A consensus on the use of daylight photodynamic therapy in the UK

References

• Salasche SJ. Epidemiology of actinic keratoses and squamous cell carcinoma. J Am Acad Dermatol. 2000;42:4–7.
   PubMed Web of Science ®Google Scholar
• Franceschi S, Levi F, Randimbison L, La Vecchia C. Site distribution of different types of skin cancer: new aetiological clues. Int J Cancer. 1996;67:24–8.
   PubMed Web of Science ®Google Scholar
• Dodds A, Chia A, Shumack S. Actinic keratosis: rationale and management. Dermatol Ther (Heidelb). 2014;4:11–31.
   PubMedGoogle Scholar
• de Berker D, McGregor JM, Hughes BR. British Association of Dermatologists Therapy Guidelines and Audit Subcommittee. Guidelines for the management of actinic keratoses. Br J Dermatol. 2007;156:222–30.
   PubMed Web of Science ®Google Scholar
• Ulrich C, Arnold R, Frei U, et al. Skin changes following organ transplantation: an interdisciplinary challenge. Dtsch Arztebl Int. 2014;111:188–94.
   PubMed Web of Science ®Google Scholar
• Flohil SC, van der Leest RJ, Dowlatshahi EA, et al. Prevalence of actinic keratosis and its risk factors in the general population: the Rotterdam Study. J Invest Dermatol. 2013;133:1971–8.
   PubMed Web of Science ®Google Scholar
• Stockfleth E, Ulrich C, Meyer T, Christophers E. Epithelial malignancies in organ transplant patients: clinical presentation and new methods of treatment. In Dummer PDR, Nestle PDFO, Burg PDG, editors. Cancers of the Skin [Internet]. Berlin Heidelberg: Springer, 2002 [cited 2015 Feb 10]. p 251–8. Available from http://link.springer.com/chapter/10.1007/978-3-642-59410-6_30.
   Google Scholar
• Euvrard S, Kanitakis J, Claudy A. Skin cancers after organ transplantation. N Engl J Med. 2003;348:1681–91.
   PubMed Web of Science ®Google Scholar
• Wlodek C, Ali FR, Lear JT. Use of photodynamic therapy for treatment of actinic keratoses in organ transplant recipients. BioMed Res Int [Internet]. 2013;2013. doi:10.1155/2013/349526.
   PubMed Web of Science ®Google Scholar
• Morton CA, McKenna KE, Rhodes LE. British Association of Dermatologists Therapy Guidelines and Audit Subcommittee and the British Photodermatology Group. Guidelines for topical photodynamic therapy: update. Br J Dermatol. 2008;159:1245–66.
   PubMed Web of Science ®Google Scholar
• Metvix SPC [Internet] [cited 2015 May 2]. Available from http://www.medicines.org.uk/emc/medicine/11913.
   Google Scholar
• Ameluz SPC [Internet] [cited 2015 May 2]. Available from http://www.medicines.org.uk/emc/medicine/27817.
   Google Scholar
• Lehmann P. Methyl aminolaevulinate-photodynamic therapy: a review of clinical trials in the treatment of actinic keratoses and nonmelanoma skin cancer. Br J Dermatol. 2007;156:793–801.
   PubMed Web of Science ®Google Scholar
• NICE. Photodynamic Therapy for Non-Melanoma Skin Tumours (including Premalignant and Primary Non-Metastatic Skin Lesions) – Guidance And Guidelines, 2006. Available from http://www.nice.org.uk/guidance/ipg155. Accessed April 8, 2015.
   Google Scholar
• Primary Care Dermatology Society. Actinic Keratosis (Solar Keratosis), 2014. Available from http://www.pcds.org.uk/clinical-guidance/actinic-keratosis-syn.-solar-keratosis. Accessed April 8, 2015.
   Google Scholar
• Rud E, Gederaas O, Høgset A, Berg K. 5-aminolevulinic acid, but not 5-aminolevulinic acid esters, is transported into adenocarcinoma cells by system BETA transporters. Photochem Photobiol. 2000;71:640–7.
   PubMed Web of Science ®Google Scholar
• Wiegell SR, Haedersdal M, Wulf HC. Cold water and pauses in illumination reduces pain during photodynamic therapy: a randomized clinical study. Acta Derm Venereol. 2009;89:145–9.
   PubMed Web of Science ®Google Scholar
• Halldin CB, Gonzalez H, Wennberg AM, Lepp M. Patients' experiences of pain and pain relief during photodynamic therapy on actinic keratoses: an interview study. Acta Derm Venereol. 2013;93:433–7.
   PubMed Web of Science ®Google Scholar
• Arits AH, van de Weert MM, Nelemans PJ, Kelleners-Smeets NW. Pain during topical photodynamic therapy: uncomfortable and unpredictable. J Eur Acad Dermatol Venereol. 2010;24:1452–7.
   PubMed Web of Science ®Google Scholar
• Cottrell WJ, Paquette AD, Keymel KR, et al. Irradiance-dependent photobleaching and pain in delta-aminolevulinic acid-photodynamic therapy of superficial basal cell carcinomas. Clin Cancer Res. 2008;14:4475–83.
