacap MP, Garcia C, Payrastre B, Minville V. Platelets are critical key players in sepsis. Int J Mol Sci 2019;20(14):3494. doi:10.3390/ijms20143494
  • Yun SH, Sim EH, Goh RY, Park JI, Han JY. Platelet activation: the mechanisms and potential biomarkers. Biomed Res Int 2016;2016:9060143. doi:10.1155/2016/9060143
  • Kaur R, Kaur M, Singh J. Endothelial dysfunction and platelet hyperactivity in type 2 diabetes mellitus: molecular insights and therapeutic strategies. Cardiovasc Diabetol 2018;17(1):121. doi:10.1186/s12933-018-0763-3
  • Al-Tamimi M, Grigoriadis G, Tran H, Paul E, Servadei P, Berndt MC, Gardiner EE, Andrews RK. Coagulation-induced shedding of platelet glycoprotein VI mediated by factor Xa. Blood 2011;117(14):3912–3920. doi:10.1182/blood-2010-08-301523
  • Inoue O, Osada M, Nakamura J, Kazama F, Shirai T, Tsukiji N, Sasaki T, Yokomichi H, Dohi T, Kaneko M, et al. Soluble CLEC-2 is generated independently of ADAM10 and is increased in plasma in acute coronary syndrome: comparison with soluble GPVI. Int J Hematol 2019;110(3):285–294. doi:10.1007/s12185-019-02680-4
  • Suzuki-Inoue K, Tsukiji N, Shirai T, Osada M, Inoue O, Ozaki Y. Platelet CLEC-2: roles beyond hemostasis. Semin Thromb Hemost 2018;44(2):126–134. doi:10.1055/s-0037-1604090
  • Meng D, Luo M, Liu B. The role of CLEC-2 and Its Ligands in Thromboinflammation. Front Immunol 2021;12:688643. doi:10.3389/fimmu.2021.688643
  • Navarro-Núñez L, Langan SA, Nash GB. Watson SP.The physiological and pathophysiological roles of platelet CLEC-2. Thromb Haemost 2013;109(6):991–998. doi:10.1160/TH13-01-0060
  • Kazama F, Nakamura J, Osada M, Inoue O, Oosawa M, Tamura S, Tsukiji N, Aida K, Kawaguchi A, Takizawa S, et al. Measurement of soluble C-type lectin-like receptor 2 in human plasma. Platelets 2015;26(8):711–719. doi:10.3109/09537104.2015.1021319
  • Fei M, Xiang L, Chai X, Jin J, You T, Zhao Y, Ruan C, Hao Y, Zhu L. Plasma soluble C-type lectin-like receptor-2 is associated with the risk of coronary artery disease. Front Med 2020;14(1):81–90. doi:10.1007/s11684-019-0692-x
  • Zhang X, Zhang W, Wu X, Li H, Zhang C, Huang Z, Shi R, You T, Shi J, Cao Y. Prognostic significance of plasma CLEC-2 (C-type lectin-like receptor 2) in patients with acute ischemic stroke. Stroke 2018;7:STROKEAHA118022563
  • Nishigaki A, Ichikawa Y, Ezaki M, Yamamoto A, Suzuki K, Tachibana K, Kamon T, Horie S, Masuda J, Makino K, et al. Soluble C-type lectin-like receptor 2 elevation in patients with acute cerebral infarction. J Clin Med 2021;10(15):3408. doi:10.3390/jcm10153408
  • Guo M, Zhang H, Lv QW, Huang HB, Shen LJ. Higher plasma C-type lectin-like receptor 2 concentrations for prediction of higher risk of 30-day mortality in isolated severe blunt traumatic brain injury. Clin Chim Acta 2019;496:1–6. doi:10.1016/j.cca.2019.06.014
  • Yamashita Y, Suzuki K, Mastumoto T, Ikejiri M, Ohishi K, Katayama N, Suzuki-Inoue K, Wada H. Elevated plasma levels of soluble C-type lectin-like receptor 2 (CLEC2) in patients with thrombotic microangiopathy. Thromb Res 2019;178:54–58. doi:10.1016/j.thromres.2019.03.018
  • Yamamoto A, Wada H, Ichkawa Y, Tanaka M, Tashiro H, Shiraki K, Shimpo H, Yamashita Y, Mastumoto T, Shimaoka M, et al. Soluble C-type lectin-like receptor 2 is a biomarker for disseminated intravascular coagulation. J Clin Med 2021;10(13):2860. doi:10.3390/jcm10132860
  • Levi M, Ten Cate H. Disseminated intravascular coagulation. N Engl J Med 1999;341(8):586–592. doi:10.1056/NEJM199908193410807
  • Iba T, Levy JH. Sepsis-induced coagulopathy and disseminated intravascular coagulation. Anesthesiology 2020;132(5):1238–1245. doi:10.1097/ALN.0000000000003122
  • Saito S, Uchino S, Hayakawa M, Yamakawa K, Kudo D, Iizuka Y, Sanui M, Takimoto K, Mayumi T, Sasabuchi Y. Japan Septic Disseminated Intravascular Coagulation (JSEPTIC DIC) study group: epidemiology of disseminated intravascular coagulation in sepsis and validation of scoring systems. J Crit Care 2019;50:23–30. doi:10.1016/j.jcrc.2018.11.009
