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Original Articles

Production and Characterization of Monoclonal Antibodies against Norsolorinic Acid Reductase Involved in Aflatoxin Biosynthesis

Pages 29-42 | Published online: 01 Jul 2010

References

  • BHATNAGAR , D. and CLEVELAND , T. E. 1990 . Purification and characterization of a reductase from Aspergillus parasiticus SRRC 2043 involved in aflatoxin biosynthesis . FASEB Journal , 4 : 2727
  • BHATNAGAR , D. , McCORMICK , S. P. , LEE , L. and HILL , R. A. 1987 . Identification of a-methybterigmatocystin as an aflatoxin B1 and G1 precursor in Aspergillus parasiticus . Applied and Environmental Microbiology , 53 : 1028 – 1033 .
  • BHATNAGAR , D. , ULLAH , A. H. J. and CLEVELAND , T. E. 1988 . Purification and characterization of a methyltransferase from Aspergillus parasiticus SRRC 163 involved in aflatoxin biosynthetic pathway . Preparative Biochemistry , 18 : 321 – 349 .
  • BHATNAGAR , D. , NBUCERE , J. N. and CLEVELAND , T. E. 1990 . Immunochemical detection of aflatoxigenic potential of Aspergillus species with antisera prepared against enzymes specific to aflatoxin synthesis . Food and Agricultural Immunology , 4 : 225 – 234 .
  • BHATNAGAR , D. , CLEVELAND , T. E. and KINGSTON , D. G. I. 1991a . Enzymological evidence for separate pathways for aflatoxin B1 and B2 biosynthesis . Biochemistry , 30 : 4343 – 4350 .
  • BHATNAGAR , D. , EHRLICH , K. C. and CLEVELAND , T. E. 1991b . “ Oxidation-reduction reaction in biosynthesis of secondary metabolites, in Handbook of Applied Mycology ” . In Mycotoxins in Ecological Systems , Edited by: D. , BHATNAGAR, , B. , LlLLEHOI, E. and K. , ARORA, D. Vol. V , 255 – 286 . New York : Marcel Dekker .
  • BHATNAGAR , D. , CLEVELAND , T. E. and COTTY , P. J. 1994 . Mycological aspects of aflatoxin formation, in The Toxicology of Aflatoxins: Human Health, Veterinary and Agricultural Significance , Edited by: L. , EATON, D. and D. , GROOPMAN J. 327 – 346 . New York : Academic Press .
  • BHATNAGAR , D. , PAYNE , G. , LINZ , J. E. and CLEVELAND , T. E. 1995 . Molecular biology to eliminate aflatoxins, International News on Fats . Oils and Related Materials , 6 : 262 – 271 .
  • BROWN , D. W. , Yu , J. H. , KELKAR , H. S. , FERNANDES , M. , NESBITT , T. C. , KELLER , N. P. , ADAMS , T. H. and LEONARD , T. J. 1996 . Twenty-five coregulated transcripts define a sterigmatocystin gene cluster in Aspergillus nidulans . Proceedings of the National Academy of Sciences of the United States of America , 93 : 1418 – 1422 .
  • BUCHANAN , R. L. , JONES , S. B. , GERASIMOWICZ , W. V. , ZAIKI , L. L. , STAHL , H. G. and OCKER , L. A. 1987 . Regulation of aflatoxin biosynthesis: Assessment of the role of cellular energy status as a regulator of the induction of aflatoxin production . Applied and Environmental Microbiology , 53 : 1224 – 1231 .
  • CARY , J. W. , WRIGHT , M. , BHATNAGAR , D. , LEE , R. and CHU , F. S. 1996 . Molecular characterization of Aspergillus parasiticus dehydrogenase gene, nor A, located on the aflatoxin biosynthesis gene cluster . Applied and Environmental Microbiology , 62 : 360 – 366 .
  • CHANG , P.-K. , SKORY , C. D. and LINZ , J. E . 1992 . Cloning of a gene associated with aflatoxin B1 biosynthesis in Aspergillus parasiticus . Current Genetics , 21 : 231 – 233 .
  • CHANG , P.-K. , CARY , J. W. , BHATNAGAR , D. , CLEVELAND , T. E. , BENNETT , J. W. , LINZ , J. E. , WOLOSHUK , C. P. and PAYNE , G. A. 1993 . Cloning of the Aspergillus parasiticus apa-2 gene associated with the regulation of aflatoxin biosynthesis . Applied and Environmental Microbiology , 59 : 3273 – 3279 .
