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ELF-EMF and Planarian Regeneration

Extremely low frequency electromagnetic fields activate the ERK cascade, increase hsp70 protein levels and promote regeneration in Planaria

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Pages 851-859 | Received 18 Nov 2008, Accepted 07 May 2009, Published online: 08 Oct 2009

References

  • Agata K. Regeneration and gene regulation in planarians. Current Opinion in Genetic Development 2003; 13: 492–496
  • Agata K, Umesono Y. Brain regeneration from pluripotent stem cells in planarian. Philosophila Transactions of the Royal Society B 2008; 363: 2071–2078
  • Albertini A, Zucchini P, Noera G, Cadossi R, Napoleone C P, Pierangeli A. Protective effect of low frequency low energy pulsing electromagnetic fields on actute experimental myocardial infarcts in rats. Bioelectromagnetics 1999; 20: 372–377
  • Agata K, Soejima Y, Kato K, Kobayashi C, Umesono Y, Watanabe K. Structure of the planarian central nervous system (CNS) revealed by neuronal cell markers. Zoological Society 1998; 15: 433–440
  • Ambron R T, Dulin M F, Zhang X P, Schmied R, Walters E T. Axoplasm enriched in a protein mobilized by nerve injury induces memory-like alterations in Aplysia neurons. Journal of Neuroscience 1995; 15: 3440–3446
  • Baguna J, Romero R. Quantitative analysis of cell types during growth, regrowth and regeneration in the planarians Digesia mediterranea and Dugesia tigrina. Hydrobiologia 1981; 84: 181–194
  • Bassett C AL. Bioelectromagnetics in the service of medicine. Advances in Chemistry 1995; 250: 261–276
  • Blank M, Goodman R. Do electromagnetic fields interact directly with DNA?. Bioelectromagnetics 1997; 18: 111–115
  • Carmody S, Wu X L, Lin H, Blank M, Skopicki H, Goodman R. Cytoprotection by electromagnetic field-induced hsp70: A model for clinical application. Journal of Cellular Biochemistry 2000; 79: 453–459
  • Cebria F, Kudome T, Nakazawa M, Mineta K, Ikeo K, Gojobori T, Agata K. The expression of neural-specific genes reveals the structural and molecular complexity of the planarian central nervous system. Mechanistic Development 2002a; 116: 199–204
  • Cebria F, Nakazawa M, Mineta K, Ikeo K, Gojobori T, Agata K. Dissecting planarian central nervous system regeneration by the expression of neural-specific genes. Developmental Growth & Differentiation 2002b; 44: 135–146
  • Cebria F, Nakazawa M, Mineta K, Ikeo K, Gojobori T, Agata K. Dissecting planarian central nervous system regeneration by the expression of neural-specific genes Developmental Growth & Differentiation. 2002c; 44: 135–146
  • DiCarlo A L, Farrell J M, Litovitz T A. Myocardial protection conferred by electromagnetic fields. Circulation 1999; 99: 813–816
  • Friedman J, Kraus S, Hauptman Y, Schiff Y, Seger R. Mechanism of short-term ERK activation by electromagnetic fields at mobile phone frequencies. Biochemistry Journal 2007; 405: 559–568
  • George I, Geddis M S, Lill Z, Lin H, Gomez T, Blank M, Oz M C, Goodman R. Myocardial function improved by electromagnetic field induction of stress protein hsp70. Journal of Cellular Biochemistry 2008, DOI: 10.1002/jcp21461
  • Gille H, Kortenjann M, Thomae O, Moomaw C, Slaughter C, Cobb M H, Shaw P E. ERK phosphorylation potentiates Elk-1-mediated ternary complex formation and transactivation. EMBO Journal 1995; 14: 951–962
  • Goodman R, Wei L-X, Xu J-C, Henderson A. Exposure of human cells to low-frequency electromagnetic fields results in quantitative changes in transcripts. Biochim et Biophys Acta 1989; 1009: 216–220
  • Goodman R, Weisbrot D, Uluc A, Henderson A. Transcription in Drosophila melanogaster salivary gland cells is altered following exposure to low frequency electromagnetic fields: Analysis of chromosome 3R. Bioelectromagnetics 1992; 13: 111–118
  • Goodman R, Bumann J. Electromagnetics in Biology and Medicine, C T Brighton, S R Pollack. San Francisco Press Inc., San Francisco, CA 1991
  • Goodman R, Blank M. Magnetic field stress induces expression of hsp70. Cell Stress & Chaperones 1998; 3: 79–88
  • Goodman R, Blank M. Insights into electromagnetic interaction mechanisms. Journal of Cellular Physiology 2002; 192: 16–22
  • Goodman R, Blank M, Lin H, Khorkova O, Soo L, Weisbrot D, Henderson A. Increased levels of hsp70 transcripts are induced when cells are exposed to low frequency electromagnetic fields. Bioelectrochemistry Bioenergetics 1994; 33: 115–120
  • Goodman R, Henderson A S. Exposure of salivary gland cells to low-frequency electromagnetic fields alters polypeptide synthesis. Proceeding of the National Academy of Science of the USA 1988; 85: 3928–3932
  • Goodman R, Bumann J, Wei L-X, Henderson A S. Exposure of human cells to electromagnetic fields: Effect of time and field strength on transcript levels. Electro-and Magnetobiology 1992; 11: 19–28
  • Gordon G. Designed electromagnetoic pulsed therapy: Clinical applications. Journal of Cellular Physiology 2006, DOI 10.1002/JCP
