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Original

Can radiation-induced apoptosis be modulated by inhibitors of energy metabolism?

, &
Pages 105-114 | Received 19 Sep 2006, Accepted 14 Nov 2006, Published online: 03 Jul 2009

References

  • Aft R L, Zhang F W, Gius D. Evaluation of 2-deoxy-D-glucose as a chemotherapeutic agent: mechanism of cell death. British Journal of Cancer 2002; 87(7)805–812
  • Belka C, Jendrossek V, Pruschy M, Vink S, Verheij M, Budach W. Apoptosis-modulating agents in combination with radiotherapy – current status and outlook. International Journal of Radiation Oncology Biology Physics 2004; 58(2)542–554
  • Chandra D, Bratton S B, Person M D, Tian Y, Martin A G, Ayres M, Fearnhead H O, Gandhi V, Tang D G. Intracellular nucleotides act as critical prosurvival factors by binding to cytochrome C and inhibiting apoptososme. Cell 2006; 125(7)1333–1346
  • Chen S J, Bradley M E, Lee T C. Chemical hypoxia triggers apoptosis of cultured neonatal rat cardiac myocytes: modulation by calcium-regulated proteases and protein kinases. Molecular and Cellular Biochemistry 1998; 178(1-2)141–149
  • Chereau D, Zou H, Spada A P, Wu J C. A nucleotide binding site in caspase-9 regulates apoptosome activation. Biochemistry 2005; 44(13)4971–4976
  • Ching T M, Ching K K. Content of adenosine phosphates and adenylate energy charge in germinating Ponderosa pine seed. Plant Physiology 1972; 50(5)536–540
  • Colussi C, Albertini M C, Coppola S, Rovidati S, Galli F, Ghibelli L. H202-induced block of glycolysis as an active ADP-ribosylation reaction protecting cells from apoptosis. The FASEB Journal 2000; 14(14)2266–2276
  • Danial N N, Gramm C F, Scooano L, Zhang C, Krauss S, Ranger A M, Datta S R, Greenberg M E, Licklider L J, Lowell B B, Gygi S P, Korsmeyer S J. BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis. Nature 2003; 424(6951)952–956
  • Dwarkanath B S, Zolzer Z, Chandana S, Bauch T, Adhikari J S, Muller W U, Streffer C, Jain V. Heterogeneity in 2-deoxy-d-glucose-induced modifications in energetics and radiation responses of human tumor cell lines. International Journal of Radiation Oncology Biology Physics 2001; 50(4)1051–1061
  • Eguchi Y, Shimizu S, Tsujimoto T. Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Research 1997; 57(10)1835–1840
  • Eguchi Y, Srinivasan A, Tomaselli K J, Shimizu S, Tsujimoto Y. ATP-dependent steps in apoptotic signal transduction. Cancer Research 1999; 59(9)2174–2181
  • Ghobrial I M, Witzig T E, Adjei A A. Targeting apoptosis pathways in cancer therapy. CA Cancer Journal for Clinicians 2005; 55(3)178–194
  • Green D, Reed J. Mitochondria and apoptosis. Science 1998; 281(5381)1309–1312
  • Gutmann I, Wahlefeld A W. L-(+)-Lactate determination with lactate dehydrogenase and NAD. Methods of enzymatic analysis, Volume 3, 2nd ed., H U Bergmeyer. Verlag Chemie, New York 1974; 1464–1468
  • Haga N, Naito M, Seimiya H, Tomida A, Dong J, Tsuruo T. 2-Deoxyglucose inhibits chemotherapeutic drug-induced apoptosis in human monocytic leukemia u937 cells with inhibition of c-jun n-terminal kinase 1/stress-activated protein kinase activation. International Journal of Cancer 1998; 76(1)86–90
  • Halicka H D, Ardelt B, Li X, Melamed M M, Darzynkiewicz Z. 2-Deoxyglucose enhances sensitivity of human histiocytic lymphoma u937 cells to apoptosis induced by tumor necrosis factor. Cancer Research 1995; 55(2)444–449
  • Hao J H, Yu M, Liu F T, Newland A C, Jia L. Bcl-2 inhibitors sensitize tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by uncoupling of mitochondrial respiration in human leukemic CEM cells. Cancer Research 2004; 64(10)3607–3616
  • Hunter A J, Blekkenhorst G H. The effects of 2-deoxyglucose and amino-oxyacetic acid on the radiation response of mammalian cells in vitro. International Journal of Radiation Biology 1998; 73(3)311–324
  • Izymov D S, Avetisyan A V, Pletjushkina O Y, Sakharov D V, Wirtz K W, Chernyak B V, Skulachev V P. “Wages of fear”: transient threefold decrease in intracellular ATP level imposes apoptosis. Biochimica et Biophysica Acta 2004; 1658(1-2)141–147
