Publication Cover
AIDS Care
Psychological and Socio-medical Aspects of AIDS/HIV
Volume 30, 2018 - Issue 7
199
Views
0
CrossRef citations to date
0
Altmetric
Articles

Social and behavioral factors associated with failing second-line ART – results from a cohort study at the Themba Lethu Clinic, Johannesburg, South Africa

ORCID Icon, , , , , , & show all
Pages 863-870 | Received 19 Mar 2017, Accepted 07 Nov 2017, Published online: 21 Feb 2018

References

  • Ajose, O., Mookerjee, S., Mills, E. J., Boulle, A., & Ford, N. (2012). Treatment outcomes of patients on second-line antiretroviral therapy in resource-limited settings: A systematic review and meta-analysis. AIDS (london, England), 26(8), 929–938. doi: 10.1097/QAD.0b013e328351f5b2
  • Boyd, M. A., Moore, C. L., Molina, J. M., Wood, R., Madero, J. S., Wolff, M., … Cooper, D. A. (2015). SECOND-LINE study group. Baseline HIV-1 resistance, virological outcomes, and emergent resistance in the SECOND-LINE trial: An exploratory analysis. The Lancet HIV, 2(2), e42–e51. doi: 10.1016/S2352-3018(14)00061-7
  • Court, L. R., Stewart, A., Sunpath, H., Murphy, R., Winternheimer, P., Ally, M., & Maartens, G. (2014). Short term adherence tool predicts failure on second line protease inhibitor-based antiretroviral therapy: An observational cohort study. BMC Infectious Diseases, 14(1), 664. doi: 10.1186/s12879-014-0664-3
  • Cox, V. (2015). Addressing treatment failure amongst adults on second line antiretroviral therapy in Khayelitsha. 7th South African AIDS conference, Durban, South Africa, June 2015.
  • Department of Health, Republic of South Africa. The South African Antiretroviral treatment guidelines 2013. Retrieved from http://www.kznhealth.gov.za/medicine/2013_ART_Guidelines.pdf
  • Department of Health, Republic of South Africa. The South African Antiretroviral treatment guidelines 2010. Retrieved from http://www.uj.ac.za/EN/CorporateServices/ioha/Documentation/Documents/ART%20Guideline.pdf
  • Evans, D., Berhanu, R., Moyo, F., Nguweneza, A., Long, L., & Fox, M. P. (2016). Can short term use of electronic patient adherence monitoring devices improve adherence in patients failing second-line ART therapy? Evidence from a pilot study in Johannesburg, South Africa. AIDS and Behavior, 20(11), 2717–2728. doi: 10.1007/s10461-016-1417-7
  • Fox, M. P., Brennan, A., Maskew, M., MacPhail, P., & Sanne, I. (2010). Using vital registration data to update mortality among patients lost to follow-up from ART programmes: Evidence from the Themba Lethu Clinic, South Africa. Tropical Medicine & International Health, 15(4), 405–413.
  • Fox, M. P., Evans, D., Steegen, K., Firnhaber, C., Ive, P., Spencer, D., … Berhanu, R. (2016). Intensive adherence counselling for HIV-infected individuals failing second-line ART in Johannesburg, South Africa. Tropical Medicine and International Health, 21, 1131–1137. doi: 10.1111/tmi.12741
  • Fox, M. P., Ive, P., Long, L., Maskew, M., & Sanne, I. (2010). High rates of survival, immune reconstitution, and virologic suppression on second-line antiretroviral therapy in South Africa. JAIDS Journal of Acquired Immune Deficiency Syndromes, 53(4), 500–506. doi: 10.1097/QAI.0b013e3181bcdac1
  • Fox, M. P., Maskew, M., MacPhail, A. P., Long, L., Brennan, A. T., & Westreich, D. (2013). Cohort profile: The Themba Lethu Clinical Cohort, Johannesburg, South Africa. International Journal of Epidemiology, 42(2), 430–439. doi: 10.1093/ije/dys029
  • Garone, D. B., Conradie, K., Patten, G., Cornell, M., Goemaere, W., & Kunene, J. (2013). High rate of virological re-suppression among patients failing second-line antiretroviral therapy following enhanced adherence support: A model of care in Khayelitsha, South Africa. Southern African Journal of HIV Medicine, 14(4), 166–169. doi: 10.4102/sajhivmed.v14i4.52