  • CHANG , P.-K. , CARY , J. W. , Yu , J. , BHATNAGAR , D. and CLEVELAND , T. E. 1995a . The Aspergillus parasiticus polyketide synthase gene pksA, a homolog of Aspergillus nidulans wA, is required for aflatoxin B1 biosynthesis . Molecular and General Genetics , 248 : 270 – 277 .
  • CHANG , P.-K. , EHRLICH , K. C. , Yu , J. , BHATNAGAR , D. and CLEVELAND , T. E. 1995b . Increased expression of Aspergillus parasiticus aflR, encoding a sequence-specific DNA-binding protein, relieves nitrate inhibition of aflatoxin biosynthesis . Applied and Environmental Microbiology , 61 : 2372 – 2377 .
  • CHU , F. S. 1971 . Chromatography of crude aflatoxins on the adsorbosil-5 . Journal of the Association of Official Analytical Chemists , 54 : 1304 – 1306 .
  • CHUTURGOON , A. A. and DUTTON , M. F. 1991 . The appearance of an enzyme activity catalyzing the conversion of norsolorinic acid to averantin in Aspergillus parasiticus cultures . Mycopathologia , 113 : 41 – 44 .
  • CHUTURGOON , A. A. , DUTTON , M. F. and BERRY , R. K. 1990 . The preparation of an enzyme associated with aflatoxin biosynthesis by affinity chromatography . Biochemical and Biophysical Research Communications , 166 : 38 – 42 .
  • DUTTON , M. F. 1988 . Enzymes and aflatoxin biosynthesis . Microbiological Reviews , 52 : 274 – 295 .
  • EATON , D. L. and GROOPMAN , J. D. , eds. 1994 . The Toxicology of Aflatoxins: Human Health, Veterinary and Agricultural Significance , 544 New York : Academic Press .
  • FAN , T. S. L. , SCHUBRING , S. L. , WEI , R. D. and CHU , F. S. 1988 . Production and characterization of monoclonal antibody cross-reactivity with most group A trichothecenes . Applied and Environmental Microbiology , 54 : 2959 – 2963 .
  • FENG , G. H. and LEONARD , T. J. 1995 . Characterization of the polyketide synthase gene (pksLI) required for aflatoxin biosynthesis in Aspergillus parasiticus . Journal of Bacteriology , 177 : 6246 – 6254 .
  • FENG , G. H. , CHU , F. S. and LEONARD , T. J. 1992 . Molecular cloning of genes related to aflatoxin biosynthesis by differential screening . Applied and Environmental Microbiology , 58 : 455 – 460 .
  • HAMID , A. B. and SMITH , J. E. 1987 . Degradation of aflatoxin by Aspergillus flavus . Journal of General Microbiology , 133 : 2023 – 2029 .
  • HSIEH , D. P. H. , WAN , C. C. and BILLINGTON , J. A. 1989 . A versiconal hemiacetal acetate converting enzyme in aflatoxin biosynthesis . Mycopathologia , 107 : 121 – 126 .
  • KELLER , N. P. , DISCHINGER , H. C. JR. , BHATNAGAR , D. , CLEVELAND , T. E. and ULLAH , A. H. J. 1993 . Purification of a 40-kilodalton methyltransferase active in the aflatoxin biosynthetic pathway . Applied and Environmental Microbiology , 59 : 479 – 484 .
  • LAEMMLI , U. K. 1970 . Cleavage of structural proteins during the assembly of the head of bacteriophage T4 . Nature , 227 : 680 – 685 .
  • LEE , R. 1996 . Production and characterization of antibodies against norsolorinic acid reductase and ver-1 protein , Madison, WI, USA : University of Wisconsin-Madison . PhD Dissertation
  • LBB , R. C. , BHATNAGAR , D. , CLEVELAND , T. E. and CHU , F. S. 1995 . Production and characterization of polyclonal antibodies against norsolorinic acid reductase involved in aflatoxin biosynthesis . Food and Agricultural Immunology , 7 : 21 – 32 .
  • LIANG , S. H. , Wu , T. S. , LEE , R. , CHU , F. S. and LINZ , J. E. 1997 . Analysis of the mechanisms regulating the expression of the ver-1 gene involved in aflatoxin biosynthesis . Applied and Environmental Microbiology , 63 : 1058 – 1065 .
  • LIN , B.-K. and ANDERSON , J. A. 1992 . Purification and properties of versiconal cyclase from Aspergillus parasiticus . Archives of Biochemistry and Biophysics , 293 : 67 – 70 .
  • LIU , B. H. 1996 . Roles of a selected enzyme and a regulatory protein on aflatoxin biosynthesis , Madison, WI, USA : University of Wisconsin-Madison . PhD Dissertation
