Advanced search
Publication Cover
International Journal of Radiation Biology Volume 76, 2000 - Issue 1
Submit an article Journal homepage
15
Views
9
CrossRef citations to date
0
Altmetric
Research Article

Efficacy of 3,4,3-LIHOPO for reducing neptunium retention in the rat after simulated wound contamination

F. Paquet, B. Montegue, E. Ansoborlo, M. H. Henge-Napoli, P. Houpert, P. W. Durbin, K. N. Raymond Chemical Science Division, Ernest Orlando Lawrence Berkeley National Laboratory and Department of Chemistry, University of California, Berkeley, CA 94720, USA.
Pages 113-117 | Published online: 03 Jul 2009

  • DURBIN, P. W., JEUNG, N., RODGERS, S. J., TUROWSKI, P. N., WEITL, F. L., WHITE, D. L. and RAYMOND, K. N., 1989, Removal of 238Pu(IV) from mice by polycatecholate, -hydroxamate or -hydroxypyridonate ligands. Radiation Protection Doametiy, 26, 351-358.
  • DURBIN, P. W., KULLGREN, B, XU, J. and RAYMOND, K. N., 1997, New agents for in vivo chelation of uranium(VI): efficacy and toxicity in mice of multidentate catecholate and hydroxypyridonate ligands. Health Physics, 72, 865-879.
  • DURBIN, P. W., KULLGREN, B, XU, J, RAYMOND, K. N, ALLEN, P. G., BUCHER, J. J., EDELSTEIN, N. M. and SHUH, D. K., 1998, 237Np: oxidation state in vivo and chelation by multidentate catecholate and hydroxypiridonate ligands. Health Physics, 75, 34-50.
  • FISHER, R. A., 1954, Statistical Methods for Reseach Workers, 12th edition (New York: Hafner).
  • FRITSCH, P., HERBRETEAU, D., MOUTAIROU, K., LANTENOIS, G., RICHARD-LENAOUR, H., GRILLON, G., HOFFSCHIR, D., PONCY, J. L., LAURENT, A. and MASSE, R., 1994, Comparative toxicity of 3,4,3-LiHOPO and DTPA in baboons. Radiation Protection Dosimetry, 53, 315-318.
  • HENGÉ-NAPOLI, M. H., ARCHIMBAUD, M., ANSOBORLO, E., METIVIER, H. and GOURMELON, P., 1995, Efficacy of 3,4,3-LIHOPO for reducing the retention of uranium in rat after acute administration. International Journal of Radiation Biology, 68, 389-393.
  • ICRP, 1986, The Metabolism of Plutonium and Related Elements. ICRP Publication 48 (Oxford: Pergamon).
  • MORIN, M., NENOT, J. C. and LAFUMA, J., 1973, The behavior Of 237Np in the rat. Health Physics, 24, 311-315.
  • PAQUET, F, MÉTIVIER, H, PONCY, J. L., BURGADA, R. and BAILLY, T., 1997, Evaluation of the efficiency of DTPA and other new chelating agents for removing neptunium from target organs. International Journal of Radiation Biology, 71,613-621.
  • PAQUET, F., PONCY, J. L., MÉTIVIER, H., GRILLON, G., FRITSCH, P., BURGADA, R, BAILLY, T., RAYMOND, K. N. and DURBIN, P. W., 1995, Efficacy of 3,4,3-LIHOPO for enhancing the excretion of plutonium from rat after simulated wound contamination as a tributyl-n-phosphate complex. International Journal of Radiation Biology, 68, 663-668.
  • PAQUET, F., PONCY, J. L., RATEAU, G., BURGADA, R., BAILLY, T., LEROUX, Y., RAYMOND, K. N., DURBIN, P. W. and MASSE, R., 1994, Reduction of the retention of 238Pu inhaled as the tributylphosphate complex in rats treated by 3,4,3-LIHOPO. Radiation Protection Dosimety, 53, 323-326.
  • PAQUET, F, RAMOUNET, B, HENGÉ-NAPOLI, M. H, MÉTIVIER, H. and GOURMELON, P., 1998, In vitro experiments to determine the mechanisms by which chelators remove the actinides neptunium and uranium from the body. Radiation Protection Dosimetry, 79, 467-470.
  • STRADLING, G. N., 1994, Recent progress in decorporation of plutonium, americium and thorium. Radiation Protection Dosmuty, 53, 297-304.
  • STRADLING, G. N., GRAY, S. A., ELLENDER, M., MOODY, J. C., HODGSON, A., PEARCE, M. J., WILSON, I., BURGADA, R., BAILLY, T., LEROUX, Y., RAYMOND, K. N. and DURBIN, P. W., 1992, The efficacies of 3,4,3-LIHOPO and DTPA for enhancing the excretion of plutonium and americium from the rat: comparison with other siderophore analogues. International Journal of Radiation Biology, 62, 487-497.
  • STRADLING, G. N, GRAY, S. A, MOODY, J. C, PEARCE, M. J, WILSON, I., BURGADA, R, LEROUX, Y, RAYMOND, K. N. and DURBIN, P. W., 1993, The efficacies of 3,4,3-LIHOPO and DTPA for enhancing the excretion of plutonium and americium from the rat after simulated wound contamination as nitrates. International Journal of Radiation Biology, 64, 134-140.
  • VOLF, V., BURGADA, R., RAYMOND, K. N. and DURBIN, P. W., 1996, Treatment with 3,4,3-LIHOPO of simulated wounds contaminated with plutonium and americium in rat. International Journal of Radiation Biology, 70, 109- 114.
  • WHITE, D. L., DURBIN, P. W., JEUNG, N. and RAYMOND, K. N., 1988, Specific sequestring agents for the actinides. 16. Synthesis and initial biological testing of polydentate oxohydroxypyridinecarboxylate ligands. Journal of Medicinal Chemistry, 31, 11-18.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.