Disparities in achieving and sustaining viral suppression among a large cohort of HIV-infected persons in care – Washington, DCFootnote^*

* Portions of these data were presented in poster format at the Conference on Retroviruses and Opportunistic Infections Conference in Boston, MA, in February 2014, Abstract 993.

References

• Abramowitz, S., Koenig, L. J., Chandwani, S., Orban, L., Stein, R., Lagrange, R., & Barnes, W. (2009). Characterizing social support: Global and specific social support experiences of HIV-infected youth. AIDS Patient Care and STDs, 23(5), 323–330. doi:10.1089/apc.2008.0194
   PubMed Web of Science ®Google Scholar
• Adeyemi, O. M., Livak, B., McLoyd, P., Smith, K. Y., & French, A. L. (2013). Racial/ethnic disparities in engagement in care and viral suppression in a large urban HIV clinic. Clinical Infectious Diseases, 56(10), 1512–1514. doi:10.1093/cid/cit063
   PubMed Web of Science ®Google Scholar
• Anastos, K., Gange, S. J., Lau, B., Weiser, B., Detels, R., Giorgi, J. V., … Greenblatt, R. M. (2000). Association of race and gender with HIV-1 RNA levels and immunologic progression. JAIDS Journal of Acquired Immune Deficiency Syndromes, 24(3), 218–226. doi: 10.1097/00126334-200007010-00004
   PubMed Web of Science ®Google Scholar
• Beer, L., Oster, A. M., Mattson, C. L., Skarbinski, J., & Medical Monitoring, P. (2014). Disparities in HIV transmission risk among HIV-infected black and white men who have sex with men, United States, 2009. AIDS, 28(1), 105–114. doi:10.1097/QAD.0000000000000021
   PubMed Web of Science ®Google Scholar
• Benator, D. A., Elmi, A., Rodriguez, M. D., Gale, H. B., Kan, V. L., Hoffman, H. J., … Squires, L. (2015). True durability: HIV virologic suppression in an urban clinic and implications for timing of intensive adherence efforts and viral load monitoring. Aids and Behavior, 19(4), 594–600. doi:10.1007/s10461-014-0917-6
   PubMed Web of Science ®Google Scholar
• Bouris, A., Voisin, D., Pilloton, M., Flatt, N., Eavou, R., Hampton, K., … Schneider, J. A. (2013). Project nGage: Network supported HIV care engagement for younger black men who have sex with men and transgender persons. Journal of AIDS and Clinical Research, 4. doi:10.4172/2155-6113.1000236
   PubMedGoogle Scholar
• Castel, A. D. on behalf of the DC Cohort Executive Committee. (2012). Implementation of a city-wide cohort HIV-infected persons in care in Washington DC: The DC Cohort Washington, DC, July 2012: Abstract A-452-0146-08025. Poster presentation at the XIX International AIDS Conference.
   Google Scholar
• Cohen, M. S., Chen, Y. Q., McCauley, M., Gamble, T., Hosseinipour, M. C., Kumarasamy, N., … HIV Prevention Trials Network (HPTN) 052 Study Team. (2011). Prevention of HIV-1 infection with early antiretroviral therapy. New England Journal of Medicine, 365(6), 493–505. doi:10.1056/NEJMoa1105243
   PubMed Web of Science ®Google Scholar
• Crawford, T. N., Sanderson, W. T., Breheny, P., Fleming, S. T., & Thornton, A. (2014). Impact of non-HIV related comorbidities on retention in HIV medical care: Does retention improve over time? AIDS and Behavior, 18, 617–624. doi: 10.1007/s10461-013-0524-y
   PubMed Web of Science ®Google Scholar
• District of Columbia HIV/AIDS, Hepatitis, STD, TB Administration. (2014). District of Columbia HIV/AIDS, Hepatitis, STD, and TB Administration epidemiology and surveillance report: Surveillance data through December 2012. Retrieved from http://doh.dc.gov/sites/default/files/dc/sites/doh/publication/attachments/HAHSTA20Annual20Report2014_06232015_FINAL.pdf
   Google Scholar
• Gant, Z., Bradley, H., Hu, X., Skarbinski, J., Hall, H. I., & Lansky, A. (2014). Hispanics or Latinos living with diagnosed HIV: Progress along the continuum of HIV care - United States, 2010. MMWR Morbidity Mortality Weekly Report, 63(40), 886–890.
