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Article

Pulsed versus continuous terbinafine dosing in the treatment of dermatophyte onychomycosis

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Pages 315-320 | Received 20 Nov 2003, Accepted 01 Jun 2004, Published online: 12 Jul 2009

References

  • Baudraz-Rosselet F, Rakosi T, Wili PB, Kenzelmann R, Treatment onychomycosis with terbinafine. Br J Dermatol (1992) 126 (suppl 39): 40–6.
  • Van der Schroeff JG, Girkel PKDS, Crijns MB et al, A randomized treatment duration finding study of terbinafine in onychomycosis. Br J Dermatol (1992) 126 (suppl): 36–9.
  • Villars VV, Jones TC, Special features of the clinical use of terbinafine in the treatment of fungal diseases. Br J Dermatol (1992) 126 (suppl 39): 61–9.
  • Alpsoy E, Yilmaz E, Basaran E, Intermittent therapy with terbinafine for dermatophyte toe onychomycosis: a new approach. J Dermatol (1996) 23: 259–62.
  • Tosti A, Piraccini BM, Stinchi C et al, Treatment of dermatophyte nail infections: an open randomized study comparing intermittent terbinafine therapy with contin- uous terbinafine treatment and intermittent itraconazole therapy. J Am AcadDermatol (1996a) 34: 595–600.
  • Gupta AK, Lynde CW, Konnikov N, Single-blind, randomized, prospective study of sequential itraconazole and terbinafine pulse compared with terbinafine pulse for the treatment of toenail onychomycosis. J Am Acad Dermatol (2001) 44: 485–91.
  • Dixon WJ (Chief editor). BMDP statistical software. University of California Press: Los Angeles, CA, 1993.
  • Hall M, Monka C, Krupp P, O’Sullivan D, Safety of oral terbinafine; results of a postmarketing surveillance study in 25,884 patients. Arch Dermatol (1997) 133: 1213–19.
  • Villars V, Jones TC, Clinical efficacy and tolerability of terbinafine (Lamisil) – a new topical and systemic fungicidal drug for treatment of dermatomycoses. Clin Exp Dermatol (1989) 14: 124–7.
  • Korting HC, Schafer-Korting M, Is tinea unguium still widely incurable? A review three decades after the introduction of griseofulvin. Arch Dermatol (1992) 128: 243–8.
  • Brautigam M, Nolting S, Schopf RE et al, German randomized double-blind multicentre comparison of terbinafine and itraconazole in the treatment of toenail tinea infection. Br Med J (1996) 134 (suppl 46): 18–21.
  • Brautigam M, Terbinafine vs itraconazole: a controlled clinical comparison in onychomycosis of the toenails. J Am Acad Dermatol (1998) 38: S53–6.
  • De Backer M, De Vroey C, Lesaffre E et al, Twelve weeks of continuous oral therapy for toenail onychomycosis caused by dermatophytes: a double-blind comparative trial of terbinafine 250 mg/day versus itraconazole 200 mg/day. J Am Acad Dermatol (1998) 38: S57–63.
  • Arikian SR, Einarson TR, Kobelt-Nguyen G et al, A multinational pharmacoeconomic analysis of oral thera- pies for onychomycosis. Br J Dermatol (1994) 130 (suppl 43): 35–44.
  • Einarson TR, Arikian SR, Shear NH, Cost-effectiveness analysis for onychomycosis therapy in Canada from a government perspective. Br J Dermatol (1994) 130 (suppl 43): 32–4.
  • Marchetti A, Piech CT, McGhan WF et al, Pharmaco- economic analysis of oral therapies for onychomycosis: a US model. Clin Ther (1996) 18: 757–77.
  • Gupta AK, Pharmacoeconomic analysis of oral anti- fungal therapies used to treat dermatophyte onychomy- cosis of the toenails. A US analysis. Pharmacoeconomics (1998) 13: 243–56.
  • Angello JT, Voytovich RM, Jan SA, A cost/efficacy analysis of oral antifungals indicated for the treatment of onychomycosis: griseofulvin, itraconazole, and terbina- fine. Am J Manag Care (1997) 3: 443–50.
  • La Placa M Jr, Stinchi C, Venturo N et al, Terbinafine vs griseofulvin in the treatment of onychomycosis due to dermatophytes. G Ital Dermatol Venereol (1994) 129: 19–22.
  • Cribier B, Grosshans E, Efficacite et tolerance de la terbinafine (Lamisil1) dans une serie de 50 onychomy- coses a dermatophytes. Ann Derm Venereol (1994) 121: 15–20.
  • Goodfields MJD, Short-duration therapy with terbinafine for dermatophyte onychomycosis: a multicentre trial. Br J Dermatol (1992) 126 (suppl 39): 33–5.
  • Faergemann J, Zehender H, Millerioux L, Levels of terbinafine in plasma, stratum corneum, dermis- epidermis (without stratum corneum), hair and nails during and after 250 mg terbinafine orally once daily for 7 and 14 days. Clin Exp Dermatol (1994) 19: 121–6.
  • Leyden J, Pharmacokinetics and pharmacology of terbinafine and itraconazole. J Am Acad Dermatol (1998) 38: S42–7.
  • Finlay AY, Parmacokinetics of terbinafine in the nail. Br J Dermatol (1992) 126 (suppl 39): 28–32.
  • Schatz F, Brautigam M, Dobrowolski E et al, Nail incorporation kinetics of terbinafine in onychomycosis patients. Clin Exp Dermatol (1995) 20: 377–83.
  • Debruyne D, Coquerel A, Pharmacokinetics of antifungal agents in onychomycoses. Clin Pharmacokinet (2001) 40: 441–72.
  • Roberts DT, The clinical efficacy of terbinafine in the treatment of fungal infections of nails. Rev Contemp Pharmacother (1997) 8: 299–312.
  • Glyn E, Evans V, Sigurgeirsson B, Double-blind, randomized study of continuous terbinafine compared with intermittent itraconazole in treatment of toenail onychomycosis. Br Med J (1999) 318: 1031–5.
  • Gupta AK, Konnikov N, Lynde CW, Single-blind, randomized, prospective study on terbinafine and itraconazole for treatment of dermatophyte toenail onychomycosis in the elderly. J Am Acad Dermatol (2001) 44: 479–84.
  • Shuster S, Munro CS, Single-dose treatment of fungal nail disease. Lancet (1992) 339: 1066.
  • Gupta AK, Adam B, Terbinafine pulse therapy is effective in tinea capitis. Pediatr Dermatol (1998) 15: 56–8.
  • Tosti A, Piraccini BM, Stinchi C, Colombo MD, Relapses of onychomycosis after successful treatment with systemic antifungals: a three-year follow up. Dermatology (1998) 197: 162–6.

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