961
Views
31
CrossRef citations to date
0
Altmetric
ART SPECIAL ARTICLES

The experience of “medicine companions” to support adherence to antiretroviral therapy: quantitative and qualitative data from a trial population in Uganda

, , , , , , , , , & show all
Pages 35-43 | Received 07 Sep 2009, Published online: 02 Aug 2010

References

  • Amuron , B. , Coutinho , A. , Grosskurth , H. , Nabiryo , C. , Birungi , J. Namara , G. 2007 . A cluster-randomised trial to compare home-based with health facility-based antiretroviral treatment in Uganda: Study design and baseline findings . Open AIDS Journal , 1 : 21 – 27 .
  • Behforouz , H.L. , Farmer , P.E. and Mukherjee , J.S. 2004 . From directly observed therapy to accompagnateurs: Enhancing AIDS treatment outcomes in Haiti and in Boston . Clinical Infectious Diseases , 38 ( s5 ) : S429 – S436 .
  • Braitstein , P. , Brinkhof , M.W. , Dabis , F. , Schechter , M. , Boulle , A. Miotti , P. 2006 . Mortality of HIV-1-infected patients in the first year of antiretroviral therapy: Comparison between low-income and high-income countries . Lancet , 367 ( 9513 ) : 817 – 824 .
  • Byakika-Tusiime , J. , Oyugi , J.H. , Tumwikirize , W.A. , Katabira , E.T. , Mugyenyi , P.N. and Bangsberg , D.R. 2005 . Adherence to HIV antiretroviral therapy in HIV+ Ugandan patients purchasing therapy . International Journal of STD & AIDS , 16 ( 1 ) : 38 – 41 .
  • Coetzee , D. , Hildebrand , K. , Boulle , A. , Maartens , G. , Louis , F. Labatala , V. 2004 . Outcomes after two years of providing antiretroviral treatment in Khayelitsha, South Africa . AIDS , 18 ( 6 ) : 887 – 895 .
  • Cox , H.S. , Morrow , M. and Deutschmann , P.W. 2008 . Long term efficacy of DOTS regimens for tuberculosis: Systematic review . British Medical Journal , 336 : 457 – 458 .
  • Davies , G.R. and Squire , S.B. 2008 . Doubts about DOTS . BMJ , 336 ( 7642 ) : 457 – 458 .
  • Etard , J.F. , Ndiaye , I. , Thierry-Mieg , M. , Gueye , N.F. , Gueye , P.M. Laniece , I. 2006 . Mortality and causes of death in adults receiving highly active antiretroviral therapy in Senegal: A 7-year cohort study . AIDS , 20 ( 8 ) : 1181 – 1189 .
  • Farmer , P. , Leandre , F. , Mukherjee , J. , Gupta , R. , Tarter , L. and Kim , J.Y. 2001 . Community-based treatment of advanced HIV disease: Introducing DOT-HAART (directly observed therapy with highly active antiretroviral therapy) . Bulletin of the World Health Organization , 79 ( 12 ) : 1145 – 1151 .
  • Ferradini , L. , Jeannin , A. , Pinoges , L. , Izopet , J. , Odhiambo , D. Mankhambo , L. 2006 . Scaling up of highly active antiretroviral therapy in a rural district of Malawi: An effectiveness assessment . Lancet , 367 ( 9519 ) : 1335 – 1342 .
  • Fielding , K.L. , Charalambous , S. , Stenson , A.L. , Pemba , L.F. , Martin , D.J. Wood , R. 2008 . Risk factors for poor virological outcome at 12 months in a workplace-based antiretroviral therapy programme in South Africa: A cohort study . BMC Infectious Diseases , 8 : 93
  • Friedland , G. , Abdool Karim , S. , Abdool Karim , Q. , Lalloo , U. , Jack , C. Gandhi , N. 2004 . Utility of tuberculosis directly observed therapy programs as sites for access to and provision of antiretroviral therapy in resource-limited countries . Clinical Infectious Diseases , 38 ( Suppl. 5 ) : S421 – S428 .
  • Hardon , A.P. , Akurut , D. , Comoro , C. , Ekezie , C. , Irunde , H.F. Gerrits , T. 2007 . Hunger, waiting time and transport costs: Time to confront challenges to ART adherence in Africa . AIDS Care , 19 ( 5 ) : 658 – 665 .
  • Jaffar , S. , Amuron , B. , Foster , S.D. , Birungi , J. , Levin , J. , Namara , G. , et al. 2009 . Rates of virological failure in patients treated in a home-based versus a facility-based HIV-care model in Jinja, southeast Uganda: A cluster-randomised equivalence trial . The Lancet , 374 9707 , 2080 2089 .
