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Research Article

Modification of ionizing radiation clustered damage: estimate of the migration distance of holes through DNA via guanyl radicals under physiological conditions

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Pages 733-741 | Published online: 03 Jul 2009

  • ANDERSON, R. F. and PATEL, K., 1991, Pulse radiolysis studies of electron migration in DNA from DNA base radical anions to nitroacridine intercalators in aqueous solutions. Journal of the Chemical Society Faraday Transactions, 87, 3739-3746.
  • BECKER, D. and SEVILLA, M. D., 1993, The chemical consequences of radiation damage to DNA. Advances in Radiation Biology, 17, 121-180.
  • BIXON, M., GIESE, B., WESSELY, S., LANGENBACHER, T., MICHEL-BEYERLE, M. E. and JORTNER, J., 1999, Long range charge hopping in DNA. Proceedings of the National Academy of Sciences, USA, 96, 11713-11716.
  • BONNER, J. A. and LAWRENCE, T. S., 1990, Doxorubicin decreases the repair of radiation induced DNA damage. International Journal of Radiation Biology, 57, 55-64.
  • CAI, Z., GU, Z. and SEVILLA, M. D., 2001, Electron spin resonance study of electron and hole transfer in DNA: effects of hydration, aliphatic amine cations, and histone proteins. Journal of Physical Chemistry B, 105, 6031-6041.
  • CHAIRES, J. B., SATYANARAYANA, S., SUH, D., FOKT, I., PRZEWOLKA, T. and PRIEBE, W., 1996, Parsing the free energy of anthracycline antibiotic binding to DNA. Biochemistry, 35, 2047-2053.
  • CHAPMAN, J. D., REUVERS, A. P., BORSA, J. and GREENSTOCK, C. L., 1973, Chemical radioprotection and radiosensitization of mammalian cells growing in vitro. Radiation Research, 56, 291-306.
  • CULLIS, P. M., JONES, G. D. D., SYMONS, M. C. R. and LEA, J. S., 1987, Electron transfer from protein to DNA in irradiated chromatin. Nature, 330, 773-774.
  • DAVID-CORDONNIER, M.-H., LAVAL, J. and O'NEILL, P., 2000, Clustered DNA damage, influence on damage excision by XRS5 nuclear extracts and Escherichia cou Nth and Fpg proteins. Journal of Biological Chemistry, 275, 11865-11873.
  • DEBIJE, M. G., MILANO, M. T. and BERNHARD, W. A., 1999, DNA responds to ionizing radiation as an insulator, not as a 'molecular wire'. Angewandte Chenue, International Edition in English, 38, 2752-2756.
  • DEBIJE, M. G., RAZSKAZDVSKIY, Y. and BERNHARD, W. A., 2001, The yield of strand breaks resulting from direct type effects in crystalline DNA X-irradiated at 4 K and room temperature. Journal of the American Chemical Society, 123, 2917-2918.
  • DIANOV, G. L., O'NEILL, P. and GOODHEAD, D. T., 2001, Securing genome stability by orchestrating DNA repair: removal of radiation-induced clustered lesions in DNA. Bioessays, 23, 745-749.
  • DOROSHOW, J. H., SYNOLD, T. W., SOMLO, G., AKMAN, S. A. and GAJEWSKI, E., 2001, Oxidative DNA base modifications in peripheral blood mononuclear cells of patients treated with high dose infusional doxorubuicin. Blood, 97, 2839-2845.
  • FRIEDLAND, W., JACOB, P., PARETZKE, H. G., MERZAGORA, M. and OTTOLENGHI, A., 1999, Simulation of DNA fragment distributions after irradiation with photons. Radiation and Environmental Biophysics, 38, 39-47.
  • FUCIARELLI, A. F., WEGHER, B. J., BLAKELY, W. F. and DIZDAROGLU, M., 1990, Yields of radiation induced base products in DNA: effects of DNA conformation and gassing conditions. International Journal of Radiation Biology, 58, 397-415.
  • GIESE, B., 2000, Long distance charge transport in DNA: the hopping mechanism. Accounts of Chemical Research, 33, 631-636.
  • GIESE, B., AMAUDRUT, J., KOHLER, A K., SPORMANN, M. and WESSELY, S., 2001, Direct observation of hole transfer through DNA by hopping between adenine bases and by tunneling. Nature, 412, 318-320.