  • Asakura H, Takahashi H, Uchiyama T, Eguchi Y, Kohji Okamoto K, Kawasugi K, Madoiwa S, Wada H. DIC subcommittee of the Japanese Society on Thrombosis and Hemostasis: proposal for new diagnostic criteria for DIC from the Japanese Society on Thrombosis and Hemostasis. Thromb J 2016;14(1):42. doi:10.1186/s12959-016-0117-x
  • Asakura H, Takahashi H, Uchiyama T, Eguchi Y, Okamoto K, Kawasugi K, Madoiwa S, Wada H. DIC subcommittee of the Japanese Society on Thrombosis and Hemostasis. Classifying types of disseminated intravascular coagulation: clinical and animal models. J Intensive Care 2014;2:20. doi:10.1186/2052-0492-2-20
  • Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, et al. The third international consensus definitions for sepsis and septic shock (sepsis-3). JAMA 2016;315(8):801–810. doi:10.1001/jama.2016.0287
  • Gando S, Iba T, Eguchi Y, Ohtomo Y, Okamoto K, Koseki K, Mayumi T, Murata A, Ikeda T, Ishikura H, et al. A multicenter, prospective validation of disseminated intravascular coagulation diagnostic criteria for critically ill patients: comparing current criteria. Crit Care Med 2006;34(3):625–631. doi:10.1097/01.CCM.0000202209.42491.38
  • Taylor FB Jr, Toh CH, Hoots WK, Wada H, Levi M. Scientific subcommittee on disseminated intravascular coagulation (DIC) of the international society on thrombosis and haemostasis (ISTH). Towards definition, clinical and laboratory criteria, and a scoring system for disseminated intravascular coagulation. Thromb Haemost 2001;86(11):1327–1330. doi:10.1055/s-0037-1616068
  • Kobayashi N, Maegawa K, Takada M, Tanaka H, Gonmori H. Criteria for diagnosis of DIC based on the analysis of clinical and laboratory findings in 345 DIC patients collected by the research committee on DIC in Japan. Bibl Haematol 1987;49:265–275
  • Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med 1985;13(10):818–829. doi:10.1097/00003246-198510000-00009
  • Vincent JL, de Mendonça A, Cantraine F, Moreno R, Takala J, Suter PM, Sprung CL, Colardyn F, Blecher S. Use of the SOFA score to assess the incidence of organ dysfunction/failure in intensive care units: results of a multicenter, prospective study. Working group on “sepsis-related problems” of the European Society of Intensive Care Medicine. Crit Care Med 1998;26(11):1793–1800. doi:10.1097/00003246-199811000-00016
  • Hanley JA, McNeil BJ. The meaning and use of the area under a receiver operating characteristic (ROC) curve. Radiology 1982;143(1):29–36. doi:10.1148/radiology.143.1.7063747
  • Title of subordinate document. In: Sepsis. Global Sepsis alliance. [Cited 2021 April 25]; Available from: https://www.global-sepsis-alliance.org/sepsis
  • Middleton EA, Rowley JW, Campbell RA, Grissom CK, Brown SM, Beesley SJ, Schwertz H, Kosaka Y, Manne BK, Krauel K, et al. Sepsis alters the transcriptional and translational landscape of human and murine platelets. Blood 2019;134(12):911–923. doi:10.1182/blood.2019000067
  • Greco E, Lupia E, Bosco O, Vizio B, Montrucchio G. Platelets and multi-organ failure in sepsis. Int J Mol Sci 2017;18(10):2200. doi:10.3390/ijms18102200
  • Wang Y, Ouyang Y, Liu B, Ma X, Ding R. Platelet activation and antiplatelet therapy in sepsis: a narrative review. Thromb Res 2018;166:28–36. doi:10.1016/j.thromres.2018.04.007
  • Parikh F. Infections and thrombocytopenia. J Assoc Physicians India 2016;64(2):11–12
  • Levi M, van der Poll T. Inflammation and coagulation. Crit Care Med 2010;38(2 Suppl):S26–34
  • Trauer J, Muhi S, McBryde ES, Al Harbi SA, Arabi YM, Boyle AJ, Cartin-Ceba R, Chen W, Chen YT, Falcone M, et al. Quantifying the effects of prior acetyl-salicylic acid on sepsis-related deaths: an individual patient data meta-analysis using propensity matching. Crit Care Med 2017;45(11):1871–1879. doi:10.1097/CCM.0000000000002654