Identification of proteins in the hamster DNA end‐binding complex

References

• ARIUMI, Y., MASUTANI, M., COPELAND, T. D., M1MO1U, T., SUGLIVIURA, T., SHIMOTOHNO, K., UEDA, K., HATANAKA, M. and NODA, M., 1999, Suppression of the poly(ADP-ribose) polymerase activity by DNA-dependent protein kinase in vitro. Oncogene, 18, 4616–4625.
   Google Scholar
• BARNES, D. E., STAMP, G., ROSEWELL, I., DENZEL, A. and LINDAHL, T., 1998, Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice. Current Biology, 8, 1395–1398.
   PubMed Web of Science ®Google Scholar
• BLUN TT., F1NNIE, N. J., TACCIOLI, G. E., Smrru, G. C., DEMENGEO, T. J., GOTTLIEB, T. M., MIZUTA, R., VARGHESE, A. J., ALT, F. W., JEGGO, P. A. and JACKSON, S. P., 1995, Defective DNA-dependent protein kinase activity is linked to V(DJ recombination and DNA repair defects associated with the murine scid mutation. Cell, 80, 813–823.
   Google Scholar
• BURNS, J. L., GUZDER, S. N., SUNG, P., PRAKASH, S. and PRAKASH, L., 1996, An affinity of human replication protein A for ultraviolet-damaged DNA. Journal of Biological Chemistry, 271, 11607–11610.
   PubMed Web of Science ®Google Scholar
• CHEONG, N., PERRAULT, A. R., WANG, H., WACHSBERGER, P., MAmmEN, P., JACKSON, I. and Immu, G., 1999, DNA-PK-independent rejoining of DNA double-strand breaks in human cell extracts in vitro. International Journal of Radiation Biology, 75, 67–81.
   PubMed Web of Science ®Google Scholar
• CHERNIKOVA, S. B., WELLS, R. L. and ELK1ND, M. M., 1999, Wortmanin sensitizes mammalian cells to radiation by inhibiting the DNA-dependent protein kinase-mediated rejoining of double-strand breaks. Radiation Research, 151, 159–166.
   Google Scholar
• CONSTANT1NOU, A., TARSOUNAS, M., KAROW, J. K., BROSH, R. M., BOHR, V. A., HICKSON, I. D. and WEST, S. C., 2000, Werner's syndrome protein (VVRN) migrates Holliday junctions and co-localizes with RPA upon replication arrest. EMBO Reports, 1, 80–84.
   PubMed Web of Science ®Google Scholar
• CRITCHLOW, S. E., BOWATER, R. P. and JACKSON, S. P., 1997, Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV. Current Biology, 7, 588–598.
   PubMed Web of Science ®Google Scholar
• DIBIASE, S. J., ZENG, Z. C., CHEN, R., HYSLOP, T., CURRAN, W. J., JR and Iumus, G., 2000, DNA-dependent protein kinase stimulates an independently active, nonhomologous, end-joining apparatus. Cancer Research, 60, 1245–1253.
   PubMed Web of Science ®Google Scholar
• DOLGANOV, G. M., MASER, R. S., NOVIKOV, A., TOSTO, L., CHONG, S., BRESSAN, D. A. and PETR1NI, J. H., 1996, Human Rad50 is physically associated with human Mrell: identification of a conserved multiprotein complex implicated in recombinational DNA repair. Molecular and Cellular Biology, 16, 4832–4841.
   Google Scholar
• GALANDE, S. and KOHWI-SHIGEMATSU, T., 1999, Poly(ADP-ribose) polymerase and Ku autoantigen form a complex and synergistically bind to matrix attachment sequences. Journal of Biological Chemistry, 274, 20521–20528.
   Google Scholar
• GALANDE, S. and KOHWI-SHIGEMATSU, T., 2000, Caught in the act: binding of Ku and PARP to MARs reveals novel aspects of their functional interaction. Critical Reviews of Eukaryotic Gene Expression, 10, 63–72.
   Google Scholar
• GRAWUNDER, U., ZIMMER, D., KULESZA, P. and LIEBER, M. R., 1998, Requirement for an interaction of XRCC4 with DNA ligase IV for wild-type V(DJ recombination and DNA double-strand break repair in vivo. Journal of Biological Chemistry, 273, 24708–24714.
   PubMed Web of Science ®Google Scholar
• HABER, J. E., 2000, Partners and pathways repairing a double-strand break. Trends in Genetics, 16, 259–264.
   PubMed Web of Science ®Google Scholar
• HARTWELL, L. H. and KASTEN, M. B., 1994, Cell cycle control and cancer. Science, 266, 182–188.