  • Gordon G. Extrinsic electromagnetic fields, low frequency (phonon) vibrations and control of cell function: A non-linear resonance system. Journal Biomedical Science and Engineering 2008; 1: 152–156
  • Han L, Lin H, Head M, Jin M, Blank M, Goodman R. Application of magnetic field-induced heat shock protein 70 for presurgical cytoprotection. Journal of Cellular Biochemistry 1998; 71: 577–583
  • Jenrow K A, Smith C H, Liboff A R. Weak extremely-l ow frequency magnetic fields and regeneration in the planarian Dugesia tigrina. Bioelectromagnetics 1995; 16: 106–112
  • Jenrow K A, Smith C H, Liboff A R. Weak extremely-low frequency magnetic field-induced regeneration anomalies in the planarian Dugesia tigrina. Bioelectromagnetics 1985; 17: 467–474
  • Jin M, Blank M, Goodman R. ERK1/2 phosphorylation, induced by electromagnetic fields, diminishes during neoplastic transformation. Journal of Cellular Biochemistry 1996; 78: 371–379
  • Jin M, Lin H, Han L, Opler M, Maurer S, Blank M, Goodman R. Biological and technical variables in myc expression in HL60 cells exposed to 60 Hz electromagnetic fields. Bioelectrochemistry Bioenergetics 1997; 44: 111–120
  • Kultz D. Molecular and evolutionary basis of the cellular stress response. Annual Review of Physiology 2005; 67: 225–257
  • Leszczynski D, Joenvaara S, Reivinen J, Kuokka R. Non-thermal activation of the hsp27/p38MAPK stress pathway by mobile phone radiation in human endothelial cells: Molecular mechanism for cancer- and blood-brain barrier-related effects. Differentiation 2002; 70: 120–129
  • Lin H, Bao J, Sung Y J, Walters E T, Ambron R T. Rapid electrical and delayed molecular signals regulate the serum response element after nerve injury: Convergence of injury and learning signals. Journal of Neurobiology 2003; 57: 204–220
  • Lin H, Blank M, Goodman R. A magnetic field-responsive domain in the human HSP70 promoter. Journal Cellular Biochemistry 1999; 75: 170–176
  • Lin H, Blank M, Rossol-Haseroth K, Goodman R. Regulating genes with electromagnetic response elements. Journal of Cellular Biochemistry 2001; 81: 143–148
  • Lin H, Han L, Blank M, Head M, Goodman R. Magnetic field activation of protein-DNA binding. Journal of Cellular Biochemistry 1998a; 70: 297–303
  • Lin H, Head M, Blank M, Han L, Jin M, Goodman R. Myc-mediated transactivation of HSP70 expression following exposure to magnetic fields. Journal of Cellular Biochemistry 1998b; 69: 181–188
  • Lin H, Opler M, Head M, Blank M, Goodman R. Electromagnetic field exposure induces rapid, transitory heat shock factor activation in human cells. Journal of Cellular Biochemistry 1997; 66: 482–488
  • Newmark P A, Sanchez Alvarado A. Regeneration in Planaria. Encyclopedia of Life Sciences. 2001, www.els.net
  • Marais R, Wynne J, Treisman R. The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain. Cell 1993; 73: 381–393
  • Morimoto R I. Regulation of the heat shock transcriptional response: cross talk between a family of heat shock factors, molecular chaperones and negative regulators. Genes & Development 1998; 12: 3788–3796
  • Novikov V V, Sheiman I M, Fesenko E E. Effect of weak static and low-frequency alternating magnetic fields on the fission and regeneration of the planarian dugesia (Girardia) tigrina. Bioelectromagnetics Jul, 2008; 29(5)29387–393
  • Rao S, Henderson A S. Regulation of c-fos is affected by electromagnetic fields. Journal of Cellular Biochemistry 1996; 63: 358–365
  • Sanchez Alvarado A, Newmark P A, Robb S M, Juste R. The Schmidtea mediterranea database as a molecular resource for studying platyhelminths, stem cells and regeneration. Development 2002; 129: 5659–5665
  • Sanchez Alvarado A. The fresh water planarian Schmidtea mediterranea: Embryogenesis, stem cells and regeneration. Current Opinion in Genetics & Development 2003; 13: 438–444
  • Sanchez Alvarado A, Newmark P A, Robb S M, Juste R. The Schmidtea mediterranea database as a molecular resource for studying platyhelminths, stem cells and regeneration. Development 2002; 129: 5659–5665
  • Shallom J M, Di Carlo A L, Ko D, Penafiel L M, Nakai A, Litovitz T A. Microwave exposure induces Hsp70 and confers protection against hypoxia in chick embryos. Journal of Cellular Biochemistry 2002; 86: 490–496
  • Sung Y J, Ambron R T. Pathways that elicit long-term changes in gene expression in noniceptive neuron following nerve injury contributions to neuropathic pain. Neurological Research 2004; 26: 195–203
  • Sung Y J, Chiu D TW, Ambron R T. Activation and retrograde transport of protein kinase G in rat noniceptive neurons after nerve injury and inflammation. Neuroscience 2006; 141: 697–709
  • Weisbrot D, Khorkova O, Lin H, Henderson A, Goodman R. The effect of low frequency electric and magnetic fields on gene expression in Saccharomyces cerevisiae Bioelectrochemistry Bioenergetics. 1993; 31: 167–177
  • Weisbrot D, Lin H, Ye L, Blank M, Goodman R. Effects of mobile phone radiation on reproduction and development in Drosophila melanogaster. Journal of Cellular Biochemistry 2003; 89: 48–55

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