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AIDS Care
Psychological and Socio-medical Aspects of AIDS/HIV
Volume 32, 2020 - Issue 10
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Articles

Does switching from multiple to single-tablet regimen containing the same antiretroviral drugs improve adherence? A group-based trajectory modeling analysis

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Pages 1268-1276 | Received 30 Jul 2019, Accepted 29 Jan 2020, Published online: 08 Mar 2020

References

  • Airoldi, M., Zaccarelli, M., Bisi, L., Bini, T., Antinori, A., Mussini, C., & Bai, F. (2010). One-pill once-a-day HAART: A simplification strategy that improves adherence and quality of life of HIV-infected subjects. Patient Preference and Adherence, 4, 115–125. https://doi.org/10.2147/PPA.S10330
  • Berg, K. M., & Arnsten, J. H. (2006). Practical and conceptual challenges in measuring antiretroviral adherence. JAIDS Journal of Acquired Immune Deficiency Syndromes, 43(Suppl 1), S79–S87. https://doi.org/10.1097/01.qai.0000248337.97814.66
  • Bezabhe, W. M., Chalmers, L., Bereznicki, L. R., & Peterson, G. M. (2016). Adherence to antiretroviral therapy and virologic failure: A meta-analysis. Medicine (Baltimore), 95(15). Article e3361. https://doi.org/10.1097/MD.0000000000003361
  • Boussari, O., Subtil, F., Genolini, C., Bastard, M., Iwaz, J., Fonton, N., Etard, J.-F., & Ecochard, R. (2015). Impact of variability in adherence to HIV antiretroviral therapy on the immunovirological response and mortality. BMC Medical Research Methodology, 15, 10. https://doi.org/10.1186/1471-2288-15-10
  • Brazilian Ministry of Health. (2015). Protocolo Clínico e Diretrizes Terapêuticas para manejo da infecção pelo HIV em adultos.
  • Brazilian Ministry of Health. (2017a). Guia de Vigilância em Saúde.
  • Brazilian Ministry of Health. (2017b). Relatório de Monitoramento Clínico do HIV.
  • Centers for Disease Control and Prevention. (2015). Calculating proportion of days covered (pdc) for antihypertensive and antidiabetic medications: An evaluation guide for grantees.
  • Chen, Y., Chen, K., & Kalichman, S. C. (2017). Barriers to HIV medication adherence as a function of regimen simplification. Annals of Behavioral Medicine, 51(1), 67–78. https://doi.org/10.1007/s12160-016-9827-3
  • DeJesus, E., Ruane, P., McDonald, C., Garcia, F., Sharma, S., Corales, R., Ravishankar, J., Khanlou, H., Shamblaw, D., Ecker, J., Ebrahimi, R., & Flaherty, J. (2008). Impact of switching virologically suppressed, HIV-1-infected patients from twice-daily fixed-dose zidovudine/lamivudine to once-daily fixed-dose tenofovir disoproxil fumarate/emtricitabine. HIV Clinical Trials, 9(2), 103–114. https://doi.org/10.1310/hct0902-103
  • Fielden, S. J., Rusch, M. L. A., Yip, B., Wood, E., Shannon, K., Levy, A. R., Montaner, J. S. G., & Hogg, R. S. (2008). Nonadherence increases the risk of hospitalization among HIV-infected antiretroviral Naïve patients started on HAART. Journal of the International Association of Physicians in AIDS Care, 7(5), 238–244. https://doi.org/10.1177/1545109708323132
  • Franklin, J. M., Krumme, A. A., Tong, A. Y., Shrank, W. H., Matlin, O. S., Brennan, T. A., & Choudhry, N. K. (2015). Association between trajectories of statin adherence and subsequent cardiovascular events. Pharmacoepidemiology and Drug Safety, 24(10), 1105–1113. https://doi.org/10.1002/pds.3787
  • Franklin, J. M., Shrank, W. H., Pakes, J., Sanfelix-Gimeno, G., Matlin, O. S., Brennan, T. A., & Choudhry, N. K. (2013). Group-based trajectory models: A new approach to classifying and predicting long-term medication adherence. Medical Care, 51(9), 789–796. https://doi.org/10.1097/MLR.0b013e3182984c1f
