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AIDS Care
Psychological and Socio-medical Aspects of AIDS/HIV
Volume 35, 2023 - Issue 1
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Research Article

Predictors of treatment interruption among patients on antiretroviral therapy in Akwa Ibom, Nigeria: outcomes after 12 months

, , , , , , , , & ORCID Icon show all
Pages 114-122 | Received 24 Feb 2021, Accepted 20 Jun 2022, Published online: 28 Jun 2022

References

  • Agaba, P. A., Meloni, S. T., Sule, H. M., Agbaji, O. O., Sagay, A. S., Okonkwo, P., Idoko, J. A., & Kanki, P. J. (2017). Treatment outcomes among older human immunodeficiency virus-infected adults in Nigeria. Open Forum Infectious Diseases, 4(2), ofx031. https://doi.org/10.1093/ofid/ofx031
  • Akilimali, P. Z., Musumari, P. M., Kashala-Abotnes, E., Kayembe, P. K., Lepira, F. B., Mutombo, P. B., Tylleskar, T., Ali, M. M., & Faragher, E. B. (2017). Disclosure of HIV status and its impact on the loss in the follow-up of HIV-infected patients on potent anti-retroviral therapy programs in a (post-) conflict setting: A retrospective cohort study from Goma, democratic Republic of Congo. PLOS ONE, 12(2), e0171407. https://doi.org/10.1371/journal.pone.0171407
  • Aliyu, A., Adelekan, B., Andrew, N., Ekong, E., Dapiap, S., Murtala-Ibrahim, F., Nta, I., Ndembi, N., Mensah, C., & Dakum, P. (2019). Predictors of loss to follow-up in art experienced patients in Nigeria: A 13-year review (2004–2017). AIDS Research and Therapy, 16(1), 30. https://doi.org/10.1186/s12981-019-0241-3
  • Alvarez-Uria, G., Naik, P. K., Pakam, R., & Midde, M. (2013). Factors associated with attrition, mortality, and loss to follow up after antiretroviral therapy initiation: Data from an HIV cohort study in India. Global Health Action, 6(1), 21682. https://doi.org/10.3402/gha.v6i0.21682
  • Amankwaa, I., Boateng, D., Quansah, D. Y., Akuoko, C. P., & Evans, C. (2018). Effectiveness of short message services and voice call interventions for antiretroviral therapy adherence and other outcomes: A systematic review and meta-analysis. PLoS One, 13(9), e0204091. https://doi.org/10.1371/journal.pone.0204091. PMID: 30240417; PMCID: PMC6150661.
  • Asiimwe, S. B., Kanyesigye, M., Bwana, B., Okello, S., & Muyindike, W. (2015). Predictors of dropout from care among HIV-infected patients initiating antiretroviral therapy at a public sector HIV treatment clinic in sub-Saharan Africa. BMC Infectious Diseases, 16(1), 43. https://doi.org/10.1186/s12879-016-1392-7
  • Assemie, M. A., Muchie, K. F., & Ayele, T. A. (2018). Incidence and predictors of loss to follow up among HIV-infected adults at Pawi general hospital, northwest Ethiopia: Competing risk regression model. BMC Research Notes, 11(1), 1–6. https://doi.org/10.1186/s13104-018-3407-5
  • Ayele, W., Mulugeta, A., Desta, A., & Rabito, F. A. (2015). Treatment outcomes and their determinants in HIV patients on anti-retroviral treatment program in selected health facilities of Kembata and Hadiya zones, southern nations, nationalities and peoples region, Ethiopia. BMC Public Health, 15(1), 826. https://doi.org/10.1186/s12889-015-2176-5
  • Babatunde, O., Ojo, O. J., Atoyebi, O. A., Ekpo, D. S., Ogundana, A. O., Olaniyan, T. O., & Owoade, J. A. (2015 Oct 14). Seven-year review of retention in HIV care and treatment in federal medical centre Ido-ekiti. Pan African Medical Journal, 22(139), 139. https://doi.org/10.11604/pamj.2015.22.139.4981
  • Balogun, M., Meloni, S. T., Igwilo, U. U., Roberts, A., Okafor, I., Sekoni, A., Ogunsola, F., Kanki, P. J., & Akanmu, S. (2019). Status of HIV-infected patients classified as lost to follow up from a large antiretroviral program in southwest Nigeria. PloS One, 14(7), e0219903. https://doi.org/10.1371/journal.pone.0219903
  • Bekolo, C. E., Webster, J., Bateganya, M., Sume, G. E., & Kollo, B. (2013). Trends in mortality and loss to follow-up in HIV care at the Nkongsamba regional hospital, Cameroon. BMC Research Notes, 6(1), 1–16. https://doi.org/10.1186/1756-0500-6-512
  • Berheto, T. M., Haile, D. B., & Mohammed, S. (2014). Predictors of loss to follow-up in patients living with HIV/AIDS after initiation of antiretroviral therapy. North American Journal of Medical Sciences, 6(9), 453–459. https://doi.org/10.4103/1947-2714.141636
  • Bilinski, A., Birru, E., Peckarsky, M., Herce, M., Kalanga, N., et al. (2017). Distance to care, enrollment and loss to follow-up of HIV patients during decentralization of antiretroviral therapy in Neno district, Malawi: A retrospective cohort study. PLoS One, 12(10), e0185699.
