379
Views
74
CrossRef citations to date
0
Altmetric
Research Article

Comparison of biological effects of DNA damage induced by ionizing radiation and hydrogen peroxide in CHO cells

Pages 67-75 | Published online: 03 Jul 2009

  • AHNSTRÖHM, G. and EDVARDSON, K. A., 1974, Radiation-induced single-strand breaks in DNA determined by rate of alkaline strand separation and hydroxylapatite chromatography: an alternative to velocity sedimentation. International Journal of Radiation Biology, 26, 493-497.
  • ALLAN, I. M., VAUGHAN, A. T. M., MILNER, A. E., LUNEC, J. and BACON, P. A., 1988, Structural damage to lymphocyte nuclei by H2O2 or gamma irradiation is dependent on the mechanism of OH radical production. British Journal of Cancer, 58, 34-37.
  • BLÖCHER, D., 1990, In CHEF electrophoresis a linear induction of dsb corresponds to a nonlinear fraction of extracted DNA with dose. International Journal of Radiation Biology, 57, 7-12.
  • BOVERIS, A. and CHANCE, B., 1973, The mitochondrial generation of hydrogen peroxide. General properties and effects of hyperbaric oxygen. Biochemical Journal, 134, 707-716.
  • Box, H. C., FREUND, H. G., BUDZINSKI, E. E., WALLACE, J. C. and MACCUBBIN, A. E., 1995, Free radical-induced double base lesions. Radiation Research, 141, 91-94.
  • BRADLEY, M. O. and ERICKSON, L. C., 1981, Comparison of the effects of hydrogen peroxide and X-ray irradiation on toxicity, mutation, and DNA damage/repair in mammalian cells (V-79). Biochimica et Biophysica Acta, 654, 135-141.
  • BRADLEY, M. O. and KOHN, K. W., 1979, X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution. Nucleic Acids Research, 7, 793-804.
  • CAI, L., KOROPATNICK, J. and CHERIAN, M. G., 1995, Metallothionein protects DNA from copper-induced but not iron-induced cleavage in vitro. Chemico-Biological Interactions, 96, 143-155.
  • CANTONI, O., MURRAY, D. and MEYN, R. E., 1986, Effect of 3-aminobenzamide on DNA strand-break rejoining and cytoxicity in CHO cells treated with hydrogen peroxide. Biochimica et Biophysica Ada, 867, 135-143.
  • CHAKRABARTI, S., KASSIS, A. I., SLAYTERS, H. S., BUMP, E. A., SAHU, S. K. and MAKRIGIORGOS, G. M., 1998, Continuous detection of radiation or metal generated hydroxyl radicals within core chromatin particles. International Journal of Radiation Biology, 73, 53-63.
  • CHIU, S. M., XUE, L.-Y., FRIEDMAN, L. R. and OLEINICK, N. L., 1995, Differential dependence on chromatin structure for copper and iron ion induction of DNA double-strand breaks. Biochemistry, 34, 2653-2661.
  • COLLINS, A. R., AI-GUO, M. and DUTHIE, S. J., 1995, The kinetics of repair of oxidative DNA damage (strand breaks and oxidised pyrimidines) in human cells. Mutation Research, 336, 69-77.
  • COSTA, N. D. and BRYANT, P. E., 1988, Repair of DNA single-strand and double-strand breaks in the Chinese hamster xrs5 mutant cell line as determined by DNA unwinding. Mutation Research, 194, 93-99.
  • DAHM-DAPHI, J. and DIKOMEY, E., 1996, Rejoining of DNA double-strand breaks in X-irradiated CHO cells studied by constant- and graded-field gel electrophoresis. International Journal of Radiation Biology, 69, 615-621.
  • DAHM-DAPHI, J., DIKOMEY, E., PYTTLIK, C. and JEGGO, P., 1993, Reparable and non-reparable DNA strand breaks induced by X-irradiation in CHO Kl cells and the radiosensitive mutants xrs1 and xrs5. International Journal of Radiation Biology, 64, 19-26.
