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Original

Brain imaging research: Does the science serve clinical practice?

, M.D., Ph.D., &
Pages 541-558 | Published online: 11 Jul 2009

References

  • Abi-Dargham A, Rodenhiser J, Printz D, Zea-Ponce Y, Gil R, Kegeles LS, et al. Increased baseline occupancy of D2 receptors by dopamine in schizophrenia. Proceedings of the National Academy of Sciences of the United States of America 2000; 97: 8104–8109
  • Abi-Dargham A, Mawlawi O, Lombardo I, Gil R, Martinez D, Huang Y, et al. Prefrontal dopamine D1 receptors and working memory in schizophrenia. Journal of Neuroscience 2002; 22: 3708–3719
  • Alexander M, Rothman RB, Baumann MH, Brašić JR, Wong DF, Endres C. A dose-response PET study of the noradrenergic and dopaminergic effects of amphetamine-like stimulants in baboon. Journal of Nuclear Medicine 2004; 45, (5 supplement), 256 [abstract]
  • Alexander M, Rothman RB, Baumann MH, Endres CJ, Brašić JR, Wong DF. Noradrenergic and dopaminergic effects of (+)-amphetamine-like stimulants in the baboon. Papio anubis. Synapse 2005; 56: 94–99
  • Alexander M, Rothman RB, Endres C, Rauseo P, Brašić JR, Maini A, et al. A dose-response PET study of the noradrenergic and dopaminergic effects of amphetamine-like stimulants in baboons. Journal of Nuclear Medicine 2003; 44, (5 supplement), 221 [abstract]
  • American Psychiatric Association. Diagnostic and statistical manual of mental disorders (4th ed., text revision, (DSM-IV-TR™)). American Psychiatric Association, Washington 2000
  • Berding G, Müller-Vahl K, Schneider U, Gielow P, Fitschen J, Stuhrmann M, et al. [123I]AM281 single-photon emission computed tomography imaging of central cannabinoid CB1 receptors before and after Δ9-tetrahydrocannabinol therapy and whole-body scanning for assessment of radiation dose in Tourette patients. Biological Psychiatry 2004; 55: 904–915
  • Bibat GM, Brašić JR, Dogan AS, Kuwabara H, Maini A, Maris MA, et al. Determination of presynaptic acetycholine terminal densities and its clinical correlation in Rett's syndrome. Annals of Neurology 2003; 54, (Issue Supplement 7), S118 [abstract]
  • Bibat GM, Brašić JR, Dogan AS, Kuwabara H, Maini A, Maris MA, et al. Reduced acetylcholine vesicular transport in adults with Rett Syndrome: Clinical correlation and therapeutic implications. Neurology 2004; 62, (7 suppl), A28 [abstract]
  • Brašić JR. The emergency evaluation of organic brain syndrome. Proceedings of the Twenty-Sixth Annual Conference of Air Force Behavioral Scientists, RA Levy. United States Air Force School of Aerospace Medicine, Aerospace Medical Division (AFSC), Texas 1979; 148–158, Brooke Air Force Base
  • Brašić JR. Hallucinations. Perceptual and Motor Skills 1998; 86: 851–877
  • Brašić JR. Differentiating myoclonus from tics. Psychological Reports 2000; 86(1)155–156
  • Brašić JR. Clinical assessment of tics. Psychological Reports 2001; 89: 48–50
  • Brašić JR. Treatment of movement disorders in autism spectrum disorders. Autism Spectrum Disorders, E. Hollander. Marcel Dekker, Inc, New York 2003; 273–346
  • Brašić JR, Dogan AS, Kuwabara H, Maini A, Bibat G, Naidu S, et al. Deficient presynaptic acetylcholine terminal densities in the brain of adults with Rett syndrome who demonstrate impaired performance of the activities of daily living. Poster Abstracts, 4th Annual Rett Syndrome Symposium, June 2325, 2003, Inn at the Colonnade, Baltimore, Maryland. Rett Syndrome Research Foundation (RSRF), Cincinnati 2003; 29
