Concomitant herbal medicine and Antiretroviral Therapy (ART) use among HIV patients in Western Uganda: A cross-sectional analysis of magnitude and patterns of use, associated factors and impact on ART adherence

References

• Bajunirwe , F. , Arts , E.J. , Tisch , D.J. , King , C.H. , Debanne , S.M. , & Sethi , A.K. 2009 . Adherence and treatment response among HIV-1-infected adults receiving antiretroviral therapy in a rural government hospital in Southwestern Uganda . Journal of the International Association of Physicians in AIDS Care (Chic) 8 2 , 139 – 147 . doi: 10.1177/1545109709332470 .
   PubMedGoogle Scholar
• Chen , X. , Yang , L. , Zhang , N. , Turpin , J.A. , Buckheit , R.W. , Osterling , C. , Howard , O.M. 2003 . Shikonin, a component of Chinese herbal medicine, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1 . Antimicrobial Agents and Chemotherapy 47 9 , 2810 – 2816 . doi: 10.1128/aac.47.9.2810-2816.2003
   PubMed Web of Science ®Google Scholar
• Chinsembu , K.C. , & Hedimbi , M. 2010 . An ethnobotanical survey of plants used to manage HIV/AIDS opportunistic infections in Katima Mulilo, Caprivi region, Namibia . Journal of Ethnobiology and Ethnomedicine 6 , 25 . doi: 10.1186/1746-4269-6-25 .
   PubMedGoogle Scholar
• Colebunders , R. , Dreezen , C. , Florence , E. , Pelgrom , Y. , & Schrooten , W. 2003 . The use of complementary and alternative medicine by persons with HIV infection in Europe . International Journal of STD & AIDS 14 10 , 672 – 674 . doi: 10.1258/095646203322387929 .
   PubMed Web of Science ®Google Scholar
• Dhalla , S. , Chan , K.J. , Montaner , J.S. , & Hogg , R.S. 2006 . Complementary and alternative medicine use in British Columbia – a survey of HIV positive people on antiretroviral therapy . Complementary Therapies in Clinical Practice 12 4 , 242 – 248 . doi: 10.1016/j.ctcp.2006.05.002 .
   PubMedGoogle Scholar
• Furler , M.D. , Einarson , T.R. , Walmsley , S. , Millson , M. , & Bendayan , R. 2003 . Use of complementary and alternative medicine by HIV-infected outpatients in Ontario, Canada . AIDS Patient Care & STDS 17 4 , 155 – 168 . doi: 10.1089/108729103321619764 .
   PubMed Web of Science ®Google Scholar
• Gao , W.N. , Wei , D.Q. , Li , Y. , Gao , H. , Xu , W.R. , Li , A.X. , & Chou , K.C. 2007 . Agaritine and its derivatives are potential inhibitors against HIV proteases . Medicinal Chemistry 3 3 , 221 – 226 . doi: 10.2174/157340607780620644 .
   PubMed Web of Science ®Google Scholar
• Hasan , S.S. , See , C.K. , Choong , C.L. , Ahmed , S.I. , Ahmadi , K. , & Anwar , M. 2010 . Reasons, perceived efficacy, and factors associated with complementary and alternative medicine use among Malaysian patients with HIV/AIDS . Journal of Alternative and Complementary Medicine 16 11 , 1171 – 1176 . doi: 10.1089/acm.2009.0657 .
   PubMed Web of Science ®Google Scholar
• Hsiao , A.F. , Wong , M.D. , Kanouse , D.E. , Collins , R.L. , Liu , H. , Andersen , R.M. , Wenger , N.S. 2003 . Complementary and alternative medicine use and substitution for conventional therapy by HIV-infected patients . Journal of Acquired Immune Deficiency Syndromes 33 2 , 157 – 165 . doi: 10.1097/00126334-200306010-00007 .
   PubMed Web of Science ®Google Scholar
• Jernewall , N. , Zea , M.C. , Reisen , C.A. , & Poppen , P.J. 2005 . Complementary and alternative medicine and adherence to care among HIV-positive Latino gay and bisexual men . AIDS Care 17 5 , 601 – 609 . doi: 10.1080/09540120512331314295 .
   PubMed Web of Science ®Google Scholar
• Katabira , E.T. , Kamya , M.R. , Kalyesubula , I. and Namale , A. 2009 . National antiretroviral treatment guidelines for adults, adolescents, and children , 3rd ed , Kampala : STD/AIDS Control Programme, Ministry of Health (MoH) .
   Google Scholar
• Ladenheim , D. , Horn , O. , Werneke , U. , Phillpot , M. , Murungi , A. , Theobald , N. , & Orkin , C. 2008 . Potential health risks of complementary alternative medicines in HIV patients . HIV Medicine 9 8 , 653 – 659 . doi: 10.1111/j.1468-1293.2008.00610.x .
   PubMed Web of Science ®Google Scholar
• Lamorde , M. , Tabuti , J.R. , Obua , C. , Kukunda-Byobona , C. , Lanyero , H. , Byakika-Kibwika , P. , Merry , C. 2010 . Medicinal plants used by traditional medicine practitioners for the treatment of HIV/AIDS and related conditions in Uganda . Journal of Ethnopharmacology 130 1 , 43 – 53 . doi: 10.1016/j.jep.2010.04.004 .