   Web of Science ®Google Scholar
• HERCEG, Z. and WANG, Z. Q„ 2001, Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death. Mutation Research, 477, 97–110.
   Google Scholar
• HUANG, J. and DAN, W. S., 2002, Reconstitution of the mammalian DNA double-strand break end-joining reaction reveals a requirement for an Mre 11 /Rad50/ NBS1-containing fraction. Nucleic Acids Research, 30, 667-674. hums, G. and SEANER, R., 1999, A DNA double-strand break repair-deficient mutant of CHO cells shows reduced radiosensitization after exposure to hyperthermic tem-peratures in the plateau phase of growth. International Journal of Hyperthermia, 6, 801–812.
   Google Scholar
• KANNAR, R., HOEIJMAKERS, J. H. and VAN GENT, D. C., 1998, Molecular mechanisms of DNA double strand break repair. Trends in Cell Biology, 8, 483–489.
   PubMed Web of Science ®Google Scholar
• KARAN, P., 2000, DNA double strand break repair in mammalian cells. Current Opinion in Genetics and Development, 10, 144–150.
   PubMed Web of Science ®Google Scholar
• KHARBANDA, S., PANDEY, P., JE\r, S. F., INOUE, S., BHARTI, A., YUAN, Z. M., WEICHSELBAUM, R., WEAVER, D. and KIJFE, D., 1997, Functional interaction between DNA-PK and c-Abl in response to DNA damage. Nature, 386, 732–735.
   Google Scholar
• LEE, J.-H., GHIRLANDO, R., BHAsRARA, V., HOFFMEYER, M. R., Gu, J. and PAULL, T. T., 2003, Regulation of Mre 1 1/Rad50 by Nbsl: effects on nucleotide-dependent DNA binding and association with ATLD mutant complexes. Journal of Biological Chemistry, 278, 45171–45181.
   Google Scholar
• LIT, K. J., HUANG, J., TAKEDA, Y. and DYNAN, W. S., 2000, DNA ligase IV and XRCC4 form a stable mixed tetramer that functions synergistically with other repair factors in a cell-free end-joining system. Journal of Biological Chemistry, 275, 34787–34796.
   PubMed Web of Science ®Google Scholar
• LEE, S. E., MOORE, J. K., HoLmEs, A., UMEZU, K., KOLODNER, R. D. and HABER, J. E., 1998, Saccharomyces Ku70, Mre 11/ Rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell, 94, 399–409.
   PubMed Web of Science ®Google Scholar
• LI, B. and COMAI, L., 2000, Functional interaction between Ku and the Werner syndrome protein in DNA end processing. Journal of Biological Chemistry, 275, 28349–28352.
   PubMed Web of Science ®Google Scholar
• MARDER, B. A. and MORGAN, W. F., 1993, Delayed chromosomal instability by DNA damage. Molecular and Cellular Biology, 13, 6667–6677.
   PubMed Web of Science ®Google Scholar
• MASER, R. S., MONSEN, K. J., NELms, B. E. and PETRINI, J. H., 1997, hMRE1 1 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks. Molecular and Cellular Biology, 17, 6087–6096.
   PubMed Web of Science ®Google Scholar
• MORRISON, C., SMITH, G. C., STINGL, L., JACKSON, S. P., WAGNER, E. F. and WANG, Z. Q, 1997, Genetic interaction between PARP and DNA-PK in V(Dll recombination and tumorigenesis. Nature Genetics, 17, 479–482.
   PubMed Web of Science ®Google Scholar
• NICK-MCELHINNY, S. A., SNOWDEN, C. M., MCCARVILLE, J. and RAMSDEN, D. A., 2000, Ku recruits the XRCC4-ligase IV complex to DNA ends. Molecular and Cellular Biology, 20, 2996–3003.
   Google Scholar
• PAULL, T. T. and GELLERT, M., 1998, The 3' to 5' exonuclease activity of MRE 11 facilitates repair of DNA double-strand breaks. Molecular Cell, 1, 969–979.
   PubMed Web of Science ®Google Scholar
• PERRAULT, R., CHEONG, N., WANG, H., WANG, H. and ILIARis, G., 2001, RPA facilitates rejoining of DNA double-strand breaks in an in vitro assay utilizing genomic DNA as substrate. International Journal of Radiation Biology, 77, 593–607.
   PubMed Web of Science ®Google Scholar
• PETERSON, S. R., KuRams, A. A., OSIBMUR, A. M., DAN, W. S., BRADBURY, E. M. and CHEN, D. J., 1995, Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells. Proceedings of the National Academy of Sciences, USA, 92, 3171–3174.