  • Brašić JR, Musachio JL, Zhou Y, Cascella N, Nestadt G, Osman M, et al. Neuropsychiatric assessment of [123I]iodo-3-(2 azetidinylmethoxy)pyridine. Movement Disorders 2001a; 16(supplement 1)S54, abstract
  • Brašić JR, Osman M, Gay O, Arkles JS, Kalaff A, Belle AS, et al. Characteristics of volunteers for neuroimaging studies of Tourette's disorder. Movement Disorders 2001b; 16(supplement 1)S47, abstract
  • Brašić JR, Wong D, Eroglu A. PET scanning in autism spectrum disorders. eMedicine Journal 2006; 7(2), Accessed on http://www.emedicine.com/neuro/topic440.htm
  • Brašić JR, Zhou Y, Musachio J, Hilton J, Fan H, Crabb A, et al. Neuropsychiatric assessment of (S)-5-[123I]iodo-3-(2-azetidinylmethoxy)pyridine (5IA). 5th Annual Rett Syndrome Symposium, June 28-30, 2004, Inn at the Colonnade, Baltimore, Maryland. Rett Syndrome Research Foundation (RSRF), Cincinnati 2004; 44, www.rsrf.org [abstract]
  • Breier A, Su T-P, Saunders R, Carson RE, Kolachana BS, de Bartolomeis A, et al. Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: Evidence from a novel positron emission tomography method. Proceedings of the National Academy of Sciences of the United States of America 1997; 94: 2569–2574
  • Brooks DJ. Positron emission tomography imaging of transplant function. NeuroRx®: The Journal of the American Society for Experimental NeuroTherapeutics 2004; 1: 482–491
  • Carlsson A. The current status of the dopamine hypothesis of schizophrenia. Neuropsychopharmacology 1988; 1(3)179–186
  • Dewey SL, Morgan AE, Ashby Jr. CR, Horan B, Kushner SA, Logan J, et al. A novel strategy for the treatment of cocaine addiction. Synapse 1998; 30: 119–129
  • Dogan AS, Brašić JR, Kuwabara H, Maini A, Bibat G, Naidu S, et al. Deficiencies of striatal vesicular acetylcholine transporter binding and activities of daily living in Rett disorder. Journal of Nuclear Medicine 2003; 44(5 supplement)15, abstract
  • Dogan AS, Catafau AM, Zhou Y, Crabb AH, Yanai K, Offord S, et al. In vivo histamine H-1 receptor mapping in normal human brain using 11C-doxepin PET. European Journal of Nuclear Medicine and Molecular Imaging 2001a; 28(8)973, abstract
  • Dogan AS, Catafau AM, Zhou Y, Yanai K, Ravert H, Brašić J, et al. In vivo cerebral histamine receptor occupancy of three antihistamine drugs: A 11C-doxepin PET study. European Journal of Nuclear Medicine and Molecular Imaging 2001b; 28(8)974, abstract
  • Dogan AS, Catafau AM, Zhou Y, Yanai K, Ravert H, Brašić J, et al. In vivo cerebral histamine receptor occupancy of three antihistamine drugs: A 11C-doxepin PET study. The Journal of Nuclear Medicine 2001c; 42: 143–144, abstract
  • Eckert T, Eidelberg D. Neuroimaging and therapeutics in movement disorders. NeuroRx®: The Journal of the American Society for Experimental NeuroTherapeutics 2005; 2: 361–371
  • Endres C, Dogan S, Brašić J, Zhou Y, Hilton J, London ED, et al. Comparison between bolus and infusion [11C]raclopride delivery for the quantification of dopamine release associated with craving for cocaine. Journal of Cerebral Blood Flow and Metabolism 2001; 21(suppl 1)S540, abstract
  • Endres CJ, Dogan AS, Brašić JR, Zhou Y, Hilton J, London ED, . Comparison between bolus and infusion[11C]raclopride delivery for the quantification of dopamine release. Brain imaging using PET, M. Senda, Y. Kimura, P. Herscovitch, et al. Academic Press, Amsterdam 2002; 71–75
  • Erhart SM, Young AS, Marder SR, Mintz J. Clinical utility of magnetic resonance imaging radiographs for suspected organic syndromes in adult psychiatry. Journal of Clinical Psychiatry 2005; 66: 968–973