  • DARROUDI, F., NATARAJAN, A. T., DER SCHANS, G. P. V. and VAN LOON, A. A. W. M., 1990, Biochemical and cytogenetical characterization of Chinese hamster ovary X-ray-sensitive mutant cells xrs5 and xrs6. V. The correlation of DNA strand breaks and base damage to chromosomal aberrations and sister-chromatid exchanges induced by X-irradiation. Mutation Research, 235, 119-127.
  • DEMPLE, B. and LINN, S., 1982, 5,6-Saturated thymine lesions in DNA: production by UV-light and hydrogen peroxide. Micleic Acids Research, 10, 3781-3789.
  • DHKWEL, P. A. and WENINK, P. W., 1986, Structural integrity of the nuclear matrix: Differential effects of thiol agents and metal chelators. Journal of Cell Science, 84, 53-67.
  • DIKOMEY, E. and FRANZKE, J., 1986, Three classes of DNA strand breaks induced by X-irradiation and internal ß-rays. International Journal of Radiation Biology, 50, 893-908.
  • DUELL, T., LENGFELDER, E., FINK, R., GIESEN, R. and BAUCHINGER, M., 1995, Effect of activated oxygen species in human lymphocytes. Mutation Research, 336, 29-38.
  • EPE, B., 1995, DNA damage profiles induced by oxidizing agents. Review of Physiology Biochemical Pharmacology, 127, 223-249.
  • FLENTJE, M., ASADPOUR, B, LATZ, D. and WEBER, K.J., 1993, Sensitivity of neutral filter elution but not PFGE can be modified by non-dsb chromatin damage. International Journal of Radiation Biology, 63, 715-724.
  • FÖHE, C. and DIKOMEY, E., 1994, Induction and repair of X-ray-induced DNA base damage studied in CHO cells using the M. luteus extract. International Journal of Radiation Biology, 66, 697-704.
  • FRAGA, C. G., SHIGENAGA, M. K., PARK, J.-W., DEGAN, P. and AMES, B. N., 1990, Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine. Proceedings of the National Academy of Sciences, USA, 87, 4533-4537.
  • GASSER, S. M., LAROCHE, T., FALQUET, J., BOY DE LA TOUR, E. and LAEMMLI, U. K., 1986, Metaphase chromosome structure. Involvement of topoisomerase II. Journal of Molecular Biology, 188, 613-629.
  • HALLIWELL, B. and GUTTERIDGE, J. M. C., 1990, Role of free radicals and catalytic metal ions in human disease: an overview. Methods in Ewymology, 186, 1-85.
  • HELD, K. D., SYLVESTER, F. C., HOPCIA, K. L. and BIAGLOW, J. E., 1996, Role of Fenton chemistry in thiolinduced toxicity and apoptosis. Radiation Research, 145, 542-553.
  • HENNER, W. D., RODRIGUEZ, L. O., HECHT, S. M. and HESELTINE, W. A., 1983, ?-Ray induced deoxyribonucleic acid strand breaks. Journal of Biological Chemistry, 258, 711-713.
  • HOLMES, G. E., BERNSTEIN, C. and BERNSTEIN, H., 1992, Oxidative and other DNA damages as the basis of aging: a review. Mutation Research, 275, 305-315.
  • ILIAKIS, G. E., PANTELIAS, G. B., OKAYASU, R. and BRADLEY, W. F., 1992, Induction by H2O2 of DNA and interphase chromosome damage in plateau-phase Chinese hamster ovary cells. Radiation Research, 131, 192-203.
  • JACKSON, S. P. and JEGGO, P. A., 1995, DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK. Trends in Biochemical Sciences, 20, 412-415.
  • JEGGO, P. A., 1990, Studies on mammalian mutants defective in rejoining double-strand breaks in DNA. Mutation Research, 239, 1-16.
  • JOHNSON, T. M., YU, Z.-X., FERRANS, V. J., LOWENSTEIN, R. A. and FINKEL, T., 1996, Reactive oxygen species are downstream mediators of p53-dependent apoptosis. Medical Science, 93, 11848-11852.