   PubMed Web of Science ®Google Scholar
• Attili SK, Lesar A, McNeill A, et al. An open pilot study of ambulatory photodynamic therapy using a wearable low-irradiance organic light-emitting diode light source in the treatment of nonmelanoma skin cancer. Br J Dermatol. 2009;161:170–3.
   PubMed Web of Science ®Google Scholar
• Wiegell SR, Haedersdal M, Philipsen PA, et al. Continuous activation of PpIX by daylight is as effective as and less painful than conventional photodynamic therapy for actinic keratoses; a randomized, controlled, single-blinded study. Br J Dermatol. 2008;158:740–6.
   PubMed Web of Science ®Google Scholar
• Wiegell SR, Haedersdal M, Eriksen P, Wulf HC. Photodynamic therapy of actinic keratoses with 8% and 16% methyl aminolaevulinate and home-based daylight exposure: a double-blinded randomized clinical trial. Br J Dermatol. 2009;160:1308–14.
   PubMed Web of Science ®Google Scholar
• Wiegell SR, Fabricius S, Stender IM, et al. A randomised, multicentre study of directed daylight exposure times of 1½ vs. 2½ h in daylight-mediated photodynamic therapy with methyl aminolaevulinate in patients with multiple thin actinic keratoses of the face and scalp. Br J Dermatol. 2011;164:1083–90.
   PubMed Web of Science ®Google Scholar
• Wiegell SR, Fabricius S, Gniadecka M, et al. Daylight-mediated photodynamic therapy of moderate to thick actinic keratoses of the face and scalp: a randomised multicentre study. Br J Dermatol. 2012;166:1327–32.
   PubMed Web of Science ®Google Scholar
• Wiegell SR, Fabricius S, Heydenreich J, et al. Weather conditions and daylight-mediated photodynamic therapy: protoporphyrin IX-weighted daylight doses measured in six geographical locations. Br J Dermatol. 2013;168:186–91.
   PubMed Web of Science ®Google Scholar
• Braathen LR. Daylight photodynamic therapy in private practice in Switzerland: gain without pain. Acta Derm Venereol. 2012;92:652–3.
   PubMed Web of Science ®Google Scholar
• Pérez-Pérez L, García-Gavín J, Gilaberte Y. Daylight-mediated photodynamic therapy in Spain: advantages and disadvantages. Actas Dermosifiliogr. 2014;105:663–74.
   PubMedGoogle Scholar
• Fai D, Romano I, Fai C, et al. Daylight photodynamic therapy with methyl aminolaevulinate in patients with actinic keratoses: a preliminary experience in southern Italy. G Ital Dermatol Venereol. 2016;151:154–9.
   PubMed Web of Science ®Google Scholar
• Grinblat BM, Festa Neto C, Sanches JA, Jr, et al. Daylight photodynamic therapy for actinic keratoses in São Paulo, Brazil. Photodermatol Photoimmunol Photomed. 2015;31:54–6.
   PubMed Web of Science ®Google Scholar
• Rubel DM, Spelman L, Murrell DF, et al. Daylight photodynamic therapy with methyl aminolevulinate cream as a convenient, similarly effective, nearly painless alternative to conventional photodynamic therapy in actinic keratosis treatment: a randomised controlled trial. Br J Dermatol. 2014;171:1164–71.
   PubMed Web of Science ®Google Scholar
• Lacour J, Ulrich C, Gilaberte Y, et al. Daylight photodynamic therapy with methyl aminolevulinate cream is effective and nearly painless in treating actinic keratoses: a randomised, investigator-blinded, controlled, phase III study throughout Europe. J Eur Acad Dermatol Venereol. 2015;29:2342–8.
   PubMed Web of Science ®Google Scholar
• Wiegell SR, Wulf HC, Szeimies RM, et al. Daylight photodynamic therapy for actinic keratosis: an international consensus: International Society for Photodynamic Therapy in Dermatology. J Eur Acad Dermatol Venereol. 2012;26:673–9.
   PubMed Web of Science ®Google Scholar
• Sakamoto FH, Torezan L, Anderson RR. Photodynamic therapy for acne vulgaris: a critical review from basics to clinical practise: Part II. Understanding parameters for acne treatment with photodynamic therapy. J Am Acad Dermatol. 2010;63:195–211.
   PubMed Web of Science ®Google Scholar
• Wulf HC. Optimising the amount of Metvix in daylight PDT. Euro-PDT 13th Annual Congress; Madrid, Spain; May 31st–June 1st, 2013.
   Google Scholar
• Morton CA, Wulf HC, Szeimies RM, et al. Practical approach to the use of daylight photodynamic therapy with topical methyl aminolevulinate for actinic keratosis: a European consensus. J Eur Acad Dermatol Venereol. 2015;29:1718–23.
   PubMed Web of Science ®Google Scholar
• Lerche C, Heerfordt I, Heydenreich J, Wulf H. Alternatives to outdoor daylight illumination for photodynamic therapy-use of greenhouses and artificial light sources. Int J Mol Sci. 2016;17:309.
   PubMed Web of Science ®Google Scholar