  • Farde L, Nordström AL, Wiesel FA, Pauli S, Halldin C, Sedvall G. Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects. Archives of General Psychiatry 1992; 49: 538–544
  • Gründer G, Carlsson A, Wong DF. Mechanism of new antipsychotic medications: Occupancy is not just antagonism. Archives of General Psychiatry 2003; 60: 974–977
  • Gründer G, Landvogt C, Vernaleken I, Buchholz H-G, Ondracek J, Siessmeier T, et al. The striatal and extrastriatal D2/D3 receptor binding profile of clozapine in patients with schizophrenia. Neuropsychopharmacology 2006; 31: 1027–1035
  • Gründer G, Yokoi F, Offord SJ, Ravert HT, Dannals RF, Salzmann JK, et al. Time course of 5-HT2A receptor occupancy in the human brain after a single oral dose of the putative antipsychotic drug MDL 100,907 measured by positron emission tomography. Neuropsychopharmacology 1997; 17: 175–185
  • Gründer G, Yokoi F, Offord SJ, Ravert HT, Dannals RF, Salzmann JK, et al. Time course of 5-HT2A receptor occupancy in the human brain after a single oral dose of the putative antipsychotic drug MDL 100,907 measured by positron emission tomography. Neuropsychopharmacology 1998; 19: 161, erratum
  • Harris JC, Jinnah HA, Schretlen D, O’Neill P, Lilystrom JM, Yokoi F, et al. A female case of Lesch-Nyhan syndrome (LNS) with a normal twin: Clinical, neuropsychological and radiological findings. Abstracts, Society for Neuroscience, 30th Annual Meeting. Louisiana, New Orleans November 4–9, 2000; 1327, 26 (Part 1). Abstract 495.9 [abstract]
  • Jucaite A, Fernell E, Halldin C, Forssberg H, Farde L. Reduced midbrain dopamine transporter binding in male adolescents with attention-deficit/hyperactivity disorder: Association between striatal dopamine markers and motor hyperactivity. Biological Psychiatry 2005; 57: 229–238
  • Kapur S, Zipursky RB, Remington G. Clinical and theoretical implications of 5-HT2 and D2 receptor occupancy of clozapine, risperidone, and olanzapine in schizophrenia. American Journal of Psychiatry 1999; 156: 286–293
  • Kéri S. The cognitive neuroscience of category learning. Brain Research, Brain Research Reviews 2003; 43: 85–109
  • Klunk WE, Engler H, Nordberg A, Wang Y, Blomqvist G, Holt DP, et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Annals of Neurology 2004; 55: 306–319
  • Kuwabara H, Brašić JR, Ye W, Schneider J, Wong DF. [11C]methylphenidate PET demonstrates relative preservation of dopamine transporters in the ventral striatum in Parkinson's disease. Journal of Nuclear Medicine 2005a; 48, (5 abstract book supplement), 127 [abstract]
  • Kuwabara H, Kumar A, Brašić J, Nandi A, Wong DF. Estimation of receptor occupancy and synaptic dopamine after amphetamine challenge: A competition model approach. Journal of Cerebral Blood Flow & Metabolism 2005b; 25, S613–S613 [abstract]
  • Lafargue T, Brašić J. Neurodevelopmental hypothesis of schizophrenia: A central sensory disturbance. Medical Hypotheses 2000; 55: 314–318
  • Laihinen A, Halsband U. PET imaging of the basal ganglia. Journal of Physiology–Paris 2006; 99: 406–413
  • Laruelle M. Imaging dopamine transmission in schizophrenia. A review and meta-analysis. Quarterly Journal of Nuclear Medicine 1998; 42: 211–221
  • Laruelle M, Abi-Dargham A, van Dyck CH, Gil R, D'Souza CD, Erdos J, et al. Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects. Proceedings of the National Academy of Sciences of the United States of America 1996; 93: 9235–9240
  • Maini A, Brašić JR, Alexander M, Kuwabara H, Zhou Y, Gries JM, et al. Estimation of human D3 receptor occupancy with 11C raclopride PET. Journal of Nuclear Medicine 2003a; 44(5 supplement)223, abstract