  • KEMP, L. M., SEDGWICK, S. G. and JEGGO, P. A., 1984, X-ray sensitive mutants of Chinese hamster ovary cells defective in double-strand break rejoining. Mutation Research, 132, 189-196.
  • KROEMER, G., ZAMZAMI, N. and SUSIN, S. A., 1997, Mitochondria! control of apoptosis. Immunology, 18, 44-51.
  • LE, X. C., XING, J. Z., LEE, J., LEADON, S. A. and WEINFELD, M., 1998, Inducible repair of thymine glycol detected by an ultrasensitive assay for DNA damage. Science, 280, 1066-1069.
  • LEWIS, C. D. A. and LAEMMLI, U. K., 1982, Higher order metaphase chromosome structure: evidence for metalloprotein interactions. Cell, 29, 171-181.
  • LIUNGMAN, M., 1991, The influence of chromatin structure on the frequency of radiation-induced DNA strand breaks: a study using nuclear and nucleoid monolayers. Radiation Research, 126, 58-64.
  • LJUNGMAN, M. and HANAWALT, P. C., 1992, Efficient protection against oxidative DNA damage in chromatin. Molecular Carcinogenesis, 5, 264-269.
  • LJUNGMAN, M., NYBERG, S., NYGREN, J., ERIKSSON, M. and AHNSTRÖHM, G., 1991, DNA-bound proteins contribute much more than soluble intracellular compounds to the intrinsic protection against radiation-induced DNA strand breaks in human cells. Radiation Research, 127, 171-176.
  • MELLO FILHO, A. and MENEGHINI, R., 1984, In vino formation of single-strand breaks in DNA by hydrogen peroxide is mediated by the Haber-Weiss reaction. Biochimica et Biophysica Acta, 781, 56-63.
  • NARAYANAN, P. K., GOODWIN, E. H. and LEHNERT, B. E., 1997, a-Particles initiate biological production of Superoxide anions and hydrogen peroxidevin human cells. Cancer Research, 57, 3963-3971.
  • NELSON, S. J., 1982, Models for DNA damage formation and repair in mammalian cells exposed to ionizing radiation. Radiation Research, 92, 120-145.
  • OIKAWA, S. and KAWANISHI, S., 1996, Site-specific DNA damage induced by NADH in the presence of copper (II): role of active oxygen species. Biochemistry, 35, 4584-4590.
  • OLEINICK, N. L., BALASUBRAMANIAM, U., XUE, L. and CHIU, S., 1994, Nuclear structure and the microdistribution of radiation damage in DNA. International Journal of Radiation Biology, 66, 523-529.
  • POLYAK, K., XIA, Y., ZWEIER, J. L., KINZLER, K. W. and VOGELSTEIN, B., 1997, A model for p53-induced apoptosis. Nature, 389, 300-305.
  • PRISE, K. M., DAVIES, S. and MICHAEL, B. D., 1989, Cell killing and DNA damage in Chinese hamster V79 cells treated with hydrogen peroxide. International Journal of Radiation Biology, 55, 583-592.
  • PRISE, K. M., HORNER, K. A. and McNALLY, N.J., 1992, Interaction of hydrogen peroxide and ionizing-radiation induced damage. British Journal of Radiology, 24 (suppl.), 28-31.
  • RODRIGUEZ, H., DROUIN, R., HOLMQUIST, G. P., O'CONNOR, T. R., BOITEUX, S., LAVAL, J., DOROSHOW, J. H. and AKMAN, S. A., 1995, Mapping of copper/hydrogen peroxide-induced DNA damage at nucleotide resolution in human genomic DNA by ligation-mediated poymerase chain reaction. Journal of Biological Chemistry, 270, 17633-17640.
  • RODRIGUEZ, H., HOLMQUIST, G. P., D'AGOSTINO, R., KELLER, J. and AKMAN, S. A., 1997, Metal ion-dependent hydrogen peroxide-induced DNA damage is more sequence specific than metal specific. Cancer Research, 57, 2394-2403.
  • ROOTS, R., HOLLEY, W., CHATTERJEE, A., IRIZARRY, M. and KRAFT, G., 1990, The formation of strand breaks in DNA after high-LET irradiation: a comparison of data from in vitro and cellular systems. International Journal of Radiation Biology, 58, 55-69.
