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Articles

Comorbidity identification and referral in atopic dermatitis: a consensus document

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Pages 2643-2653 | Received 17 Dec 2021, Accepted 13 Apr 2022, Published online: 28 Apr 2022

References

  • Weidinger S, Beck LA, Bieber T, et al. Atopic dermatitis. Nat Rev Dis Primers. 2018;4(1):1.
  • Hay RJ, Johns NE, Williams HC, et al. The global burden of skin disease in 2010: an analysis of the prevalence and impact of skin conditions. J Invest Dermatol. 2014;134(6):1527–1534.
  • Hua T, Silverberg JI. Atopic dermatitis in US adults: epidemiology, association with marital status, and atopy. Ann Allergy Asthma Immunol. 2018;121(5):622–624.
  • Chiesa Fuxench ZC, Block JK, Boguniewicz M, et al. Atopic dermatitis in America study: a cross-sectional study examining the prevalence and disease burden of atopic dermatitis in the US adult population. J Investig Dermatol. 2019;139(3):583–590. Mar
  • Silverberg JI, Gelfand JM, Margolis DJ, et al. Patient burden and quality of life in atopic dermatitis in US adults: a population-based cross-sectional study. Ann Allergy Asthma Immunol. 2018;121(3):340–347.
  • de Lusignan S, Alexander H, Broderick C, et al. The epidemiology of eczema in children and adults in England: a population-based study using primary care data. Clin Exp Allergy. 2021;51(3):471–482.
  • Yew YW, Thyssen JP, Silverberg JI. A systematic review and meta-analysis of the regional and age-related differences in atopic dermatitis clinical characteristics. J Am Acad Dermatol. 2019;80(2):390–401.
  • Wittkowski A, Richards HL, Griffiths CE, et al. The impact of psychological and clinical factors on quality of life in individuals with atopic dermatitis. J Psychosomat Res. 2004;57(2):195–200.
  • Poole CD, Chambers C, Allsopp R, et al. Quality of life and health-related utility analysis of adults with moderate and severe atopic dermatitis treated with tacrolimus ointment vs. topical corticosteroids. J Eur Acad Dermatol Venereol JEADV. 2009;24(6):674–678.
  • Ravnborg N, Ambikaibalan D, Agnihotri G, et al. Prevalence of asthma in patients with atopic dermatitis: a systematic review and meta-analysis. J Am Acad Dermatol. 2021;84(2):471-478.
  • Silverberg JI, Gelfand JM, Margolis DJ, et al. Association of atopic dermatitis with allergic, autoimmune, and cardiovascular comorbidities in US adults. Ann Allergy Asthma Immunol. 2018;121(5):604.e3–612.e3.
  • Suarez-Farinas M, Dhingra N, Gittler J, et al. Intrinsic atopic dermatitis shows similar TH2 and higher TH17 immune activation compared with extrinsic atopic dermatitis. J Allergy Clin Immunol. 2013;132(2):361–370.
  • Brunner PM, Silverberg JI, Guttman-Yassky E, et al. Increasing comorbidities suggest that atopic dermatitis is a systemic disorder. J Invest Dermatol. 2017;137(1):18–25.
  • Silverberg JI. Comorbidities and the impact of atopic dermatitis. Ann Allergy Asthma Immunol. 2019;123(2):144–151.
  • de Bruin-Weller M, Gadkari A, Auziere S, et al. The patient-reported disease burden in adults with atopic dermatitis: a cross-sectional study in Europe and Canada. J Eur Acad Dermatol Venereol. 2020;34(5):1026–1036.
  • Kauppi S, Jokelainen J, Timonen M, et al. Adult patients with atopic eczema have a high burden of psychiatric disease: a Finnish nationwide registry study. Acta Derm Venereol. 2019;99(7):647–651.
  • Bekić S, Martinek V, Talapko J, et al. Atopic dermatitis and comorbidity. Healthcare. 2020;8(2):70.
  • Sánchez J, Sánchez A, Cardona R. Particular characteristics of atopic eczema in tropical environments. The tropical environment control for chronic eczema and molecular assessment (TECCEMA) cohort study. An Bras Dermatol. 2017;92(2):177–183.
  • Schmitt J, Apfelbacher C, Chen CM, et al. Infant-onset eczema in relation to mental health problems at age 10 years: results from a prospective birth cohort study (German infant nutrition intervention plus). J Allergy Clin Immunol. 2010;125(2):404–410.
  • Arima K, Gupta S, Gadkari A, et al. Burden of atopic dermatitis in Japanese adults: analysis of data from the 2013 national health and wellness survey. J Dermatol. 2018;45(4):390–396.