  • Karamagi , C.A.S. , Tumwine , J.K. , Tylleskar , T. and Heggenhougen , K. 2006 . Intimate partner violence against women in eastern Uganda: Implications for HIV prevention . BMC Public Health , 6 ( 1 ) : 284
  • Koenig , M.A. , Lutalo , T. , Zhao , F. , Nalugoda , F. , Wabwire-Mangen , F. Kiwanuka , N. 2003 . Domestic violence in rural Uganda: Evidence from a community-based study . Bulletin of the World Health Organization , 81 : 53 – 60 .
  • Laurent , C. , Diakhate , N. , Gueye , N.F. , Toure , M.A. , Sow , P.S. Faye , M.A. 2002 . The Senegalese government's highly active antiretroviral therapy initiative: An 18-month follow-up study . AIDS , 16 ( 10 ) : 1363 – 1370 .
  • Liechty , C. and Bangsberg , D. 2003 . Doubts about DOT: Antiretroviral therapy for resource-poor countries . AIDS , 17 ( 9 ) : 1383 – 1387 .
  • Marazzi , M.C. , Liotta , G. , Germano , P. , Guidotti , G. , Altan , A.D. Ceffa , S. 2008 . Excessive early mortality in the first year of treatment in HIV type 1-infected patients initiating antiretroviral therapy in resource-limited settings . AIDS Research and Human Retroviruses , 24 ( 4 ) : 555 – 560 .
  • Médecins sans frontières (MSF), Department of Public Health of the University of Cape Town, & The Provincial Administration of the Western Cape 2003 . Antiretroviral therapy in primary health care: Experience of the Khayelitsha Programme in South Africa . Geneva : WHO .
  • Mermin , J. , Were , W. , Ekwaru , J.P. , Moore , D. , Downing , R. Behumbiize , P. 2008 . Mortality in HIV-infected Ugandan adults receiving antiretroviral treatment and survival of their HIV-uninfected children: A prospective cohort study . Lancet , 371 ( 9614 ) : 752 – 759 .
  • Mills , E. , Nachega , J. , Bangsberg , D. , Singh , S. , Rachlis , B. Wu , P. 2006 . Adherence to HAART: A systematic review of developed and developing nation patient-reported barriers and facilitators . PLoS Medicine , 3 ( 11 ) : e438
  • Nachega , J.B. , Knowlton , A.R. , Deluca , A. , Schoeman , J.H. , Watkinson , L. Efron , A. 2006 . Treatment supporter to improve adherence to antiretroviral therapy in HIV-infected South African adults . Journal of Acquired Immune Deficiency Syndromes , 43 ( 1 ) : S127 – S133 .
  • Ssebbanja , P.K. 2007 . United against AIDS: The story of TASO , Oxford and Kampala : Strategies for Hope Trust and The AIDS Support Organization (TASO) .
  • Stringer , J.S. , Zulu , I. , Levy , J. , Stringer , E.M. , Mwango , A. Chi , B.H. 2006 . Rapid scale-up of antiretroviral therapy at primary care sites in Zambia: Feasibility and early outcomes . JAMA , 296 ( 7 ) : 782 – 793 .
  • Toure , S. , Kouadio , B. , Seyler , C. , Traore , M. , Dakoury-Dogbo , N. Duvignac , J. 2008 . Rapid scaling-up of antiretroviral therapy in 10,000 adults in Cote d'Ivoire: 2-year outcomes and determinants . AIDS , 22 ( 7 ) : 873 – 882 .
  • Vicente , M. , Hodgson , J. , Massidda , O. , Tonjum , T. , Henriques-Normark , B. and Ron , E.Z. 2006 . The fallacies of hope: Will we discover new antibiotics to combat pathogenic bacteria in time? . FEMS Microbiology Reviews , 30 ( 6 ) : 841 – 852 .
  • Wanyama , J. , Castelnuovo , B. , Wandera , B. , Mwebaze , P. , Kambugu , A. Bangsberg , D.R. 2007 . Belief in divine healing can be a barrier to antiretroviral therapy adherence in Uganda . AIDS , 21 ( 11 ) : 1486 – 1487 .
  • Ware , N.C. , Idoko , J. , Kaaya , S. , Biraro , I.A. , Wyatt , M.A. Agbaji , O. 2009 . Explaining adherence success in Sub-Saharan Africa: An ethnographic study . PLoS Medicine , 6 : e1000011
  • Whetten-Goldstein , K. , Nguyen , T.Q. and Sugarman , J. 2001 . So much for keeping secrets: The importance of considering patients' perspectives on maintaining confidentiality . AIDS Care , 13 ( 4 ) : 457 – 466 .