  • Maini A, Wong DF, Oswald LM, Lee JS, Kuwabara H, Zhou Y, et al. Brain dopamine release correlates with neuroendocrine stress measures and subjective response: Implications for alcoholism. Abstracts of the 65th Annual Scientific Meeting of the College on Problems of Drug Dependence (CPDD). College on Problems of Drug Dependence (CPDD) [abstract], Bal Harbour, Florida 2003b; 104
  • Martinez D, Slifstein M, Broft A, Mawlawi O, Hwang D-R, Huang Y, et al. Imaging human mesolimbic dopamine transmission with positron emission tomography. Part II: Amphetamine-induced dopamine release in the functional subdivisions of the striatum. Journal of Cerebral Blood Flow and Metabolism 2003; 23: 285–300
  • Mintzer MZ, Kuwabara H, Alexander M, Brašić JR, Ye W, Ernst M, et al. Dose effects of triazolam on brain activity during episodic memory encoding: A PET study. Psychopharmacology 2006; 188: 445–461
  • Munro CA, McCaul ME, Oswald LM, Wong DF, Zhou Y, Brašić J, et al. Striatal dopamine release and family history of alcoholism. Alcoholism: Clinical and Experimental Research 2006a; 30: 1143–1151
  • Munro CA, McCaul ME, Wong DF, Oswald LM, Zhou Y, Brašić J, et al. Sex differences in striatal dopamine release in healthy adults. Biological Psychiatry 2006b; 59: 966–974
  • Musachio JL, Brašić JR, Scheffel UA, Rauseo PA, Fan H, Osman M, et al. Radiosynthesis, in vitro/in vivo pharmacologic characterization, and initial human SPECT imaging studies with [I-123] 5-iodo-A-85380: A high affinity nicotinic acetylcholine receptor (nAChR) radioprobe. American Chemical Society Meeting. Abstracts of papers. American Chemical Society, Washington 2001, District of Columbia, April 1, 2001, 221(Part 2), 183-NUCL [abstract]
  • Naidu S, Wong DF, Sanchez-Roa P, Villemagne V, Yaster M, Dannals RF, et al. Rett syndrome: PET metabolic-clinical correlates. Annals of Neurology 1988; 24, 305 [abstract
  • Oswald LM, Wong DF, McCaul M, Zhou Y, Kuwabara H, Choi L, et al. Relationships among ventral striatal dopamine release, cortisol secretion, and subjective responses to amphetamine. Neuropsychopharmacology 2005; 30: 821–832
  • Oswald LM, Wong DF, McCaul ME, Maini A, Lee JS, Kuwabara H, et al. Subjective and cortisol responses to IV amphetamine correlate with ventral striatal dopamine release. Alcoholism: Clinical and Experimental Research 2003; 27, (Supplement.), 21A [abstract]
  • Oswald LM, Wong DF, Zhou Y, Kumar A, Brašić JR, Alexander M. Impulsivity and chronic stress are associated with amphetamine-induced striatal dopamine release. Neuroimage 2007; 36: 153–166
  • Segawa M. Neurophysiology of Tourette's syndrome: Pathophysiological considerations. Brain & Development 2003; 25(supplement 1)S62–S69
  • Singer HS, Szymanski S, Giuliano J, Yokoi F, Dogan AS, Brašić JR, et al. Elevated intrasynaptic dopamine release in Tourette's syndrome measured by PET. American Journal of Psychiatry 2002; 159: 1329–1336
  • Tai YF, Pavese N, Gerhard A, Tabrizi SJ, Barker RA, Brooks DJ, et al. Imaging microglial activation in Huntington's disease. Brain Research Bulletin 2007; 72: 148–151
  • Tune LE, Wong DF, Pearlson G, Strauss M, Young T, Shaya EK, et al. Dopamine D2 receptor density estimates in schizophrenia: A positron emission tomography study with 11C-N-methylspiperone. Psychiatry Research 1993; 49: 219–237
  • Villemagne PM, Naidu S, Villemagne VL, Yaster M, Wagner Jr., H. N., Harris JC, et al. Brain glucose metabolism in Rett syndrome. Pediatric Neurology 2002; 27: 117–122
  • Volkow ND, Wang GJ, Newcorn J, Fowler JS, Telang F, Solanto MV, et al. Brain dopamine transporter levels in treatment and drug naïve adults with ADHD. Neuroimage 2007; 34(3)1182–1190