   PubMed Web of Science ®Google Scholar
• Gardner, L. I., Giordano, T. P., Marks, G., Wilson, T. E., Craw, J. A., Drainoni, M., … Retention in Care Study Group. (2014). Enhanced personal contact with HIV patients improves retention in primary care: A randomized trial in 6 US HIV clinics. Clinical Infectious Diseases, 59(5), 725–734. doi: 10.1093/cid/ciu357
   PubMed Web of Science ®Google Scholar
• Giannattasio, A., Officioso, A., Continisio, G. I., Griso, G., Storace, C., Coppini, S., … Pisacane, A. (2011). Psychosocial issues in children and adolescents with HIV infection evaluated with a World Health Organization age-specific descriptor system. Journal of Developmental and Behavioral Pediatrics, 32(1), 52–55. doi:10.1097/DBP.0b013e3181f51907
   PubMed Web of Science ®Google Scholar
• Gifford, A. L., Bormann, J. E., Shively, M. J., Wright, B. C., Richman, D. D., & Bozzette, S. A. (2000). Predictors of self-reported adherence and plasma HIV concentrations in patients on multidrug antiretroviral regimens. JAIDS Journal of Acquired Immune Deficiency Syndromes, 23(5), 386–395. doi: 10.1097/00126334-200004150-00005
   PubMed Web of Science ®Google Scholar
• Giordano, T. P., Bartsch, G., Zhang, Y., Tedaldi, E., Absalon, J., Mannheimer, S., … MacArthur, R. D. (2010). Disparities in outcomes for African American and Latino subjects in the flexible initial retrovirus suppressive therapies (FIRST) trial. AIDS Patient Care and STDs, 24(5), 287–295. doi:10.1089/apc.2009.0332
   PubMed Web of Science ®Google Scholar
• Giordano, T. P., Hartman, C., Gifford, A. L., Backus, L. I., & Morgan, R. O. (2009). Predictors of retention in HIV care among a national cohort of US Veterans. HIV Clinical Trials, 10(5), 299–305. doi:10.1310/hct1005-299
   PubMed Web of Science ®Google Scholar
• Giordano, T. P., Visnegarwala, F., White, A. C. Jr., Troisi, C. L., Frankowski, R. F., Hartman, C. M., & Grimes, R. M. (2005). Patients referred to an urban HIV clinic frequently fail to establish care: Factors predicting failure. AIDS Care, 17(6), 773–783. doi:10.1080/09540120412331336652
   PubMed Web of Science ®Google Scholar
• Greenberg, A. E., Hays, H., Castel, A. D., Subramanian, T., Happ, L. P., Jaurretche, M., … DC Cohort Executive Committee. (2015). Development of a large urban longitudinal HIV clinical cohort using a web-based platform to merge electronically and manually abstracted data from disparate medical record systems: Technical challenges and innovative solutions. Journal of the American Medical Informatics Association. December 31, 2015. pii: ocv176. doi:10.1093/jamia/ocv176
   PubMedGoogle Scholar
• Gulick, R. M., Pilcher, C. D., Murphy, R. L., Koletar, S. L., Carlson, M., Reichman, R. C., … AIDS Clinical Trials Group (ACTG) A5095 Study Team. (2006). Three- vs four-drug antiretroviral regimens for the initial treatment of HIV-1 infection: A randomized controlled trial. JAMA: The Journal of the American Medical Association, 296(7), 769–781. doi:10.1001/jama.296.7.769
   PubMed Web of Science ®Google Scholar
• Hall, H. I., Frazier, E. L., Rhodes, P., Holtgrave, D. R., Furlow-Parmley, C., Tang, T., … Skarbinski, J. (2013). Differences in human immunodeficiency virus care and treatment among subpopulations in the United States. JAMA Internal Medicine, 173(14), 1337–1344. doi:10.1001/jamainternmed.2013.6841
   PubMed Web of Science ®Google Scholar
• Hall, H. I., Gray, K. M., Tang, T., Li, J., Shouse, L., & Mermin, J. (2012). Retention in care of adults and adolescents living with HIV in 13 US areas. JAIDS Journal of Acquired Immune Deficiency Syndromes, 60(1), 77–82. doi:10.1097/QAI.0b013e318249fe90
   PubMed Web of Science ®Google Scholar
