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Research Article

Cytogenetic damage of radiotherapy in long-term head and neck cancer survivors

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Pages 364-370 | Received 09 Oct 2015, Accepted 24 Mar 2016, Published online: 26 Apr 2016

References

  • Alderton GK, Joenje H, Varon R, Børglum AD, Jeggo PA, O’Driscoll M. 2004. Seckel syndrome exhibits cellular features demonstrating defects in the ATR-signalling pathway. Hum Mol Genet. 13:3127–3138.
  • American Cancer Society. 2014. Second cancers in adults. [cited 2015 June 7]. Available from: http://www.cancer.org/acs/groups/cid/documents/webcontent/002043-pdf.pdf.
  • Bonassi S, Znaor A, Ceppi M, Lando C, Chang WP, Holland N, Kirsch-Volders M, Zeiger E, Ban S, Barale R, et al. 2007. An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans. Carcinogenesis. 28:625–631.
  • Braunstein S, Nakamura JL. 2013. Radiotherapy-induced malignancies: review of clinical features, pathobiology, and evolving approaches for mitigating risk. Front Oncol. 3:73.
  • Catena C, Conti D, Parasacchi P, Marenco P, Bortolato B, Botturi M, Leoni M, Portaluri M, Paleani-Vettori PG, Righi E. 1996. Micronuclei in cytokinesis-blocked lymphocytes may predict patient response to radiotherapy. Int J Radiat Biol. 70:301–308.
  • Chang WP, Hwang BF, Wang D, Wang JD. 1997. Cytogenetic effect of chronic low-dose, low-dose-rate gamma-radiation in residents of irradiated buildings. Lancet. 350:330–333.
  • Chuang SC, Scelo G, Tonita JM, Tamaro S, Jonasson JG, Kliewer EV, Hemminki K, Weiderpass E, Pukkala E, Tracey E, et al. 2008. Risk of second primary cancer among patients with head and neck cancers: a pooled analysis of 13 cancer registries. Int J Cancer. 123:2390–2396.
  • Cooper JS, Pajak TF, Rubin P, Tupchong L, Brady LW, Leibel SA, Laramore GE, Marcial VA, Davis LW, Cox JD. 1989. Second malignancies in patients who have head and neck cancer: incidence, effect on survival and implications based on the RTOG experience. Int J Radiat Oncol Biol Phys. 17:449–456.
  • Countryman PI, Heddle JA. 1976. The production of micronuclei from chromosome aberrations in irradiated cultures of human lymphocytes. Mutat Res. 41:321–332.
  • Deleyiannis FW, Thomas DB. 1997. Risk of lung cancer among patients with head and neck cancer. Otolaryngol Head Neck Surg. 116:630–636.
  • Donmez-Altuntas H, Bitgen N. 2012. Evaluation of the genotoxicity and cytotoxicity in the general population in Turkey by use of the cytokinesis-block micronucleus cytome assay. Mutat Res. 748:1–7.
  • Eastmond DA, Tucker JD. 1989. Identification of aneuploidy-inducing agents using cytokinesis-blocked human lymphocytes and an antikinetochore antibody. Environ Mol Mutagen. 13:34–43.
  • Elsendoorn TJ, Weijl NI, Mithoe S, Zwinderman AH, Van Dam F, De Zwart FA, Tates AD, Osanto S. 2001. Chemotherapy-induced chromosomal damage in peripheral blood lymphocytes of cancer patients supplemented with antioxidants or placebo. Mutat Res. 498:145–158.
  • El-Zein RA, Schabath MB, Etzel CJ, Lopez MS, Franklin JD, Spitz MR. 2006. Cytokinesis-blocked micronucleus assay as a novel biomarker for lung cancer risk. Cancer Res. 66:6449–6456.
