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Journal of Dermatological Treatment Volume 33, 2022 - Issue 3
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Articles

Effects of TNF inhibitors and an IL12/23 inhibitor on changes in body weight and adipokine levels in psoriasis patients: a 48-week comparative study

Nahide Onsuna Dermatology Department School of Medicine, Bezmialem Vakif University, Istanbul, TurkeyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0001-6259-0219View further author information
ORCID Icon,
Tahsin Çağdaş Akaslana Dermatology Department School of Medicine, Bezmialem Vakif University, Istanbul, TurkeyORCID Iconhttps://orcid.org/0000-0002-7349-5783View further author information
ORCID Icon,
Kadriye Sallahoglua Dermatology Department School of Medicine, Bezmialem Vakif University, Istanbul, TurkeyView further author information
,
Aliye Sevdem Gülcana Dermatology Department School of Medicine, Bezmialem Vakif University, Istanbul, TurkeyView further author information
,
Huri Bulutb Medical Biochemistry Department School of Medicine, İstinye University, Istanbul, TurkeyView further author information
&
Ayşegül Yabacıa Dermatology Department School of Medicine, Bezmialem Vakif University, Istanbul, TurkeyView further author information
Pages 1727-1732 | Received 30 Jan 2021, Accepted 26 Feb 2021, Published online: 23 Mar 2022

References

  • Kanemaru K, Matsuyuki A, Nakamura Y, et al. Obesity exacerbates imiquimod-induced psoriasis-like epidermal hyperplasia and interleukin-17 and interleukin-22 production in mice. Exp Dermatol. 2015;24(6):436–442.
  • Mancuso P. The role of adipokines in chronic inflammation. Immunotargets Ther. 2016;5:47–56.
  • Shibata S, Saeki H, Tada Y, et al. Serum high molecular weight adiponectin levels are decreased in psoriasis patients. J Dermatol Sci. 2009;55(1):62–63.
  • Kyriakou A, Patsatsi A, Sotiriadis D, et al. Serum leptin, resistin, and adiponectin concentrations in psoriasis: a meta-analysis of observational studies. Dermatology. 2017;233(5):378–389.
  • de Souza Batista CM, Yang RZ, Lee MJ, et al. Omentin plasma levels and gene expression are decreased in obesity. Diabetes. 2007;56(6):1655–1661.
  • Fawcett RL, Waechter AS, Williams LB, et al. Tumor necrosis factor-alpha inhibits leptin production in subcutaneous and omental adipocytes from morbidly obese humans. J Clin Endocrinol Metab. 2000; 85(2):530–535.
  • Bruun JM, Pedersen SB, Kristensen K, et al. Effects of pro-inflammatory cytokines and chemokines on leptin production in human adipose tissue in vitro. Mol Cell Endocrinol. 2002;190(1-2):91–99.
  • Franchimont D, Roland S, Gustot T, et al. Impact of infliximab on serum leptin levels in patients with Crohn’s disease. J Clin Endocrinol Metab. 2005;90(6):3510–3516.
  • Ismail SA, Mohamed SA. Serum levels of visfatin and omentin-1 in patients with psoriasis and their relation to disease severity. Br J Dermatol. 2012;167(2):436–439.
  • Takahashi H, Tsuji H, Honma M, et al. Increased plasma resistin and decreased omentin levels in Japanese patients with psoriasis. Arch Dermatol Res. 2013;305(2):113–116.
  • Voloshyna I, Mounessa J, Carsons SE, et al. Effect of inhibition of interleukin-12/23 by ustekinumab on the expression of leptin and leptin receptor in human THP-1 macrophages. Clin Exp Dermatol. 2016;41(3):308–311.
  • Shibata S, Tada Y, Sy Hau C, et al. Adiponectin regulates psoriasiform skin inflammation by suppressing IL-17 production from γδ-T cells. Nat Commun. 2015;6:7687.

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