• Hanna, D. B., Buchacz, K., Gebo, K. A., Hessol, N. A., Horberg, M. A., Jacobson, L. P., … Gange, S. J. (2013). Trends and disparities in antiretroviral therapy initiation and virologic suppression among newly treatment-eligible HIV-infected individuals in North America, 2001-2009. Clinical Infectious Diseases, 56(8), 1174–1182. doi:10.1093/cid/cit003
   PubMed Web of Science ®Google Scholar
• Hartzell, J. D., Spooner, K., Howard, R., Wegner, S., & Wortmann, G. (2007). Race and mental health diagnosis are risk factors for highly active antiretroviral therapy failure in a military cohort despite equal access to care. JAIDS Journal of Acquired Immune Deficiency Syndromes, 44(4), 411–416. doi:10.1097/QAI.0b013e31802f83a6
   PubMed Web of Science ®Google Scholar
• Higa, D. H., Marks, G., Crepaz, N., Liau, A., & Lyles, C. M. (2012). Interventions to improve retention in HIV primary care: A systematic review of U.S. studies. Current HIV/AIDS Reports, 9(4), 313–325. doi: 10.1007/s11904-012-0136-6
   PubMed Web of Science ®Google Scholar
• Hightow-Weidman, L. B., Smith, J. C., Valera, E., Matthews, D. D., & Lyons, P. (2011). Keeping them in “STYLE”: Finding, linking, and retaining young HIV-positive black and Latino men who have sex with men in care. AIDS Patient Care and STDs, 25(1), 37–45. doi:10.1089/apc.2010.0192
   PubMed Web of Science ®Google Scholar
• Howe, C. J., Napravnik, S., Cole, S. R., Kaufman, J. S., Adimora, A. A., Elston, B., … Mugavero, M. J. (2014). African American race and HIV virological suppression: Beyond disparities in clinic attendance. American Journal of Epidemiology, 179(12), 1484–1492. doi:10.1093/aje/kwu069
   PubMed Web of Science ®Google Scholar
• International Advisory Panel on HIV Care Continuum Optimization. (2015). IAPAC guidelines for optimizing the HIV care continuum for adults and adolescents. Journal of the International Association of Providers of AIDS Care. doi:2325957415613442
   Google Scholar
• Jensen-Fangel, S., Pedersen, L., Pedersen, C., Larsen, C. S., Tauris, P., Moller, A., … Obel, N. (2002). The effect of race/ethnicity on the outcome of highly active antiretroviral therapy for human immunodeficiency virus type 1-infected patients. Clinical Infectious Diseases, 35(12), 1541–1548. doi:10.1086/344769
   PubMed Web of Science ®Google Scholar
• Ko, N., Liu, H., Lai, Y., Pai, Y., & Ko, W. (2013). Case management interventions for HIV-infected individuals. Current HIV/AIDS Reports, 10(4), 390–397. doi: 10.1007/s11904-013-0183-7
   PubMed Web of Science ®Google Scholar
• Lucas, G. M., Chaisson, R. E., & Moore, R. D. (1999). Highly active antiretroviral therapy in a large urban clinic: Risk factors for virologic failure and adverse drug reactions. Annals of Internal Medicine, 131(2), 81–87. doi: 10.7326/0003-4819-131-2-199907200-00002
   PubMed Web of Science ®Google Scholar
• Lucas, G. M., Chaisson, R. E., & Moore, R. D. (2003). Survival in an urban HIV-1 clinic in the era of highly active antiretroviral therapy: A 5-year cohort study. JAIDS Journal of Acquired Immune Deficiency Syndromes, 33(3), 321–328. doi: 10.1097/00126334-200307010-00005
   PubMed Web of Science ®Google Scholar
• Maulsby, C., Millett, G., Lindsey, K., Kelley, R., Johnson, K., Montoya, D., & Holtgrave, D. (2013). A systematic review of HIV interventions for black men who have sex with men (MSM). BMC Public Health, 13, 625. doi:10.1186/1471-2458-13-625
   PubMed Web of Science ®Google Scholar
• McFall, A. M., Dowdy, D. W., Zelaya, C. E., Murphy, K., Wilson, T. E., Young, M. A., … Women’s Interagency, H. I. V. S. (2013). Understanding the disparity: Predictors of virologic failure in women using highly active antiretroviral therapy vary by race and/or ethnicity. JAIDS Journal of Acquired Immune Deficiency Syndromes, 64(3), 289–298. doi:10.1097/QAI.0b013e3182a095e9