  • Hirasen, K., Evans, D., Maskew, M., Sanne, I. M., Shearer, K., Govathson, C., Malete, G., Kluberg, S., & Fox, M. P. (2018). The right combination – treatment outcomes among HIV-positive patients initiating first-line fixed-dose antiretroviral therapy in a public sector HIV clinic in Johannesburg, South Africa. Clinical Epidemiology, 10, 17–29. https://doi.org/10.2147/CLEP.S145983
  • Hodder, S. L., Mounzer, K., Dejesus, E., Ebrahimi, R., Grimm, K., Esker, S., Ecker, J., Farajallah, A., Flaherty, J. F. (2010). Patient-reported outcomes in virologically suppressed, HIV-1-Infected subjects after switching to a simplified, single-tablet regimen of efavirenz, emtricitabine, and tenofovir DF. AIDS Patient Care and STDs, 24(2), 87–96. https://doi.org/10.1089/apc.2009.0259
  • The Joint United Nations Programme on HIV/AIDS. (2016). Aids by the numbers.
  • The Joint United Nations Programme on HIV/AIDS. (2017). Ending aids: Progress towards the 90-90-90 targets.
  • Jones, B. L., & Nagin, D. S. (2013). A note on a Stata plugin for estimating group-based trajectory models. Sociological Methods & Research, 42(4), 608–613. https://doi.org/10.1177/0049124113503141
  • Kalichman, S. C., Cherry, C., Amaral, C. M., Swetzes, C., Eaton, L., Macy, R., Grebler, T., & Kalichman, M. O. (2010). Adherence to antiretroviral therapy and HIV transmission risks: Implications for test-and-treat approaches to HIV prevention. AIDS Patient Care and STDs, 24(5), 271–277. https://doi.org/10.1089/apc.2009.0309
  • Librero, J., Sanfelix-Gimeno, G., Peiro, S., & Ahrens, I. (2016). Medication adherence patterns after hospitalization for coronary heart disease. A population-based study using electronic records and group-based trajectory models. PLoS One, 11(8). Article e0161381. https://doi.org/10.1371/journal.pone.0161381
  • Lima, V. D., Harrigan, R., Bangsberg, D. R., Hogg, R. S., Gross, R., Yip, B., & Montaner, J. S. (2009). The combined effect of modern highly active antiretroviral therapy regimens and adherence on mortality over time. JAIDS Journal of Acquired Immune Deficiency Syndromes, 50(5), 529–536. https://doi.org/10.1097/QAI.0b013e31819675e9
  • Liu, H., Miller, L. G., Hays, R. D., Golin, C. E., Wu, T., Wenger, N. S., & Kaplan, A. H. (2006). Repeated measures longitudinal analyses of HIV virologic response as a function of percent adherence, dose timing, genotypic sensitivity, and other factors. JAIDS Journal of Acquired Immune Deficiency Syndromes, 41(3), 315–322. https://doi.org/10.1097/01.qai.0000197071.77482.6e
  • Lo-Ciganic, W.-H., Donohue, J. M., Jones, B. L., Perera, S., Thorpe, J. M., Thorpe, C. T., Marcum, Z. A., & Gellad, W. F. (2016). Trajectories of diabetes medication adherence and hospitalization risk: A retrospective cohort study in a large state medicaid program. Journal of General Internal Medicine, 31(9), 1052–1060. https://doi.org/10.1007/s11606-016-3747-6
  • MacEwan, J. P., Forma, F. M., Shafrin, J., Hatch, A., Lakdawalla, D. N., & Lindenmayer, J. P. (2016). Patterns of adherence to oral atypical antipsychotics among patients diagnosed with schizophrenia. Journal of Managed Care & Specialty Pharmacy, 22(11), 1349–1361. https://doi.org/10.18553/jmcp.2016.22.11.1349
  • Mannheimer, S. B., Matts, J., Telzak, E., Chesney, M., Child, C., Wu, A. W., Friedland, G., & Terry Beirn Community Programs for Clinical Research on Aids. (2005). Quality of life in HIV-infected individuals receiving antiretroviral therapy is related to adherence. AIDS Care, 17(1), 10–22. https://doi.org/10.1080/09540120412331305098
