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Review Article

Women and MDMA: particularities of gender and sex

ORCID Icon, ORCID Icon, ORCID Icon & ORCID Icon
Pages 461-467 | Received 12 Jun 2023, Accepted 18 Aug 2023, Published online: 23 Aug 2023

References

  • Baggott, M. J., Garrison, K. J., Coyle, J. R., Galloway, G. P., Barnes, A. J., Huestis, M. A., & Mendelson, J. E. (2016). MDMA impairs response to water intake in healthy volunteers. Advances in Pharmacological Sciences, 2016, 2175896–2175811. https://doi.org/10.1155/2016/2175896.
  • Barenys, M., Reverte, I., Masjosthusmann, S., Gómez-Catalán, J., & Fritsche, E. (2020). Developmental neurotoxicity of MDMA. A systematic literature review summarized in a putative adverse outcome pathway. Neurotoxicology, 78, 209–241. https://doi.org/10.1016/j.neuro.2019.12.007.
  • Basedow, L. A., Wiedmann, M. F., Roessner, V., Golub, Y., & Kuitunen-Paul, S. (2022). Coping motives mediate the relationship between PTSD and MDMA use in adolescents with substance use disorders. Addiction Science & Clinical Practice, 17(1), 46. https://doi.org/10.1186/s13722-022-00329-y.
  • Durdle, H., Lundahl, L. H., Johanson, C. E., & Tancer, M. (2008). Major depression: The relative contribution of gender, MDMA, and cannabis use. Depression and Anxiety, 25(3), 241–247. https://doi.org/10.1002/da.20297.
  • Fonseca, F., Robles-Martínez, M., Tirado-Muñoz, J., Alías-Ferri, M., Mestre-Pintó, J. I., Coratu, A. M., & Torrens, M. (2021). A gender perspective of addictive disorders. Current Addiction Reports, 8(1), 89–99. https://doi.org/10.1007/s40429-021-00357-9.
  • Fonsart, J., Menet, M.-C., Debray, M., Hirt, D., Noble, F., Scherrmann, J.-M., & Declèves, X. (2009). Sprague–Dawley rats display sex-linked differences in the pharmacokinetics of 3, 4-methylenedioxymethamphetamine (MDMA) and its metabolite 3, 4-methylenedioxyamphetamine (MDA). Toxicology and Applied Pharmacology, 241(3), 339–347. https://doi.org/10.1016/j.taap.2009.09.008.
  • Green, A. R., Shea, E. O., & Colado, M. I. (2004). A review of the mechanisms involved in the acute MDMA (ecstasy) -induced hyperthermic response. European Journal of Pharmacology, 500(1-3), 3–13. https://doi.org/10.1016/j.ejphar.2004.07.006.
  • Holdcroft, A. (2007). Gender bias in research: how does it affect evidence based medicine? Journal of the Royal Society of Medicine, 100(1), 2–3. https://doi.org/10.1177/014107680710000102.
  • Hysek, C. M., Schmid, Y., Simmler, L. D., Domes, G., Heinrichs, M., Eisenegger, C., Preller, K., Quednow, B. B., & Liechti, M. E. (2014). MDMA enhances emotional empathy and prosocial behavior. Social Cognitive and Affective Neuroscience, 9(11), 1645–1652. https://doi.org/10.1093/scan/nst161.
  • Illingworth, B. J., Lewis, D. J., Lambarth, A. T., Stocking, K., Duffy, J. M., Jelen, L. A., & Rucker, J. J. (2021). A comparison of MDMA-assisted psychotherapy to non-assisted psychotherapy in treatment-resistant PTSD: A systematic review and meta-analysis. Journal of Psychopharmacology (Oxford, England), 35(5), 501–511. https://doi.org/10.1177/0269881120965915.
  • Íncera-Fernández, D., Román, F. J., & Gámez-Guadix, M. (2022). Risky sexual practices, sexually transmitted infections, motivations, and mental health among heterosexual women and men who practice sexualized drug use in Spain. International Journal of Environmental Research and Public Health, 19(11), 6387. https://doi.org/10.3390/ijerph19116387.
  • Kandall, S. R. (2010). Women and drug addiction: A historical perspective. Journal of Addictive Diseases, 29(2), 117–126. https://doi.org/10.1080/10550881003684491.
  • Kirkpatrick, M. G., Baggott, M. J., Mendelson, J. E., Galloway, G. P., Liechti, M. E., Hysek, C. M., & de Wit, H. (2014). MDMA effects consistent across laboratories. Psychopharmacology, 231(19), 3899–3905. https://doi.org/10.1007/s00213-014-3528-z.
