An expanded HIV screening strategy in the Emergency Department fails to identify most patients with undiagnosed infection: insights from a blinded serosurvey

References

• Branson, B. M., Handsfield, H. H., Lampe, M. A., Janssen, R. S., Taylor, A. W., Lyss, S. B., … Centers for Disease Control and Prevention. (2006). Revised recommendations for HIV testing of adults, adolescents, and pregnant women in health-care settings. MMWR. Recommendations and Reports, 55(RR-14), 1–17; quiz CE11-14.
   PubMedGoogle Scholar
• Calderon, Y., Leider, J., Hailpern, S., Chin, R., Ghosh, R., Fettig, J., … Bauman, L. (2009). High-volume rapid HIV testing in an Urban Emergency Department. AIDS Patient Care and STDs, 23(9), 749–755. doi: 10.1089/apc.2008.0270
   PubMed Web of Science ®Google Scholar
• CDC. (2006). Missed opportunities for earlier diagnosis of HIV infection–South Carolina, 1997–2005. MMWR. Morbidity and Mortality Weekly Report, 55(47), 1269–1272.
   PubMedGoogle Scholar
• Centers for Disease Control and Prevention (CDC). (n.d.). State HIV laws. Retrieved from https://www.cdc.gov/hiv/policies/law/states/index.html
   Google Scholar
• Chadborn, T. R., Delpech, V. C., Sabin, C. A., Sinka, K., & Evans, B. G. (2006). The late diagnosis and consequent short-term mortality of HIV-infected heterosexuals (England and Wales, 2000–2004). Aids (London, England), 20(18), 2371–2379. doi: 10.1097/QAD.0b013e32801138f7
   PubMed Web of Science ®Google Scholar
• Czarnogorski, M., Brown, J., Lee, V., Oben, J., Kuo, I., Stern, R., & Simon, G. (2011). The prevalence of undiagnosed HIV infection in those who decline HIV screening in an Urban Emergency Department. AIDS Research and Treatment, 2011, 879065. doi: 10.1155/2011/879065
   PubMedGoogle Scholar
• Felsen, U. R., Cunningham, C. O., & Zingman, B. S. (2016). Increased HIV testing among hospitalized patients who declined testing in the emergency department. AIDS Care, 28(5), 591–597. doi: 10.1080/09540121.2015.1120268
   PubMed Web of Science ®Google Scholar
• Goggin, M. A., Davidson, A. J., Cantril, S. V., O’Keefe, L. K., & Douglas, J. M. (2000). The extent of undiagnosed HIV infection among emergency department patients: Results of a blinded seroprevalence survey and a pilot HIV testing program. The Journal of Emergency Medicine, 19(1), 13–19. doi: 10.1016/S0736-4679(00)00175-X
   PubMed Web of Science ®Google Scholar
• Hankin, A., Freiman, H., Copeland, B., Travis, N., & Shah, B. (2016). A Comparison of parallel and integrated models for implementation of routine HIV screening in a large, Urban Emergency Department. Public Health Reports, 131(Suppl. 1), 90–95. doi: 10.1177/00333549161310S111
   PubMedGoogle Scholar
• Haukoos, J. S., Hopkins, E., Conroy, A. A., Silverman, M., Byyny, R. L., Eisert, S., … Heffelfinger, J. D. (2010). Routine opt-out rapid HIV screening and detection of HIV infection in emergency department patients. JAMA, 304(3), 284–292. doi: 10.1001/jama.2010.953
   PubMed Web of Science ®Google Scholar
• Haukoos, J. S., Lyons, M. S., White, D. A., Hsieh, Y. H., & Rothman, R. E. (2014). Acute HIV infection and Implications of fourth-generation HIV screening in emergency departments. Annals of Emergency Medicine, 64(5), 547–551. doi: 10.1016/j.annemergmed.2014.07.004
   PubMed Web of Science ®Google Scholar
• Hsieh, Y. H., Gauvey-Kern, M., Peterson, S., Woodfield, A., Deruggiero, K., Gaydos, C. A., & Rothman, R. E. (2014). An emergency department registration kiosk can increase HIV screening in high risk patients. Journal of Telemedicine and Telecare, 20(8), 454–459. doi: 10.1177/1357633X14555637
   PubMed Web of Science ®Google Scholar
• Hsieh, Y. H., Kelen, G. D., Beck, K. J., Kraus, C. K., Shahan, J. B., Laeyendecker, O. B., … Rothman, R. E. (2016). Evaluation of hidden HIV infections in an urban ED with a rapid HIV screening program. The American Journal of Emergency Medicine, 34(2), 180–184. doi: 10.1016/j.ajem.2015.10.002