  • Martin, D., Luz, P. M., Lake, J. E., Clark, J. L., Campos, D. P., Veloso, V. G., Moreira, R. I., Cardoso, S. W., Klausner, J. D., & Grinsztejn, B. (2017). Pharmacy refill data can be used to predict virologic failure for patients on antiretroviral therapy in Brazil. Journal of the International AIDS Society, 20(1). Article 21405. https://doi.org/10.7448/IAS.20.1.21405
  • Martin, S., Wolters, P. L., Calabrese, S. K., Toledo-Tamula, M. A., Wood, L. V., Roby, G., & Elliott-DeSorbo, D. K. (2007). The antiretroviral regimen complexity index. A novel method of quantifying regimen complexity. JAIDS Journal of Acquired Immune Deficiency Syndromes, 45(5), 535–544. https://doi.org/10.1097/QAI.0b013e31811ed1f1
  • Nachega, J. B., Parienti, J.-J., Uthman, O. A., Gross, R., Dowdy, D. W., Sax, P. E., Gallant, J. E., Mugavero, M. J., Mills, E. J., & Giordano, T. P. (2014). Lower pill burden and once-daily antiretroviral treatment regimens for HIV infection: A meta-analysis of randomized controlled trials. Clinical Infectious Diseases, 58(9), 1297–1307. https://doi.org/10.1093/cid/ciu046
  • Nagin, D. S., & Odgers, C. L. (2010). Group-based trajectory modeling in clinical research. Annual Review of Clinical Psychology, 6, 109–138. https://doi.org/10.1146/annurev.clinpsy.121208.131413
  • Raffi, F., Yazdanpanah, Y., Fagnani, F., Laurendeau, C., Lafuma, A., & Gourmelen, J. (2015). Persistence and adherence to single-tablet regimens in HIV treatment: A cohort study from the French national Healthcare Insurance database. Journal of Antimicrobial Chemotherapy, 70(7), 2121–2128. https://doi.org/10.1093/jac/dkv083
  • Schaecher, K. L. (2013). The importance of treatment adherence in HIV. The American Journal of Manag Care, 19(12 Suppl), s231–s237.
  • Scott Sutton, S., Magagnoli, J., & Hardin, J. W. (2016). Impact of pill burden on adherence, risk of hospitalization, and viral suppression in patients with HIV infection and AIDS receiving antiretroviral therapy. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 36(4), 385–401. https://doi.org/10.1002/phar.1728
  • Singh, N., Squier, C., Sivek, C., Wagener, M., Nguyen, M. H., & Yu, V. L. (1996). Determinants of compliance with antiretroviral therapy in patients with human immunodeficiency virus: Prospective assessment with implications for enhancing compliance. AIDS Care, 8(3), 261–270. https://doi.org/10.1080/09540129650125696
  • Stirratt, M. J., Curtis, J. R., Danila, M. I., Hansen, R., Miller, M. J., & Gakumo, C. A. (2018). Advancing the science and practice of medication adherence. Journal of General Internal Medicine, 33(2), 216–222. https://doi.org/10.1007/s11606-017-4198-4
  • Sungkanuparph, S., Anekthananon, T., Hiransuthikul, N., Bowonwatanuwong, C., Supparatpinyo, K., Mootsikapun, P., Chetchotisakd, P., Kiertiburanakul, S., Tansuphaswadikul, S., Buppanharun, W., Manosuthi, W., Techasathit, W., Ratanasuwan, W., Tantisiriwat, W., Suwanagool, S., Leechawengwongs, M., Ruxrungtham, K., & Thai AIDS Society. (2008). Guidelines for antiretroviral therapy in HIV-1 infected adults and adolescents: The recommendations of the Thai AIDS Society (TAS) 2008. Journal of the Medical Association of Thailand, 91(12), 1925–1935.
  • Vera, J., Aragao, F., Guimaraes, M., & Vaz Pinto, I. (2012). Benefits of ART simplification on adherence, clinical and economic outcomes. Journal of the International Aids Society, 15, 26–27. https://doi.org/10.7448/Ias.15.6.18064
  • Vrijens, B., De Geest, S., Hughes, D. A., Przemyslaw, K., Demonceau, J., Ruppar, T., Dobbels, F., Fargher, E., Morrison, V., Lewek, P., Matyjaszczyk, M., Mshelia, C., Clyne, W., Aronson, J. K., & Urquhart, J. (2012). A new taxonomy for describing and defining adherence to medications. British Journal of Clinical Pharmacology, 73(5), 691–705. https://doi.org/10.1111/j.1365-2125.2012.04167.x

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