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Research Article

High levels of chromosome aberrations correlate with impaired in vitro radiation-induced apoptosis and DNA repair in human B-chronic lymphocytic leukaemia cells

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Pages 671-679 | Published online: 03 Jul 2009

  • ACHKAR, A. L., SABATIER, L. and DUTRILLAUX, B., 1988, Transmission of radiation-induced rearrangements through cell divisions. Mutation Research, 198, 191-198.
  • ALAPETITE, C., THIRION, P., DE LA ROCHEFORDIERE, A., COSSET, J. M., and MOUSTACCHI, E., 1999, Analysis by alkaline comet assay of cancer patients with severe reactions to radiotherapy: defective rejoining of radioinduced DNA strand breaks in lymphocytes of breast cancer patients. International Journal of Cancer, 83, 83-90.
  • BEGLEITER, A., LEE, K., ISRAELS, L. G., MOWAT, M. R. and JOHNSTON, J. B., 1994, Chlorambucil induced apoptosis in chronic lymphocytic leukemia (CLL) and its relationship to clinical efficacy. Leukemia, 8 (suppl. 1), S103-106.
  • BELLOSILLO, B., COLOMER, D., PONS, G. and GIL, J., 1998, Mitoxantrone, a topoisomerase II inhibitor, induces apoptosis of B-chronic lymphocytic leukaemia cells. British Journal of Haematology, 100, 142-146.
  • BULLRICH, F., RASIO, D., KITADA, S., STAROSTIK, P., KIPPS, T., KEATING, M., ALBITAR, M., REED, J. C. and CROCE, C. M., 1999, ATM mutations in B-cell chronic lymphocytic leukemia. Cancer Research, 59, 24-27.
  • CHESON, B. D., BENNETT, J. M., GREVER, M., KAY, N., KEATING, M. J., O'BRIEN, S. and RAI, K. R., 1996, National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Blood, 87, 4990-4997.
  • COMBY, E., ANDRE, I., TROUSSARD, X., LEBRUN, E., SOLA, B., BALLET, J. J. and LEPORRIER, M., 1999, In vitro evaluation of B-CLL cells apoptotic responses to irradiation. Leukemia and Lymphoma, 34, 159-166.
  • DELIC, J., MASDEHORS, P., OMURA, S., COSSET, J. M., DUMONT, J., BINET, J. L. and MAGDELENAT, H., 1998, The proteasome inhibitor lactacystin induces apoptosis and sensitizes chemo-and radioresistant human chronic lymphocytic leukaemia lymphocytes to TNF-alpha-initiated apoptosis [see comments]. British Journal of Cancer, 77, 1103-1107.
  • DELIC, J., MORANGE, M. and MAGDELENAT, H., 1993, Ubiquitin pathway involvement in human lymphocyte gammairradiation-induced apoptosis. Molecular and Cell Biology, 13, 4875-4883.
  • DIVE, C. and HICKMAN, J. A., 1991, Drug-target interactions: only the first step in the commitment to a programmed cell death? British Journal of Cancer, 64, 192-196.
  • EL ROUBY, S., THOMAS, A., COSTIN, D., ROSENBERG, C. R., POTMESIL, M., SILBER, R. and NEWCOMB, E. W., 1993, P53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression. Blood, 82, 3452-3459.
  • FLAMAN, J. M., FREBOURG, T., MOREAU, V., CHARBONNIER, F., MARTIN, C., CHAPPUIS, P., SAPPINO, A. P., LIMACHER, I. M., BRON, L., BENHATTAR, J., TADA, M., VAN MEIR, E. G., ESTREICHER, A. and IGGO, R. D. J., 1995, A simple p53 functional assay for screening cell lines, blood, and tumors. Proceedings of the National Academy of Sciences, USA, 92, 3963-3967.
  • HANADA, M., DELIA, D., AIELLO, A, STADTMAUER, E. and REED, J. C., 1993, Bcl-2 gene hypomethylation and highlevel expression in B-cell chronic lymphocytic leukemia. Blood, 82, 1820-1828.
  • LOUAGIE, H., PHILIPPE, J., VRAL, A, CORNELISSEN, M., THIERENS, H. and DE RIDDER, L., 1998, Induction of micronuclei and apoptosis in natural killer cells compared with T lymphocytes after gamma-irradiation. International Journal of Radiation Biology, 73, 179-185.
