Randomized trial of electrodynamic microneedling combined with 5% minoxidil topical solution for treating androgenetic alopecia in Chinese males and molecular mechanistic study of the involvement of the Wnt/β-catenin signaling pathway

References

• Xu F, Sheng YY, Mu ZL, et al. Prevalence and types of androgenetic alopecia in Shanghai, China: a community-based study. Br J Dermatol. 2009;160(3):629–632.
   PubMed Web of Science ®Google Scholar
• Kaliyadan F, Nambiar A, Vijayaraghavan S. Androgenetic alopecia: an update. Indian J Dermatol Venereol Leprol. 2013;79(5):613–625.
   PubMed Web of Science ®Google Scholar
• Ho B-Y, Ho EXP, Chu CW, et al. Microbiome in the hair follicle of androgenetic alopecia patients. PLOS One. 2019;14(5):e0216330.
   PubMed Web of Science ®Google Scholar
• Katzer T, Leite JA, Beck R, et al. Physiopathology and current treatments of androgenetic alopecia: going beyond androgens and anti-androgens. Dermatol Ther. 2019;32(5):e13059.
   PubMed Web of Science ®Google Scholar
• Genander M, Peter JC, Ramsköld D, et al. BMP signaling and its pSMAD1/5 target genes differentially regulate hair follicle stem cell lineages. Cell Stem Cell. 2014;15(5):619–633.
   PubMed Web of Science ®Google Scholar
• Toshima S, Kurihara Y, Wang EHC, et al. Alopecia areata multiplex following autologous dermal micrograft injection for treatment of androgenetic alopecia. J Eur Acad Dermatol Venereol. 2019;33(11):e397–e399.
   PubMed Web of Science ®Google Scholar
• Jimenez-Cauhe J, Saceda-Corralo D, Rodrigues-Barata R, et al. Effectiveness and safety of low-dose oral minoxidil in male androgenetic alopecia. J Am Acad Dermatol. 2019;81(2):648–649.
   PubMed Web of Science ®Google Scholar
• Dhariwala MY, Ravikumar P. An overview of herbal alternatives in androgenetic alopecia. J Cosmet Dermatol. 2019;18(4):966–975.
   PubMed Web of Science ®Google Scholar
• Jha AK, Vinay K. Androgenetic alopecia and microneedling: every needling is not microneedling. J Am Acad Dermatol. 2019;81(2):e43–e44.
   PubMed Web of Science ®Google Scholar
• Bayat M, Yazdanpanah MJ, Hamidi Alamdari D, et al. The effect of platelet-rich plasma injection in the treatment of androgenetic alopecia. J Cosmet Dermatol. 2019;18(6):1624–1628.
   PubMed Web of Science ®Google Scholar
• Lotti T, Goren A, Verner I, et al. Platelet rich plasma in androgenetic alopecia: a systematic review. Dermatol Ther. 2019;32(3):e12837.
   PubMed Web of Science ®Google Scholar
• Ito M, Yang Z, Andl T, et al. Wnt-dependent de novo hair follicle regeneration in adult mouse skin after wounding. Nature. 2007;447(7142):316–320.
   PubMed Web of Science ®Google Scholar
• Premanand A, Reena Rajkumari B. Androgen modulation of Wnt/β-catenin signaling in androgenetic alopecia. Arch Dermatol Res. 2018;310(5):391–399.
   PubMed Web of Science ®Google Scholar
• Blume-Peytavi U, Lonnfors S, Hillmann K, et al. A randomized double-blind placebo-controlled pilot study to assess the efficacy of a 24-week topical treatment by latanoprost 0.1% on hair growth and pigmentation in healthy volunteers with androgenetic alopecia. J Am Acad Dermatol. 2012;66(5):794–800.
   PubMed Web of Science ®Google Scholar
• Rizer RL, Stephens TJ, Herndon JH, et al. A marine protein-based dietary supplement for subclinical hair thinning/loss: results of a multisite, double-blind, placebo-controlled clinical trial. Int J Trichol. 2015;7(4):156–166.
   PubMedGoogle Scholar
• Bao L, Gong L, Guo M, et al. Randomized trial of electrodynamic microneedle combined with 5% minoxidil topical solution for the treatment of Chinese male Androgenetic alopecia. J Cosmet Laser Ther. 2020;22(1):1–7.