  • Brinkhof, M. W., Pujades-Rodriguez, M., & Egger, M. (2009). Mortality of patients lost to follow-up in antiretroviral treatment programmes in resource-limited settings: Systematic review and meta-analysis. PLoS One, 4(6), e5790. https://doi.org/10.1371/journal.pone.0005790
  • Charurat, M., Oyegunle, M., Benjamin, R., Habib, A., Eze, E., Ele, P., Ibanga, I., Ajayi, S., Eng, M., Mondal, P., Gebi, U., Iwu, E., Etiebet, M-A., Abimiku, A., Dakum, P., Farley, J., Blattner, W., & Myer, L. (2010). Patient retention, and adherence to antiretrovirals in a large antiretroviral therapy program in Nigeria: A longitudinal analysis for risk factors. PLoS One, 5(5), e10584. https://doi.org/10.1371/journal.pone.0010584
  • Dalhatu, I., Onotu, D., Odafe, S., Abiri, O., Debem, H., Agolory, S., Shiraishi, R.W., Auld, A. F., Swaminathan, M., Dokubo, K., Ngige, E., Asadu, C., Abatta, E., Ellerbrock, T. V., & Anglewicz, P. (2016). Outcomes of Nigeria’s HIV/AIDS treatment program for patients initiated on antiretroviral treatment between 2004–2012. PLoS One, 11(11), e0165528. https://doi.org/10.1371/journal.pone.0165528
  • Data.FI. (2020). Improving patient retention on antiretroviral treatment through high frequency reporting in Akwa Ibom state. Data.FI, Palladium.
  • Eguzo, K. N., Lawal, A. K., Eseigbe, C. E., & Umezurike, C. (2014, August 6). Determinants of mortality among adult HIV-infected patients on antiretroviral therapy in a rural hospital in southeastern Nigeria: A 5-year cohort study. AIDS Research and Treatment, 2014, Article ID 867827. https://doi.org/10.1155/2014/867827
  • Emdin, C., Chong, N. J., & Millson, P. E. (2013). Non-physician clinician provided HIV treatment results in equivalent outcomes as physician-provided care: A meta-analysis. Journal of the International AIDS Society, 16, 18445.
  • Eshun-Wilson, I., Rohwer, A., Hendricks, L., Oliver, S., Garner, P., & Isaakidis, P. (2019). Being HIV positive and staying on antiretroviral therapy in Africa: A qualitative systematic review and theoretical model. PLoS One, 14(1), e0210408–30. https://doi.org/10.1371/journal.pone.0210408
  • Faturiyele, I. O., Appolinare, T., Ngorima-Mabhena, N., Fatti G., Tshabalala I., Tukei V. J., & Pisa P. T. (2018). Outcomes of community-based differentiated models of multi-month dispensing of antiretroviral medication among stable HIV-infected patients in Lesotho: A cluster randomised non-inferiority trial protocol. BMC Public Health, 18(1), 1069. https://doi.org/10.1186/s12889-018-5961-0
  • Federal Ministry of Health. (2014). Task-shifting and task sharing policy for essential health care services in Nigeria.
