Knowledge and attitudes regarding preventative HIV vaccine clinical trials in Italy: Results of a national survey

References

• Autret , E. , Dutertre , J.P. Barbier , P. 1993 . Parental opinions about biomedical research in children in Tours, France . Development in Pharmachological Therapy , 20 : 64 – 71 .
   PubMedGoogle Scholar
• Barthelow , B.N. , MacQueen , K.M. Doublas , J.M. Jr . 1997 . Assessment of the changing willingness to participate in Phase III HIV vaccine trials among men who have sex with men . Journal of Acquired Immune Deficiency Syndrome and Human Retrovirology , 16 : 108 – 115 .
   PubMedGoogle Scholar
• Buchbinder , S.P. , Metch , B. Holte , S.E. 2004 . Determinants of enrollment in a preventive HIV vaccine trial: Hypothetical versus actual willingness and barriers to participation . Journal of Acquired Immune Deficiency Syndrome , 36 : 604 – 612 .
   PubMed Web of Science ®Google Scholar
• Corbett , F. , Oldham , J. and Lilford , R. 1996 . Offering patients entry in clinical trials: Preliminary study of the views of prospective participants . Journal of Medical Ethics , 22 : 227 – 231 .
   PubMed Web of Science ®Google Scholar
• Celentano , D.D. , Beyrer , C. Natpratan , C. 1995 . Willingness to participate in AIDS vaccine trials among high-risk populations in northern Thailand . AIDS , 9 : 1079 – 1083 .
   PubMed Web of Science ®Google Scholar
• Donovan , J.L. and Blake , D.R. 1992 . Patient non-compliance: Deviance or reasoned decision-making . Social Science and Medicine , 34 ( 5 ) : 507 – 513 .
   PubMed Web of Science ®Google Scholar
• Ensoli , B. and Cafaro , A. 2000 . Novel strategies toward the development of an effective vaccine to prevent human immunodeficiency virus infection or acquired immunodeficiency virus . AIDS Clinical Review , 01 : 23 – 61 .
   Google Scholar
• Esparza , J. and Bhamarapravati , N. 2000 . Accelerating the development and future availability of HIV-1 vaccines: Why, when, where and how? . Lancet , 10 : 2061 – 2066 .
   Google Scholar
• Fallowfield , L.J. , Jenkins , V. Brennan , C. 1998 . Attitudes of patients to randomised clinical trials of cancer therapy . European Journal of Cancer , 34 ( 10 ) : 1554 – 1559 .
   PubMed Web of Science ®Google Scholar
• Fisher , W.B. , Cohen , S.J. Hammond , M.K. 1991 . Clinical trials in cancer therapy: Efforts to improve patient enrollment by community oncologists . Medical and Pediatric Oncology , 19 : 165 – 168 .
   PubMedGoogle Scholar
• Gagnon , M.P. and Godin , G. 2000 . Young adults and HIV vaccine: Determinants of the intention of getting immunized . Canadian Journal of Public Health , 91 : 432 – 434 .
   PubMed Web of Science ®Google Scholar
• Halpern , S.D. , Metzger , D.S. Berlin , J.A. 2001 . Who will enroll? Predicting participation in a Phase II AIDS vaccine trial . Journal of Acquired Immune Deficiency Syndrome , 27 : 281 – 288 .
   PubMed Web of Science ®Google Scholar
• Henzlova , M.J. , Blackburn , B.H. Bradley , E.J. 1994 . Patient perception of a long-term clinical trial: Experience using a close-out questionnaire in the Studies of Left Ventricular Dysfunction (SOLVD) trial . Controlled Clinical Trials , 15 : 284 – 293 .
   PubMedGoogle Scholar
• Hoth , D.F. , Bolognesi , D.P. Corey , L. 1994 . NIH conference. HIV vaccine development: A progress report . Annals of Internal Medicine , 121 ( 8 ) : 603 – 611 .
   PubMed Web of Science ®Google Scholar
• Hunter , C.P. , Frelick , R.W. Feldman , A.R. 1987 . Selection factors in clinical trials: Results from the Community Clinical Oncology Program Physician's Patient Log . Cancer Treatment Reports , 71 : 559 – 565 .
   PubMedGoogle Scholar
• Jenkins , R.A. , Chinaworapong , S. Morgan , P.A. 1998 . Motivation, recruitment and screening of volunteers for a Phase I/II HIV preventive vaccine trial in Thailand . Journal of Acquired Immune Deficiency Syndrome , 18 ( 2 ) : 171 – 177 .
   Web of Science ®Google Scholar
• Jenkins , R.A. , Temoshok , L.R. and Virochsiri , K. 1995 . Incentives and disincentives to participate in prophylactic HIV vaccine research . Journal of Acquired Immune Deficiency Syndrome , 9 : 36 – 42 .