   PubMed Web of Science ®Google Scholar
• Mugavero, M. J., Lin, H. Y., Allison, J. J., Giordano, T. P., Willig, J. H., Raper, J. L., Wray, N. P., … Saag, M. S. (2009). Racial disparities in HIV virologic failure: Do missed visits matter? JAIDS Journal of Acquired Immune Deficiency Syndromes, 50(1), 100-108. doi:10.1097/QAI.0b013e31818d5c37
   PubMed Web of Science ®Google Scholar
• Muthulingam, D., Chin, J., Hsu, L., Scheer, S., & Schwarcz, S. (2013). Disparities in engagement in care and viral suppression among persons with HIV. JAIDS Journal of Acquired Immune Deficiency Syndromes, 63(1), 112–119. doi:10.1097/QAI.0b013e3182894555
   PubMed Web of Science ®Google Scholar
• Olatosi, B. A., Probst, J. C., Stoskopf, C. H., Martin, A. B., & Duffus, W. A. (2009). Patterns of engagement in care by HIV-infected adults: South Carolina, 2004-2006. AIDS, 23(6), 725–730. doi:10.1097/QAD.0b013e328326f546
   PubMed Web of Science ®Google Scholar
• Panel on Antiretroviral Guidelines for Adults and Adolescents. (2014). Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services. Washington, DC.
   Google Scholar
• Pence, B. W., Ostermann, J., Kumar, V., Whetten, K., Thielman, N., & Mugavero, M. J. (2008). The influence of psychosocial characteristics and race/ethnicity on the use, duration, and success of antiretroviral therapy. JAIDS Journal of Acquired Immune Deficiency Syndromes, 47(2), 194–201. doi:10.1097/QAI.0b013e31815ace7e
   PubMed Web of Science ®Google Scholar
• Pyne, J. M., Fortney, J. C., Curran, G. M., Tripathi, S., Atkinson, J. H., Kilbourne, A. M., … Gifford, A. L. (2011). Effectiveness of collaborative care for depression in human immunodeficiency virus clinics. Archives of Internal Medicine, 171(1), 23–31.
   PubMedGoogle Scholar
• Reisner, S. L., Mimiaga, M. J., Skeer, M., Perkovich, B., Johnson, C. V., & Safren, S. A. (2009). A review of HIV antiretroviral adherence and intervention studies among HIV-infected youth. Topics in HIV Medicines, 17(1), 14–25.
   PubMedGoogle Scholar
• Safren, S. A., O’Cleirigh, C., Tan, J. Y., Raminani, S. R., Reilly, L. C., Otto, M. W., & Mayer, K. H. (2009). A randomized controlled trial of cognitive behavioral therapy for adherence and depression (CBT-AD) in HIV-infected individuals. Health Psychology, 28(1), 1–10. doi: 10.1037/a0012715
   PubMed Web of Science ®Google Scholar
• Saha, S., Korthuis, P. T., Cohn, J. A., Sharp, V. L., Moore, R. D., & Beach, M. C. (2013). Primary care provider cultural competence and racial disparities in HIV care and outcomes. Journal of General Internal Medicine, 28(5), 622–629. doi:10.1007/s11606-012-2298-8
   PubMed Web of Science ®Google Scholar
• Schackman, B. R., Ribaudo, H. J., Krambrink, A., Hughes, V., Kuritzkes, D. R., & Gulick, R. M. (2007). Racial differences in virologic failure associated with adherence and quality of life on efavirenz-containing regimens for initial HIV therapy: Results of ACTG A5095. JAIDS Journal of Acquired Immune Deficiency Syndromes, 46(5), 547–554. doi:10.1097/QAI.0b013e31815ac499
   PubMed Web of Science ®Google Scholar
• Silverberg, M. J., Wegner, S. A., Milazzo, M. J., McKaig, R. G., Williams, C. F., Agan, B. K., … Tri-Service AIDS Clinical Consortium Natural History Study Group. (2006). Effectiveness of highly-active antiretroviral therapy by race/ethnicity. AIDS, 20(11), 1531–1538. doi:10.1097/01.aids.0000237369.41617
   PubMed Web of Science ®Google Scholar
• Sin, N. L., & DiMatteo, M. R. (2014). Depression treatment enhances adherence to antiretroviral therapy: A meta-analysis. Annals of Behavioral Medicine, 47(3), 259–269. doi: 10.1007/s12160-013-9559-6