  • LIU , B. H. and CHU , F. S. 1997 . Production and characterization of monoclonal antibodies against sterigmatocystin o-methyltransferase . Food and Agricultural Immunology , 9 : 167 – 176 .
  • LIU , B. H. , KELLER , N. P. , BHATNAGAR , D. , CLEVELAND , T. E. and CHU , F. S. 1993 . Production and characterization of antibodies against sterigmatocystin o-methyltransferase . Food and Agricultural Immunology , 5 : 155 – 164 .
  • MATSUSHIMA , K.-I. , ANDO , Y. , HAMASAKI , T. and YABE , K. 1994 . Purification and characterization of two versiconal hemiacetal acetate reductases involved in aflatoxin biosynthesis . Applied and Environmental Microbiology , 60 : 2561 – 2567 .
  • Or , V. T. and HERZENBERG , L. A. 1980 . Immunoglobulin-production hybrid cell lines, in Selected Methods in Cellular Immunology , Edited by: B. , MlSHELL, B. and M. , SHIIGI, S. San Francisco : W. H. Freeman .
  • PAYNE , G. A. 1992 . Aflatoxin in maize . Critical Reviews in Plant Sciences , 10 : 423 – 440 .
  • PAYNE , G. A. , NYSTROM , G. J. , BHATNAGAR , D. , CLEVELAND , T. E. and WOLOSHUK , C. P. 1993 . Cloning of the AFL-2 gene involved in aflatoxin biosynthesis from Aspergillus flavus . Applied and Environmental Microbiology , 59 : 156 – 162 .
  • ROBENS , J. F. and RICHARD , J. L. 1992 . Aflatoxin in animal and human health . Reviews of Environmental Contamination and Toxicology , 127 : 69 – 94 .
  • SMITH , P. K. , KROHN , R. I. , HERMENSON , G. T. , MALLIA , A. K. , H , GARTNER, F. , PROVBNZANO , M. D. , FUJOMOTO , E. K. , GOEKE , N. M. , OLSON , B. J. and KLENK , D. C. 1985 . Measurement of protein using bicinchoninic acid . Analytical Biochemistry , 150 : 76 – 85 .
  • TRAIL , F. , CHANG , P.-K. , CARY , J. W. and LINZ , J. E. 1994 . Structural and functional analysis of the nor-1 gene involved in the biosynthesis of aflatoxin by Aspergillus parasiticus . Applied and Environmental Microbiology , 60 : 4078 – 4085 .
  • TRAIL , F. , MAHANTI , N. and LINZ , J. 1995a . Molecular biology of aflatoxin biosynthesis . Microbiology , 141 : 755 – 765 .
  • TRAIL , F. , MAHANTI , N. , RARICK , M. , MEHIGH , R. , LIANG , S.-H. , ZHOU , R. and LINZ , J. E. 1995b . Physical and transcriptional map of an aflatoxin gene cluster in Aspergillus parasiticus and functional disruption of a gene involved early in the aflatoxin pathway . Applied and Environmental Microbiology , 61 : 2665 – 2673 .
  • YABE , K. , NAKAMURA , Y. , NAKAJIMA , H. , ANDO , Y. and HAMASAKI , T. 1991a . Enzymatic conversion of norsolorinic acid to averufin in aflatoxin biosynthesis . Applied and Environmental Microbiology , 57 : 1340 – 1345 .
  • YABE , K. , ANDO , Y. and HAMASAKI , T. Desaturase activity in the branching step between aflatoxin Bl and G1 and aflatoxin B2 and G2 . Agricultural and Biological Chemistry , 55 1907 – 1911 .
  • Yu , J. , CARY , J. W. , BHATNAGAR , D. , CLEVELAND , T. E. , KELLER , N. P. and CHU , F. S. 1993 . Molecular cloning and characterization of an Aspergillus parasiticus gene involved in the conversion of sterigmatocystin to o-methyl-sterigmatocystin in aflatoxin biosynthesis . Applied and Environmental Microbiology , 59 : 3564 – 3571 .
  • Yu , J. H. and LEONARD , T. J. 1995 . Sterigmatocytin biosynthesis in Aspergillus nidulans requires a type I polyketide synthase . Journal of Bacteriology , 177 : 4712 – 4800 .
  • Yu , J. , CHANG , P.-K. , CARY , J. W. , WRIGHT , M. , BHATNAGAR , D. , CLEVELAND , T. E. , PAYNE , G. A. and LINZ , J. E. 1995 . Comparative mapping of aflatoxin pathway gene cluster in Aspergillus parasiticus and Aspergillus flavus . Applied and Environmental Microbiology , 61 : 2365 – 2371 .

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