   Web of Science ®Google Scholar
• Jenkins , V. and Fallowfield , L. 2000 . Reasons for accepting or declining to participate in randomized clinical trials for cancer therapy . British Journal of Cancer , 82 ( 11 ) : 1783 – 1788 .
   PubMed Web of Science ®Google Scholar
• Kiwanuka , N. , Robb , M. and Kigozi , G. 2004 . Knowledge about vaccines and willingness to participate in preventive HIV vaccine trials: A population-based study, Rakai, Uganda . Journal of Acquired Immune Deficiency Syndrome , 36 : 721 – 725 .
   PubMed Web of Science ®Google Scholar
• Koblin , B.A. , Heagerty , P. Sheon , A. 1998 . Readiness of high-risk populations in the HIV Network for Prevention Trials to participate in HIV vaccine efficacy trials in the United States . AIDS , 12 : 785 – 793 .
   PubMed Web of Science ®Google Scholar
• Koblin , B.A. , Holte , S. Lenderking , B. 2000 . Readiness for HIV vaccine trials: Changes in willingness and knowledge among high-risk populations in the HIV network for prevention trials . Journal of Acquired Immune Deficiency Syndrome , 24 ( 5 ) : 451 – 457 .
   PubMed Web of Science ®Google Scholar
• Liau , A. and Zimet , G.D. 2001 . The acceptability of HIV immunization: Examining vaccine characteristics as determining factors . AIDS Care , 13 : 643 – 650 .
   PubMed Web of Science ®Google Scholar
• MacQueen , K.M. , Buchbinder , S. Douglas , J.M. 1994 . The decision to enrol in HIV vaccine efficacy trials: Concerns elicited from gay men at increased risk for HIV infection . Journal of Acquired Immune Deficiency Syndrome , 10 : 61 – 64 .
   Google Scholar
• MacQueen , K.M. , Vanichseni , S. Kitayaporn , D. 1999 . Willingness of injection drug users to participate in an HIV vaccine efficacy trial in Bangkok, Thailand . Journal of Acquired Immune Deficiency Syndrome , 21 ( 3 ) : 243 – 251 .
   PubMed Web of Science ®Google Scholar
• Maslin , A. 1994 . A survey of the opinion on informed consent of women currently involved in clinical trials within a breast unit . European Journal of Cancer Care , 3 : 153 – 162 .
   PubMedGoogle Scholar
• McGrath , J.W. , George , K. Svilar , G. 2001 . Knowledge about vaccine trials and willingness to participate in an HIV/AIDS vaccine study in the Ugandan military . Journal of Acquired Immune Deficiency Syndrome , 27 ( 4 ) : 381 – 388 .
   PubMed Web of Science ®Google Scholar
• Orr , P.R. , Blackhurst , D.W. and Hawkins , B.S. 1992 . Patient and clinical factors predictive of missed visits and inactive status in a multi-center clinical trial . Controlled Clinical Trials , 13 : 40 – 49 .
   PubMedGoogle Scholar
• Périssé , A.R.S. , Schechter , M. Moreira , R.I. 2000 . Willingness to participate in HIV trials among men who have sex with men in Rio de Janeiro, Brazil . Journal of Acquired Immune Deficiency Syndrome , 25 : 459 – 463 .
   PubMed Web of Science ®Google Scholar
• Ross , S. , Grant , A. Counsell , C. 1999 . Barriers to participation in randomised controlled trials: A systematic review . Journal of Clinical Epidemiology , 52 ( 12 ) : 1143 – 1156 .
   PubMed Web of Science ®Google Scholar
• Slevin , M. , Mossman , J. Bowling , A. 1995 . Volunteers or victims: Patients’ views of randomized cancer clinical trials . British Journal of Cancer , 71 : 1270 – 1274 .
   PubMed Web of Science ®Google Scholar
• Strauss , R.P. , Sengupta , S. Kegeles , S. 2001 . Willingness to volunteer in future preventive HIV vaccines trials: Issues and perspectives from three US communities . Journal of Acquired Immune Deficiency Syndrome , 26 : 63 – 71 .
   PubMed Web of Science ®Google Scholar
• Taylor , K.M. 1985 . The doctor's dilemma: Physician participation in randomised clinical trials . Cancer Treatment Reports , 69 : 1095 – 1100 .
   PubMedGoogle Scholar
• Vlahov , D. , Astemborski , J. Solomon , L. 1994 . Interest in HIV vaccines among injection drug users in Baltimore, Maryland . AIDS Research and Human Retroviruses , 10 ( Suppl. 2 ) : S265 – S268 .
   PubMedGoogle Scholar
• Zimet , G.D. , Blythe , M.J. and Fortenberry , J.D. 2000 . Vaccine characteristics and acceptability of HIV immunization among adolescents . International Journal of STD & AIDS , 1 ( 3 ) : 143 – 149 .
   Google Scholar