  • Eckert L, Gupta S, Amand C, et al. Impact of atopic dermatitis on health-related quality of life and productivity in adults in the United States: an analysis using the national health and wellness survey. J Am Acad Dermatol. 2017;77(2):274–279.e3.
  • Kung J, Chiappelli F, Cajulis OO, et al. From systematic reviews to clinical recommendations for evidence-based health care: validation of revised assessment of multiple systematic reviews (R-AMSTAR) for grading of clinical relevance. Open Dent J. 2010;4:84–91.
  • Clark HD, Wells GA, Huet C, et al. Assessing the quality of randomized trials: reliability of the Jadad scale. Control Clin Trials. 1999;20(5):448–452.
  • Hoy D, Brooks P, Woolf A, et al. Assessing risk of bias in prevalence studies: modification of an existing tool and evidence of interrater agreement. J Clin Epidemiol. 2012;65(9):934–939.
  • Stang A. Critical evaluation of the Newcastle-Ottawa scale for the assessment of the quality of nonrandomized studies in meta-analyses. Eur J Epidemiol. 2010;25(9):603–605.
  • Whiting PF, Rutjes AW, Westwood ME, et al. QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med. 2011;155(8):529–536.
  • (CEBM) OUCfE-BM. CEBM levels of evidence 2011; [cited 2020 Sept 29]. Available from: https://www.cebm.net/
  • Schneider L, Hanifin J, Boguniewicz M, et al. Study of the atopic march: development of atopic comorbidities. Pediatr Dermatol. 2016;33(4):388–398.
  • Chello C, Carnicelli G, Sernicola A, et al. Atopic dermatitis in the elderly Caucasian population: diagnostic clinical criteria and review of the literature. Int J Dermatol. 2020;59(6):716–721.
  • Boguniewicz M-O, Bansal A. Efficacy of dupilumab in adolescents with moderate-to-severe atopic dermatitis with and without comorbid asthma: subgroup analysis from a 16-week randomized phase 3 trial. Allergy Eur J Allergy Clin Immunol. 2019;74:582–583.
  • Misery L, Ansolabehere X, Grandfils N, et al. Nine-year follow-up of children with atopic dermatitis by general practitioners [article]. Dermatology. 2014;228(4):344–349.
  • Raffi J, Suresh R, Botto N, et al. The impact of dupilumab on patch testing and the prevalence of comorbid allergic contact dermatitis in recalcitrant atopic dermatitis: a retrospective chart review. J Am Acad Dermatol. 2020;82(1):132–138.
  • Pols DHJ, Bohnen AM, Nielen MMJ, et al. Risks for comorbidity in children with atopic disorders: an observational study in Dutch general practices. BMJ Open. 2017;7(11):e018091.
  • Augustin M, Radtke MA, Glaeske G, et al. Epidemiology and comorbidity in children with psoriasis and atopic eczema. Dermatology. 2015;231(1):35–40.
  • Langan SM, Abuabara K, Henrickson SE, et al. Increased risk of cutaneous and systemic infections in atopic dermatitis-a cohort study. J Invest Dermatol. 2017;137(6):1375–1377.
  • Silverberg JI, Silverberg NB. Childhood atopic dermatitis and warts are associated with increased risk of infection: a US population-based study. J Allergy Clin Immunol. 2014;133(4):1041–1047.
  • Chaptini C, Quinn S, Marshman G. Methicillin-resistant Staphylococcus aureus in children with atopic dermatitis from 1999 to 2014: a longitudinal study. Australas J Dermatol. 2016;57(2):122–127.
  • Herrera I, Gascon F. [New tools in healthcare]. Med Clin. 2012;139(8):364–368.
  • Silverberg JI, Simpson EL. Association between severe eczema in children and multiple comorbid conditions and increased healthcare utilization. Pediatr Allergy Immunol. 2013;24(5):476–486.
  • Patel KR, Immaneni S, Singam V, et al. Association between atopic dermatitis, depression, and suicidal ideation: a systematic review and meta-analysis. J Am Acad Dermatol. 2019;80(2):402–410.
  • Kage P, Simon JC, Treudler R. Atopic dermatitis and psychosocial comorbidities. J Dtsch Dermatol Ges. 2020;18(2):93–102.
  • Laughter MR, Maymone MBC, Mashayekhi S, et al. The global burden of atopic dermatitis: lessons from the global burden of disease study 1990-2017. Br J Dermatol. 2021;184(2):304–309.
