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Journal of Dermatological Treatment Volume 29, 2018 - Issue 1
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Psoriasis

Topical 0.25% desoximetasone spray efficacy for moderate to severe plaque psoriasis: a randomized clinical trial

Mohammed D. SaleemDepartment of Dermatology, Wake Forest School of Medicine, Center for Dermatology Research, Winston-Salem, NC, USA; Correspondence[email protected]
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,
Deborah NegusDepartment of Dermatology, Wake Forest School of Medicine, Center for Dermatology Research, Winston-Salem, NC, USA; View further author information
&
Steven R. FeldmanDepartment of Dermatology, Wake Forest School of Medicine, Center for Dermatology Research, Winston-Salem, NC, USA; ;Department of Pathology, Wake Forest School of Medicine, Winston-Salem, NC, USA; ;Department of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USAView further author information
Pages 32-35 | Received 27 Jan 2017, Accepted 26 Mar 2017, Published online: 30 May 2017

References

  • Kerkhof VD, Peter CM, Nestle FO. Psoriasis. In Bolognia JL, Jorizzo JL, Schaffer JV, eds. Dermatology. 3rd ed. Vol. 1. Philadelphia: Elsevier, 2015. p 135–56.
  • Huang KE, Davis SA, Cantrell J, et al. Increasing use of non-traditional vehicles for psoriasis and other inflammatory skin conditions. Dermatol Online J. 2014;20. Available from http://www.ncbi.nlm.nih.gov/pubmed/25244174
  • Brown KK, Rehmus WE, Kimball AB. Determining the relative importance of patient motivations for nonadherence to topical corticosteroid therapy in psoriasis. J Am Acad Dermatol. 2006;55:607–13.
  • Housman TS, Mellen BG, Rapp SR, et al. Patients with psoriasis prefer solution and foam vehicles: a quantitative assessment of vehicle preference. Cutis. 2002;70:327–32.
  • Brodell R, Preston N. Improvement in signs and symptoms of plaque psoriasis after 1 week of treatment with clobetasol propionate 0.05% spray. J Drugs Dermatol. 2012;11:1455–9.
  • Menter MA, Caveney SW, Gottschalk RW. Impact of clobetasol propionate 0.05% spray on health-related quality of life in patients with plaque psoriasis. J Drugs Dermatol. 2012;11:1348–54.
  • Kircik L, Lebwohl MG, Del Rosso JQ, et al. Clinical study results of desoximetasone spray, 0.25% in moderate to severe plaque psoriasis. J Drugs Dermatol. 2013;12:1404–10.
  • Carroll CL, Feldman SR, Camacho FT, Balkrishnan R. Better medication adherence results in greater improvement in severity of psoriasis. Br J Dermatol. 2004;151:895–7.
  • Franz TJ, Lehman PA, Feldman SR, Spellman MC. Bioavailability of clobetasol propionate in different vehicles. Skin Pharmacol Appl Skin Physiol. 2003;16:212–6.
  • Housman TS, Keil KA, Mellen BG, et al. The use of 0.25% zinc pyrithione spray does not enhance the efficacy of clobetasol propionate 0.05% foam in the treatment of psoriasis. J Am Acad Dermatol. 2003;49:79–82.

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