  • GOODHEAD, D. T., 1994, Initial events in the cellular effects of ionizing radiations: clustered damage in DNA. International Journal of Radiation Biology, 65, 7-17.
  • HALL, D. B., HOIADLN, R. E. and BARTON, J. K., 1996, Oxidative DNA damage through long range electron transfer. Nature, 382, 731-735.
  • HARRISON, L., HATAHET, Z. and WALLACE, S. S., 1999, In vitro repair of synthetic ionizing radiation-induced multiply damaged DNA sites. Journal of Molecular Biology, 290, 667-684.
  • HENDERSON, P. T., JONES, D., HAMPIKIAN, G., KAN, Y. and SCHUSTER, G. B., 1999, Long distance charge transport in duplex DNA: the phonon assisted polaron like hopping mechanism. Proceedings of the National Academy of Sciences, USA, 96, 8353-8358.
  • HILDENBRAND, K. and SCHULTE-FROHLINDE, D., 1990, ESR spectra of radicals of single and double stranded DNA in aqueous solution. Implications for ?OH induced strand breakage. Free Radical Research Communications, 11, 195-206.
  • HOLLEY, W. R. and CHATTERJEE, A., 1996, Clusters of DNA induced by ionizing radiation: formation of short DNA fragments. I. Theoretical modeling. Radiation Research, 145, 188-199.
  • JOVANOVIC, S. V. and SIMIC, M. G., 1989, The DNA guanyl radical: kinetics and mechanisms of generation and repair. Biochimica et Biophysica Acta, 1008, 39-44.
  • LUTZE, L. H. and WINEGAR, R. A., 1990, pHAZE: a shuttle vector system for the detection and analysis of ionizing radiation induced mutations. Mutation Research, 245, 305-310.
  • MANIOTTO, P., SPERANZA, G. and MALATESTA, V., 1989, The quenching of 1O2 (1g) by anthracyclines in aqueous solution. Evidence for a charge transfer mechanism. Chemical Physics Letters, 159, 310-314.
  • MARTIN, R. F. and ANDERSON, R. F., 1998, Pulse radiolysis studies indicate that electron transfer is involved in radioprotection by Hoechst 33342 and methylproamine. International Journal of Radiation Oncology, Biology, Physics, 42, 827-831.
  • MELVIN, T., BOTCHWAY, S. W., PARKER, A. W. and O 'NEILL, P., 1996, Induction of strand breaks in single stranded polynucleotides and DNA by photosensitization: one electron oxidized nucleobase radicals as precursors. Journal of the American Chemical Society, 118, 10031-10036.
  • MILANO, M. T., HU, G. G., WILLIAMS, L. D. and BERNHARD, W. A., 1998, Migration of electrons and holes in crystalline d(CGATCG) anthracycline complexes X-irradiated at 4K. Radiation Research, 150, 101-114.
  • MILLIGAN, J. R., AGUILERA, J. A. and WARD, J. F., 1993, Variation of single strand break yield with scavenger concentration for plasmid DNA irradiated in aqueous solution. Radiation Research, 133, 151-157.
  • MILLIGAN, J. R., AGUILERA, J. A., MARES, E. J., PAGLINAWAN, R. A. and WARD, J. F., 2001a, Reaction of guanyl radicals in plasmid DNA with biological reductants. Chemical repair of DNA damage produced by the direct effect of ionizing radiation. International Journal of Radiation Biology, 77, 1095-1108.
  • MILUGAN, J. R., AGUILERA, J. A. and WARD, J. F., 2001b, Redox equilibrium between guanyl radicals and thiocyanate influences base damage yields in gamma irradiated plasmid DNA. Estimation of the reduction potential of guanyl radicals in plasmid DNA in aqueous solution at physiological ionic strength. International Journal of Radiation Biology, 77, 1195-1205.
  • NIKJOO, H., O'NEILL, P., WILSON, W. E. and GOODHEAD, D. T., 2001, Computational approach for determining the spectrum of DNA damage induced by ionizing radiation. Radiation Research, 156, 577-583.
  • O'NEILL, P., PARKER, A. W., PLUMB, M. A. and SIEBBELES, L. D. A., 2001, Guanine modifications following ionization of DNA occurs predominantly via intra and not interstrand charge migration: an experimental and theoretical study. Journal of Physical Chemistry B, 105, 5283-5290.
