Sensors of ionizing radiation effects on the immunological microenvironment of cancer

References

• Barcellos-Hoff M H, Park C, Wright E G. Radiation and the microenvironment – tumorigenesis and therapy. Nature Reviews Cancer 2005; 5: 867–875
   PubMed Web of Science ®Google Scholar
• Benlagha K, Bendelac A. CD1d-restricted mouse V alpha 14 and human V alpha 24 T cells: Lymphocytes of innate immunity. Seminars in Immunology 2000; 12: 537–542
   PubMed Web of Science ®Google Scholar
• Bissell M J, Kenny P A, Radisky D C. Microenvironmental regulators of tissue structure and function also regulate tumor induction and progression: The role of extracellular matrix and its degrading enzymes. Cold Spring Harbor Symposia on Quantitative Biology 2005; 70: 343–356
   PubMedGoogle Scholar
• Burnet M. Cancer: A biological approach. British Medical Journal 1957; 1: 841–847
   PubMed Web of Science ®Google Scholar
• Carlos T M. Leukocyte recruitment at sites of tumor: Dissonant orchestration. Journal of Leukocyte Biology 2001; 70: 171–184
   PubMed Web of Science ®Google Scholar
• Cella M, Sallusto F, Lanzavecchia A. Origin, maturation and antigen presenting function of dendritic cells. Current Opinion in Immunology 1997; 9: 10–16
   PubMed Web of Science ®Google Scholar
• Chakraborty M, Abrams S I, Camphausen K, Liu K, Scott T, Coleman C N, Hodge J W. Irradiation of tumor cells up-regulates Fas and enhances CTL lytic activity and CTL adoptive immunotherapy. Journal of Immunology 2003; 170: 6338–6347
   PubMed Web of Science ®Google Scholar
• Chakravarty P K, Alfieri A, Thomas E K, Beri V, Tanaka K E, Vikram B, Guha C. Flt3-Ligand administration after radiation therapy prolongs survival in a murine model of metastatic lung cancer. Cancer Research 1999; 59: 6028–6032
   PubMed Web of Science ®Google Scholar
• Chen Q, Wang W C, Evans S S. Tumor microvasculature as a barrier to antitumor immunity. Cancer Immunology Immunotherapy 2003; 52: 670–679
   PubMed Web of Science ®Google Scholar
• Chiang C S, Syljuasen R G, Hong J H, Wallis A, Dougherty G J, McBride W H. Effects of IL-3 gene expression on tumor response to irradiation in vitro and in vivo. Cancer Research 1997; 57: 3899–3903
   PubMed Web of Science ®Google Scholar
• Curiel T J, Coukos G, Zou L, Alvarez X, Cheng P, Mottram P, Evdemon-Hogan M, Conejo-Garcia J R, Zhang L, Burow M, Zhu Y, Wei S, Kryczek I, Daniel B, Gordon A, Myers L, Lackner A, Disis M L, Knutson K L, Chen L, Zou W. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nature Medicine 2004; 10: 942–949
   PubMed Web of Science ®Google Scholar
• Dallal R M, Lotze M T. The dendritic cell and human cancer vaccines. Current Opinion in Immunology 2000; 12: 583–588
   PubMed Web of Science ®Google Scholar
• Demaria S, Kawashima N, Yang A M, Devitt M -L, Babb J S, Allison J P, Formenti S C. Immune-mediated inhibition of metastases following treatment with local radiation and CTLA-4 blockade in a mouse model of breast cancer. Clinical Cancer Research 2005a; 11: 728–734
   PubMed Web of Science ®Google Scholar
• Demaria S, Ng B, Devitt M -L, Babb J S, Kawashima N, Liebes L, Formenti S C. Ionizing radiation inhibition of distant untreated tumors (abscopal effect) is immune mediated. International Journal of Radiation Oncology, Biology, Physics 2004; 58: 862–870