   PubMed Web of Science ®Google Scholar
• Langlois-Klassen , D. , Kipp , W. , Jhangri , G.S. , & Rubaale , T. 2007 . Use of traditional herbal medicine by AIDS patients in Kabarole District, western Uganda . American Journal of Tropical Medicine and Hygiene 77 4 , 757 – 763 . Retrieved from http://www.ajtmh.org/cgi/content/abstract/77/4/757
   PubMed Web of Science ®Google Scholar
• Langlois-Klassen , D. , Kipp , W. , & Rubaale , T. 2008 . Who's talking? Communication between health providers and HIV-infected adults related to herbal medicine for AIDS treatment in western Uganda . Social Science & Medicine 67 1 , 165 – 176 . doi: 10.1016/j.socscimed.2008.02.027 .
   PubMed Web of Science ®Google Scholar
• Lee , L.S. , Andrade , A.S.A. , & Flexner , C. 2006 . Interactions between natural health products and antiretroviral drugs: Pharmacokinetic and pharmacodynamic effects . Clinical Infectious Diseases 43 8 , 1052 – 1059 . doi: 10.1086/507894 .
   PubMed Web of Science ®Google Scholar
• Liu , J.P. , Manheimer , E. , & Yang , M. 2005 . Herbal medicines for treating HIV infection and AIDS . Cochrane Database Systematic Reviews , 2009 3 , CD003937 . doi: 10.1002/14651858.CD003937.pub2
   Web of Science ®Google Scholar
• Ma , K. , Lee , S.S. , Chu , E.K. , Tam , D.K. , Kwong , V.S. , Ho , C.F. , Wong , K.H. 2008 . Popular use of traditional Chinese medicine in HIV patients in the HAART era . AIDS and Behaviour 12 4 , 637 – 642 . doi: 10.1007/s10461-007-9245-4 .
   PubMed Web of Science ®Google Scholar
• Mannheimer , S.B. , Mukherjee , R. , Hirschhorn , L.R. , Dougherty , J. , Celano , S.A. , Ciccarone , D. , Finkelstein , R. 2006 . The CASE adherence index: A novel method for measuring adherence to antiretroviral therapy . AIDS Care 18 7 , 853 – 861 . doi: 10.1080/09540120500465160 .
   PubMed Web of Science ®Google Scholar
• Mehendale , S. , Aung , H. , Wang , C.Z. , Tong , R. , Foo , A. , Xie , J.T. , & Yuan , C.S. 2007 . Scutellaria baicalensis and a constituent flavonoid, baicalein, attenuate ritonavir-induced gastrointestinal side-effects . Journal of Pharmacy and Pharmacology 59 11 , 1567 – 1572 . doi: 10.1211/jpp.59.11.0015 .
   PubMed Web of Science ®Google Scholar
• Owen-Smith , A. , Diclemente , R. , & Wingood , G. 2007 . Complementary and alternative medicine use decreases adherence to HAART in HIV-positive women . AIDS Care 19 5 , 589 – 593 . doi: 10.1080/09540120701203279 .
   PubMed Web of Science ®Google Scholar
• Peltzer , K. , Friend-du Preez , N. , Ramlagan , S. , Fomundam , H. and Anderson , J. 2009 . Traditional complementary and alternative medicine and antiretroviral treatment adherence among HIV patients in Kwazulu-Natal, South Africa . African Journal of Traditional Complementary and Alternative Medicine , 7 ( 2 ) : 125 – 137 .
   PubMed Web of Science ®Google Scholar
• Peltzer , K. , Preez , N.F. , Ramlagan , S. , & Fomundam , H. 2008 . Use of traditional complementary and alternative medicine for HIV patients in KwaZulu-Natal, South Africa . BMC Public Health 8 , 255 . doi: 10.1186/1471-2458-8-255 .
   Google Scholar
• Rivera , J.O. , Gonzalez-Stuart , A. , Ortiz , M. , Rodriguez , J.C. , Anaya , J.P. , & Meza , A. 2005 . Herbal product use in non-HIV and HIV-positive Hispanic patients . Journal of National Medical Association 97 12 , 1686 – 1691 . Retrieved from http://www.nmanet.org/index.php/publications_sub/jmna
   PubMedGoogle Scholar
• Uganda AIDS Commission, & UNAIDS . 2010 . United National General Assembly Special Session (UNGASS) Country Progress Report, Uganda, January 2008–December 2009 . Retrieved from http://www.aidsuganda.org/Publications/UNGASS%20RPORT%202008_2009.pdf
   Google Scholar
• Weidle , P.J. , Wamai , N. , Solberg , P. , Liechty , C. , Sendagala , S. , Were , W. , & Bunnell , R. 2006 . Adherence to antiretroviral therapy in a home-based AIDS care programme in rural Uganda . Lancet 368 9547 , 1587 – 1594 . doi: 10.1016/S0140-6736(06)69118-6 .
   PubMed Web of Science ®Google Scholar
• Wiwanitkit , V. 2003 . The use of CAM by HIV-positive patients in Thailand . Complementary Therapies in Medicine 11 1 , 39 – 41 . doi: 10.1016/S0965-2299(02)00108-5 .
   PubMed Web of Science ®Google Scholar
• World Health Organization . 2002 . WHO traditional medicine strategy 2002–2005 . Geneva : World Health Organization . Retrieved from http://whqlibdoc.who.int/hq/2002/who_edm_trm_2002.1.pdf
   Google Scholar
• World Health Organization . 2005 . National policy on traditional medicine and regulation of herbal medicines: Report of a WHO global survey . Geneva : World Health Organization . Retrieved from http://whqlibdoc.who.int/publications/2005/9241593237.pdf
   Google Scholar