  • Federal Ministry of Health. (2016). National Guidelines for HIV prevention treatment and care. National AIDS and STIs Control programme. https://naca.gov.ng/wp-content/uploads/2019/03/NATIONAL-HIV-AND-AIDS-STRATEGIC-FRAMEWORK-1.pdf
  • Folasire, O. F., Irabor, A. E., & Folasire, A. M. (2012). Quality of life of people living with HIV and AIDS attending the antiretroviral clinic, University college hospital, Nigeria. African Journal of Primary Health Care & Family Medicine, 4(1), 294. https://doi.org/10.4102/phcfm.v4i1.294
  • Fox, M. P., & Rosen, S. (2010). Patient retention in antiretroviral therapy programs up to three years on treatment in sub-Saharan Africa, 2007–2009: A systematic review. Tropical Medicine & International Health, 15(Suppl 1), 1–15. https://doi.org/10.1111/j.1365-3156.2010.02508.x
  • Harries, A. D., Zachariah, R., Lawn, S. D., & Rosen, S. (2010). Strategies to improve patient retention on antiretroviral therapy in sub-Saharan Africa. Tropical Medicine & International Health, 15(Suppl 1), 70–75. https://doi.org/10.1111/j.1365-3156.2010.02506.x
  • Hønge, B. L., Jespersen, S., Nordentoft, P. B., Medina, C., da Silva, D., da Silva, Z. J., Østergaard, L., Laursen, A. L., & Wejse, C. (2013). Loss to follow-up occurs at all stages in the diagnostic and follow-up period among HIV-infected patients in Guinea-Bissau: A 7-year retrospective cohort study. BMJ Open, 3(10), e003499–10. https://doi.org/10.1136/bmjopen-2013-003499
  • Kolawole, G. A., Gilbert, H. N., Dadem, N. Y., Genberg, B. L., Agaba, P. A., et al. (2017). Patient experiences of decentralized HIV treatment and care in plateau state, North central Nigeria: A qualitative study. Aids Research and Treatment, 2017, 2838059. https://doi.org/10.1155/2017/2838059
  • Mberi, M. N., Kuonza, L. R., Dube, N. M., Nattey, C., Manda, S., & Summers, R. (2015). Determinants of loss to follow-up in patients on antiretroviral treatment, South Africa, 2004-2012: A cohort study. BMC Health Services Research, 15(1), 259. https://doi.org/10.1186/s12913-015-0912-2
  • Mekonnen, N., Abdulkadir, M., Shumetie, E., Baraki, A. G., & Yenit, M. K. (2019). Incidence and predictors of loss to follow-up among HIV infected adults after initiation of first line anti-retroviral therapy at University of Gondar comprehensive specialized hospital northwest Ethiopia, 2018: Retrospective follow up study. BMC Research Notes, 12(1), 111. https://doi.org/10.1186/s13104-019-4154-y
  • Meloni, S. T., Chang, C., Chaplin, B., Rawizza, H., Jolayemi, O., Banigbe, B., Okonkwo, P., & Kanki, P. (2014). Time-Dependent predictors of loss to follow-Up in a large HIV treatment cohort in Nigeria. Open Forum Infectious Diseases, 1(2), ofu055. https://doi.org/10.1093/ofid/ofu055
  • Monroe, A., Nakigozi, G., Ddaaki, W., Bazaale, J. M., Gray, R. H., Wawer, M. J., Reynolds, S. J., Kennedy, C. E., & Chang, L. W. (2017). Qualitative insights into implementation, processes, and outcomes of a randomized trial on peer support and HIV care engagement in Rakai, Uganda. BMC Infectious Diseases, 17(1), 54. https://doi.org/10.1186/s12879-016-2156-0
  • Nabitaka, V. M., Nawaggi, P., Campbell, J., Conroy, J., Harwell, J., Magambo, K., Middlecote, C., Caldwell, B., Katureebe, C., Namuwenge, N., Atugonza, R., Musoke, A., Musinguzi, J., & Torpey, K. (2020). High acceptability, and viral suppression of patients on dolutegravir-based first-line regimens in pilot sites in Uganda: A mixed-methods prospective cohort study. PLoS One, 15(5), e0232419. https://doi.org/10.1371/journal.pone.0232419
  • National Agency for the Control of AIDS (NACA). (2019). Nigeria HIV/AIDS indicator and impact survey (NAIIS) south zone summary sheet. NACA. https://naca.gov.ng/wp-content/uploads/2019/03/NAIIS-SOUTH-SOUTH-ZONE-FACTSHEET_V0.9_030719-edits.pdf