   PubMed Web of Science ®Google Scholar
• Demaria S, Santori F R, Ng B, Liebes L, Formenti S C, Vukmanovic S. Select forms of tumor cell apoptosis induce dendritic cell maturation. Journal of Leukocyte Biology 2005b; 77: 361–368
   PubMed Web of Science ®Google Scholar
• Dunn G P, Bruce A T, Ikeda H, Old L J, Schreiber R D. Cancer immunoediting: From immunosurveillance to tumor escape. Nature Immunology 2002; 3: 991–998
   PubMed Web of Science ®Google Scholar
• Egen J G, Kuhns M S, Allison J P. CTLA-4: New insights into its biological function and use in tumor immunotherapy. Nature Immunology 2002; 3: 611–618
   PubMed Web of Science ®Google Scholar
• Gabrilovich D I, Chen H L, Girgis K R, Cunningham H T, Meny G M, Nadaf S, Kavanaugh D, Carbone D P. Production of vascular endothelial growth factor by human tumors inhibits the functional maturation of dendritic cells. Nature Medicine 1996; 2: 1096–1103
   PubMed Web of Science ®Google Scholar
• Gajewski T F, Meng Y, Blank C, Brown I, Kacha A, Kline J, Harlin H. Immune resistance orchestrated by the tumor microenvironment. Immunological Reviews 2006; 213: 131–145
   PubMed Web of Science ®Google Scholar
• Galon J, Costes A, Sanchez-Cabo F, Kirilovsky A, Mlecnik B, Lagorce-Pages C, Tosolini M, Camus M, Berger A, Wind P, Zinzindohoue F, Bruneval P, Cugnenc P H, Trajanoski Z, Fridman W H, Pages F. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 2006; 313: 1960–1964
   PubMed Web of Science ®Google Scholar
• Ganss R, Ryschich E, Klar E, Arnold B, Hammerling G J. Combination of T-cell therapy and trigger of inflammation induces remodeling of the vasculature and tumor eradication. Cancer Research 2002; 62: 1462–1470
   PubMed Web of Science ®Google Scholar
• Garnett C T, Palena C, Chakarborty M, Tsang K Y, Schlom J, Hodge J W. Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes. Cancer Research 2004; 64: 7985–7994
   PubMed Web of Science ®Google Scholar
• Gaugler M H, Squiban C, van der Meeren A, Bertho J M, Vandamme M, Mouthon M A. Late and persistent up-regulation of intercellular adhesion molecule-1 (ICAM-1) expression by ionizing radiation in human endothelial cells in vitro. International Journal of Radiation Biology 1997; 72: 201–209
   PubMed Web of Science ®Google Scholar
• Hallahan D, Kuchibhotla J, Wyble C. Cell adhesion molecules mediate radiation-induced leukocyte adhesion to the vascular endothelium. Cancer Research 1996; 56: 5150–5155
   PubMed Web of Science ®Google Scholar
• Hallahan D E, Virudachalam S. Accumulation of P-selectin in the lumen of irradiated blood vessels. Radiation Research 1999; 152: 6–13
   PubMed Web of Science ®Google Scholar
• Hareyama M, Imai K, Kubo K, Takahashi H, Koshiba H, Hinoda Y, Shidou M, Oouchi A, Yachi A, Morita K. Effect of radiation on the expression of carcinoembryonic antigen of human gastric adenocarcinoma cells. Cancer 1991; 67: 2269–2274
   PubMed Web of Science ®Google Scholar
• Jain R K. Transport of molecules, particles, and cells in solid tumors. Annual Review of Biomedical Engineering 1999; 1: 241–263
   PubMed Web of Science ®Google Scholar
• Kim K W, Kim S H, Shin J G, Kim G S, Son Y O, Park S W, Kwon B H, Kim D W, Lee C H, Sol M Y, Jeong M H, Chung B S, Kang C D. Direct injection of immature dendritic cells into irradiated tumor induces efficient antitumor immunity. International Journal of Cancer 2004; 109: 685–690