  • Holm JG, Agner T, Clausen ML, et al. Determinants of disease severity among patients with atopic dermatitis: association with components of the atopic march. Arch Dermatol Res. 2019;311(3):173–182.
  • Rønnstad ATM, Halling-Overgaard AS, Hamann CR, et al. Association of atopic dermatitis with depression, anxiety, and suicidal ideation in children and adults: a systematic review and meta-analysis. J Am Acad Dermatol. 2018;79(3):448.e30–456.e30.
  • Ahn HJ, Shin MK, Seo JK, et al. Cross-sectional study of psychiatric comorbidities in patients with atopic dermatitis and nonatopic eczema, urticaria, and psoriasis [article]. NDT. 2019;15:1469–1478.
  • Al-Naqeeb J, Danner S, Fagnan LJ, et al. The burden of childhood atopic dermatitis in the primary care setting: a report from the meta-LARC consortium. J Am Board Fam Med. 2019;32(2):191–200.
  • Choi M, Byun SJ, Lee DH, et al. The association with rhegmatogenous retinal detachment and paediatric atopic dermatitis: a 12-year nationwide cohort study. Eye. 2020;34(10):1909–1915.
  • Ramirez FD, Chen S, Langan SM, et al. Association of atopic dermatitis with sleep quality in children. JAMA Pediatr. 2019;173(5):e190025.
  • Hong S, Son DK, Lim WR, et al. The prevalence of atopic dermatitis, asthma, and allergic rhinitis and the comorbidity of allergic diseases in children. Environ Health Toxicol. 2012;27:e2012006.
  • Sybilski AJ, Raciborski F, Lipiec A, et al. Atopic dermatitis is a serious health problem in Poland. Epidemiology studies based on the ECAP study [article]. Postepy Dermatol Alergol. 2015;32(1):1–10.
  • Gough H, Grabenhenrich L, Reich A, MAS study group, et al. Allergic multimorbidity of asthma, rhinitis and eczema over 20 years in the German birth cohort MAS. Pediatr Allergy Immunol. 2015;26(5):431–437.
  • Röckmann H, Geel MJ, Knulst AC, et al. Food allergen sensitization pattern in adults in relation to severity of atopic dermatitis [article]. Clin Transl Allergy. 2014;4(1):9.
  • Chu H, Shin JU, Park CO, et al. Clinical diversity of atopic dermatitis: a review of 5,000 patients at a single institute [article]. Allergy Asthma Immunol Res. 2017;9(2):158–168.
  • Beck KM, Seitzman GD, Yang EJ, et al. Ocular co-morbidities of atopic dermatitis. Part I: associated ocular diseases. Am J Clin Dermatol. 2019;20(6):797–805.
  • Radtke MA, Schäfer I, Glaeske G, et al. Prevalence and comorbidities in adults with psoriasis compared to atopic eczema. J Eur Acad Dermatol Venereol. 2017;31(1):151–157.
  • Liao TC, Lien YT, Wang S, et al. Comorbidity of atopic disorders with autism spectrum disorder and attention deficit/hyperactivity disorder. J Pediatr. 2016;171:248–255.
  • de Wit J, Brada RJK, van Veldhuizen J, et al. Skin disorders are prominent features in primary immunodeficiency diseases: a systematic overview of current data. Allergy. 2019;74(3):464–482.
  • George SM, Karanovic S, Harrison DA, et al. Interventions to reduce Staphylococcus aureus in the management of eczema. Cochrane Database Syst Rev. 2019;2019(10):CD003871.
  • Sicras-Mainar A, Navarro-Artieda R, Armario-Hita JC. Severe atopic dermatitis in Spain: a real-life observational study [article]. TCRM. 2019;15:1393–1401.
  • Legendre L, Barnetche T, Mazereeuw-Hautier J, et al. Risk of lymphoma in patients with atopic dermatitis and the role of topical treatment: a systematic review and meta-analysis. J Am Acad Dermatol. 2015;72(6):992–1002.
  • Wu CY, Lu YY, Lu CC, et al. Osteoporosis in adult patients with atopic dermatitis: a nationwide population-based study. PLoS One. 2017;12(2):e0171667.
  • Paller AS, Spergel JM, Mina-Osorio P, et al. The atopic march and atopic multimorbidity: many trajectories, many pathways. J Allergy Clin Immunol. 2019;143(1):46–55.
  • Oliveira C, Torres T. More than skin deep: the systemic nature of atopic dermatitis. Eur J Dermatol. 2019;29(3):250–258.
  • Ravn NH, Ahmadzay ZF, Christensen TA, et al. Bidirectional association between atopic dermatitis, conjunctivitis, and other ocular surface diseases: a systematic review and meta-analysis. J Am Acad Dermatol. 2021;85(2):453–461.
  • Yang L, Fu J, Zhou Y. Research progress in atopic march. Front Immunol. 2020;11:1907.

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