  • Volkow ND, Wang G-J, Fischman MW, Foltin RW, Fowler JS, Abumrad NN, et al. Relationship between subjective effects of cocaine and dopamine transporter occupancy. Nature 1997a; 386: 827–830, letter
  • Volkow ND, Wang G-J, Fowler JS, Logan J, Gatley SJ, Hitzemann R, et al. Decreased striatal dopaminergic responsiveness in detoxified cocaine-dependent subjects. Nature 1997b; 386: 830–833, letter
  • Wolkin A, Barouche F, Wolf AP, Rotrosen J, Fowler JS, Shiue CY, et al. Dopamine blockade and clinical response: Evidence for two biological subgroups of schizophrenia. American Journal of Psychiatry 1989; 146(7)905–908
  • Wong DF, Brašić JR. In vivo imaging of neurotransmitter systems in neuropsychiatry. Clinical Neuroscience Research 2001; 1: 35–45
  • Wong DF, Brašić JR. Progress in the neuropsychiatry of schizophrenia. Psychiatric Times 2005; 22(3)57, 58, 60
  • Wong DF, Brašić JR, Kuwabara H, Zhou Y, Schretlen D, Kumar A, et al. Abnormalities of dopamine and serotonin neuroreceptors documented with PET in Tourette syndrome. Journal of Nuclear Medicine 2005a; 48, (5 abstract book supplement), 182 [abstract]
  • Wong DF, Brašić JR, Zhou Y, Gay O, Crabb AH, Kuwabara H, et al. Human imaging of α4β2 nicotinic acetyocholine receptors in vivo using 123I5-iodo-A-85380. The Journal of Nuclear Medicine 2001a; 42, (5 supplement), 142 [abstract]
  • Wong DF, Endres C, Brašić J, Gay O, Ernst M, Schretlen D, et al. Changes in intrasynaptic dopamine induced by cocaine-related cues. Drug and alcohol dependence 2001b; 63, (supplement 1), S172 [abstract]
  • Wong DF, Harris JC, Naidu S, Yokoi F, Marenco S, Dannals DF, et al. Dopamine transporters are markedly reduced in Lesch-Nyhan disease in vivo. Proceedings of the National Academy of Sciences of the United States of America 1996a; 93: 5539–5543
  • Wong DF, Kuwabara H, Mozley DP, Dannals RF, Kumar A, Ye W, et al. Characterization of dose dependent norepinephrine transporter blockade by atomoxetine in human brain using 11C MeNER PET. Journal of Cerebral Blood Flow & Metabolism 2005b; 25: S599–S599, abstract
  • Wong DF, Kuwabara H, Schretlen DJ, Bonson KR, Zhou Y, Nandi A, et al. Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. Neuropsychopharmacology 2006; 31: 2716–2727
  • Wong DF, Kuwabara H, Schretlen DJ, Bonson KR, Zhou Y, Nandi A, et al. Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving. Neuropsychopharmacology 2007; 32: 256, erratum
  • Wong DF, Lee JS, Maini A, Zhou Y, Kuwabara H, Endres C, et al. Cue induced cocaine craving and dopamine release: methodology and correlates. Journal of Nuclear Medicine 2003a; 44(5 supplement), abstract
  • Wong DF, Lee JS, Zhou Y, Brašić J, Maini A, Kuwabara H, et al. Intrasynaptic dopamine release and cocaine craving induced by video/audio cues. Abstracts of the 65th Annual Scientific Meeting of the College on Problems of Drug Dependence (CPDD). College on Problems of Drug Dependence (CPDD) [abstract], Bal Harbour, Florida 2003b; 188
  • Wong DF, Jr., Maini A, Alexander M, Zhou Y, Brašić J, Scheffel U, et al. Imaging nicotinic receptors in the development of allosteric potentiating ligands for cognitive enhancement in Alzheimer's dementia. Journal of Nuclear Medicine 2002a; 43(5 Supplement)109–110, abstract
  • Wong DF, Maini A, Rousset OG, Brašić JR. Positron emission tomography—a tool for identifying the effects of alcohol dependence on the brain. Alcohol Research & Health 2003c; 27(2)161–173, http://pubs.niaaa.nih.gov/publications/arh27-2/161-173.pdf
