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Platelets Volume 33, 2022 - Issue 8
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Letter

Romiplostim for PARP inhibitor-induced thrombocytopenia in solid tumor malignancies

Abraham Z. CheloffDivision of Hematology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USAORCID Iconhttps://orcid.org/0000-0002-5489-4789View further author information
ORCID Icon &
Hanny Al‐SamkariDivision of Hematology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USACorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-6175-1383View further author information
ORCID Icon
Pages 1312-1313 | Received 18 Jun 2022, Accepted 19 Aug 2022, Published online: 01 Sep 2022

References

  • Slade D. PARP and PARG inhibitors in cancer treatment. Genes Dev. 2020;34(5–6):360–394. doi:10.1101/gad.334516.119.
  • United States Food and Drug Administration. Highlights of prescribing information: lunparza. Published 2014. https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/208558s014lbl.pdf.
  • González-Martín A, Pothuri B, Vergote I, DePont Christensen R, Graybill W, Mirza MR, McCormick C, Lorusso D, Hoskins P, Freyer G, et al. Niraparib in patients with newly diagnosed advanced ovarian cancer. N Engl J Med. 2019;381(25):2391–2402. doi:10.1056/NEJMoa1910962.
  • Hao J, Liu Y, Zhang T, He J, Zhao H, An R, Xue Y . Efficacy and safety of PARP inhibitors in the treatment of advanced ovarian cancer: an updated systematic review and meta-analysis of randomized controlled trials. Crit Rev Oncol Hematol. 2021;157:103145. doi:10.1016/j.critrevonc.2020.103145.
  • Soff GA, Miao Y, Bendheim G, Batista J, Mones JV, Parameswaran R, Wilkins CR, Devlin SM, Abou-Alfa GK, Cercek A, et al. Romiplostim treatment of chemotherapy-induced thrombocytopenia. J Clin Oncol. 2019;37(31):2892–2898. doi:10.1200/JCO.18.01931.
  • Al-Samkari H, Soff GA. Clinical challenges and promising therapies for chemotherapy-induced thrombocytopenia. Expert Rev Hematol. 2021;14(5):437–448. doi:10.1080/17474086.2021.1924053.
  • Al-Samkari H, Marshall AL, Goodarzi K, Kuter DJ. The use of romiplostim in treating chemotherapy-induced thrombocytopenia in patients with solid tumors. Haematologica. 2018;103(4):e169–e172. doi:10.3324/haematol.2017.180166.
  • Al-Samkari H, Parnes AD, Goodarzi K, Weitzman JI, Connors JM, Kuter DJ. A multicenter study of romiplostim for chemoherapy-induced thrombocytopenia in solid tumors and hematologic malignancies. Haematologica. 2021;106(4):1148–1157. doi:10.3324/haematol.2020.251900.
  • Gabrail N, Smith C. Avatrombopag optimizes response to niraparib by managing thrombocytopenia associated with Poly-ADP Ribose Polymerase (PARP) inhibition in ovarian cancer and breast cancer: a case series. Am J Case Rep. 2020;21:e927008. doi:10.12659/AJCR.927008.
  • Griffiths EA, Roy V, Alwan L, Bachiashvili K, Baird J, Cool R, Dinner S, Geyer M, Glaspy J, Gojo I, et al. NCCN guidelines® insights: hematopoietic growth factors, version 1.2022: featured updates to the NCCN guidelines. J Natl Compr Cancer Netw. 2022;20(5):436–442. doi:10.6004/jnccn.2022.0026.

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