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Articles

Comparing efficacy and safety of potassium hydroxide 5% solution with 5-fluorouracil cream in patients with actinic keratoses: a randomized controlled trial

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Pages 1376-1382 | Received 08 Jul 2020, Accepted 14 Aug 2020, Published online: 24 Sep 2020

References

  • Bobyr I, Campanati A, Consales V, et al. Ingenol mebutate in actinic keratosis: a clinical, videodermoscopic and immunohistochemical study. J Eur Acad Dermatol Venereol. 2017;31:260–266.
  • Costa C, Scalvenzi M, Ayala F, et al. How to treat actinic keratosis? An update. J Dermatol Case Rep. 2015;9:29–35.
  • Goldenberg G, Perl M. Actinic keratosis: update on field therapy. J Clin Aesthet Dermatol. 2014;7:28–31.
  • Longo C, Borsari S, Benati E, et al. Dermoscopy and reflectance confocal microscopy for monitoring the treatment of actinic keratosis with ingenol mebutate gel: report of two cases. Dermatol Ther (Heidelb). 2016;6:81–87.
  • Tarstedt M, Rosdahl I, Berne B, et al. A randomized multicenter study to compare two treatment regimens of topical methyl aminolevulinate (Metvix)-PDT in actinic keratosis of the face and scalp. Acta Derm Venereol. 2005;85:424–428.
  • Freeman RG, Knox JM, Heaton CL. The treatment of skin cancer. A statistical study of 1,341 skin tumors comparing results obtained with irradiation, surgery, and curettage followed by electrodesiccation. Cancer. 1964;17:535–538.
  • Mahmoudi H, Ghodsi SZ, Tavakolpour S, et al. Cryotherapy plus oral zinc sulfate versus cryotherapy plus placebo to treat common warts: A double blind, randomized, placebo-controlled trial. Int J Womens Dermatol. 2018;4:87–90.
  • Pampena R, Benati E, Borsari S, et al. Tracking actinic keratosis of face and scalp treated with 0.015% ingenol mebutate to identify clinical and dermoscopic predictors of treatment response. J Eur Acad Dermatol Venereol. 2018;32:1461–1468.
  • Szeimies RM, Karrer S, Radakovic-Fijan S, et al. Photodynamic therapy using topical methyl 5-aminolevulinate compared with cryotherapy for actinic keratosis: a prospective, randomized study. J Am Acad Dermatol. 2002;47:258–262.
  • Tavakolpour S, Daneshpazhooh M, Mahmoudi H. Skin cancer: genetics, immunology, treatments, and psychological care. In: Mehdipour P, editor. Cancer genetics and psychotherapy. Cham: Springer International Publishing; 2017. p. 851–934.
  • Thai KE, Fergin P, Freeman M, et al. A prospective study of the use of cryosurgery for the treatment of actinic keratoses. Int J Dermatol. 2004;43:687–692.
  • Heppt MV, Leiter U, Steeb T, et al. S3 guideline for actinic keratosis and cutaneous squamous cell carcinoma – short version, part 1: diagnosis, interventions for actinic keratoses, care structures and quality-of-care indicators. J Dtsch Dermatol Ges. 2020;18:275–294.
  • Siegel JA, Korgavkar K, Weinstock MA. Current perspective on actinic keratosis: a review. Br J Dermatol. 2017;177:350–358.
  • Kose O, Koc E, Erbil AH, et al. Comparison of the efficacy and tolerability of 3% diclofenac sodium gel and 5% imiquimod cream in the treatment of actinic keratosis. J Dermatolog Treat. 2008;19:159–163.
  • Philipp-Dormston WG, Battistella M, Boussemart L, et al. Patient-centered management of actinic keratosis. Results of a multi-center clinical consensus analyzing non-melanoma skin cancer patient profiles and field-treatment strategies. J Dermatolog Treat. 2020;31:576–582.
  • Asadi N, Hemmati E, Namazi G, et al. A comparative study of potassium hydroxide versus CO2 laser vaporization in the treatment of female genital warts: a controlled clinical trial. Int J Community Based Nurs Midwifery. 2016;4:274–282.
  • Chathra N, Sukumar D, Bhat RM, et al. A comparative study of 10% KOH solution and 5% imiquimod cream for the treatment of Molluscum contagiosum in the pediatric age group. Indian Dermatol Online J. 2015;6:75–80.
  • Hashmi F, Nester CJ, Wright CR, et al. The evaluation of three treatments for plantar callus: a three-armed randomised, comparative trial using biophysical outcome measures. Trials. 2016;17:251.
  • Huu SN, Quang MN, Van TN, et al. Efficacy of 10% potassium hydroxide solution versus 10% salicylic acid ointment in treatment of molluscum contagiosum – the low – cost dermatologic therapy in Vietnam. Open Access Maced J Med Sci. 2019;7:269–271.
  • Giner-Soriano M, Teixidó C, Marsal JR, et al.; the working group for the clinical trial IJG-KOH-2014. Randomized placebo-controlled clinical trial on efficacy and safety of topical 10% Potassium hydroxide for molluscum contagiosum treatment in children. J Dermatolog Treat. 2019;30:750–756.
  • Schmitz L, Gambichler T, Gupta G, et al. Actinic keratosis area and severity index (AKASI) is associated with the incidence of squamous cell carcinoma. J Eur Acad Dermatol Venereol. 2018;32:752–756.

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