  • Wong DF, Naidu S, Yokoi F, Grunder G, Szymanski S, Dannals RF, et al. In vivo imaging of pre- and postsynaptic dopamine receptors in Rett Syndrome. Society for Neuroscience 1996b; 22(1)23, abstract
  • Wong DF, Pearlson GD, Tune LE, Young LT, Meltzer CC, Dannals RF, et al. Quantification of neuroreceptors in the living human brain: IV Effect of aging and elevations of D2-like receptors in schizophrenia and bipolar illness. Journal of Cerebral Blood Flow & MetabMetabolism 1997; 17: 331–342
  • Wong DF, Pomper MG. Predicting the success of a radiopharmaceutical for in vivo imaging of central nervous system neuroreceptor systems. Molecular Imaging and Biology 2003; 5: 350–362
  • Wong DF, Potter WZ, Brašić JR. Proof of concept: Functional models for drug development in humans. Neuropsychopharmacology: The Fifth Generation of Progress, K. L. Davis, D. Charney, J. T. Coyle, C. Nemeroff. The American College of Neuropsychopharmacology and Lippincott Williams & Wilkins, Baltimore 2002b; 457–473
  • Wong DF, Ricaurte G, Grunder G, Rothman R, Naidu S, Singer H, . Dopamine transporter changes in neuropsychiatric disorders, . I. D. Goldstein, G. Eisenhofer, R. McCarty, et al. Academic Press, San Diego 1998
  • Wong DF, Scheffel U, Fan H, Brašić J, Maini A, Zukin S, et al. Imaging the mechanism of action in the biodistribution of galantamine and other potential allosteric potentiating ligands for dementia treatment. Society for Neuroscience [abstract], 19 Washington, DC 2002c, Program No. 506.
  • Wong DF, Ye W, Oswald L, Zhou Y, Kumar A, Brašić J, et al. Dopamine release and subjective responses to IV amphetamine in subjects at risk for alcoholism. Journal of Nuclear Medicine 2005c; 48, (5 abstract book supplement), 73 [abstract]
  • Wong DF, Wagner Jr. HN, Dannals RF, Links JM, Frost JJ, Ravert HT, et al. Effects of age on dopamine and serotonin receptors measured by positron tomography in the living human brain. Science 1984; 226: 1393–1396
  • Wong DF, Wagner Jr. HN, Tune LE, Dannals RF, Pearlson GD, Links JM, et al. Positron emission tomography reveals elevated D2 dopamine receptors in drug naïve schizophrenics. Science 1986; 234: 1558–1563
  • Wong DF, Zhou Y, Brašić J, Catafau A, Offord S, Dogan AS, et al. Cerebral H1-receptor pattern at baseline and after a single dose of the antihistamine fexofenadine. Abstract Book, American College of Asthma, Allergy, and Immunology, Annual Meeting. Seattle November 3–8, 2000, (p. 40, Abstract P57)
  • Wong DF, Ye W, Thomas M, Brašić JR, Nandi A, Alexander M, et al. Differential DAT occupancy of methylphenidate hydrochloride (CONCERTA®) and immediate-release (Ritalin®) compared in subjects with substance abuse. Abstracts of the 67th Annual Scientific Meeting of the College on Problems of Drug Dependence (CPDD). College on Problems of Drug Dependence (CPDD) [abstract], Orlando, Florida 2005d
  • Ye W, Zhou Y, Cantilina L, Kahn R, Brašić J, Alexander M, et al. Dose escalating assessment of potential interactions between intravenous cocaine and RPR 102681. Journal of Nuclear Medicine 2005; 48(5 abstract book supplement)72–73, abstract
  • Zhou Y, Brašić J, Dogan AS, Ye W, Crabb AH, Hilton J, et al. A robust parametric imaging algorithm to quantify serotonin receptor and transporter binding in human brain using 11C-MDL 100,907 and (+)11C-MCN 5652 dynamic PET. Journal of Nuclear Medicine 2004a; 45(5 supplement)395–396, abstract
  • Zhou Y, Brašić J, Endres CJ, Kuwabara H, Kimes A, Contoreggi C, et al. Binding potential image based statistical mapping for detection of dopamine release by [11C]raclopride dynamic PET. NeuroImage 2002a; 16(3), (Part 2 of 2 Parts), S91 [abstract]