  • Kostick, K. M., & Schensul, J. J. (2018). The role of Ecstasy (MDMA) in managing intimacy and conflict in stable relationships. Culture, Health & Sexuality, 20(10), 1071–1086. https://doi.org/10.1080/13691058.2018.1475682.
  • Liechti, M. E., Kunz, I., & Kupferschmidt, H. (2005). Acute medical problems due to Ecstasy use. Case-series of emergency department visits. Swiss Medical Weekly, 135(43-44), 652–657. https://doi.org/10.4414/smw.2005.11231.
  • McElrath, K. (2005). MDMA and sexual behavior: Ecstasy users’ perceptions about sexuality and sexual risk. Substance Use & Misuse, 40(9-10), 1461–1477. https://doi.org/10.1081/JA-200066814.
  • Moritz, M. L., Kalantar-Zadeh, K., & Ayus, J. C. (2013). Ecstasy-associated hyponatremia: why are women at risk? Nephrology, Dialysis, Transplantation: Official Publication of the European Dialysis and Transplant Association - European Renal Association, 28(9), 2206–2209. https://doi.org/10.1093/ndt/gft192.
  • Müller, F., Brandle, R., Liechti, M. E., & Borgwardt, S. (2019). Neuroimaging of chronic MDMA (“ecstasy”) effects: a meta-analysis. Neuroscience and Biobehavioral Reviews, 96, 10–20. https://doi.org/10.1016/j.neubiorev.2018.11.004.
  • National Institute on Drug Abuse. (2016). Substance use in women. NIDA. http://www.drugabuse.gov/publications/research-reports/substance-use-in-women/summary
  • National Institute on Drug Abuse. (2020). Substance use in women research report. NIDA. https://nida.nih.gov/download/18910/substance-use-in-women-research-report.pdf
  • Neff, M. (2018). Usages de drogues au féminin et production du savoir académique. Déviance et Société, 42(3), 569–595. https://doi.org/10.3917/ds.423.0569.
  • Reneman, L., Booij, J., de Bruin, K., Reitsma, J. B., de Wolff, F. A., Gunning, W. B., den Heeten, G. J., & van den Brink, W. (2001). Effects of dose, sex, and long-term abstention from use on toxic effects of MDMA (ecstasy) on brain serotonin neurons. Lancet (London, England), 358(9296), 1864–1869. https://doi.org/10.1016/S0140-6736(01)06888-X.
  • Rigg, K. K., & Mills, A. (2020). Sexual risk behaviors among African Americans who use MDMA (molly/ecstasy): Implications for HIV prevention. Social Work in Public Health, 35(5), 282–292. https://doi.org/10.1080/19371918.2020.1781013.
  • Singer, L. T., Moore, D. G., Min, M. O., Goodwin, J., Turner, J. J. D., Fulton, S., & Parrott, A. C. (2012). One-year outcomes of prenatal exposure to MDMA and other recreational drugs. Pediatrics, 130(3), 407–413. https://doi.org/10.1542/peds.2012-0666.
  • Singer, L. T., Moore, D. G., Min, M. O., Goodwin, J., Turner, J. J. D., Fulton, S., & Parrott, A. C. (2016). Motor delays in MDMA (ecstasy) exposed infants persist to 2years. Neurotoxicology and Teratology, 54, 22–28. https://doi.org/10.1016/j.ntt.2016.01.003.
  • Simmler, L. D., Hysek, M., & Liechti, M. E. (2011). Sex differences in the effects of MDMA (ecstasy) on plasma copeptin in healthy subjects. The Journal of Clinical Endocrinology and Metabolism, 96(9), 2844–2850. https://doi.org/10.1210/jc.2011-1143.
  • Smid, M. C., Metz, T. D., & Gordon, A. J. (2019). Stimulant use in pregnancy–An under-recognized epidemic among pregnant women. Clinical Obstetrics and Gynecology, 62(1), 168–184. https://doi.org/10.1097/GRF.0000000000000418.
  • Studerus, E., Vizeli, P., Harder, S., Ley, L., & Liechti, M. E. (2021). Prediction of MDMA response in healthy humans: A pooled analysis of placebo-controlled studies. Journal of Psychopharmacology (Oxford, England), 35(5), 556–565. https://doi.org/10.1177/0269881121998322.
  • UNODC. (2022). World Drug Report 2022. United Nations publication. https://www.unodc.org/unodc/data-and-analysis/world-drug-report-2022.html
  • Vizeli, P., & Liechti, M. E. (2017). Safety pharmacology of acute MDMA administration in healthy subjects. Journal of Psychopharmacology (Oxford, England), 31(5), 576–588. https://doi.org/10.1177/0269881117691569.

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