  • El-Zein R, Vral A, Etzel CJ. 2011. Cytokinesis-blocked micronucleus assay and cancer risk assessment. Mutagenesis. 26:101–106.
  • Fenech M, Baghurst P, Luderer W, Turner J, Record S, Ceppi M, Bonassi S. 2005. Low intake of calcium, folate, nicotinic acid, vitamin E, retinol, b-carotene and high intake of pantothenic acid, biotin and riboflavin are significantly associated with increased genome instability – results from a dietary intake and micronucleus index survey in South Australia. Carcinogenesis. 26:991–999.
  • Fenech M. 2000. The in vitro micronucleus technique. Mutat Res. 455:81–95.
  • Fenech M, Morley AA. 1985. Measurement of micronuclei in lymphocytes. Mutat Res. 147:29–36.
  • Fenech M, Denham J, Francis W, Morley A. 1990. Micronuclei in cytokinesis-blocked lymphocytes of cancer patients following fractionated partial-body radiotherapy. Int J Radiat Biol. 57:373–383.
  • Franke RM, Kosloske AM, Lancaster CS, Filipski KK, Hu C, Zolk O, Mathijssen RH, Sparreboom A. 2010. Influence of Oct1/Oct2-deficiency on cisplatin-induced changes in urinary N-acetyl-beta-D-glucosaminidase. Clin Cancer Res. 16:4198–4206.
  • Fucic A, Gamulin M, Katic J, Milic M, Druzhinin V, Grgić M. 2013. Genome damage in testicular seminoma patients seven years after radiotherapy. Int J Radiat Biol. 89:928–933.
  • Gamulin M, Kopjar N, Grgić M, Ramić S, Bisof V, Garaj-Vrhovac V. 2008. Genome damage in oropharyngeal cancer patients treated by radiotherapy. Croat Med J. 49:515–527.
  • Gamulin M, Kopjar N, Grgić M, Ramić S, Viculin T, Petković M, Garaj-Vrhovac V. 2010. Cytogenetic follow-up in testicular seminoma patients exposed to adjuvant radiotherapy. Coll Antropol. 34:455–465.
  • Girard PM, Foray N, Stumm M, Waugh A, Riballo E, Maser RS, Phillips WP, Petrini J, Arlett CF, Jeggo PA. 2000. Radiosensitivity in Nijmegen Breakage Syndrome cells is attributable to a repair defect and not cell cycle checkpoint defects. Cancer Res. 60:4881–4888.
  • Hara W, Koyfman SA. 2015. General principles of radiation therapy for head and neck cancer. Uptodate [cited 2015 Aug 5]; Available from: http://www.uptodate.com
  • Jackson SP, Bartek J. 2009. The DNA-damage response in human biology and disease. Nature. 461:1071–1078.
  • Jagetia GC, Jayakrishnan A, Fernandes D, Vidyasagar MS. 2001. Evaluation of micronuclei frequency in the cultured peripheral blood lymphocytes of cancer patients before and after radiation treatment. Mutat Res. 491:9–16.
  • Kirsch-Volders M, Fenech M. 2001. Inclusion of micronuclei in non-divided mononuclear lymphocytes and necrosis/apoptosis may provide a more comprehensive cytokinesis block micronucleus assay for biomonitoring purposes. Mutagenesis. 16:51–58.
  • Kleinerman RA, Littlefield LG, Tarone RE, Sayer AM, Cookfair DL, Wactawski-Wende J, Inskip PD, Block A, Ramesh KH, Boice JD Jr. 1994. Chromosome aberrations in lymphocytes from women irradiated for benign and malignant gynecological disease. Radiat Res. 139:40–46.
  • Kliesch U, Adler ID. 1987. Micronucleus test in bone marrow of mice treated with 1-nitropropane, 2-nitropropane and cisplatin. Mutat Res. 192:181–184.
  • Lee TK, Allison RR, O’Brien KF, Naves JL, Karlsson UL, Wiley AL. 2002. Persistence of micronuclei in lymphocytes of cancer patients after radiotherapy. Radiat Res. 157:678–684.