   PubMed Web of Science ®Google Scholar
• Kusmartsev S, Gabrilovich D I. Immature myeloid cells and cancer-associated immune suppression. Cancer Immunology Immunotherapy 2002; 51: 293–298
   PubMed Web of Science ®Google Scholar
• Larsson M, Fonteneau J F, Bhardwaj N. Dendritic cells resurrect antigens from dead cells. Trends in Immunology 2001; 22: 141–148
   PubMed Web of Science ®Google Scholar
• Lugade A A, Moran J P, Gerber S A, Rose R C, Frelinger J G, Lord E M. Local radiation therapy of B16 melanoma tumors increases the generation of tumor antigen-specific effector cells that traffic to the tumor. Journal of Immunology 2005; 174: 7516–7523
   PubMed Web of Science ®Google Scholar
• Marincola F M, Jaffee E M, Hicklin D J, Ferrone S. Escape of human solid tumors from T-cell recognition: Molecular mechanisms and functional significance. Advances in Immunology 2000; 74: 181–273
   PubMedGoogle Scholar
• Mason K A, Ariga H, Neal R, Valdecanas D, Hunter N, Krieg A M, Whisnant J K, Milas L. Targeting toll-like receptor 9 with CpG oligodeoxynucleotides enhances tumor response to fractionated radiotherapy. Clinical Cancer Research 2005; 11: 361–369
   PubMed Web of Science ®Google Scholar
• Matzinger P. Tolerance, danger, and the extended family. Annual Review of Immunology 1994; 12: 991–1045
   PubMed Web of Science ®Google Scholar
• McBride W H, Chiang C -S, Olson J L, Wang C -C, Hong J -H, Pajonk F, Dougherty G J, Iwamoto K S, Pervan M, Liao Y -P. A sense of danger from radiation. Radiation Research 2004; 162: 1–19
   PubMed Web of Science ®Google Scholar
• Melief C JM. Tumor eradication by adoptive transfer of cytotoxic T lymphocytes. Advances in Cancer Research 1992; 58: 143–175
   PubMed Web of Science ®Google Scholar
• Newcomb E W, Demaria S, Lukyanov Y, Shao Y, Schnee T, Kawashima N, Lan L, Dewyngaert J K, Zagzag D, McBride W H, Formenti S C. The combination of ionizing radiation and peripheral vaccination produces long-term survival of mice bearing established invasive GL261 gliomas. Clinical Cancer Research 2006; 12: 4730–4737
   PubMed Web of Science ®Google Scholar
• Nikitina E Y, Gabrilovich D I. Combination of gamma-irradiation and dendritic cell administration induces a potent antitumor response in tumor-bearing mice: Approach to treatment of advanced stage cancer. International Journal of Cancer 2001; 94: 825–833
   PubMed Web of Science ®Google Scholar
• O'Neill D W, Adams S, Bhardwaj N. Manipulating dendritic cell biology for the active immunotherapy of cancer. Blood 2004; 104: 2235–2246
   PubMed Web of Science ®Google Scholar
• Obeid M, Tesniere A, Ghiringhelli F, Fimia G M, Apetoh L, Perfettini J L, Castedo M, Mignot G, Panaretakis T, Casares N, Metivier D, Larochette N, van Endert P, Ciccosanti F, Piacentini M, Zitvogel L, Kroemer G. Calreticulin exposure dictates the immunogenicity of cancer cell death. Nature Medicine 2007; 13: 54–61
   PubMed Web of Science ®Google Scholar
• Reits E A, Hodge J W, Herberts C A, Groothuis T A, Chakraborty M, Wansley E K, Camphausen K, Luiten R M, de Ru A H, Neijssen J, Griekspoor A, Mesman E, Verreck F A, Spits H, Schlom J, van Veelen P, Neefjes J J. Radiation modulates the peptide repertoire, enhances MHC class I expression, and induces successful antitumor immunotherapy. Journal of Experimental Medicine 2006; 203: 1259–1271
