Are biotechnology and its clusters in crisis?

References

• Arthur , B. , Durlauf , S. and Lane , D. 1997 . The economy as an evolving complex system , Vol. II , Reading, MA : Addison-Wesley .
   Google Scholar
• Beinhocker , E. 2007 . The origin of wealth: Evolution, complexity and the radical remaking of economics , Boston, MA : Harvard Business Press .
   Google Scholar
• Brooks , M. 2011 . Free radicals: The secret anarchy of science , London : Profile .
   Google Scholar
• Chesbrough , H. 2003 . Open innovation , Boston, MA : Harvard Business School Press .
   Google Scholar
• Coenen , L. and Moodysson , J. 2004 . Nodes, networks and proximities: On the knowledge dynamics of the Medicon Valley biotech cluster . European Planning Studies , 12 : 1003 – 18 .
   Web of Science ®Google Scholar
• Cooke , P. 2007 . Growth cultures: The global bioeconomy and its bioregions , London : Routledge .
   Google Scholar
• Cooke , P. 2012 . Complex adaptive innovation systems: Relatedness and transversality in the evolving region , London : Routledge .
   Google Scholar
• Crotty , S. 2001 . Ahead of the curve , Berkeley : University of California Press .
   Google Scholar
• Cunningham , K. and Brevold , E. 2010 . San Diego's Golf Economy , La Jolla, CA : NUS Institute for Policy Research .
   Google Scholar
• Foray, D. 2012. Lessons from the life sciences innovation system in the US. Presentation to the Master DEIN and Annual Workshop REDE REPENSel, University of Santiago de Compostela, 28 May–1 June 2012.
   Google Scholar
• Grove , A. 1996 . Only the paranoid survive , New York : Doubleday .
   Google Scholar
• Harvey , M. 2002 . “ Competition as instituted process ” . In Market relations and the competitive process , Edited by: Metcalfe , S. and Warde , A. 73 – 94 . Manchester : Manchester University Press .
   Google Scholar
• Henderson , R. and Clark , K. 1990 . Architectural innovation: The reconfiguration of existing product technologies and the failure of established firms . Administrative Science Quarterly , 35 : 9 – 30 . (doi:10.2307/2393549)
   Web of Science ®Google Scholar
• Hendrickson , M. 2011 . “ Exorcizing Schrödinger's ghost: Reflections on ‘What Is Life?’ and its surprising relevance to cancer biology ” . In What is life? The intellectual pertinence of Erwin Schrödinge , Edited by: Gumbrecht , H. , Harrison , R. , Hendrickson , M. and Laughlin , R. 45 – 104 . Stanford, CA : Stanford University Press .
   Google Scholar
• Holland , J. 1995 . Hidden order: How adaptation builds complexity , Reading, MA : Addison-Wesley .
   Google Scholar
• Jingan , W. 2010 . “ Innovation and development: A study of Yangzhou semiconductor lighting industrial cluster ” . In Report on the innovation and development of China's industrial clusters Edited by: Sujian , H. , Qin , W. and Zhiyu , S. 98 – 108 . Beijing: RUID
   Google Scholar
• Juarrero , A. and Rubino , C. 2008 . Emergence, complexity and self-organization , Goodyear, AZ : ISCE Publications .
   Google Scholar
• Kauffman , S. 1995 . At home in the universe , Oxford : Oxford University Press .
   Google Scholar
• Kauffman , S. 2008 . Reinventing the sacred , New York : Basic Books .
   Google Scholar
• Kessel , M. 2011 . The problems with today's pharmaceutical business – An outsider's view . Nature Biotechnology , 29 : 27 – 33 . (doi:10.1038/nbt.1748)
   PubMed Web of Science ®Google Scholar
• Kuhn , T. 1963 . The structure of scientific revolutions , London : Penguin .
   Google Scholar
• Lyons , D. 2000 . Embeddedness, milieu, and innovation among high-technology firms: A Richardson, Texas case study . Environment & Planning A , 32 : 891 – 908 . (doi:10.1068/a3279)
   Web of Science ®Google Scholar
• McClintock , B. 1984 . The significance of responses of the genome to challenge . Science , 226 : 792 – 801 . (doi:10.1126/science.15739260)
   PubMed Web of Science ®Google Scholar
• Mitchell , P. 2008 . US credit crunch impacts biotech across the globe . Nature Biotechnology , 26 : 359 – 60 . (doi:10.1038/nbt0408-359)
   PubMed Web of Science ®Google Scholar
• Muscio , A. 2006 . Patterns of innovation in industrial districts: An empirical analysis . Industry & Innovation , 13 : 291 – 302 . (doi:10.1080/13662710600858860)
   Google Scholar
• NSF . 2010 . Globalization of science and engineering , Washington, DC : National Science Foundation .
   Google Scholar
• Porter , M. 1998 . On competition , Boston, MA : Harvard Business School Press .
   Google Scholar
• Raymond , E. 1999 . The cathedral and the bazaar , Sebastopol, CA : O'Reilly .
   Google Scholar
• Schrödinger , E. 1943 . What is life? , Cambridge, MA : Cambridge University Press .
   Google Scholar
• Smith , G. , Akram , M. , Redpath , K. and Bains , W. 2009 . Wasting cash – The decline of the British biotech sector . Nature Biotechnology , 27 : 531 – 37 . (doi:10.1038/nbt0609-531)
   PubMed Web of Science ®Google Scholar
• Sturgeon , T. 2002 . Modular production networks: A new American model of industrial organization . Industrial and Corporate Change , 11 : 451 – 96 . (doi:10.1093/icc/11.3.451)
   Web of Science ®Google Scholar
• Whipple , T. 2012 . Gene ‘revolution’ has stalled, says Winston . The Times , 9 June : 3
   Google Scholar
• Zhang , F. , Cooke , P. and Wu , F. 2011 . State-sponsored R&D: A case study of China's biotechnology . Regional Studies , 45 : 575 – 95 . (doi:10.1080/00343401003604663)
   Web of Science ®Google Scholar