  • León X, Quer M, Diez S, Orús C, López-Pousa A, Burgués J. 1999. Second neoplasm in patients with head and neck cancer. Head Neck. 21:204–210.
  • Lerner RA. 1972. Relationship of events at the lymphocyte cell surface to gene expression: approches to the problem. In: Inman FP, editor. Contemporary topics in immunochemistry. New York: Springer Science + Business Media; p. 111–144.
  • Luzhna L, Kathiria P, Kovalchuk O. 2013. Micronuclei in genotoxicity assessment: from genetics to epigenetics and beyond. Front Genet. 4:131.
  • Maluf SW, Erdtmann B. 2001. Genomic instability in Down syndrome and Fanconi anemia assessed by micronucleus analysis and single-cell gel electrophoresis. Cancer Genet Cytogenet. 124:71–75.
  • Mazur L, Czyzewska A, Augustynek A. 2000. WR-2721: inhibitor of cisplatin-induced micronuclei. Teratog Carcinog Mutagen. 20:349–356.
  • McDonald S, Haie C, Rubin P, Nelson D, Divers LD. 1989. Second malignant tumors in patients with laryngeal carcinoma: diagnosis, treatment, and prevention. Int J Radiat Oncol Biol Phys. 17:457–465.
  • Mikhalevich LS, De Zwart FA, Perepetskaya GA, Chebotareva NV, Mikhalevich EA, Tates AD. 2000. Radiation effects in lymphocytes of children living in a Chernobyl contaminated region of Belarus. Int J Radiat Biol. 76:1377–1385.
  • Milosević-Djordjević O, Grujiciĉ D, Vaskoviĉ Z, Marinkoviĉ D. 2010. High micronucleus frequency in peripheral blood lymphocytes of untreated cancer patients irrespective of gender, smoking and cancer sites. Tohoku J Exp Med. 220:115–120.
  • Murgia E, Ballardin M, Bonassi S, Rossi AM, Barale R. 2008. Validation of micronuclei frequency in peripheral blood lymphocytes as early cancer risk biomarker in a nested case-control study. Mutat Res. 639:27–34.
  • Padjas A, Lesisz D, Lankoff A, Banasik A, Lisowska H, Bakalarz R, Góźdź S, Wojcik A. 2005. Cytogenetic damage in lymphocytes of patients undergoing therapy for small cell lung cancer and ovarian carcinoma. Toxicol Appl Pharmacol. 209:183–191.
  • Scott D, Barber JB, Levine EL, Burrill W, Roberts SA. 1998. Radiation-induced micronucleus induction in lymphocytes identifies a high frequency of radiosensitive cases among breast cancer patients: a test for predisposition? Br J Cancer. 77:614–620.
  • Sekeroglu V, Sekeroglu ZA. 2011. [Micronucleus test for determining genotoxic damage]. Turk Hij Den Biyol Derg. 68:241–252.
  • Skiöld S. 2014. Radiation induced biomarkers of individual sensitivity to radiation therapy. PhD thesis. Stockholm University, Stockholm, Sweden.
  • Thomas P, Fenech M. 2011. Cytokinesis-block micronucleus cytome assay in lymphocytes. Methods Mol Biol. 682:217–234.
  • Tough DF, Sprent J. 1995. Life span of naive and memory T cells. Stem Cells. 13:242–249.
  • Tucker JD, Preston RJ. 1996. Chromosome aberrations, micronuclei, aneuploidy, sister chromatid exchanges, and cancer risk assessment. Mutat Res. 365:147–159.
  • Vignard J, Mirey G, Salles B. 2013. Ionizing-radiation induced DNA double-strand breaks: a direct and indirect lighting up. Radiother Oncol. 108:362–369.
  • Vral A, Thierens H, De Ridder L. 1996. Micronucleus induction by 60Co gamma-rays and fast neutrons in ataxia telangiectasia lymphocytes. Int J Radiat Biol. 70:171–176.

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