   PubMed Web of Science ®Google Scholar
• Liddicoat, R. V., Horton, N. J., Urban, R., Maier, E., Christiansen, D., & Samet, J. H. (2004). Assessing missed opportunities for HIV testing in medical settings. Journal of General Internal Medicine, 19(4), 349–356. doi: 10.1111/j.1525-1497.2004.21251.x
   PubMed Web of Science ®Google Scholar
• Lyons, M. S., Lindsell, C. J., Ruffner, A. H., Wayne, D. B., Hart, K. W., Sperling, M. I., … Fichtenbaum, C. J. (2013). Randomized comparison of universal and targeted HIV screening in the emergency department. JAIDS Journal of Acquired Immune Deficiency Syndromes, 64(3), 315–323. doi: 10.1097/QAI.0b013e3182a21611
   PubMed Web of Science ®Google Scholar
• Montoy, J. C., Dow, W. H., & Kaplan, B. C. (2016). Patient choice in opt-in, active choice, and opt-out HIV screening: Randomized clinical trial. BMJ, 352, h6895. doi: 10.1136/bmj.h6895
   Google Scholar
• New York City Department of Health and Mental Hygiene. (2017). New York city HIV/AIDS annual surveillance statistics. Retrieved from http://www1.nyc.gov/site/doh/data/data-sets/hiv-aids-annual-surveillance-statistics.page
   Google Scholar
• New York State Department of Health. (n.d.). Frequently asked questions regarding the HIV testing law. Retrieved from https://www.health.ny.gov/diseases/aids/providers/testing/law/faqs.htm
   Google Scholar
• Palella, F. J. Jr., Deloria-Knoll, M., Chmiel, J. S., Moorman, A. C., Wood, K. C., Greenberg, A. E., … Investigators, HIV Outpatient Study Investigators. (2003). Survival benefit of initiating antiretroviral therapy in HIV-infected persons in different CD4+ cell strata. Annals of Internal Medicine, 138(8), 620–626. doi: 10.7326/0003-4819-138-8-200304150-00007
   PubMed Web of Science ®Google Scholar
• Signer, D., Peterson, S., Hsieh, Y. H., Haider, S., Saheed, M., Neira, P., … Rothman, R. E. (2016). Scaling Up HIV testing in an Academic Emergency Department: An integrated testing model with rapid fourth-generation and point-of-care testing. Public Health Reports, 131(Suppl. 1), 82–89. doi: 10.1177/00333549161310S110
   PubMedGoogle Scholar
• Torian, L. V., Felsen, U. R., Xia, Q., Laraque, F., Rude, E. J., Rose, H., … Zingman, B. S. (2018). Undiagnosed HIV and HCV infection in a New York City Emergency Department, 2015. American Journal of Public Health, 108(5), 652–658. doi: 10.2105/AJPH.2018.304321
   PubMed Web of Science ®Google Scholar
• Trepka, M. J., Davidson, A. J., & Douglas, J. M. Jr. (1996). Extent of undiagnosed HIV infection in hospitalized patients: Assessment by linkage of seroprevalence and surveillance methods. American Journal of Preventive Medicine, 12(3), 195–202. doi: 10.1016/S0749-3797(18)30341-6
   PubMed Web of Science ®Google Scholar
• Walensky, R. P., Reichmann, W. M., Arbelaez, C., Wright, E., Katz, J. N., Seage, G. R., … Losina, E. (2011). Counselor- versus provider-based HIV screening in the emergency department: Results from the universal screening for HIV infection in the emergency room (USHER) randomized controlled trial. Annals of Emergency Medicine, 58(1 Suppl. 1), S126–S132.e4. doi: 10.1016/j.annemergmed.2011.03.023
   PubMed Web of Science ®Google Scholar
• White, D. A., Scribner, A. N., & Huang, J. V. (2009). A comparison of patient acceptance of fingerstick whole blood and oral fluid rapid HIV screening in an emergency department. JAIDS Journal of Acquired Immune Deficiency Syndromes, 52(1), 75–78. doi: 10.1097/QAI.0b013e3181afd33d
   PubMed Web of Science ®Google Scholar
• White, D. A., Warren, O. U., Scribner, A. N., & Frazee, B. W. (2009). Missed opportunities for earlier HIV diagnosis in an emergency department despite an HIV screening program. AIDS Patient Care and STDs, 23(4), 245–250. doi: 10.1089/apc.2008.0198
   PubMed Web of Science ®Google Scholar