  • Jain V K, Porschen W, Feinendegen L E. Optimization of cancer therapy: Part II – Effects of combining 2-deoxy-D-glucose treatment with gamma-irradiation on sarcoma-180. Indian Journal of Experimental Biology 1977a; 15(9)714–718
  • Jain V K, Purohit S C, Pohlit W. Optimization of cancer therapy: Part I – Inhibition of repair of X-ray induced potentially lethal damage by 2-deoxy-D-glucose in Erlich-ascites tumour cells. Indian Journal of Experimental Biology 1977b; 15(9)711–713
  • Jeong D W, Kim T S, Cho I T, Kim I Y. Modification of glycolysis affects cell sensitivity to apoptosis induced by oxidative stress and mediated by mitochondria. Biochemical and Biophysical Research Communications 2004; 313(4)984–991
  • Kelly S K, Ashkenazi A. Targeting death receptors in cancer with Apo2L/TRAIL. Current Opinion in Pharmacology 2004; 4(4)333–339
  • Lee J, Paull T T. ATM activation by DNA doublestrand breaks through the Mre11-Rad50-Nbs1 complex. Science 2005; 308(5721)551–554
  • Li P, Nijhawan D, Budihardojo I, Srinivasula S M, Ahmad M, Alnemri E S, Wang X. Cytochrome c and dATP-dependent formation of apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997; 91(4)479–489
  • Liu X, Kim C N, Yang J, Jemmerson R, Wang X. Induction of apoptotic program in cell free extracts: requirement for dATP and cytochrome c. Cell 1996; 86(1)147–157
  • Mohanti B K, Rath G K, Anantha N, Kannan V, Das B S, Chandramouli B A, Banerjee A K, Das S, Jena A, Ravichandran R, Sahi U P, Kumar R, Kapoor N, Kalia V K, Dwarakanath B S, Jain V. Improving cancer radiotherapy with 2-deoxy-D-glucose: phase I/II clinical trials on human cerebral gliomas. International Journal of Radiation Oncology Biology Physics 1996; 35(1)103–111
  • Munoz-Pinedo C, Ruiz-Ruiz C, Ruiz de Almodovar C, Palacios C, Lopez-Rivas A. Inhibition of glucose metabolism sensitizes tumor cells to death receptor-triggered apoptosis through enhancement of death-inducing signaling complex formation and apical procaspase-8 processing. Journal of Biological Chemistry 2003; 278(15)12759–12768
  • Seymour C B, Mothersill C, Moriarty M J. Glucose analogues alter the response of CHO-k1 cells to gamma irradiation. Acta Radiologica Oncology 1985; 24(4)351–356
  • Shinomiya N, Kuno Y, Yamamoto F, Fukasawa M, Okumura A, Uefuji M, Rokutanda M. Different mechanisms between premitotic apoptosis and postmitotic apoptosis in X-irradiated U937 cells. International Journal of Radiation Oncology Biology Physics 2000; 47(3)767–777
  • Stanley P E, Williams S G. Use of the liquid scintillation spectrometer for determining adenosine triphosphate by the luciferase enzyme. Analytical Biochemistry 1969; 29(3)381–392
  • TH-CR-101, (Clinicaltrials.gov identifier NCT00096707) http://www.clinicaltrials.gov
  • Vaux D L, Whitney D, Weissman I L. Activation of physiological cell death mechanisms by a necrosis-causing agent. Microscopy Research and Technique 1996; 34(3)259–266
  • Verheij M, Bartelink H. Radiation-induced apoptosis. Cell Tissue Research 2000; 301(1)133–142
  • Verheij M, Bose R, Lin X H, Yao B, Jarvis W D, Grant S, Birrer M J, Szabo E, Zon L I, Kyriakis J M, Haimovitz-Friedman A, Fuks Z, Kolesnick R N. Requirement for ceramide-initiated SAPK/JNK signaling in stress-induced apoptosis. Nature 1996; 380(6569)75–79
  • Wei Q, Alam M M, Wang M H, Yu F, Dong Z. Bid activation in kidney cells following ATP depletion in vitro and ischaemia in vivo. American Journal of Physiology - Renal Physiology 2004; 286(4)F803–F809
  • Wilhelm S, Roloff S, Hacker G. Inhibition of etoposide-induced apoptotic events by azide. Immunology Letters 1997; 59(1)53–59
  • Xu R H, Pelicano H, Zhou Y, Carew J S, Feng L, Bhalla K N, Keating M J, Huang P. Cancer Research 2005; 65(2)613–621
  • Yang N C, Ho W M, Chen Y H, Hu M L. A convenient one-step extraction of cellular ATP using boiling water for the luciferin-luciferase assay of ATP. Analytical Biochemistry 2002; 306(2)323–327
  • Yasuhara N, Eguchi Y, Tachibana T, Imamoto N, Yoneda Y, Tsujimoto Y. Essential role of active nuclear transport in apoptosis. Genes to Cells 1997; 2(1)55–64
  • Zou H, Li Y, Liu X, Wang X. An apaf-1-cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9. Journal of Biological Chemistry 1999; 274(17)11549–11556

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