  • RUEFF, J., BRAS, A., CRITOVAO, L., MEXIA, J., SA DA COSTA, M. and PIRES, V., 1993, DNA strand breaks and chromosomal aberrations induced by H2O2 and Co-gamma-radiation. Mutation Research, 289, 197-204.
  • Russo, T., ZAMBRANO, N., ESFOSITO, F., CIMINO, A. F., FISCELLA, M., JACKMAN, J., O'CONNOR, P. M., ANDERSON, C. W. and APPELLA, E., 1995, A p53-independent pathway for activation of WAFl/CIPl expression following oxidative stress. Journal of Biological Chemistry, 270, 29386-29391.
  • SARKER, A. H., WATANABE, S., SEKI, S., AKIYAMA, T. and OKADA, S., 1995, Oxygen radical-induced single-strand DNA breaks and repair of the damage in a cell-free system. Mutation Research, 337, 85-95.
  • SHENG-TANNER, X., BUMP, E. A. and HEDLEY, D. W., 1999, An oxidative stress-mediated death pathway in irradiated human leukemia cells mapped using multilaser flow cytometry. Radiation Research, 150, 636-647.
  • SIDDIQI, M. A. and BOTHE, E., 1987, Single- and double-strand break formation in DNA irradiated in aqueous solution: dependence on dose and OH radical scavenger concentration. Radiation Research, 112, 449-463.
  • TACCIOLI, G. E., GOTTLIEB, T. M., BLUNT, T., PRIESTLEY, A., DEMENGEOT, J., MIZUTA, R., LEHMANN, A. R., ALT, F. W., JACKSON, S. P. and JEGGO, P. A., 1994, Ku80: product of the XCRR5 gene and its role in DNA repair and V(D)J recombination. Science, 265, 1442-1445.
  • TEEBOR, G. W., BOORSTEIN, R. J. and CADET, J., 1988, The reparability of oxidative free radical mediated damage to DNA: a review. International Journal of Radiation Biology, 54, 131-150.
  • TOYOKUNI, S. and SAGRIPANTI, J.-L., 1992, Iron-mediated DNA damage: sensitive detection of DNA strand breakage catalyzed by iron. Journal of Inorganic Biochemistry, 47, 241-248.
  • VASSETZKY, Y. S., DAMG, Q., BENEDETTI, P. and GASSER, S. M., 1994, Topoisomerase II forms multimers in vitro: effects of metals, b-glycerophosphate, and phosphorylation of its C-terminal domain. Molecular and Cellular Biology, 14, 6962-6974.
  • VAUGHAN, A. T. M. and GORDON, D. J., 1992, Hydrogen peroxide lethality is associated with a decreased ability to maintain positive DNA supercoiling. Experimental Cell Research, 202, 376-380.
  • WALLACE, S.S., 1998, Enzymatic processing of radiation-induced free radical damage in DNA. Radiation Research, 150, S60-79.
  • WARD, J. F., 1985, Biochemistry of DNA lesions. Radiation Research, 104, 103-111.
  • WARD, J. F., BLAKELY, W. F. and JONER E. J., 1985, Mammalian cells are not killed by DNA single-strand breaks caused by hydroxyl radicals from hydrogen peroxide. Radiation Research, 103, 383-392.
  • WARD, J. F., EVANS, J. W., LIMOLI, C. L. and CALABRO-JONES, P. M., 1987, Radiation and hydrogen peroxide induced free radical damage to DNA. British Journal of Cancer, 55, Suppl. VIII, 105-112.
  • WARDMAN, P. and CANDEIAS, L. P., 1996, Fenton chemistry: an introduction. Radiation Research, 145, 523-531.
  • WLODEK, D., BANATH, J. and OLIVE, P. L., 1992, Comparison between pulsed-field and constant-field gel electrophoresis for measurement of DNA double-strand breaks in irradiated Chinese hamster ovary cells. International Journal of Radiation Biology, 60, 779-790.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.