   PubMed Web of Science ®Google Scholar
• Rock K L, Goldberg A L. Degradation of cell proteins and the generation of MHC class I-presented peptides. Annual Review of Immunology 1999; 17: 739–779
   PubMed Web of Science ®Google Scholar
• Sauter B, Albert M L, Francisco L, Larsson M, Somersan S, Bhardwaj N. Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. Journal of Experimental Medicine 2000; 191: 423–433
   PubMed Web of Science ®Google Scholar
• Serafini P, De Santo C, Marigo I, Cingarlini S, Dolcetti L, Gallina G, Zanovello P, Bronte V. Derangement of immune responses by myeloid suppressor cells. Cancer Immunology Immunotherapy 2004; 53: 64–72
   PubMed Web of Science ®Google Scholar
• Shankaran V, Ikeda H, Bruce A T, White J M, Swanson P E, Old L J, Schreiber R D. IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 2001; 410: 1107–1111
   PubMed Web of Science ®Google Scholar
• Shimizu J, Yamazaki S, Sakaguchi S. Induction of tumor immunity by removing CD25 + CD4+ T cells: A common basis between tumor immunity and autoimmunity. Journal of Immunology 1999; 163: 5211–5218
   PubMed Web of Science ®Google Scholar
• Skoberne M, Beignon A S, Bhardwaj N. Danger signals: A time and space continuum. Trends in Molecular Medicine 2004; 10: 251–257
   PubMed Web of Science ®Google Scholar
• Smyth M J, Godfrey D I, Trapani J A. A fresh look at tumor immunosurveillance and immunotherapy. Nature Immunology 2001; 2: 293–299
   PubMed Web of Science ®Google Scholar
• Teitz-Tennenbaum S, Li Q, Rynkiewicz S, Ito F, Davis M A, McGinn C J, Chang A E. Radiotherapy potentiates the therapeutic efficacy of intratumoral dendritic cell administration. Cancer Research 2003; 63: 8466–8475
   PubMed Web of Science ®Google Scholar
• Thomas L. Discussion. Cellular and humoral aspects of the hypersensitive states, H S Lawrence. Hoeber-Harper, New York 1959; 529–532
   Google Scholar
• Wang T, Niu G, Kortylewski M, Burdelya L, Shain K, Zhang S, Bhattacharya R, Gabrilovich D I, Heller R, Coppola D, Dalton W, Jove R, Pardoll D, Yu H. Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells. Nature Medicine 2004; 10: 48–54
   PubMed Web of Science ®Google Scholar
• Wersall P J, Blomgren H, Pisa P, Lax I, Kalkner K M, Svedman C. Regression of non-irradiated metastases after extracranial stereotactic radiotherapy in metastatic renal cell carcinoma. Acta Oncologica 2006; 45: 493–497
   PubMed Web of Science ®Google Scholar
• Yu P, Lee Y, Liu W, Krausz T, Chong A, Schreiber H, Fu Y X. Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors. Journal of Experimental Medicine 2005; 201: 779–791
   PubMed Web of Science ®Google Scholar
• Zagzag D, Salnikow K, Chiriboga L, Yee H T, Lan L, Ali M A, Garcia R, Demaria S, Newcomb E W. Downregulation of major histocompatibility complex antigens in invading glioma cells: Stealth invasion of the brain. Laboratory Investigation 2005; 85: 328–341
   PubMed Web of Science ®Google Scholar
• Zhang B, Bowerman N A, Salama J K, Schmidt H, Spiotto M T, Schietinger A, Yu P, Fu Y X, Weichselbaum R R, Rowley D A, Kranz D M, Schreiber H. Induced sensitization of tumor stroma leads to eradication of established cancer by T cells. Journal of Experimental Medicine 2007; 204: 49–55
   PubMed Web of Science ®Google Scholar