  • Nigeria Government. Nigeria country operational plan (COP). (2020). 2020 strategic direction summary. Abuja (Nigeria): Nigeria Government; 2020. https://www.state.gov/wp-content/uploads/2020/07/COP-2020-Nigeria-SDS-Final-.pdf
  • Odafe, S., Idoko, O., Badru, T., Aiyenigba, B., Suzuki, C., Khamofu, H., Onyekwena, O., Okechukwu, E., Torpey, K., & Chabikuli, O. N. (2012). Patients’ demographic and clinical characteristics and level of care associated with lost to follow-up and mortality in adult patients on first-line ART in Nigerian hospitals. Journal of the International AIDS Society, 15(2), 17424. https://doi.org/10.7448/IAS.15.2.17424
  • Oguntibeju, O. O. (2012). Quality of life of people living with HIV and AIDS and antiretroviral therapy. HIV/AIDS - Research and Palliative Care, 4(4), 117–124. https://doi.org/10.2147/HIV.S32321
  • Onoka, C. A., Uzochukwu, B. S., Onwujekwe, O. E., Chukwuka, C., Ilozumba, J., Onyedum, C., Nwobi, E. A., & Onwasigwe, C. (2012). Retention and loss to follow-up in antiretroviral treatment programmes in southeast Nigeria. Pathogens and Global Health, 106(1), 46–54. https://doi.org/10.1179/2047773211Y.0000000018
  • Penn, A. W., Azman, H., Horvath, H., Taylor, K. D., Hickey, M. D., Rajan, J., Negussie, E. K., Doherty, M., & Rutherford, G. W. (2018, December 14). Supportive interventions to improve retention on ART in people with HIV in low- and middle-income countries: A systematic review. PLoS One, 13(12), e0208814. https://doi.org/10.1371/journal.pone.0208814
  • Pepfar Solutions Platform. (2018). Improving patient antiretroviral therapy retention through Community Adherence Groups in Zambia. https://www.pepfarsolutions.org/solutions/2018/1/16/decongesting-art-clinics-in-zambia-and-improving-patients-retention-through-community-adherence-groups-mrbtk
  • Rubaihayo, J., Tumwesigye, N. M., & Konde-Lule, J. (2015). Trends in prevalence of selected opportunistic infections associated with HIV/AIDS in Uganda. BMC Infectious Diseases, 15(1), 187. https://doi.org/10.1186/s12879-015-0927-7
  • Seifu, W., Ali, W., & Meresa, B. (2018). Predictors of loss to follow up among adult clients attending antiretroviral treatment at Karamara general hospital, Jigjiga town, Eastern Ethiopia, 2015: A retrospective cohort study. BMC Infectious Diseases, 18(1), 1–8. https://doi.org/10.1186/s12879-017-2892-9
  • Shah, R., Watson, J., & Free, C. (2019). A systematic review and meta-analysis in the effectiveness of mobile phone interventions used to improve adherence to antiretroviral therapy in HIV infection. BMC Public Health, 19(1), 915. https://doi.org/10.1186/s12889-019-6899-6. PMID: 31288772; PMCID: PMC6617638.
  • Stricker, S. M., Fox, K. A., Baggaley, R., Negussie, E., de Pee, S., Grede, N., & Bloem, M. W. (2014). Retention in care and adherence to ART are critical elements of HIV care interventions. AIDS and Behavior, 18(S5), 465–475. https://doi.org/10.1007/s10461-013-0598-6
  • Tadesse, K., & Haile, F. (2014). Predictors of loss to follow up of patients enrolled on antiretroviral therapy: A retrospective cohort study. Journal of AIDS & Clinical Research, 5(5), 393. https://doi.org/10.4172/2155-6113.1000393
  • Tiruneh, Y. M., Galárraga, O., Genberg, B., Wilson, I. B., & Thorne, C. (2016). Retention in care among HIV-infected adults in Ethiopia, 2005–2011: A mixed-methods study. PLoS One, 11(6), e0156619–11. https://doi.org/10.1371/journal.pone.0156619
  • Webb, S., & Hartland, J. (2018). A retrospective notes-based review of patients lost to follow-up from anti-retroviral therapy at Mulanje mission hospital, Malawi. Malawi Medical Journal, 30(2), 73–78. https://doi.org/10.4314/mmj.v30i2.4