78
Views
17
CrossRef citations to date
0
Altmetric
Integrins and the Cellular Radiation Response

alpha6 Integrin Cleavage: Sensitizing human prostate cancer to ionizing radiation

, , , , , & show all
Pages 761-767 | Received 02 Apr 2007, Accepted 10 Aug 2007, Published online: 03 Jul 2009

References

  • Barcellos-Hoff M H. Radiation-induced transforming growth factor beta and subsequent extracellular matrix reorganization in murine mammary gland. Cancer Research 1993; 53: 3880–3886
  • Barcellos-Hoff M H, Park C, Wright E G. Radiation and the microenvironment – tumorigenesis and therapy. Nature Reviews Cancer 2005; 5: 867–875
  • Bissery M C, Guenard D, Gueritte-Voegelein F, Lavelle F. Experimental antitumor activity of taxotere (RP 56976, NSC 628503), a taxol analogue. Cancer Research 1991; 51: 4845–4852
  • Brouty-Boye D, Raux H, Azzarone B, Tamboise A, Tamboise E, Beranger S, Magnien V, Pihan I, Zardi L, Israel L. Fetal myofibroblast-like cells isolated from post-radiation fibrosis in human breast cancer. International Journal of Cancer 1991; 47: 697–702
  • Chen X, Gumbiner B M. Crosstalk between different adhesion molecules. Current Opinion in Cell Biology 2006; 18: 572–578
  • Cordes N. Cell adhesion-mediated radiation resistance: The role of integrins and integrin proximal protein. Cell adhesion and cytoskeletal molecules in metastasis Cancer Metastasis-Biology and Treatment, Volume 9, A W Cress, R B Nagle, R. J. A. a. W. G. Jiang. Springer, Dordrecht, The Netherlands. Editors RJ Ablin and WG Jiang. 2006; 141–162
  • Cordes N, Meineke V. Cell adhesion-mediated radioresistance (CAM-RR). Extracellular matrix-dependent improvement of cell survival in human tumor and normal cells in vitro. Strahlentherapie und Onkology 2003; 179: 337–344
  • Damiano J S. Integrins as novel drug targets for overcoming innate drug resistance. Current Cancer Drug Targets 2002; 2: 37–43
  • Davis T L, Rabinovitz I, Futscher B W, Schnolzer M, Burger F, Liu Y, Kulesz-Martin M, Cress A E. Identification of a novel structural variant of the alpha 6 integrin. Journal of Biological Chemistry 2001; 276: 26099–26106
  • Demetriou M C, Pennington M E, Nagle R B, Cress A E. Extracellular alpha 6 integrin cleavage by urokinase-type plasminogen activator in human prostate cancer. Experimental Cell Research 2004; 294: 550–558
  • Hehlgans S, Haase M, Cordes N. Signalling via integrins: Implications for cell survival and anticancer strategies. Biochimica et Biophysica Acta 2007; 1775: 163–180
  • Hummerich J, Werle-Schneider G, Popanda O, Celebi O, Chang-Claude J, Kropp S, Mayer C, Debus J, Bartsch H, Schmezer P. Constitutive mRNA expression of DNA repair-related genes as a biomarker for clinical radio-resistance: A pilot study in prostate cancer patients receiving radiotherapy. International Journal of Radiation Biology 2006; 82: 593–604
  • Jemal A, Siegel R, Ward E, Murray T, Xu J, Thun M J. Cancer statistics, 2007. CA A Cancer Journal for Clinicians 2007; 57: 43–66
  • Kremer C L, Schmelz M, Cress A E. Integrin-dependent amplification of the G2 arrest induced by ionizing radiation. Prostate 2006; 66: 88–96
  • Kupelian P A, Mohan D S, Lyons J, Klein E A, Reddy C A. Higher than standard radiation doses (> or = 72 Gy) with or without androgen deprivation in the treatment of localized prostate cancer. International Journal of Radiation Oncology, Biology, Physics 2000; 46: 567–574
  • Livsey J E, Wylie J P, Swindell R, Khoo V S, Cowan R A, Logue J P. Do differences in target volume definition in prostate cancer lead to clinically relevant differences in normal tissue toxicity?. International Journal of Radiation Oncology, Biology, Physics 2004; 60: 1076–1081
  • Lotan Y, Stanfield J, Cho L C, Sherwood J B, Abdel-Aziz K F, Chang C H, Forster K, Kabbani W, Hsieh J T, Choy H, Timmerman R. Efficacy of high dose per fraction radiation for implanted human prostate cancer in a nude mouse model. Journal of Urology 2006; 175: 1932–1936
  • Parker W, Patrocinio H. Practical aspects of inverse-planned intensity-modulated radiation therapy for prostate cancer: A radiation treatment planner's perspective. Canadian Journal of Urology 2005; 12(Suppl 2)48–52
  • Pawar S C, Demetriou M C, Nagle R B, Bowden G T, Cress A E. Integrin alpha6 cleavage: A novel modification to modulate cell migration. Experimental Cell Research 2007; 313: 1080–1089
  • Remy J, Wegrowski J, Crechet F, Martin M, Daburon F. Long-term overproduction of collagen in radiation-induced fibrosis. Radiation Research 1991; 125: 14–19
  • Schmelz M, Cress A E, Scott K M, Burger F, Cui H, Sallam K, McDaniel K M, Dalkin B L, Nagle R B. Different phenotypes in human prostate cancer: alpha6 or alpha3 integrin in cell-extracellular adhesion sites. Neoplasia 2002; 4: 243–254
  • Tamura R N, Rozzo C, Starr L, Chambers J, Reichardt L F, Cooper H M, Quaranta V. Epithelial integrin alpha 6 beta 4: Complete primary structure of alpha 6 and variant forms of beta 4. Journal of Cell Biology 1990; 111: 1593–1604
  • Tran N L, Nagle R B, Cress A E, Heimark R L. N-Cadherin expression in human prostate carcinoma cell lines. An epithelial-mesenchymal transformation mediating adhesion with Stromal cells. American Journal of Pathology 1999; 155: 787–798
  • Valdagni R, Italia C, Montanaro P, Lanceni A, Lattuada P, Magnani T, Fiorino C, Nahum A. Is the alpha-beta ratio of prostate cancer really low? A prospective, non-randomized trial comparing standard and hyperfractionated conformal radiation therapy. Radiotherapy & Oncology 2005; 75: 74–82

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.