  • Zhou Y, Brašić JR, Fan H, Maini A, Wong DF. Kinetic analysis and parametric imaging of [123I](S)-5-iodo-3-(2-azetidinylmethoxy)pyridine (5IA) for subjects with Rett syndrome. 3rd Annual Rett Syndrome Symposium June 17–19, 2002. Inn at The Colonnade, Baltimore, Maryland 2002b; 31–32, Cincinnati: Rett Syndrome Research Foundation (RSRF) [abstract]
  • Zhou Y, Brašić JR, Musachio JL, Crabb AH, Fan H, Hilton J, Wong DF. Quantification of α4β2 Neuronal Nicotinic Acetylcholine Receptor Binding in Humans with Dynamic Single Photon Emission Computed Tomography (SPECT). 5th Annual Rett Syndrome Symposium, June 28–30, 2004. Inn at the Colonnade, Baltimore, Maryland 2004b; 45, Cincinnati: Rett Syndrome Research Foundation (RSRF) www.rsrf.org [abstract]
  • Zhou Y, Brašić JR, Musachio JL, Zukin SR, Kuwabara H, Crabb AH, et al. Human [123I]5-I-A-85380 dynamic SPECT studies in normals: Kinetic analysis and parametric imaging. Nuclear Science Symposium Conference Record, 2001, Institute of Electrical and Electronics Engineers (IEEE), Incorporated 2001a; 3: 1335–1340
  • Zhou Y, Brašić JR, Ye WG, Dogan AS, Hilton J, Singer HS, et al. Quantification of cerebral serotonin binding in normal controls and subjects with Tourette's syndrome using [C11]MDL 100,907 and (+)[C11]McN 5652 dynamic PET with parametric imaging approach. NeuroImage 2004c; 22(suppl 2)T98–T99, abstract
  • Zhou Y, Chen M, Alexander M, Ye W, Kumar A, Brašić JR, et al. Evaluation a generalized reference tissue model for quantification of [11C]raclopride dynamic PET with bolus plus continuous tracer infusion and amphetamine challenge. Journal of Nuclear Medicine 2005a; 48, (5 abstract book supplement), p. 53 [abstract]
  • Zhou Y, Chen MK, Endres CJ, Ye W, Brašić JR, Alexander M, et al. An extended simplified reference tissue model for the quantification of dynamic PET with amphetamine challenge. Neuroimage 2006; 33: 550–563
  • Zhou Y, Endres C, Dogan S, Brašić J, Huang SC, Wong DF. A new linear parametric imaging algorithm derived from a simplified reference tissue model for D2-receptor dynamic PET studies. Journal of Cerebral Blood Flow and Metabolism 2001b; 21((suppl 1)), S526 [abstract]
  • Zhou Y, Endres CJ, Brašić JR, Huang S-C, Wong DF. Linear regression with spatial constraint to generate parametric images of ligand-receptor dynamic PET studies with a simplified reference tissue model. NeuroImage 2003a; 18: 975–989
  • Zhou Y, Endres CJ, Dogan AS, Brašić JR, Wong DF, Huang S-C. A new linear parametric imaging algorithm derived from a simplified reference tissue model for ligand-receptor dynamic PET studies. Brain imaging using PET, M. Senda, Y. Kimura, P. Herscovitch. Academic Press, Amsterdam 2002c; 33–39
  • Zhou Y, Maini A, Brašić JR, Dogan S, Lee JS, Alexander M, et al. Detection of physiological effects of pharmacological challenges in human dynamic PET studies by parametric imaging and statistical moment analysis. Journal of Nuclear Medicine 2003b; 44(5 supplement)14
  • Zhou Y, Ye W, Brašić JR, Alexander M, Hilton J, Wong DF. Spectral analysis with a minimal basis functions approach for quantification of ligand-receptor dynamic PET study. Journal of Cerebral Blood Flow & Metabolism 2005b; 25: S634–S634, abstract
  • Ziolko SK, Weissfeld LA, Klunk WE, Mathis CA, Hoge JA, Lopresti BJ, et al. Evaluation of voxel-based methods for the statistical analysis of PIB PET amyloid imaging studies in Alzheimer's disease. NeuroImage 2006; 33: 94–102

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