  • MASDEHORS, P., MERLE-BERAL, H., MALOUM, K., OMURA, S., MAGDELENAT, H. and DELIC, J., 2000, Deregulation of the ubiquitin system and P53 proteolysis modifies apoptotic response in B-cell lymphocytes. Blood, 96, 269-274.
  • MASDEHORS, P., OMURA, S., MERLE-BERAL, H., MENTZ, F., COSSET, J. M., DUMONT, J., MAGDELENAT, H. and DELIC, J., 1999, Increased sensitivity of CLL-derived lymphocytes to apoptotic death activation by the proteasome-specific inhibitor lactacystin. British Journal of Haematology, 105, 752-757.
  • MCCONKEY, D. J., AGUILAR-SANTELISES, M., HARTZELL, P., ERIKSSON, I., MELLSTEDT, H., ORRENIUS, S. and JONDAL, M., 1991, Induction of DNA fragmentation in chronic B-lymphocytic leukemia cells. Journal of Immunology, 146, 1072-1076.
  • MULLER, C., CHRISTODOULOPOULOS, G., SALLES, B. and PANASCI, L., 1998, DNA-dependent protein kinase activity correlates with clinical and in vitro sensitivity of chronic lymphocytic leukemia lymphocytes to nitrogen mustards. Blood, 92, 2213-2219.
  • MULLER, M. R., BUSCHFORT, C., THOMALE, J., LENSING, C., RAJEWSKY, M. F. and SEEBER, S., 1997, DNA repair and cellular resistance to alkylating agents in chronic lymphocytic leukemia. Clinical Cancer Research, 3, 2055-2061.
  • O'BRIEN, S., DEL GIGLIO, A. and KEATING, M., 1995, Advances in the biology and treatment of cell chronic lymphocytic leukemia. Blood, 85, 307-318.
  • OLIVE, P. L., 1998, The role of DNA single- and double-strand breaks in cell killing by ionizing radiation. Radiation Research, 150, S42-51.
  • OLIVIER, M., BAUTISTA, S., VALLES, H. and THEILLET, C., 1998, Relaxed cell-cycle arrests and propagation of unrepaired chromosomal damage in cancer cell lines with wild-type p53. Molecular Carcinogenesis, 23, 1-12.
  • REED, J. C., 1998, Molecular biology of chronic lymphocytic leukemia. Seminars in Oncology, 25, 11-18.
  • RIBALLO, E., CRITCHLOW, S. E., TEO, S. H., DOHERTY, A. J., PRIESTLEY, A., BROUGHTON, B., KYSELA, B., BEAMISH, H., PLOWMAN, N., ARLETT, C. F., LEHMANN, A. R., JACKSON, S. P. and JEGGO, P. A., 1999, Identification of a defect in DNA ligase IV in a radiosensitive leukaemia patient. Current Biology, 9, 699-702.
  • ROBERTSON, L. E. and PLUNKETT, W., 1993, Apoptotic cell death in chronic lymphocytic leukemia. Leukemia and Lymphama, 11, 71-74.
  • SCHWARTE J. L. and JORDAN, R., 1997, Selective elimination of human lymphoid cells with unstable chromosome aberrations by p53-dependent apoptosis. Carcinogenesis, 18, 201-205.
  • SEKI, H., IWAI, K., KANEGANE, H., KONNO, A., OHTA, K., YACHIE, A, TANIGUCHI, N. and MIYAWAKI, T., 1995, Differential protective action of cytokines on radiation-induced apoptosis of peripheral lymphocyte subpopulations. Cell Immunology, 163, 30-36.
  • STANKOVIC, T., WEBER, P., STEWART, G., BEDENHAM, T., MURRAY, J., BYRD, P. J., Moss, P. A AND TAYLOR, A. M., 1999, Inactivation of ataxia telangiectasia mutated gene in B-cell chronic lymphocytic leukaemia [see comments]. Lancet, 353, 26-29.
  • TAMAKI, T., YONEZAWA, T., KANAYAMA, Y., INDUE, R., KANAKURA, Y, KATAGIRI, S., MACHII, T., KITANI, T. and TARUI, S., 1985, Mitogenic response of neoplastic 'hairy cells' to Staphylococcus aureus Cowan I. Mppon Ketsueki Gakkai Zasshi, 48, 1042-1052.
  • THOMAS, A., EL ROUBY, S., REED, J. C., KRAJEWSKI, S., SILBER, R., POTMESIL, M. and NEWCOMB, E. W., 1996, Drug-induced apoptosis in B-cell chronic lymphocytic leukemia: relationship between p53 gene mutation and bcl-2/bax proteins in drug resistance. Oncogene, 12, 1055-1062.

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