  • Johnston, V. C. K., Wiesner, L., Morris, L., Ledwaba, J., Fielding K, L., & Charalambous, S. (2014). Viral suppression following switch to second-line antiretroviral therapy: Associations with nucleoside reverse transcriptase inhibitor resistance and subtherapeutic drug concentrations prior to switch. The Journal of Infectious Diseases, 209(5), 711–720. doi: 10.1093/infdis/jit411
  • Khan, S., Das, M., Andries, A., Deshpande, A., Mansoor, H., & Saranchuk, P. (2014). Second-line failure and first experience with third-line antiretroviral therapy in Mumbai, India. Global Health Action, 7. doi: 10.3402/gha.v7.24861
  • Kiguba, R. B.-T. J., Karamagi, C., Ssali, F., Mugyenyi, P., & Katabira, E. (2007). Discontinuation and modification of highly active antiretroviral therapy in HIV-infected Ugandans prevalence and associated factors. JAIDS Journal of Acquired Immune Deficiency Syndromes, 45, 218–223. doi: 10.1097/QAI.0b013e31805d8ae3
  • Langebeek, N., Gisolf, E., Reiss, P., Vervoort, S., Hafsteinsdottir, T., & Richter, C. (2014). Predictors and correlates of adherence to combination antiretroviral therapy (ART) for chronic HIV infection: A meta-analysis. BMC Medicine, 12(1), e438. doi: 10.1186/s12916-014-0142-1
  • Levison, J. H. O., Losina, C., Lu, E., Freedberg, Z., & Wood, K. A. R. (2011). Early outcomes and the virological effect of delayed treatment switching to second-line therapy in an antiretroviral roll-out programme in South Africa. Antiviral Therapy, 16(6), 853–861. doi: 10.3851/IMP1819
  • Lima, V., Harrigan, R, Murray, M, Moore, D, Wood, E, Hogg, R, & Montaner,, J. (2008). Differential impact of adherence on long-term treatment response among naive HIV-infected individuals. AIDS (London, England), 22, 2371–2380. doi: 10.1097/QAD.0b013e328315cdd3
  • Marconi, V. C., Wu, B., Hampton, J., Ordonez, C. E., Johnson, B. A., & Singh, D. (2013). Early warning indicators for first-line virologic failure independent of adherence measures in a South African urban clinic. AIDS Patient Care and STDs, 27(12), 657–668. doi: 10.1089/apc.2013.0263
  • Martin, M., Del Cacho, E., Codina, C., Tuset, M., De Lazzari, E., Mallolas, J.,… Ribas, J. (2008). Relationship between adherence level, type of the antiretroviral regimen, and plasma HIV type 1 RNA viral load: A prospective cohort study. AIDS Research and Human Retroviruses, 24(10), 1263–1268. doi: 10.1089/aid.2008.0141
  • Mills, E., Foster, B. C., van Heeswijk, R., Phillips, E., Wilson, K., & Leonard, B. (2005). Impact of African herbal medicines on antiretroviral metabolism. AIDS (london, England), 19(1), 95–97. doi: 10.1097/00002030-200501030-00013
  • Ndahimana, J. D., Riedel, D. J., Muhayimpundu, R., Nsanzimana, S., Niyibizi, G., Mutaganzwa, E., … Redfield, R. R. (2016). HIV drug resistance mutations among patients failing second-line antiretroviral therapy in Rwanda. Antiviral Therapy, 21(3), 253–259.
  • Onoya, D., Brennan, A., Berhanu, R., van der Berg, L., Buthelezi, T., & Fox, M. P. 2016. Changes in second-line regimen durability and continuity of care in relation to national ART guideline changes in South Africa. Journal of the International AIDS Society, 19, 20675. doi: 10.7448/IAS.19.1.20675
  • Peltzer, K., Preez, N.-d., Ramlagan, S., Fomundam, H., Anderson, J., & Chanetsa, L. (2011). Antiretrovirals and the use of traditional, complementary and alternative medicine by HIV patients in Kwazulu-Natal, South Africa: A longitudinal study. African Journal of Traditional, Complementary, and Alternative Medicines, 8(4), 337–345. doi: 10.4314/ajtcam.v8i4.1
  • Shearer, K., Maskew, M., Ajayi, T., Berhanu, R., Majuba, P., & Sanne, I. (2014). Incidence and predictors of herpes zoster among antiretroviral therapy-naive patients initiating HIV treatment in Johannesburg, South Africa. International Journal of Infectious Diseases, 23, 56–62. doi: 10.1016/j.ijid.2013.10.016
  • Wood, S. A., Tobias, C., & McCree, J. (2004). Medication adherence for HIV positive women caring for children: In their own words. AIDS Care, 16, 909–913. doi: 10.1080/09540120412331290158

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.