  • PAN, J., LIN, W., WANG, W., HAN, Z., LU, C., YAO, S., LIN, N. and ZHU, D., 2001, A kinetic study on the interaction of deprotonated purine radical cations with amino acids and model peptides. Biophysical Chemistry, 89, 193-199.
  • PEZESHK, A., SYMONS, M. C. R. and MCCLYMONT, J. D., 1996, Electron movement along DNA strands: use of intercalators and electron paramagnetic resonance spectroscopy. Journal of Physical Chemistry, 100, 18562-18566.
  • PRIYADARSHY, S., RISSER, S. M. and BERATAN, D. N., 1996, DNA is not a molecular wire: protein like electron transfer predicted for an extended p-electron system. Journal of Physical Chemistry, 100, 17678-17682.
  • ROOTS, R. and OKADA, S., 1975, Estimation of lifetimes and diffusion distances of radicals involved in X-ray induced strand breaks and killing of mammalian cells. Radiation Research, 64, 306-320.
  • SARTOR, V., BOONE, E. and SCHUSTER, G. B., 2001, Long distance radical cation migration through AT base pairs in DNA. An experimental test of theory. Journal of Physical Chemistry B, 105, 11057-11059.
  • SCHUSTER, G. B., 2000, Long range charge transfer in DNA: transient structural distortions control the distance dependence. Accounts of Chemical Research, 33, 253-260.
  • SHAFIROVICH, V., DOURANDIN, A., HUANG, W. and GEACINTOV, N. E., 2001, The carbonate radical is a site selective oxidizing agent of guanine in double stranded oligonucleotides. Journal of Biological Chemistry, 276, 24621-24626.
  • SPINKS, J. W. T. and WOODS, R. J., 1976, An Introduction to Radiation Chemistry, 2nd edn (New York: Wiley).
  • STANBURY, D. M., 1989, Reduction potentials involving inorganic free radicals in aqueous solution. Advances in Inorganic Chemistry, 33, 69-138.
  • STEENKEN, S. and JOVANOVIC, S. V., 1997, How easily oxidizable is DNA? One electron reduction potentials of adenosine and guanosine in aqueous solution. Journal of the American Chemical Society, 119, 617-618.
  • SWARTS, S. G., BECKER, D., SEVILLA, M. and WHEELER, K. T., 1996, Radiation induced DNA damage as a function of hydration. II. Base damage from electro loss centers. Radiation Research, 145, 304 314.
  • VON SONNTAG, C., 1987, The Chemical Basis of Radiation Biology (Philadelphia: Taylor & Francis).
  • WAGENKNECHT, H.-A., STEMP, E. D. A. and BARTON, J. K., 2000, DNA bound peptide radicals generated through DNA mediated electron transport. Biochemistry, 39, 5483-5491.
  • WARD, J. F., 1981, Some biochemical consequences of the spatial distribution of ionizing radiation produced free radicals. Radiation Research, 86, 183-195.
  • WARD, J. F., 1994, The complexity of DNA damage. Relevance to biological consequences. International Journal of Radiation Biology, 66, 427-432.
  • WARDMAN, P., 1989, Reduction potentials of one electron couples involving free radicals in aqueous solution. Journal of Physical and Chemical Reference Data, 18, 1637-1755.
  • WEINFELD, M., RASOULI-NIA, A., CHAUDHRY, M. A. and BRITTEN, R. A., 2001, Response of base excision repair enzymes to complex DNA lesions. Radiation Research, 156, 584-589.
  • YAMAZAKI, H., INDUE, T., TANAKA, E., YOSHIDA, K., IMAI, A., YOSHIOKA, Y., NAKAMURA, H. YOSHIDA, J. and INDUE, T., 2000, Radiation and low dose adriamycin for the treatment of carcinoma of the hypopharynx. Anticancer Research, 20, 4713-4720.
  • ZEMAN, S. M., PHILLIPS, D. R. and CROTHERS, D. M., 1998, Characterization of covalent adriamycin DNA adducts. Proceedings of the National Academy of Sciences, USA, 95, 11561-11565.
  • ZHARKOV, D. O., RIEGER, R. A., IDEN, C. R. and GROLLMAN, A. P., 1997, NH2 terminal proline acts as a nucleophile in the glycosylase/AP lyase reaction catalyzed by Escherichia coli formamidopyrimidine-DNA glycosylase (Fpg) protein. Journal of Biological Chemistry, 272, 5335-5341.

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