   PubMed Web of Science ®Google Scholar
• Terzian, A. S., Bodach, S. D., Wiewel, E. W., Sepkowitz, K., Bernard, M.-A., Braunstein, S. L., & Shepard, C. W. (2012). Novel use of surveillance data to detect HIV-infected persons with sustained high viral load and durable virologic suppression in New York City. Plos One, 7(1), e29679. doi:10.1371/journal.pone.0029679
   PubMed Web of Science ®Google Scholar
• Thompson, M. A., Mugavero, M. J., Amico, K. R., Cargill, V. A., Chang, L. W., Gross, R., … Nachega, J. B. (2012). Guidelines for improving entry into and retention in care and antiretroviral adherence for persons with HIV: Evidence-based recommendations from an international association of physicians in AIDS care panel. Annals of Internal Medicine, 156(11), 817–833. doi: 10.7326/0003-4819-156-11-201206050-00419
   PubMed Web of Science ®Google Scholar
• Torian, L. V., & Wiewel, E. W. (2011). Continuity of HIV-related medical care, New York City, 2005-2009: Do patients who initiate care stay in care? AIDS Patient Care and STDs, 25(2), 79–88. doi:http://dx.doi.org/10.1089/apc.2010.0151
   PubMed Web of Science ®Google Scholar
• United States Centers for Disease Control and Prevention. (2014a). Vital signs: HIV diagnosis, care, and treatment among persons living with HIV – United States, 2011. MMWR Morbidity Mortality Weekly Report, 63(47), 1113–1117.
   PubMed Web of Science ®Google Scholar
• United States Centers for Disease Control and Prevention. (2014b). Monitoring selected national HIV prevention and care objectives by using HIV surveillance data—United States and 6 dependent areas—2012 (Vol. 19). Atlanta, GA: Centers for Disease Control and Prevention.
   Google Scholar
• United States Department of Health and Human Services. (2015). DHHS Common Core Indicators. Retrieved March 12, 2015, from https://www.aids.gov/pdf/hhs-common-hiv-indicators.pdf
   Google Scholar
• United States Office of National AIDS Policy. (2010). National HIV/AIDS strategy: Federal implementation plan. 2010. Washington, DC: White House Office of National AIDS Policy.
   Google Scholar
• Whiteside, Y. O., Cohen, S. M., Bradley, H., Skarbinski, J., Hall, H. I., Lansky, A., … Centers for Disease Control and Prevention. (2014). Progress along the continuum of HIV care among blacks with diagnosed HIV- United States, 2010. MMWR Morbidity Mortality Weekly Report, 63(5), 85–89.
   PubMed Web of Science ®Google Scholar
• Williams, P. L., Storm, D., Montepiedra, G., Nichols, S., Kammerer, B., Sirois, P. A., … Pediatric AIDS Clinical Trials Group (PACTG) 219C Team. (2006). Predictors of adherence to antiretroviral medications in children and adolescents with HIV infection. Pediatrics, 118(6), e1745–e1757. doi:10.1542/peds.2006-0493
   Google Scholar
• Yehia, B. R., Fleishman, J. A., Metlay, J. P., Moore, R. D., & Gebo, K. A. (2012). Sustained viral suppression in HIV-infected patients receiving antiretroviral therapy. JAMA, 308(4), 339–342. doi:10.1001/jama.2012.5927
   PubMed Web of Science ®Google Scholar
• Yehia, B. R., Rebeiro, P., Althoff, K. N., Agwu, A. L., Horberg, M. A., Samji, H., … North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD). (2015). Impact of age on retention in care and viral suppression. JAIDS Journal of Acquired Immune Deficiency Syndromes, 68(4), 413–419. doi:10.1097/QAI.0000000000000489
   PubMed Web of Science ®Google Scholar
• Zanoni, B. C., & Mayer, K. H. (2014). The adolescent and young adult HIV cascade of care in the United States: Exaggerated health disparities. AIDS Patient Care and STDs, 28(3), 128–135. doi:10.1089/apc.2013.0345
   PubMed Web of Science ®Google Scholar