   PubMed Web of Science ®Google Scholar
• RUSCETTI, T., LEHNERT, B. E., HALBROOK, J., LE TRONG, H., HOEKSTRA, M. F., CHEN, D. J. and PETERSON, S. R., 1998, Stimulation of the DNA-dependent protein kinase by poly(ADP-ribose) polymerase. Journal of Biological Chemistry, 273, 14461–14467.
   PubMed Web of Science ®Google Scholar
• SAMBROOK, J., FRITscx, E. F. and MANIATIS, T., 1989, Molecular Cloning: A Laboratory Manual (Cold Spring Harbor: Cold Spring Harbor Laboratory Press).
   Google Scholar
• SANZ, M. M., PROYTCHEVA, M., ELLIS, N. A., HOLLOMAN, W. K. and GERMAN, J., 2000, BLM, the Bloom's syndrome protein, varies during the cell cycle in its amount, distribution, and co-localization with other nuclear proteins. Cytogenetics and Cell Genetics, 91, 217–223.
   PubMedGoogle Scholar
• SHAO, R. G., GAO, C. X., ZHANG, H., KOHN, K. W., Won), M. S., POMMIER AND, Y., 1999, Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes. EMBO Journal, 18, 1397–1406.
   Google Scholar
• STEVENS, C. W., STAMATO, T. D., MAULDIN, S. K., GETTS, R. C., ZENG, M. and CERNIGLIA, G. J., 1999, Radiation-induced recombination is dependent on Ku80. Radiation Research, 151, 408–413.
   PubMed Web of Science ®Google Scholar
• SUZUM, K., KODAMA, S. and WATANABE, M., 1999, Recruitment of ATM protein to double strand DNA irradiated with ionizing radiation. Journal of Biological Chemistry, 274, 25571–25575.
   PubMed Web of Science ®Google Scholar
• THACKER, J., 1986, The nature of mutants induced by ionising radiation in cultured hamster cells. Mutation Research, 160, 267–275.
   PubMed Web of Science ®Google Scholar
• TRUJRU,O, K. M., YUAN, S. S., "FY, E. Y. and SUNG, P., 1998, Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mrell, and p95. Journal of Biological Chemistry, 273, 21447–21450.
   Google Scholar
• TZUNG, T. Y. and RUNGER, T. M., 1998, Reduced joining of DNA double strand breaks with an abnormal mutation spectrum in rodent mutants of DNA-PKcs and Ku80. International Journal of Radiation Biology, 73, 469–474.
   PubMed Web of Science ®Google Scholar
• WANG, Y., CORTEZ, D., YAZDI, P., NEFF, N., ELLEDGE, S. J. and QIN, J., 2000, BASC, a super complex of BRCA1-associated protein involved in the recognition and repair of aberrant DNA structures. Genes and Development, 14, 927–939.
   PubMed Web of Science ®Google Scholar
• WANG, Y., Zllou, X. Y., WANG, H., HuQ, M. S. and Iumus, G., 1999, Roles of replication protein A and DNA-dependent protein kinase in the regulation of DNA replication following DNA damage. Journal of Biological Chemistry, 274, 22060–22064.
   PubMed Web of Science ®Google Scholar
• YAMAGUCHI-IWAI, Y., SONADA, E., SASAKI, M. D., MORRISON, C., HARAGUCHI, T., HIRAKA, Y., YAMASHITA, Y. M., YAGI, T., TAKATA, M. and PRICE, C., 1999, Mrell is essential for the maintenance of chromosomal DNA in vertebrate cells. EMBO Journal, 18, 6619–6629.
   Google Scholar
• YUAN, Z. M., SHIOYA, H., ISFILKO, T., SUN, X., Gu, J., HUANG, Y. Y., Lu, H., KHARBANDA, S., WEICHSELBAUM, R. and KUFE, D., 1999, p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature, 399, 814–817.
   PubMed Web of Science ®Google Scholar
• ZHU, C., BOGUE, M. A., Lim, D.-S., HASTY, P. and ROTH, D. B., 1996, Ku86-deficient mice exhibit severe combined immunodeficiency and defective processing of V(D)J recombination intermediates. Cell, 86, 379–389.
   Google Scholar
• ZHU, X. D., KUSTER, B., MANN, M., PETRINI, J. H. and LANGE, T. D., 2000, Cell-cycle-regulated association of Rad50/ Mre 1 1 /Nbsl with TRF2 and human telomeres. Nature Genetics, 25, 347–352.
   PubMed Web of Science ®Google Scholar