   PubMed Web of Science ®Google Scholar
• Dhurat R, Sukesh MS, Avhad G, et al. A randomized evaluator blinded study of effect of microneedling in androgenetic alopecia: a pilot study. Int J Trichol. 2013;5(1):6–11.
   PubMedGoogle Scholar
• Harris AG, Murrel DF. Combining microneedling and triamcinolone-a novel way to increase the tolerability of intralesional corticosteroid delivery in children with alopecia areata. Aust J Dermatol. 2015;56:40–41.
   Web of Science ®Google Scholar
• Bai WL, Zhao SJ, Wang ZY, et al. LncRNAs in secondary hair follicle of cashmere goat: identification, expression, and their regulatory network in Wnt signaling pathway. Anim Biotechnol. 2018;29(3):199–211.
   PubMed Web of Science ®Google Scholar
• Bejaoui M, Villareal MO, Isoda H. β-catenin-mediated hair growth induction effect of 3,4,5-tri-O-caffeoylquinic acid. Aging (Albany, NY). 2019;11(12):4216–4237.
   PubMedGoogle Scholar
• Zhao B, Chen Y, Yang N, et al. miR-218-5p regulates skin and hair follicle development through Wnt/β-catenin signaling pathway by targeting SFRP2. J Cell Physiol. 2019;234(11):20329–20341.
   PubMed Web of Science ®Google Scholar
• Wang HD, Yang L, Yu XJ, et al. Immunolocalization of β-catenin and Lef-1 during postnatal hair follicle development in mice. Acta Histochem. 2012;114(8):773–778.
   PubMed Web of Science ®Google Scholar
• Doumpas N, Lampart F, Robinson MD, et al. TCF/LEF dependent and independent transcriptional regulation of Wnt/β-catenin target genes. EMBO J. 2019;38(2):e98873.
   PubMed Web of Science ®Google Scholar
• Rognoni E, Gomez C, Pisco AO, et al. Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing. Development. 2016;143(14):2522–2535.
   PubMed Web of Science ®Google Scholar
• Shimomura Y, Christiano AM. Biology and genetics of hair. Annu Rev Genomics Hum Genet. 2010;11:109–132.
   PubMed Web of Science ®Google Scholar
• Zhu K, Xu C, Liu M, et al. Hairless controls hair fate decision via Wnt/β-catenin signaling. Biochem Biophys Res Commun. 2017;491(3):567–570.
   PubMed Web of Science ®Google Scholar
• Higgins CA, Chen JC, Cerise JE, et al. Microenvironmental reprogramming by three-dimensional culture enables dermal papilla cells to induce de novo human hair-follicle growth. Proc Natl Acad Sci USA. 2013;110(49):19679–19688.
   PubMed Web of Science ®Google Scholar
• Li C, Nguyen V, Clark KN, et al. Down-regulation of FZD3 receptor suppresses growth and metastasis of human melanoma independently of canonical WNT signaling. Proc Natl Acad Sci USA. 2019;116(10):4548–4557.
   PubMed Web of Science ®Google Scholar
• Siddique A, Yu B, Khan K, et al. Expression of the Frizzled receptors and their co-receptors in calcified human aortic valves. Can J Physiol Pharmacol. 2018;96(2):208–214.
   PubMed Web of Science ®Google Scholar
• Xia L, Wu L, Bao J, et al. Circular RNA circ-CBFB promotes proliferation and inhibits apoptosis in chronic lymphocytic leukemia through regulating miR-607/FZD3/Wnt/β-catenin pathway. Biochem Biophys Res Commun. 2018;503(1):385–390.
   PubMed Web of Science ®Google Scholar
• Mo D, Jiang P, Yang Y, at al. A tRNA fragment, 5′-tiRNAVal, suppresses the Wnt/β-catenin signaling pathway by targeting FZD3 in breast cancer. Cancer Lett. 2019;457:60–73.
   PubMed Web of Science ®Google Scholar
• Hung BS, Wang X-Q, Cam GR, et al. Characterization of mouse frizzled-3 expression in hair follicle development and identification of the human homolog in keratinocytes. J Invest Dermatol. 2001;116(6):940–946.
   PubMed Web of Science ®Google Scholar